iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132469

Ensembl Protein ID

ENSXETP00000042042.3

UniProt Accession

F7CD46; F7CD46_XENTR

Genbank Protein ID

ENSXETP00000042042

Protein Name

Gem nuclear organelle-associated protein 5

Genbank Nucleotide ID

AAMC01011390

Gene Name

gemin5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000019404.3	ENSXETT00000042042.3	ENSXETP00000042042.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-40	134.7	64	100
UBD/Beta-Prp	1.90e-65	221.2	60	270

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.....sdtllvsGsdDgtikvWDlrt 32
           gHtd+v+++af     +++l +s+sdDgt+kvWD+ t
   Q: 64   GHTDRVSGFAFshfsgQSHLCASSSDDGTVKVWDTQT 100
           8************96533888*************876 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirv.wdletgqcl 129
            +l gh++ v+   fs+ +    + +++s+D+t+kvwd +t  +v   + h +++ +l++sp  +d lvsG++  ++ + w  ++++  
   Q: 60   GELVGHTDRVSGFAFSHFSGqshLCASSSDDGTVKVWDTQTKNTVTEHHLHRSTIAALHWSPlVKDLLVSGDEKGVLVCfWCNRNDSQQ 148
           57899999999999988655577***************************************888**************4544444433 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvyslsfdsng........................ 192
              + ++ +++ c++ +p + ++++ G +D+++ l d+ ++g++l++l+g h++ +++l++++                          
   Q: 149  ---FFPEPRTIFCLSCSPHKeDIVAIGYKDGMIVLVDIsRRGDVLHRLRG-HEEEIHCLEWSPHAlecdlqqkleetdlicfppteint 233
           ...677888899999888888*****************999********9.*********99977777777777777777777777888 PP
   S: 193  .............kelvsgsldgtvklwdlqtgecvr 216
                         +l+sgs+d+tv++w+ +tg+ v 
   Q: 234  angellpetenrrCYLASGSKDQTVRIWSASTGKAVT 270
           8888888888877778888888888888888887664 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MGEPDRMLSA SPNWYCSRSS DAAGGLFGFA ARNSVYLLNI NLQEPGFYGS GGFVFIFVSG 60
ELVGHTDRVS GFAFSHFSGQ SHLCASSSDD GTVKVWDTQT KNTVTEHHLH RSTIAALHWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGGAAC CAGATCGGAT GCTCAGTGCG TCACCCAACT GGTACTGTAG CCGCTCCAGT 60
GATGCTGCCG GTGGACTGTT CGGATTCGCT GCTCGAAATT CTGTCTACCT CCTGAACATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	55.90	0.00e+00	1622.00
IUUC-Apl-003586	Anas platyrhynchos	55.64	0.00e+00	1458.00
IUUC-Aca-004956	Anolis carolinensis	56.64	0.00e+00	1674.00
IUUC-Ame-010753	Astyanax mexicanus	63.57	0.00e+00	1001.00
IUUC-Bta-012315	Bos taurus	55.57	0.00e+00	1603.00
IUUC-Cja-019334	Callithrix jacchus	56.41	0.00e+00	1658.00
IUUC-Cfa-021254	Canis familiaris	55.82	0.00e+00	1648.00
IUUC-Cpo-021984	Cavia porcellus	55.15	0.00e+00	1555.00
IUUC-Csa-023650	Chlorocebus sabaeus	57.00	0.00e+00	1642.00
IUUC-Cho-024860	Choloepus hoffmanni	53.01	0.00e+00	1489.00
IUUC-Cin-025778	Ciona intestinalis	35.96	0.00e+00	632.00
IUUC-Csv-026313	Ciona savignyi	40.29	8.00e-162	563.00
IUUC-Dre-028096	Danio rerio	63.76	0.00e+00	1003.00
IUUC-Dno-029799	Dasypus novemcinctus	61.22	0.00e+00	1529.00
IUUC-Dor-030885	Dipodomys ordii	52.34	2.00e-113	404.00
IUUC-Ete-032918	Echinops telfairi	54.77	0.00e+00	1562.00
IUUC-Eca-034144	Equus caballus	56.12	0.00e+00	1603.00
IUUC-Eeu-034843	Erinaceus europaeus	53.55	0.00e+00	1180.00
IUUC-Fca-035948	Felis catus	55.77	0.00e+00	1616.00
IUUC-Fal-037303	Ficedula albicollis	55.63	0.00e+00	1643.00
IUUC-Gmo-039591	Gadus morhua	43.48	0.00e+00	907.00
IUUC-Gga-040570	Gallus gallus	54.14	0.00e+00	1426.00
IUUC-Gac-042646	Gasterosteus aculeatus	49.25	0.00e+00	1327.00
IUUC-Ggo-045605	Gorilla gorilla	55.00	0.00e+00	1241.00
IUUC-Hsa-046122	Homo sapiens	56.61	0.00e+00	1640.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	59.79	0.00e+00	1537.00
IUUC-Lch-050489	Latimeria chalumnae	53.42	4.00e-176	611.00
IUUC-Loc-052259	Lepisosteus oculatus	50.20	0.00e+00	1367.00
IUUC-Laf-053338	Loxodonta africana	55.90	0.00e+00	1636.00
IUUC-Mcc-055442	Macaca mulatta	56.89	0.00e+00	1644.00
IUUC-Meu-056245	Macropus eugenii	67.54	0.00e+00	705.00
IUUC-Mga-060202	Meleagris gallopavo	55.34	0.00e+00	1506.00
IUUC-Mmr-061730	Microcebus murinus	55.32	0.00e+00	1605.00
IUUC-Mdo-062880	Monodelphis domestica	57.85	0.00e+00	1679.00
IUUC-Mmu-063930	Mus musculus	67.03	0.00e+00	1060.00
IUUC-Mpu-066605	Mustela putorius furo	55.31	0.00e+00	1621.00
IUUC-Mlu-067765	Myotis lucifugus	56.53	0.00e+00	1645.00
IUUC-Nle-069183	Nomascus leucogenys	56.48	0.00e+00	1605.00
IUUC-Opr-070659	Ochotona princeps	45.34	8.00e-177	614.00
IUUC-Ont-072356	Oreochromis niloticus	61.53	0.00e+00	987.00
IUUC-Oan-073056	Ornithorhynchus anatinus	56.62	0.00e+00	1612.00
IUUC-Ocu-073881	Oryctolagus cuniculus	55.39	0.00e+00	1650.00
IUUC-Ola-087120	Oryzias latipes	55.39	6.00e-64	236.00
IUUC-Olu-087648	Ostreococcus lucimarinus	26.15	6.00e-35	142.00
IUUC-Oga-088343	Otolemur garnettii	57.19	0.00e+00	1649.00
IUUC-Oar-089257	Ovis aries	56.15	0.00e+00	1632.00
IUUC-Ptr-090497	Pan troglodytes	56.41	0.00e+00	1637.00
IUUC-Pan-092638	Papio anubis	56.88	0.00e+00	1639.00
IUUC-Psi-093096	Pelodiscus sinensis	57.04	0.00e+00	1422.00
IUUC-Pma-094571	Petromyzon marinus	41.63	2.00e-76	279.00
IUUC-Pfo-096742	Poecilia formosa	46.76	0.00e+00	1282.00
IUUC-Pab-098153	Pongo abelii	56.00	0.00e+00	1644.00
IUUC-Pca-100957	Procavia capensis	54.92	0.00e+00	1541.00
IUUC-Pva-102439	Pteropus vampyrus	55.87	0.00e+00	1644.00
IUUC-Rno-105891	Rattus norvegicus	56.70	0.00e+00	1573.00
IUUC-Sha-107181	Sarcophilus harrisii	57.62	0.00e+00	1595.00
IUUC-Ssc-115413	Sus scrofa	56.51	0.00e+00	1649.00
IUUC-Tgu-117082	Taeniopygia guttata	56.19	0.00e+00	1603.00
IUUC-Tru-118491	Takifugu rubripes	58.93	0.00e+00	931.00
IUUC-Tsy-119629	Tarsius syrichta	62.46	2.00e-111	397.00
IUUC-Tni-120240	Tetraodon nigroviridis	47.05	0.00e+00	1230.00
IUUC-Tbe-127673	Tupaia belangeri	50.34	0.00e+00	1307.00
IUUC-Ttr-128562	Tursiops truncatus	54.14	0.00e+00	1555.00
IUUC-Vpa-130596	Vicugna pacos	57.92	0.00e+00	1278.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence