iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074461

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02039378

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000011338.2	ENSOCUT00000011336.2	ENSOCUP00000009756.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.60e-11	42.1	13	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle+fk+ p+++pCgH f+++Cl + w     ++ + frCP Cr
   Q: 13   CSICLEPFKE-PVTTPCGHNFCRSCLdETW----AVQGPPFRCPQCR 54
           ********99.*******************....99**********8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAELLPLTEE LSCSICLEPF KEPVTTPCGH NFCRSCLDET WAVQGPPFRC PQCRTSYQVR 60
PQLHKNTVLC SVVERLAIVS TVAQVACDHC LKEPAVKTCF VCTASFCQEH LRPHLDSPAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC TGCTGCCCTT AACCGAAGAG CTGTCGTGCT CCATCTGCCT GGAGCCCTTC 60
AAGGAGCCGG TCACCACCCC GTGCGGCCAC AACTTCTGCC GCTCGTGCCT GGACGAGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR013320--ConA-like_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	57.19	0.00e+00	652.00
IUUC-Apl-004101	Anas platyrhynchos	50.00	1.00e-85	310.00
IUUC-Aca-005025	Anolis carolinensis	45.98	9.00e-89	321.00
IUUC-Bta-012735	Bos taurus	70.45	7.00e-156	543.00
IUUC-Cja-019996	Callithrix jacchus	67.98	2.00e-152	532.00
IUUC-Cfa-020466	Canis familiaris	52.84	6.00e-180	624.00
IUUC-Cpo-021737	Cavia porcellus	55.10	0.00e+00	629.00
IUUC-Csa-023217	Chlorocebus sabaeus	56.96	0.00e+00	664.00
IUUC-Cho-024346	Choloepus hoffmanni	49.83	4.00e-67	248.00
IUUC-Dno-030082	Dasypus novemcinctus	70.30	7.00e-153	534.00
IUUC-Dor-030335	Dipodomys ordii	52.20	1.00e-85	310.00
IUUC-Ete-032923	Echinops telfairi	64.27	1.00e-143	503.00
IUUC-Eca-033411	Equus caballus	56.77	0.00e+00	654.00
IUUC-Eeu-034656	Erinaceus europaeus	69.02	6.00e-147	514.00
IUUC-Fca-035371	Felis catus	56.28	0.00e+00	643.00
IUUC-Fal-037008	Ficedula albicollis	47.56	5.00e-90	325.00
IUUC-Gga-040608	Gallus gallus	47.81	2.00e-83	303.00
IUUC-Gac-041409	Gasterosteus aculeatus	33.89	2.00e-55	210.00
IUUC-Ggo-044518	Gorilla gorilla	68.60	2.00e-149	522.00
IUUC-Hsa-045828	Homo sapiens	57.12	0.00e+00	654.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	59.75	3.00e-128	452.00
IUUC-Lch-050478	Latimeria chalumnae	39.02	1.00e-70	260.00
IUUC-Loc-052864	Lepisosteus oculatus	33.67	2.00e-56	214.00
IUUC-Laf-054325	Loxodonta africana	71.93	2.00e-156	545.00
IUUC-Mcc-054920	Macaca mulatta	57.12	0.00e+00	665.00
IUUC-Meu-056367	Macropus eugenii	55.22	4.00e-63	236.00
IUUC-Mga-059975	Meleagris gallopavo	48.24	2.00e-81	296.00
IUUC-Mmr-060748	Microcebus murinus	68.35	9.00e-155	540.00
IUUC-Mdo-062904	Monodelphis domestica	45.02	8.00e-131	460.00
IUUC-Mmu-063891	Mus musculus	55.71	0.00e+00	648.00
IUUC-Mpu-066473	Mustela putorius furo	56.11	0.00e+00	654.00
IUUC-Mlu-068185	Myotis lucifugus	68.45	3.00e-150	525.00
IUUC-Nle-070177	Nomascus leucogenys	55.56	0.00e+00	649.00
IUUC-Opr-070558	Ochotona princeps	66.28	2.00e-155	541.00
IUUC-Ont-071368	Oreochromis niloticus	32.31	6.00e-53	202.00
IUUC-Ogu-078203	Oryza glumaepatula	47.14	2.00e-10	59.70
IUUC-Opu-083547	Oryza punctata	48.57	1.00e-10	60.50
IUUC-Oga-088937	Otolemur garnettii	51.31	2.00e-164	572.00
IUUC-Oar-089781	Ovis aries	50.89	4.00e-104	371.00
IUUC-Ptr-090771	Pan troglodytes	69.79	9.00e-152	530.00
IUUC-Pan-092830	Papio anubis	57.28	0.00e+00	666.00
IUUC-Psi-093664	Pelodiscus sinensis	49.73	2.00e-93	336.00
IUUC-Pma-094147	Petromyzon marinus	28.53	2.00e-38	153.00
IUUC-Pfo-096528	Poecilia formosa	33.42	1.00e-54	207.00
IUUC-Pab-097588	Pongo abelii	56.37	0.00e+00	645.00
IUUC-Pca-100890	Procavia capensis	70.03	2.00e-144	506.00
IUUC-Pva-102314	Pteropus vampyrus	58.22	3.00e-180	625.00
IUUC-Rno-105234	Rattus norvegicus	73.98	3.00e-151	528.00
IUUC-Sce-106362	Saccharomyces cerevisiae	42.86	6.00e-09	55.10
IUUC-Sha-106807	Sarcophilus harrisii	55.17	6.00e-104	371.00
IUUC-Sar-113283	Sorex araneus	59.35	4.00e-108	384.00
IUUC-Ssc-115878	Sus scrofa	74.68	4.00e-100	357.00
IUUC-Tgu-117026	Taeniopygia guttata	47.60	4.00e-58	219.00
IUUC-Tru-117794	Takifugu rubripes	35.67	3.00e-52	199.00
IUUC-Tbe-127580	Tupaia belangeri	67.20	9.00e-137	479.00
IUUC-Ttr-128648	Tursiops truncatus	51.97	2.00e-106	379.00
IUUC-Vpa-130254	Vicugna pacos	76.36	1.00e-42	166.00
IUUC-Xtr-132892	Xenopus tropicalis	41.98	3.00e-70	258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence