iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011740

Ensembl Protein ID

ENSAMXP00000010703.1

UniProt Accession

W5KSZ1; W5KSZ1_ASTMX

Genbank Protein ID

ENSAMXP00000010703

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01033872

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000010415.1	ENSAMXT00000010703.1	ENSAMXP00000010703.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-30	103.5	170	204
UBD/Beta-Prp	7.90e-49	166.7	135	381

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Htd v++l f +d    lvs+s+D+t++vWDl+++
   Q: 170  HTDIVRDLTFaPDgsLVLVSASRDKTLRVWDLKDD 204
           ***********8864558*************9887 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            kf +d+ llatg  +g+ik+wd+ tgkll  l +h++ v++++f pdg+ +lv++s+D+t++vwdl+ +g +v +l+gh++ v++ +f
   Q: 135  FKFGQDQLLLATGLNNGRIKIWDAYTGKLLLNLMDHTDIVRDLTFAPDGSlVLVSASRDKTLRVWDLKdDGNMVKVLRGHQNWVYCSAF 223
           68899999******************************************99***************989******************* PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp++++l s ++ + + +w++++++ ++  l+gh+  v + +++pdg ll+++s+D+ v +Wd  +g++l +l             g++
   Q: 224  SPDSSVLCSVGAGKSVFLWNMDKYTMIR-KLEGHHNDVVSCEFSPDGALLATASYDTRVIVWDPHMGTVLLELghlfpppspifaGGAN 311
           ****************************.999999999999*******************************************9888* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           ++ v+s++f ++g++++s+ +d+ v++w++ +++   +  +  +n ++ +fs ++  l+ gs Dgs+ +W +
   Q: 312  DRWVRSVAFCHDGQHIASITDDRLVRFWSIDEKS--PQAVASLTNGLCCAFSTDGSVLAAGSRDGSVHFWSC 381
           ******************************9885..8889999***************************76 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MASFPDSINE NEIGKAKFIG ELLAPVAPFD QKSGRETWTV AFAPDGSYFA WSQGHRIVRL 60
VPWSKCIKNF SMRKEERING AGPRRLSRQG SDVALVPGEP REHTIDCGDI VWGLAFGSSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGCGGTGA CGTTGTTGAG AGTAGCCCGC CCACTAGACT GAGTGTGAAG TGCGGACCAG 60
CCGCGGCCAT TAGATTAGAC TGTACACAGA CGGAGCGGAG AGACCGAGCG GAGCCCGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	75.30	0.00e+00	663.00
IUUC-Apl-003903	Anas platyrhynchos	75.25	0.00e+00	657.00
IUUC-Aca-005214	Anolis carolinensis	66.67	2.00e-172	598.00
IUUC-Bta-013475	Bos taurus	75.53	0.00e+00	668.00
IUUC-Cja-019053	Callithrix jacchus	74.88	0.00e+00	676.00
IUUC-Cfa-020103	Canis familiaris	75.77	0.00e+00	667.00
IUUC-Cpo-022438	Cavia porcellus	74.58	0.00e+00	671.00
IUUC-Csa-024062	Chlorocebus sabaeus	75.06	0.00e+00	679.00
IUUC-Cho-024334	Choloepus hoffmanni	67.70	4.00e-166	577.00
IUUC-Cin-025590	Ciona intestinalis	41.31	2.00e-78	286.00
IUUC-Csv-026023	Ciona savignyi	41.20	4.00e-79	288.00
IUUC-Dre-028089	Danio rerio	90.07	0.00e+00	801.00
IUUC-Dno-029436	Dasypus novemcinctus	78.95	1.00e-160	559.00
IUUC-Dor-031107	Dipodomys ordii	71.26	3.00e-175	607.00
IUUC-Ete-032326	Echinops telfairi	75.86	0.00e+00	646.00
IUUC-Eca-033401	Equus caballus	75.77	0.00e+00	667.00
IUUC-Eeu-034520	Erinaceus europaeus	74.58	0.00e+00	670.00
IUUC-Fca-036386	Felis catus	75.53	0.00e+00	667.00
IUUC-Fal-036616	Ficedula albicollis	73.77	0.00e+00	642.00
IUUC-Gmo-039335	Gadus morhua	81.17	0.00e+00	684.00
IUUC-Gga-040856	Gallus gallus	75.53	0.00e+00	677.00
IUUC-Gac-042140	Gasterosteus aculeatus	83.84	0.00e+00	750.00
IUUC-Ggo-044619	Gorilla gorilla	75.06	0.00e+00	680.00
IUUC-Hsa-046300	Homo sapiens	75.06	0.00e+00	678.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	75.06	0.00e+00	679.00
IUUC-Lch-049550	Latimeria chalumnae	73.54	9.00e-159	552.00
IUUC-Loc-051769	Lepisosteus oculatus	83.65	0.00e+00	732.00
IUUC-Laf-054576	Loxodonta africana	76.25	0.00e+00	672.00
IUUC-Mcc-054666	Macaca mulatta	75.00	4.00e-124	437.00
IUUC-Meu-055989	Macropus eugenii	74.50	1.00e-158	552.00
IUUC-Mga-059722	Meleagris gallopavo	74.15	0.00e+00	662.00
IUUC-Mmr-060970	Microcebus murinus	75.30	0.00e+00	662.00
IUUC-Mdo-062249	Monodelphis domestica	64.13	8.00e-154	536.00
IUUC-Mmu-063742	Mus musculus	73.16	0.00e+00	657.00
IUUC-Mpu-066518	Mustela putorius furo	75.77	0.00e+00	682.00
IUUC-Mlu-068063	Myotis lucifugus	75.30	0.00e+00	655.00
IUUC-Nle-069561	Nomascus leucogenys	75.30	0.00e+00	681.00
IUUC-Opr-071158	Ochotona princeps	72.51	0.00e+00	654.00
IUUC-Ont-072542	Oreochromis niloticus	82.67	0.00e+00	738.00
IUUC-Oan-073217	Ornithorhynchus anatinus	76.30	0.00e+00	682.00
IUUC-Ocu-074251	Oryctolagus cuniculus	74.94	0.00e+00	645.00
IUUC-Ola-086549	Oryzias latipes	80.24	0.00e+00	725.00
IUUC-Oga-088382	Otolemur garnettii	75.30	0.00e+00	663.00
IUUC-Oar-090263	Ovis aries	74.58	0.00e+00	666.00
IUUC-Ptr-090922	Pan troglodytes	75.06	0.00e+00	679.00
IUUC-Pan-092518	Papio anubis	75.06	0.00e+00	679.00
IUUC-Psi-093512	Pelodiscus sinensis	76.01	0.00e+00	681.00
IUUC-Pma-094324	Petromyzon marinus	59.12	2.00e-139	488.00
IUUC-Pfo-096264	Poecilia formosa	83.06	0.00e+00	746.00
IUUC-Pab-098018	Pongo abelii	73.87	0.00e+00	665.00
IUUC-Pca-101034	Procavia capensis	74.45	5.00e-179	620.00
IUUC-Pva-102862	Pteropus vampyrus	72.68	9.00e-176	609.00
IUUC-Rno-106116	Rattus norvegicus	74.11	0.00e+00	669.00
IUUC-Sha-106952	Sarcophilus harrisii	72.97	0.00e+00	642.00
IUUC-Sar-113211	Sorex araneus	70.22	2.00e-126	444.00
IUUC-Ssc-116440	Sus scrofa	75.53	0.00e+00	665.00
IUUC-Tgu-116675	Taeniopygia guttata	74.26	0.00e+00	642.00
IUUC-Tru-118295	Takifugu rubripes	80.47	0.00e+00	707.00
IUUC-Tsy-118916	Tarsius syrichta	64.85	3.00e-159	554.00
IUUC-Tni-120302	Tetraodon nigroviridis	80.33	0.00e+00	706.00
IUUC-Tbe-127416	Tupaia belangeri	64.95	2.00e-152	531.00
IUUC-Ttr-128185	Tursiops truncatus	75.77	0.00e+00	667.00
IUUC-Xtr-132465	Xenopus tropicalis	75.18	0.00e+00	681.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence