iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118295

UUCD1 version

UUC-TaR-00220

Ensembl Protein ID

ENSTRUP00000011664.1

UniProt Accession

H2SGY2; H2SGY2_TAKRU

Protein Name

WD repeat and SOCS box-containing protein 1

Gene Name

wsb1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000004887.1	ENSTRUT00000011724.1	ENSTRUP00000011664.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.30e-28	96.9	174	208
UBD/Beta-Prp	6.30e-47	161.4	139	385

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Htd v++l f +d   +lvs+s D+t++vWDl+++
   Q: 174  HTDIVRDLTFaPDgsLMLVSASTDKTLRVWDLKDD 208
           ***********7767889*************9887 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            +f +d+ llatg  +g+ik+wdv tg+ll  l +h++ v++++f pdg+ +lv++s+D+t++vwdl+ +g +v +l gh ++v+s +f
   Q: 139  FQFGRDQLLLATGLNNGRIKIWDVYTGTLLLNLMDHTDIVRDLTFAPDGSlMLVSASTDKTLRVWDLKdDGNMVKVLWGHPNRVYSSAF 227
           67889999******************************************99***************9899****************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp++++l s ++ + + +w++++++ ++  l+gh+  v + +++pdg ll+++s+D+ v +Wd ++g++l +l             g++
   Q: 228  SPDSSVLCSVGASKAVLLWNMDKYTLIR-KLEGHHNDVVSCEFSPDGALLATASYDTRVIVWDHQRGSILLELghlfpppspifaGGAN 315
           ****************************.999999999999*******************************************9888* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           ++ v+s+sf  +g++++s+s+d+ v++w++++     +  +   n ++ +fs  +  l+ g++Dgs+ +W +
   Q: 316  DRWVRSVSFCADGRHIASVSDDRLVRFWSIEER--APQAVASLPNGLCCAFSTTGSVLAAGTCDGSVHFWEC 385
           ******************************877..68889999999999*********************77 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MASFPESVNE NDIDKAKFIG ELLVPMAPFD QKAGREAWTV AFAPDGSYFA WSQGHRIVRL 60
IPWAKCLSSF SVRHGGEVTN PTSPRHLSRQ SCKGGSVIPM AGAPPEHTID CGGIVWGMAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAAGCT TCCCAGAATC TGTAAACGAA AATGATATAG GTAAGTTCGA TGCGACCTCT 60
TTCTTTTTCT GAAATCCGCG TTTCCGTTTC CAGCGTGCTC GTTGTCCGCG TCCGTCTGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR023294--Tachylectin2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	71.60	1.00e-180	625.00
IUUC-Apl-003903	Anas platyrhynchos	71.84	2.00e-178	618.00
IUUC-Aca-005214	Anolis carolinensis	63.34	7.00e-160	556.00
IUUC-Ame-011740	Astyanax mexicanus	80.47	0.00e+00	707.00
IUUC-Bta-013475	Bos taurus	72.54	0.00e+00	631.00
IUUC-Cja-019053	Callithrix jacchus	72.64	0.00e+00	639.00
IUUC-Cfa-020103	Canis familiaris	72.07	0.00e+00	630.00
IUUC-Cpo-022438	Cavia porcellus	71.83	0.00e+00	639.00
IUUC-Csa-024062	Chlorocebus sabaeus	73.00	0.00e+00	645.00
IUUC-Cho-024334	Choloepus hoffmanni	64.79	1.00e-155	542.00
IUUC-Cin-025590	Ciona intestinalis	41.15	6.00e-75	274.00
IUUC-Csv-026023	Ciona savignyi	41.00	1.00e-74	273.00
IUUC-Dre-028089	Danio rerio	79.63	0.00e+00	699.00
IUUC-Dno-029436	Dasypus novemcinctus	75.85	1.00e-149	522.00
IUUC-Dor-031107	Dipodomys ordii	67.37	1.00e-163	569.00
IUUC-Ete-032326	Echinops telfairi	71.95	1.00e-175	608.00
IUUC-Eca-033401	Equus caballus	71.83	0.00e+00	629.00
IUUC-Eeu-034520	Erinaceus europaeus	70.66	0.00e+00	627.00
IUUC-Fca-036386	Felis catus	71.83	0.00e+00	627.00
IUUC-Fal-036616	Ficedula albicollis	70.12	4.00e-176	610.00
IUUC-Gmo-039335	Gadus morhua	77.72	0.00e+00	653.00
IUUC-Gga-040856	Gallus gallus	72.30	0.00e+00	637.00
IUUC-Gac-042140	Gasterosteus aculeatus	84.07	0.00e+00	750.00
IUUC-Ggo-044619	Gorilla gorilla	73.00	0.00e+00	647.00
IUUC-Hsa-046300	Homo sapiens	72.54	0.00e+00	643.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	71.83	0.00e+00	641.00
IUUC-Lch-049550	Latimeria chalumnae	72.13	8.00e-149	519.00
IUUC-Loc-051769	Lepisosteus oculatus	77.41	0.00e+00	674.00
IUUC-Laf-054576	Loxodonta africana	73.47	0.00e+00	637.00
IUUC-Mcc-054666	Macaca mulatta	76.34	2.00e-118	417.00
IUUC-Meu-055989	Macropus eugenii	73.35	7.00e-150	523.00
IUUC-Mga-059722	Meleagris gallopavo	72.09	4.00e-180	624.00
IUUC-Mmr-060970	Microcebus murinus	72.07	0.00e+00	629.00
IUUC-Mdo-062249	Monodelphis domestica	62.21	7.00e-145	506.00
IUUC-Mmu-063742	Mus musculus	71.06	0.00e+00	628.00
IUUC-Mpu-066518	Mustela putorius furo	71.83	0.00e+00	639.00
IUUC-Mlu-068063	Myotis lucifugus	70.89	1.00e-177	615.00
IUUC-Nle-069561	Nomascus leucogenys	72.77	0.00e+00	645.00
IUUC-Opr-071158	Ochotona princeps	69.41	9.00e-177	612.00
IUUC-Ont-072542	Oreochromis niloticus	85.25	0.00e+00	756.00
IUUC-Oan-073217	Ornithorhynchus anatinus	73.41	0.00e+00	647.00
IUUC-Ocu-074251	Oryctolagus cuniculus	71.84	1.00e-176	612.00
IUUC-Ola-086549	Oryzias latipes	80.33	0.00e+00	725.00
IUUC-Oga-088382	Otolemur garnettii	71.60	0.00e+00	630.00
IUUC-Oar-090263	Ovis aries	71.36	0.00e+00	625.00
IUUC-Ptr-090922	Pan troglodytes	72.54	0.00e+00	644.00
IUUC-Pan-092518	Papio anubis	73.00	0.00e+00	645.00
IUUC-Psi-093512	Pelodiscus sinensis	72.54	0.00e+00	636.00
IUUC-Pma-094324	Petromyzon marinus	57.18	1.00e-132	466.00
IUUC-Pfo-096264	Poecilia formosa	84.78	0.00e+00	762.00
IUUC-Pab-098018	Pongo abelii	71.13	0.00e+00	629.00
IUUC-Pca-101034	Procavia capensis	71.12	6.00e-169	586.00
IUUC-Pva-102862	Pteropus vampyrus	68.54	2.00e-164	571.00
IUUC-Rno-106116	Rattus norvegicus	71.60	0.00e+00	632.00
IUUC-Sha-106952	Sarcophilus harrisii	69.95	3.00e-173	600.00
IUUC-Sar-113211	Sorex araneus	65.02	4.00e-117	414.00
IUUC-Ssc-116440	Sus scrofa	71.83	0.00e+00	628.00
IUUC-Tgu-116675	Taeniopygia guttata	70.63	2.00e-174	604.00
IUUC-Tsy-118916	Tarsius syrichta	61.74	1.00e-150	525.00
IUUC-Tni-120302	Tetraodon nigroviridis	91.10	0.00e+00	811.00
IUUC-Tbe-127416	Tupaia belangeri	62.14	3.00e-145	508.00
IUUC-Ttr-128185	Tursiops truncatus	72.30	0.00e+00	630.00
IUUC-Xtr-132465	Xenopus tropicalis	70.26	0.00e+00	626.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence