iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132277

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 53

Genbank Nucleotide ID

AAMC01031783

Gene Name

usp53

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000004044.2	ENSXETT00000008750.2	ENSXETP00000008750.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-24	86.7	39	350

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 7    gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee...fsgyeqqDa 92
           +N+C++NS++Q+L+++  +r+ l   + + +        ++++ ++l+++f+++++s++k+    ++ +al++  +    f+     Da
   Q: 39   QNSCFLNSAVQVLWQLDIFRRSLRGLTGHVCLG------DACIFCALKSIFAQFQTSREKVLPSDAMRHALAESFKDehrFQLGLMDDA 121
           7************************77777765......47*************7666665555555555554433222299******* PP
   S: 93   qEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkee 181
            E+++ +l++++ ++                     ++e +  ++++++ ++ F ++l +q++c +c+ +s    pf+++   ++    
   Q: 122  AECFENILQRIHFHI-------------------VPNSEGDMCTSKSCITHQKFAMTLYEQCVCRSCGASSDPL-PFTEFVRYISTTAL 190
           ***************...................122356679999**********************999655.88888888886666 PP
   S: 182  tkke........slq.dcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +++          l+ +++++  ++ + +++ +   ++c ++ +  +++ l ++Pe+ ++ L +   s + +  e + +++ + l L  
   Q: 191  CNEVdrmlerheRLKpEMFADLLQAANTTDDYRKCPSNCGQRIK-IRRV-LMNCPEIVTIGLVWD--SDNSDLTEDVVRNLATQLYLPG 275
           65446666667655536779999999998877677777777665.4444.6678**********9..4444555555555555433333 PP
   S: 262  spfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvlfYk 336
             f +++e+  ke++ Y L+++++++      HY+a+++++k   W+lfdD +V+ev  k+++v++++     ++ +lfY 
   Q: 276  LFFRVTDEQ-AKESRLY-LVGMICYTS----KHYCAFAYHTKSAkWFLFDDASVKEVgtKWKDVVTKCIrchYQPLLLFYA 350
           333333333.3335666.*******87....9********76656***********9767899999776888999999996 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MAWVKLFRRQ AGGNLGKVYQ PGSVLSLAPT KGLFNEPGQN SCFLNSAVQV LWQLDIFRRS 60
LRGLTGHVCL GDACIFCALK SIFAQFQTSR EKVLPSDAMR HALAESFKDE HRFQLGLMDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGGAATCT ACCATACTTA GAAAGGGGGG ACGCAAAAAG CCGCAGTTTT TGGATCCTGA 60
TCGTAAAGGA GCAGCGGACA GTAAGGGGAA AATGGGTCCT CCGAGAATGG CCGGAGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002136	Ailuropoda melanoleuca	66.71	0.00e+00	941.00
IUUC-Apl-003843	Anas platyrhynchos	63.99	0.00e+00	924.00
IUUC-Aca-004689	Anolis carolinensis	63.05	0.00e+00	911.00
IUUC-Ame-010673	Astyanax mexicanus	68.97	5.00e-180	624.00
IUUC-Bta-012434	Bos taurus	63.61	0.00e+00	928.00
IUUC-Cja-019625	Callithrix jacchus	66.02	0.00e+00	959.00
IUUC-Cfa-020038	Canis familiaris	66.53	0.00e+00	937.00
IUUC-Cpo-021503	Cavia porcellus	63.65	0.00e+00	946.00
IUUC-Csa-024021	Chlorocebus sabaeus	64.65	0.00e+00	932.00
IUUC-Cho-024769	Choloepus hoffmanni	61.41	0.00e+00	818.00
IUUC-Dre-028438	Danio rerio	68.31	4.00e-179	621.00
IUUC-Dno-029317	Dasypus novemcinctus	63.48	0.00e+00	905.00
IUUC-Dor-030249	Dipodomys ordii	85.71	0.00e+00	714.00
IUUC-Ete-032403	Echinops telfairi	64.93	0.00e+00	947.00
IUUC-Eca-033216	Equus caballus	66.62	0.00e+00	942.00
IUUC-Eeu-035319	Erinaceus europaeus	63.23	3.00e-134	473.00
IUUC-Fca-036414	Felis catus	64.23	0.00e+00	945.00
IUUC-Fal-036886	Ficedula albicollis	63.84	0.00e+00	939.00
IUUC-Gmo-038617	Gadus morhua	73.20	1.00e-165	575.00
IUUC-Gga-040930	Gallus gallus	64.30	0.00e+00	942.00
IUUC-Gac-041327	Gasterosteus aculeatus	75.07	7.00e-169	586.00
IUUC-Ggo-045573	Gorilla gorilla	64.90	0.00e+00	934.00
IUUC-Hsa-046741	Homo sapiens	64.05	0.00e+00	924.00
IUUC-Itr-048229	Ictidomys tridecemlineatus	61.23	0.00e+00	826.00
IUUC-Lch-049932	Latimeria chalumnae	59.54	0.00e+00	824.00
IUUC-Loc-052180	Lepisosteus oculatus	56.93	0.00e+00	791.00
IUUC-Laf-054545	Loxodonta africana	65.11	0.00e+00	934.00
IUUC-Mcc-054918	Macaca mulatta	64.77	0.00e+00	938.00
IUUC-Meu-056802	Macropus eugenii	57.57	0.00e+00	784.00
IUUC-Mga-059684	Meleagris gallopavo	62.50	0.00e+00	878.00
IUUC-Mmr-061644	Microcebus murinus	86.19	1.00e-176	611.00
IUUC-Mdo-062636	Monodelphis domestica	61.90	0.00e+00	866.00
IUUC-Mmu-063910	Mus musculus	64.33	0.00e+00	882.00
IUUC-Mac-064469	Musa acuminata	33.71	7.00e-19	90.10
IUUC-Mpu-065796	Mustela putorius furo	60.84	0.00e+00	855.00
IUUC-Nle-069276	Nomascus leucogenys	64.26	0.00e+00	895.00
IUUC-Opr-070545	Ochotona princeps	48.81	2.00e-135	476.00
IUUC-Ont-072449	Oreochromis niloticus	53.17	0.00e+00	682.00
IUUC-Oan-073493	Ornithorhynchus anatinus	55.06	0.00e+00	665.00
IUUC-Ocu-074445	Oryctolagus cuniculus	63.81	0.00e+00	894.00
IUUC-Ola-087574	Oryzias latipes	66.17	9.00e-156	542.00
IUUC-Oga-087977	Otolemur garnettii	64.47	0.00e+00	863.00
IUUC-Oar-089584	Ovis aries	62.84	0.00e+00	916.00
IUUC-Ptr-091610	Pan troglodytes	64.26	0.00e+00	921.00
IUUC-Pan-091828	Papio anubis	61.08	0.00e+00	839.00
IUUC-Psi-093643	Pelodiscus sinensis	66.16	0.00e+00	952.00
IUUC-Ppa-095930	Physcomitrella patens	33.43	3.00e-42	167.00
IUUC-Pfo-096829	Poecilia formosa	57.41	4.00e-175	608.00
IUUC-Pab-098190	Pongo abelii	64.52	0.00e+00	921.00
IUUC-Pva-102372	Pteropus vampyrus	59.30	0.00e+00	842.00
IUUC-Sha-107092	Sarcophilus harrisii	64.23	0.00e+00	885.00
IUUC-Sly-110975	Solanum lycopersicum	31.40	5.00e-40	160.00
IUUC-Sar-113376	Sorex araneus	46.52	1.00e-106	380.00
IUUC-Ssc-115969	Sus scrofa	64.32	0.00e+00	911.00
IUUC-Tgu-117134	Taeniopygia guttata	65.26	0.00e+00	941.00
IUUC-Tru-118240	Takifugu rubripes	67.96	1.00e-157	548.00
IUUC-Tsy-119297	Tarsius syrichta	70.74	7.00e-179	620.00
IUUC-Tni-120116	Tetraodon nigroviridis	73.70	1.00e-163	568.00
IUUC-Tbe-127607	Tupaia belangeri	64.78	0.00e+00	918.00
IUUC-Ttr-128647	Tursiops truncatus	64.33	0.00e+00	876.00
IUUC-Vpa-130288	Vicugna pacos	60.95	0.00e+00	848.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence