iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115859

Ensembl Protein ID

ENSSSCP00000027061.1

UniProt Accession

I3LSG8; I3LSG8_PIG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000029463.1	ENSSSCT00000028858.1	ENSSSCP00000027061.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-56	186.3	477	512
UBD/Beta-Prp	5.20e-81	272.4	350	593

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gHt+sv+ ++f +d +ll+s+s Dgt+k+WD+++ +
   Q: 477  GHTNSVSHCRFsPDdKLLASCSADGTLKLWDVKSAN 512
           8***********777****************98765 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h++ ++  +fs+d++ +a+ ++d+t++v++++tg +l +++ he+ev ++ fs d+ +++t+s D+ +k+w+  tg+ v+++ +h+++v
   Q: 350  HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSADDRFIATCSVDKKVKIWNSVTGELVQSYDEHSEQV 438
           6777788********************************************************************************** PP
   S: 98   lslsfsp..sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.....ktgkllrtl.... 175
            +++f    +   l++Gs+d  +++wdl++++c + t  gh+ +v++ +++pd++ll+s+s+D+t++lWd+     +     +      
   Q: 439  NCCHFTNnsNHLLLATGSSDYFLKLWDLNQKECRN-TMFGHTNSVSHCRFSPDDKLLASCSADGTLKLWDVksaneR-----KSInvkq 521
           ******954447789********************.***********************************555542.....4444444 PP
   S: 176  ........tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec.vrtlnghtdnvksvrfspnderlvs 239
                   +++ + +v++ s++ +g +lv ++++ +v l++++tg    ++ +gh ++++  +fsp +++ v+
   Q: 522  fflnseesQEDMEVMVKCCSWSADGASLVVAAKN-KVLLFNIHTGGLlAEIHTGHHSTIQYCDFSPSNHLAVV 593
           48998777666777888888********998876.57799**987662667789***********88877665 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

RSLLILDDIW DPWVLKAFDN QCQILLTTRD KSVTDSVMGP KYVIPVESGL GKEKGLEILS 60
LFVNMKKADL PEQAHSIIKE CKGIPLNFIC RFFKNFFLFW NFYINLLALK IIFFHRFCLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTCTCTGT TGATCTTGGA TGATATTTGG GATCCTTGGG TATTAAAAGC TTTTGACAAT 60
CAGTGTCAGA TTCTTCTTAC AACTAGAGAC AAGAGTGTTA CAGATTCAGT AATGGGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR009072--Histone-fold
IPR002182--NB-ARC
IPR027417--P-loop_NTPase
IPR027295--Quinoprotein_ADH-like_fam
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00931--NB-ARC
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0043293--C:apoptosome
GO:0016021--C:integral component of membrane
GO:0043531--F:ADP binding
GO:0008656--F:cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0008635--P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence