iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-072894

Ensembl Protein ID

ENSOANP00000024516.1

UniProt Accession

F7E7Q4; F7E7Q4_ORNAN

Protein Name

Uncharacterized protein

Gene Name

HTR2A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000015564.2	ENSOANT00000024520.2	ENSOANP00000024516.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	25.68	3.60e-01	31.20	IUUC-Sce-106188

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MDILCEEEST VTQTANSLIQ LNHDRSLLKA DFISGEANIS DVLNWTVDAE NLTNVSCEGN 60
LTPPCNVLFH VQEKNWPALL TAVVIILTIA GNILVIMAVS LEKKLQNATN YFLMSLAIAD 120

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Nucleotide Sequence
(Fasta)

CTCTCTTTTC CACAATTCCA TCTCCACCAA GCTCAGGCTT AGAAATGGAT ATTCTTTGTG 60
AAGAGGAGAG TACTGTGACC CAAACTGCCA ACTCCCTAAT CCAACTAAAT CATGACCGAA 120

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Sequence Source

Ensembl

Keyword

KW-1003--Cell membrane
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0297--G-protein coupled receptor
KW-0472--Membrane
KW-0675--Receptor
KW-1185--Reference proteome
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000455--5HT2A_rcpt
IPR002231--5HT_rcpt
IPR000276--GPCR_Rhodpsn
IPR017452--GPCR_Rhodpsn_7TM

PROSITE

PS00237--G_PROTEIN_RECEP_F1_1
PS50262--G_PROTEIN_RECEP_F1_2

Pfam

PF00001--7tm_1

PRINTS

PR00516--5HT2ARECEPTR
PR01101--5HTRECEPTOR
PR00237--GPCRRHODOPSN

SMART

SM01381--7TM_GPCR_Srsx

Gene Ontology

GO:0043198--C:dendritic shaft
GO:0005887--C:integral component of plasma membrane
GO:0005622--C:intracellular
GO:0071886--F:1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
GO:0008144--F:drug binding
GO:0004993--F:G-protein coupled serotonin receptor activity
GO:0030594--F:neurotransmitter receptor activity
GO:0051378--F:serotonin binding
GO:0007202--P:activation of phospholipase C activity
GO:0014065--P:phosphatidylinositol 3-kinase signaling
GO:0007200--P:phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0045600--P:positive regulation of fat cell differentiation
GO:0045821--P:positive regulation of glycolytic process
GO:0033674--P:positive regulation of kinase activity
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0010513--P:positive regulation of phosphatidylinositol biosynthetic process
GO:0044380--P:protein localization to cytoskeleton
GO:0050795--P:regulation of behavior
GO:0046883--P:regulation of hormone secretion
GO:0051209--P:release of sequestered calcium ion into cytosol
GO:0042493--P:response to drug
GO:0006939--P:smooth muscle contraction

KEGG

oaa:100083607

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013064	Bos taurus	24.58	2.00e-04	39.30
IUUC-Cfa-020374	Canis familiaris	25.74	2.60e-02	32.00
IUUC-Cpo-022123	Cavia porcellus	19.05	7.00e-03	33.90
IUUC-Cho-024984	Choloepus hoffmanni	25.79	5.00e-16	77.80
IUUC-Csv-026250	Ciona savignyi	31.25	5.30e-01	28.50
IUUC-Ggo-045592	Gorilla gorilla	25.00	2.10e-02	32.70
IUUC-Hsa-046384	Homo sapiens	22.65	1.70e-02	32.70
IUUC-Itr-048454	Ictidomys tridecemlineatus	24.20	2.00e-04	38.90
IUUC-Lch-049802	Latimeria chalumnae	31.74	2.00e-25	109.00
IUUC-Loc-052069	Lepisosteus oculatus	30.03	8.00e-39	154.00
IUUC-Mmr-061649	Microcebus murinus	24.00	2.20e-01	28.90
IUUC-Mdo-062558	Monodelphis domestica	26.52	1.00e-23	102.00
IUUC-Mlu-067297	Myotis lucifugus	24.05	3.00e-04	38.50
IUUC-Ome-081302	Oryza meridionalis	29.79	6.40e-01	28.50
IUUC-Ola-087063	Oryzias latipes	25.33	2.00e-05	43.50
IUUC-Ptr-091524	Pan troglodytes	22.95	2.60e-02	32.00
IUUC-Pfo-096201	Poecilia formosa	25.00	6.00e-13	67.80
IUUC-Pva-103210	Pteropus vampyrus	37.50	2.10e+00	26.60
IUUC-Rno-105954	Rattus norvegicus	22.97	4.80e-01	27.70
IUUC-Sce-106188	Saccharomyces cerevisiae	25.68	1.20e-01	31.20
IUUC-Sha-107148	Sarcophilus harrisii	29.18	2.00e-40	158.00
IUUC-Ssc-115447	Sus scrofa	23.08	1.40e-01	29.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence