iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116218

Ensembl Protein ID

ENSSSCP00000023723.1

UniProt Accession

I3LI24; I3LI24_PIG

Protein Name

Uncharacterized protein

Gene Name

GNB2L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000029724.1	ENSSSCT00000022602.1	ENSSSCP00000023723.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-41	137.8	147	181
UBD/Beta-Prp	1.40e-52	179.0	10	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf....sdtllvsGsdDgtikvWDlrt 32
           H+++v+c++f    s++++vs+++D+ + vW+l  
   Q: 147  HSEWVSCVRFspnsSNPIIVSCGWDKLVNVWNLAN 181
           9**********98544****************865 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcv 87
           tlkgh+  v +  + ++ ++l+++  rd+ti+ w++t+  +      r l gh+ +v++v +s+dg++ ++gs D+t+++wdl tg+++
   Q: 10   TLKGHNGWVTQLSAHAETQRLFLSCRRDKTIIMWKLTRDETnygipQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTT 98
           7889999888877779999*******************999************************************************ PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdlktgkllr 173
           + + gh+++vls++fs ++  +vsGs+d+ti++w++  g c ++  ++ h+++v+cv+++p++   ++vs++ D+ v++W+l++ kl +
   Q: 99   RRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTvQDESHSEWVSCVRFSPNSsnPIIVSCGWDKLVNVWNLANCKLKT 186
           **********************************765.45555447899************998569***************7777776 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgd 255
              g ht++ + ++++++g  ++sg++dg+  lwdl +g+ ++tl g  d ++ + fs  + + ++++  +si+iWdl+ + 
   Q: 187  NHIG-HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFS-PNRYWLCAATGPSIKIWDLEGKI 265
           6676.****************************************996.577878888.7888899999********98665 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MTEQMTLRGT LKGHNGWVTQ LSAHAETQRL FLSCRRDKTI IMWKLTRDET NYGIPQRALR 60
GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGAAC AGATGACTCT CCGTGGCACC CTCAAGGGCC ATAACGGCTG GGTGACCCAG 60
ANNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0070062--C:extracellular exosome
GO:1990630--C:IRE1-RACK1-PP2A complex
GO:0030496--C:midbody
GO:0005739--C:mitochondrion
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0001891--C:phagocytic cup
GO:0008656--F:cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0008200--F:ion channel inhibitor activity
GO:0030292--F:protein tyrosine kinase inhibitor activity
GO:0003723--F:RNA binding
GO:0035591--F:signaling adaptor activity
GO:0071333--P:cellular response to glucose stimulus
GO:0071363--P:cellular response to growth factor stimulus
GO:0030308--P:negative regulation of cell growth
GO:0010629--P:negative regulation of gene expression
GO:1903208--P:negative regulation of hydrogen peroxide-induced neuron death
GO:0033137--P:negative regulation of peptidyl-serine phosphorylation
GO:0050765--P:negative regulation of phagocytosis
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0043473--P:pigmentation
GO:0030822--P:positive regulation of cAMP catabolic process
GO:0030335--P:positive regulation of cell migration
GO:0051343--P:positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0042998--P:positive regulation of Golgi to plasma membrane protein transport
GO:0043547--P:positive regulation of GTPase activity
GO:2001244--P:positive regulation of intrinsic apoptotic signaling pathway
GO:0051901--P:positive regulation of mitochondrial depolarization
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032464--P:positive regulation of protein homooligomerization
GO:0001934--P:positive regulation of protein phosphorylation
GO:0051726--P:regulation of cell cycle
GO:0006412--P:translation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000395	Aegilops tauschii	62.32	1.00e-100	358.00
IUUC-Aml-001935	Ailuropoda melanoleuca	95.58	1.00e-180	624.00
IUUC-Atr-002694	Amborella trichopoda	65.50	9.00e-122	429.00
IUUC-Apl-003918	Anas platyrhynchos	99.64	5.00e-166	575.00
IUUC-Aca-004869	Anolis carolinensis	95.58	1.00e-180	624.00
IUUC-Aly-005671	Arabidopsis lyrata	62.96	3.00e-121	427.00
IUUC-Ath-007105	Arabidopsis thaliana	63.78	1.00e-121	429.00
IUUC-Ago-007720	Ashbya gossypii	54.95	7.00e-99	353.00
IUUC-Acl-008156	Aspergillus clavatus	71.15	5.00e-135	473.00
IUUC-Afl-008684	Aspergillus flavus	70.19	9.00e-134	469.00
IUUC-Afu-008867	Aspergillus fumigatus	72.12	2.00e-136	478.00
IUUC-Ani-009221	Aspergillus nidulans	71.15	4.00e-135	473.00
IUUC-Ang-009843	Aspergillus niger	70.19	3.00e-133	467.00
IUUC-Aor-010193	Aspergillus oryzae	70.19	9.00e-134	469.00
IUUC-Ate-010420	Aspergillus terreus	71.38	1.00e-122	431.00
IUUC-Ame-010884	Astyanax mexicanus	92.11	6.00e-177	612.00
IUUC-Bgr-012064	Blumeria graminis	68.27	8.00e-131	459.00
IUUC-Bta-013357	Bos taurus	95.58	1.00e-180	624.00
IUUC-Bci-013862	Botrytis cinerea	69.87	4.00e-134	470.00
IUUC-Bdi-014690	Brachypodium distachyon	61.16	8.00e-113	399.00
IUUC-Bol-016231	Brassica oleracea	64.40	2.00e-123	435.00
IUUC-Bra-016879	Brassica rapa	63.98	5.00e-122	430.00
IUUC-Cel-018335	Caenorhabditis elegans	67.19	3.00e-121	427.00
IUUC-Cja-019914	Callithrix jacchus	95.58	1.00e-180	624.00
IUUC-Cfa-020755	Canis familiaris	95.58	1.00e-180	624.00
IUUC-Cpo-022377	Cavia porcellus	95.58	0.00e+00	625.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	72.29	6.00e-134	469.00
IUUC-Csa-023025	Chlorocebus sabaeus	95.58	2.00e-180	624.00
IUUC-Cin-025647	Ciona intestinalis	73.57	9.00e-140	489.00
IUUC-Csv-026027	Ciona savignyi	74.20	2.00e-139	488.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	73.50	6.00e-127	446.00
IUUC-Cne-026930	Cryptococcus neoformans	68.27	4.00e-132	463.00
IUUC-Cme-027251	Cyanidioschyzon merolae	61.86	1.00e-118	418.00
IUUC-Dre-028669	Danio rerio	91.17	1.00e-175	608.00
IUUC-Dno-029470	Dasypus novemcinctus	80.13	1.00e-140	492.00
IUUC-Dor-031098	Dipodomys ordii	85.49	1.00e-140	492.00
IUUC-Dse-031255	Dothistroma septosporum	69.87	1.00e-133	469.00
IUUC-Dme-032118	Drosophila melanogaster	73.97	1.00e-141	495.00
IUUC-Ete-033182	Echinops telfairi	82.96	6.00e-105	373.00
IUUC-Eca-033296	Equus caballus	99.33	7.00e-87	311.00
IUUC-Eeu-034771	Erinaceus europaeus	90.54	2.00e-168	584.00
IUUC-Fca-036315	Felis catus	95.58	1.00e-180	624.00
IUUC-Fal-036990	Ficedula albicollis	96.67	9.00e-103	366.00
IUUC-Fox-037702	Fusarium oxysporum	70.83	7.00e-136	476.00
IUUC-Fso-038384	Fusarium solani	71.79	2.00e-136	478.00
IUUC-Gmo-039630	Gadus morhua	89.61	5.00e-168	582.00
IUUC-Ggr-039985	Gaeumannomyces graminis	71.47	2.00e-136	478.00
IUUC-Gga-040540	Gallus gallus	95.58	1.00e-180	624.00
IUUC-Gac-041316	Gasterosteus aculeatus	87.14	6.00e-166	576.00
IUUC-Gma-042872	Glycine max	63.66	1.00e-121	429.00
IUUC-Ggo-045253	Gorilla gorilla	95.58	1.00e-180	624.00
IUUC-Hsa-046809	Homo sapiens	95.58	1.00e-180	624.00
IUUC-Hvu-047683	Hordeum vulgare	62.01	4.00e-114	404.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	95.58	1.00e-180	624.00
IUUC-Kpa-049214	Komagataella pastoris	56.13	5.00e-95	340.00
IUUC-Lch-049634	Latimeria chalumnae	89.91	4.00e-173	599.00
IUUC-Lpe-050763	Leersia perrieri	61.16	1.00e-112	399.00
IUUC-Loc-052163	Lepisosteus oculatus	92.74	8.00e-178	615.00
IUUC-Lma-053113	Leptosphaeria maculans	71.47	7.00e-136	476.00
IUUC-Laf-054422	Loxodonta africana	95.58	1.00e-180	624.00
IUUC-Mcc-055348	Macaca mulatta	95.58	2.00e-180	624.00
IUUC-Meu-056543	Macropus eugenii	95.58	0.00e+00	626.00
IUUC-Mor-057107	Magnaporthe oryzae	71.47	5.00e-137	479.00
IUUC-Mpo-057487	Magnaporthe poae	71.79	7.00e-137	479.00
IUUC-Mtr-058808	Medicago truncatula	63.98	4.00e-122	430.00
IUUC-Mla-058909	Melampsora laricipopulina	70.61	1.00e-134	472.00
IUUC-Mga-059387	Meleagris gallopavo	95.58	1.00e-180	624.00
IUUC-Mvi-060392	Microbotryum violaceum	66.35	3.00e-129	454.00
IUUC-Mmr-061141	Microcebus murinus	87.54	1.00e-136	478.00
IUUC-Mdo-062932	Monodelphis domestica	95.58	1.00e-180	624.00
IUUC-Mmu-064132	Mus musculus	95.58	1.00e-180	624.00
IUUC-Mac-064447	Musa acuminata	59.57	9.00e-107	379.00
IUUC-Mpu-066721	Mustela putorius furo	94.64	4.00e-177	613.00
IUUC-Mlu-068221	Myotis lucifugus	94.95	2.00e-168	584.00
IUUC-Nfi-068344	Neosartorya fischeri	72.12	2.00e-136	478.00
IUUC-Ncr-068722	Neurospora crassa	70.19	5.00e-134	469.00
IUUC-Nle-069865	Nomascus leucogenys	95.58	1.00e-180	625.00
IUUC-Opr-071100	Ochotona princeps	80.44	2.00e-143	501.00
IUUC-Ont-072287	Oreochromis niloticus	90.22	2.00e-174	604.00
IUUC-Oan-072788	Ornithorhynchus anatinus	95.58	1.00e-180	624.00
IUUC-Ocu-073844	Oryctolagus cuniculus	93.06	1.00e-173	602.00
IUUC-Oba-075652	Oryza barthii	58.38	3.00e-105	374.00
IUUC-Obr-076099	Oryza brachyantha	60.55	2.00e-112	398.00
IUUC-Ogl-077804	Oryza glaberrima	61.47	2.00e-114	404.00
IUUC-Ogu-078035	Oryza glumaepatula	61.54	1.00e-112	399.00
IUUC-Oin-079327	Oryza indica	61.54	1.00e-112	399.00
IUUC-Olo-081084	Oryza longistaminata	61.54	1.00e-112	399.00
IUUC-Ome-081366	Oryza meridionalis	61.77	1.00e-114	405.00
IUUC-Oni-082682	Oryza nivara	61.77	1.00e-114	405.00
IUUC-Opu-084010	Oryza punctata	61.77	4.00e-115	407.00
IUUC-Oru-084358	Oryza rufipogon	61.77	1.00e-114	405.00
IUUC-Osa-085296	Oryza sativa	61.77	1.00e-114	405.00
IUUC-Ola-086400	Oryzias latipes	89.91	5.00e-174	602.00
IUUC-Olu-087817	Ostreococcus lucimarinus	73.90	1.00e-139	488.00
IUUC-Oga-088811	Otolemur garnettii	95.58	1.00e-180	624.00
IUUC-Oar-089962	Ovis aries	95.58	1.00e-180	624.00
IUUC-Ptr-091340	Pan troglodytes	95.58	1.00e-180	624.00
IUUC-Pan-091946	Papio anubis	95.58	2.00e-180	624.00
IUUC-Pma-094535	Petromyzon marinus	89.59	1.00e-172	598.00
IUUC-Pno-095100	Phaeosphaeria nodorum	73.11	2.00e-93	334.00
IUUC-Ppa-095588	Physcomitrella patens	73.16	3.00e-136	477.00
IUUC-Pfo-097311	Poecilia formosa	89.91	5.00e-174	602.00
IUUC-Pab-097863	Pongo abelii	95.58	1.00e-180	625.00
IUUC-Pop-099345	Populus trichocarpa	65.02	1.00e-124	439.00
IUUC-Pca-100594	Procavia capensis	94.64	8.00e-179	619.00
IUUC-Ppe-101743	Prunus persica	62.96	2.00e-120	424.00
IUUC-Pva-102746	Pteropus vampyrus	79.50	7.00e-142	496.00
IUUC-Pgr-103375	Puccinia graminis	54.95	8.00e-93	332.00
IUUC-Ptt-103839	Puccinia triticina	70.61	3.00e-133	467.00
IUUC-Pte-104026	Pyrenophora teres	71.47	7.00e-136	476.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	71.47	8.00e-136	476.00
IUUC-Rno-104964	Rattus norvegicus	95.58	1.00e-180	624.00
IUUC-Sce-106224	Saccharomyces cerevisiae	52.87	1.00e-94	338.00
IUUC-Sha-107409	Sarcophilus harrisii	95.58	1.00e-180	624.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	64.86	2.00e-122	431.00
IUUC-Spo-108297	Schizosaccharomyces pombe	63.26	3.00e-119	421.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	69.87	4.00e-134	470.00
IUUC-Smo-109017	Selaginella moellendorffii	67.09	5.00e-125	440.00
IUUC-Sit-110060	Setaria italica	62.15	4.00e-115	407.00
IUUC-Sly-111496	Solanum lycopersicum	65.94	4.00e-123	434.00
IUUC-Stu-112757	Solanum tuberosum	64.38	5.00e-119	420.00
IUUC-Sar-113173	Sorex araneus	95.58	1.00e-180	624.00
IUUC-Sbi-114681	Sorghum bicolor	61.23	6.00e-113	400.00
IUUC-Sre-115107	Sporisorium reilianum	69.23	1.00e-134	472.00
IUUC-Tru-118202	Takifugu rubripes	88.64	2.00e-171	594.00
IUUC-Tni-120260	Tetraodon nigroviridis	88.33	7.00e-171	592.00
IUUC-Tca-120951	Theobroma cacao	63.66	3.00e-123	434.00
IUUC-Tre-121961	Trichoderma reesei	72.12	2.00e-137	481.00
IUUC-Tvi-122447	Trichoderma virens	71.79	2.00e-136	477.00
IUUC-Tae-123560	Triticum aestivum	61.40	3.00e-113	400.00
IUUC-Tur-126335	Triticum urartu	67.41	9.00e-104	369.00
IUUC-Tme-127105	Tuber melanosporum	66.67	7.00e-123	432.00
IUUC-Tbe-128021	Tupaia belangeri	79.70	3.00e-86	310.00
IUUC-Ttr-128637	Tursiops truncatus	83.91	2.00e-153	534.00
IUUC-Uma-129634	Ustilago maydis	69.87	2.00e-135	474.00
IUUC-Vda-129923	Verticillium dahliae	71.15	9.00e-136	475.00
IUUC-Vpa-130410	Vicugna pacos	72.20	3.00e-103	367.00
IUUC-Vvi-131115	Vitis vinifera	64.20	2.00e-123	434.00
IUUC-Xtr-132105	Xenopus tropicalis	92.11	2.00e-177	613.00
IUUC-Xma-133875	Xiphophorus maculatus	90.22	3.00e-174	603.00
IUUC-Yli-134624	Yarrowia lipolytica	59.18	1.00e-115	409.00
IUUC-Zma-134711	Zea mays	61.23	6.00e-113	400.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence