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Tag Content
UUCD2 ID IUUC-Fca-035833
UUCD1 version UUC-FeC-00545
Ensembl Protein ID ENSFCAP00000003658.2
UniProt Accession M3W1A8; M3W1A8_FELCA
Genbank Protein ID ENSFCAP00000003658
Protein Name tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4
Genbank Nucleotide ID AANG02044566
Gene Name WDR4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000003966.2 ENSFCAT00000003967.2 ENSFCAP00000003658.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.70e-06 27.1 166 205
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ + f  +d   ll+s+s+D t+++W++r+g+ l+
   Q: 166  GHTEFVSRI-FvvPDhpELLLSASGDRTLRLWEYRSGRELH 205
           677777777.799777899******************9876 PP
   
Organism Felis catus
Functional Description
(View)

Functional Description


     Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
 Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Protein Sequence
(Fasta)
FLKSLFFLSD DDVLFAYDCS TAAEKSQESK GEDGQPADKG SDTVLASTFS KSGTYFALTD 60
DSKRLILFRT KPWQCLSVRT VVRRCTALTF TASEEKLLVA DKSGDVYSFS VLEPQGCGKL 120
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Protein Fasta Sequence


>IUUC-Fca-035833|E3,WD_repeat|Felis catus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTTTAAAAT CTTTGTTCTT CCTTAGTGAT GATGACGTCC TCTTCGCATA TGATTGCAGC 60
ACGGCAGCAG AGAAGTCACA AGAAAGTAAA GGGTGAGGTA ATGGGGGGGC CTCATCGGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fca-035833|E3,WD_repeat|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat
Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0043527--C:tRNA methyltransferase complex
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000556 Aegilops tauschii 26.96 1.00e-12 67.40
IUUC-Apl-003975 Anas platyrhynchos 58.31 2.00e-126 445.00
IUUC-Aca-005170 Anolis carolinensis 54.21 3.00e-107 381.00
IUUC-Aly-005769 Arabidopsis lyrata 29.41 5.00e-22 99.00
IUUC-Ath-006733 Arabidopsis thaliana 33.84 1.00e-21 97.80
IUUC-Acl-008151 Aspergillus clavatus 36.84 4.00e-15 75.90
IUUC-Afl-008518 Aspergillus flavus 44.00 1.00e-15 77.00
IUUC-Afu-009102 Aspergillus fumigatus 31.02 2.00e-15 77.40
IUUC-Ani-009442 Aspergillus nidulans 31.44 4.00e-18 85.90
IUUC-Aor-010133 Aspergillus oryzae 31.27 2.00e-18 87.00
IUUC-Ate-010465 Aspergillus terreus 41.84 1.00e-14 74.70
IUUC-Ame-010613 Astyanax mexicanus 45.81 2.00e-85 309.00
IUUC-Bgr-012067 Blumeria graminis 34.44 2.00e-18 87.40
IUUC-Bta-012788 Bos taurus 78.85 5.00e-171 593.00
IUUC-Bdi-014458 Brachypodium distachyon 30.65 6.00e-18 85.10
IUUC-Bol-016398 Brassica oleracea 38.59 1.00e-23 104.00
IUUC-Bra-016644 Brassica rapa 38.46 1.00e-23 105.00
IUUC-Cpo-021963 Cavia porcellus 75.63 8.00e-154 536.00
IUUC-Csa-024148 Chlorocebus sabaeus 74.67 1.00e-148 519.00
IUUC-Cne-026834 Cryptococcus neoformans 35.62 1.00e-18 88.20
IUUC-Dre-028427 Danio rerio 45.58 5.00e-88 317.00
IUUC-Dno-028881 Dasypus novemcinctus 65.82 4.00e-144 504.00
IUUC-Dor-030522 Dipodomys ordii 71.86 3.00e-152 531.00
IUUC-Dme-032136 Drosophila melanogaster 36.31 4.00e-24 105.00
IUUC-Fal-037497 Ficedula albicollis 60.42 6.00e-123 433.00
IUUC-Gga-040547 Gallus gallus 57.67 4.00e-129 454.00
IUUC-Gac-041761 Gasterosteus aculeatus 47.52 2.00e-78 285.00
IUUC-Gma-043722 Glycine max 35.00 3.00e-18 86.30
IUUC-Ggo-045340 Gorilla gorilla 73.21 3.00e-159 554.00
IUUC-Hsa-046403 Homo sapiens 72.96 2.00e-158 551.00
IUUC-Hvu-047643 Hordeum vulgare 30.61 7.00e-19 88.20
IUUC-Itr-048103 Ictidomys tridecemlineatus 76.09 2.00e-157 548.00
IUUC-Kpa-049283 Komagataella pastoris 30.35 3.00e-20 92.80
IUUC-Lch-050682 Latimeria chalumnae 52.73 2.00e-111 395.00
IUUC-Lpe-050712 Leersia perrieri 32.79 2.00e-25 110.00
IUUC-Loc-052599 Lepisosteus oculatus 52.57 4.00e-110 391.00
IUUC-Laf-054390 Loxodonta africana 74.49 5.00e-169 587.00
IUUC-Mcc-054747 Macaca mulatta 73.88 6.00e-155 540.00
IUUC-Mtr-058600 Medicago truncatula 37.43 8.00e-23 101.00
IUUC-Mla-059129 Melampsora laricipopulina 26.04 3.00e-12 65.90
IUUC-Mga-059876 Meleagris gallopavo 57.14 6.00e-128 450.00
IUUC-Mvi-060359 Microbotryum violaceum 30.54 3.00e-12 66.60
IUUC-Mmr-061518 Microcebus murinus 72.45 3.00e-164 570.00
IUUC-Mac-065625 Musa acuminata 32.98 2.00e-18 86.70
IUUC-Nfi-068402 Neosartorya fischeri 28.81 1.00e-14 74.70
IUUC-Nle-069914 Nomascus leucogenys 74.67 4.00e-153 534.00
IUUC-Ont-071555 Oreochromis niloticus 44.19 1.00e-74 273.00
IUUC-Oan-072951 Ornithorhynchus anatinus 67.45 4.00e-148 517.00
IUUC-Ocu-074679 Oryctolagus cuniculus 77.49 2.00e-156 544.00
IUUC-Oba-075355 Oryza barthii 25.00 6.00e-11 62.40
IUUC-Obr-076769 Oryza brachyantha 31.17 2.00e-23 103.00
IUUC-Ogl-077168 Oryza glaberrima 30.40 8.00e-24 104.00
IUUC-Ogu-078275 Oryza glumaepatula 25.68 4.00e-11 62.80
IUUC-Oin-079207 Oryza indica 30.40 8.00e-24 104.00
IUUC-Oni-082437 Oryza nivara 26.89 1.00e-10 61.20
IUUC-Opu-084031 Oryza punctata 30.71 5.00e-22 99.00
IUUC-Oru-084380 Oryza rufipogon 26.36 9.00e-11 61.60
IUUC-Osa-085327 Oryza sativa 30.40 2.00e-23 103.00
IUUC-Ola-086716 Oryzias latipes 43.58 1.00e-69 256.00
IUUC-Olu-087708 Ostreococcus lucimarinus 28.34 9.00e-14 71.20
IUUC-Oar-090239 Ovis aries 82.16 6.00e-167 580.00
IUUC-Ptr-090851 Pan troglodytes 73.21 2.00e-159 554.00
IUUC-Pan-092558 Papio anubis 73.75 4.00e-147 514.00
IUUC-Psi-093792 Pelodiscus sinensis 61.08 3.00e-131 461.00
IUUC-Ppa-095757 Physcomitrella patens 35.91 2.00e-20 94.00
IUUC-Pfo-096465 Poecilia formosa 44.79 2.00e-82 298.00
IUUC-Pab-097722 Pongo abelii 75.73 5.00e-162 563.00
IUUC-Pop-098979 Populus trichocarpa 33.33 3.00e-20 92.80
IUUC-Pca-100753 Procavia capensis 72.32 5.00e-119 420.00
IUUC-Ppe-101515 Prunus persica 29.44 7.00e-18 85.10
IUUC-Sja-107780 Schizosaccharomyces japonicus 28.02 8.00e-13 68.20
IUUC-Spo-108251 Schizosaccharomyces pombe 27.51 2.00e-12 66.60
IUUC-Smo-108938 Selaginella moellendorffii 37.91 1.00e-22 100.00
IUUC-Sit-110020 Setaria italica 29.55 9.00e-22 97.80
IUUC-Sly-111543 Solanum lycopersicum 29.11 3.00e-21 96.30
IUUC-Stu-111925 Solanum tuberosum 28.27 2.00e-21 96.70
IUUC-Sbi-114061 Sorghum bicolor 30.28 5.00e-21 95.10
IUUC-Tgu-117321 Taeniopygia guttata 59.06 4.00e-113 400.00
IUUC-Tru-118454 Takifugu rubripes 46.80 6.00e-77 280.00
IUUC-Tni-119894 Tetraodon nigroviridis 45.01 8.00e-74 270.00
IUUC-Tca-121746 Theobroma cacao 33.16 2.00e-19 90.50
IUUC-Tae-123054 Triticum aestivum 30.49 1.00e-19 90.90
IUUC-Tur-126254 Triticum urartu 27.16 3.00e-14 72.80
IUUC-Tbe-127683 Tupaia belangeri 45.45 4.00e-46 178.00
IUUC-Ttr-129056 Tursiops truncatus 74.07 8.00e-160 556.00
IUUC-Vvi-131428 Vitis vinifera 34.41 5.00e-21 95.50
IUUC-Xma-133605 Xiphophorus maculatus 43.92 4.00e-82 298.00
Created Date 25-Jun-2017

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