iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-065301

Ensembl Protein ID

GSMUA_Achr3P00030_001

UniProt Accession

M0SAH1; M0SAH1_MUSAM

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr3G00030_001	GSMUA_Achr3T00030_001	GSMUA_Achr3P00030_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	4.60e-78	263.8	2	303

Active Site

Position(s)	Description	Evidence
82	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
157	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           +w+++esdPg+ft+l+++  vk++ qveelysLd + l+ + +pv+gl++lFk+   ++  r           v +d   ++ffa qv
   Q: 2    SWCTIESDPGVFTELIQQMQVKGV-QVEELYSLDLDFLDNL-RPVYGLIFLFKWRRGEKDDR----------PVIKDPNPNLFFASQV 77
           7***********************.****************.************99988888..........23367788******** PP
   S: 95   igNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvs 182
           i+N+Cat+A+ls l nc d   d+G++ls lke+tk + pe k+la++n+++++ +hns+ar+e++  +e++    + ++++++hf+s
   Q: 78   INNACATQAILSILVNCPDI--DIGPELSMLKEFTKNFPPELKGLAINNSEAIRTAHNSFARPEPFVPEEQK---VAGKDDDVYHFIS 160
           *******************9..********************************************988777...44569******** PP
   S: 183  yvningrlyeldglkpfPldlgkk...keteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkidkeLlkLlk 267
           y +++g lyeldglk+ P+ lg++     + ++ + ++ v+   eri+ +++ eirfnl+ai ++r+ i+t+ l+ l+ ++e l+L +
   Q: 161  YLPVDGVLYELDGLKEGPISLGQCpggPGDLDWLQMVQPVI--QERIDRYSQSEIRFNLMAIIKNRKEIYTAELKELQKQREHLSL-T 245
           ***********************976557889*********..*****************************************97.6 PP
   S: 268  dieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveet 325
           ++ + +e  ++++  e+ek kk+  ++irR++ny  f++ f+k la++++l+ l e+ 
   Q: 246  EVTASIESVSEKILMEEEKFKKWRTENIRRKHNYIPFLFNFLKILAEKKQLKPLIEKA 303
           789999999999999**************************************99984 PP

Organism

Musa acuminata

Protein Sequence
(Fasta)

MSWCTIESDP GVFTELIQQM QVKGVQVEEL YSLDLDFLDN LRPVYGLIFL FKWRRGEKDD 60
RPVIKDPNPN LFFASQVINN ACATQAILSI LVNCPDIDIG PELSMLKEFT KNFPPELKGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATTTCTCA GGATGTCTTG GTGTACTATT GAGTCTGATC CTGGTAAGTC ATTGATATGA 60
AGTGAATTTT TGCTGCTAAA ACTATTTTTC ATGACATCTT TCTCATGCAT ATGTCTTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0010016--P:shoot system morphogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	73.62	4.00e-141	493.00
IUUC-Aml-001866	Ailuropoda melanoleuca	50.48	2.00e-85	308.00
IUUC-Atr-002966	Amborella trichopoda	77.11	9.00e-141	492.00
IUUC-Apl-003306	Anas platyrhynchos	46.61	1.00e-79	289.00
IUUC-Aca-004763	Anolis carolinensis	50.80	4.00e-85	307.00
IUUC-Aly-005581	Arabidopsis lyrata	76.23	8.00e-136	475.00
IUUC-Ath-007283	Arabidopsis thaliana	75.31	2.00e-138	484.00
IUUC-Ago-007999	Ashbya gossypii	37.40	9.00e-32	130.00
IUUC-Acl-008231	Aspergillus clavatus	52.08	2.00e-61	228.00
IUUC-Afl-008557	Aspergillus flavus	45.48	1.00e-61	228.00
IUUC-Afu-008988	Aspergillus fumigatus	51.90	2.00e-61	228.00
IUUC-Ani-009420	Aspergillus nidulans	43.65	7.00e-64	236.00
IUUC-Ang-009859	Aspergillus niger	49.79	9.00e-58	216.00
IUUC-Aor-010145	Aspergillus oryzae	45.48	1.00e-61	228.00
IUUC-Ate-010347	Aspergillus terreus	48.44	1.00e-59	222.00
IUUC-Ame-010791	Astyanax mexicanus	51.56	3.00e-88	317.00
IUUC-Bgr-012298	Blumeria graminis	41.98	2.00e-59	221.00
IUUC-Bta-013251	Bos taurus	50.65	2.00e-86	311.00
IUUC-Bci-013786	Botrytis cinerea	42.28	8.00e-63	233.00
IUUC-Bdi-014132	Brachypodium distachyon	77.88	6.00e-139	486.00
IUUC-Bol-015611	Brassica oleracea	78.33	5.00e-142	496.00
IUUC-Bra-017769	Brassica rapa	78.95	1.00e-142	498.00
IUUC-Cel-018604	Caenorhabditis elegans	44.34	8.00e-71	259.00
IUUC-Cja-019768	Callithrix jacchus	45.43	4.00e-80	290.00
IUUC-Cfa-020207	Canis familiaris	50.48	2.00e-85	308.00
IUUC-Cpo-021925	Cavia porcellus	48.23	2.00e-79	288.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	49.54	5.00e-84	303.00
IUUC-Csa-023958	Chlorocebus sabaeus	50.00	1.00e-85	309.00
IUUC-Cho-024928	Choloepus hoffmanni	55.41	2.00e-18	85.50
IUUC-Cin-025771	Ciona intestinalis	41.61	1.00e-68	252.00
IUUC-Csv-026149	Ciona savignyi	44.24	4.00e-72	264.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	38.74	2.00e-50	191.00
IUUC-Cne-026955	Cryptococcus neoformans	33.33	3.00e-45	174.00
IUUC-Cme-027104	Cyanidioschyzon merolae	33.33	4.00e-45	174.00
IUUC-Dre-027409	Danio rerio	50.79	9.00e-88	316.00
IUUC-Dno-028921	Dasypus novemcinctus	50.48	3.00e-85	307.00
IUUC-Dor-030891	Dipodomys ordii	46.78	5.00e-36	145.00
IUUC-Dse-031170	Dothistroma septosporum	40.12	1.00e-60	226.00
IUUC-Dme-031677	Drosophila melanogaster	50.65	7.00e-83	299.00
IUUC-Ete-032646	Echinops telfairi	46.05	2.00e-43	169.00
IUUC-Eca-033776	Equus caballus	49.48	9.00e-77	279.00
IUUC-Eeu-035305	Erinaceus europaeus	44.51	7.00e-39	153.00
IUUC-Fca-035846	Felis catus	46.45	1.00e-80	293.00
IUUC-Fal-037597	Ficedula albicollis	50.52	1.00e-74	272.00
IUUC-Fox-037670	Fusarium oxysporum	40.33	4.00e-54	204.00
IUUC-Fso-038243	Fusarium solani	40.98	2.00e-53	202.00
IUUC-Gmo-038499	Gadus morhua	47.27	2.00e-78	285.00
IUUC-Ggr-039975	Gaeumannomyces graminis	45.68	4.00e-52	197.00
IUUC-Gga-040904	Gallus gallus	52.05	2.00e-89	321.00
IUUC-Gac-042058	Gasterosteus aculeatus	50.80	1.00e-86	311.00
IUUC-Gma-043030	Glycine max	83.48	1.00e-156	545.00
IUUC-Ggo-044699	Gorilla gorilla	46.20	6.00e-74	270.00
IUUC-Hsa-046227	Homo sapiens	49.84	1.00e-85	309.00
IUUC-Hvu-047359	Hordeum vulgare	74.46	7.00e-140	489.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	45.61	1.00e-80	292.00
IUUC-Lch-049829	Latimeria chalumnae	51.45	1.00e-86	312.00
IUUC-Lpe-050899	Leersia perrieri	78.55	1.00e-137	481.00
IUUC-Loc-052264	Lepisosteus oculatus	50.00	9.00e-84	302.00
IUUC-Lma-053110	Leptosphaeria maculans	43.14	8.00e-55	206.00
IUUC-Laf-053639	Loxodonta africana	50.48	2.00e-85	308.00
IUUC-Mcc-055506	Macaca mulatta	50.00	1.00e-85	309.00
IUUC-Meu-056267	Macropus eugenii	44.71	1.00e-49	190.00
IUUC-Mor-057001	Magnaporthe oryzae	47.13	8.00e-56	209.00
IUUC-Mpo-057608	Magnaporthe poae	46.15	4.00e-36	143.00
IUUC-Mtr-057731	Medicago truncatula	80.61	2.00e-148	518.00
IUUC-Mla-059016	Melampsora laricipopulina	46.00	8.00e-45	172.00
IUUC-Mga-060178	Meleagris gallopavo	50.17	4.00e-80	290.00
IUUC-Mvi-060353	Microbotryum violaceum	41.10	2.00e-56	211.00
IUUC-Mmr-060738	Microcebus murinus	50.16	6.00e-86	310.00
IUUC-Mdo-062266	Monodelphis domestica	52.88	4.00e-61	226.00
IUUC-Mmu-063619	Mus musculus	50.48	2.00e-85	308.00
IUUC-Mpu-066058	Mustela putorius furo	49.84	1.00e-85	308.00
IUUC-Mlu-067292	Myotis lucifugus	50.48	3.00e-85	307.00
IUUC-Nfi-068275	Neosartorya fischeri	43.64	5.00e-64	237.00
IUUC-Ncr-068713	Neurospora crassa	42.63	2.00e-61	228.00
IUUC-Nle-069013	Nomascus leucogenys	50.00	5.00e-86	310.00
IUUC-Opr-070628	Ochotona princeps	43.62	2.00e-74	271.00
IUUC-Ont-072688	Oreochromis niloticus	50.00	5.00e-85	306.00
IUUC-Oan-073004	Ornithorhynchus anatinus	52.73	6.00e-65	239.00
IUUC-Ocu-074303	Oryctolagus cuniculus	49.84	2.00e-85	309.00
IUUC-Oba-075002	Oryza barthii	79.75	4.00e-143	499.00
IUUC-Obr-076392	Oryza brachyantha	79.11	2.00e-139	488.00
IUUC-Ogl-077271	Oryza glaberrima	79.75	4.00e-143	499.00
IUUC-Ogu-078493	Oryza glumaepatula	80.06	2.00e-144	504.00
IUUC-Oin-080084	Oryza indica	80.06	2.00e-144	504.00
IUUC-Olo-080803	Oryza longistaminata	79.75	7.00e-144	502.00
IUUC-Ome-081146	Oryza meridionalis	79.44	5.00e-143	499.00
IUUC-Oni-082146	Oryza nivara	80.06	2.00e-144	504.00
IUUC-Opu-083633	Oryza punctata	79.75	3.00e-140	490.00
IUUC-Oru-084789	Oryza rufipogon	80.06	2.00e-144	504.00
IUUC-Osa-086196	Oryza sativa	80.06	2.00e-144	504.00
IUUC-Ola-087126	Oryzias latipes	50.48	1.00e-85	308.00
IUUC-Olu-087665	Ostreococcus lucimarinus	48.94	1.00e-74	272.00
IUUC-Oga-089140	Otolemur garnettii	46.15	4.00e-81	294.00
IUUC-Oar-090296	Ovis aries	50.00	1.00e-84	305.00
IUUC-Ptr-090566	Pan troglodytes	49.84	1.00e-85	309.00
IUUC-Pan-092052	Papio anubis	50.00	1.00e-85	309.00
IUUC-Psi-093723	Pelodiscus sinensis	49.83	2.00e-77	281.00
IUUC-Pma-094568	Petromyzon marinus	41.96	2.00e-62	231.00
IUUC-Pno-095120	Phaeosphaeria nodorum	41.38	1.00e-56	212.00
IUUC-Ppa-095761	Physcomitrella patens	72.22	1.00e-137	481.00
IUUC-Pfo-096210	Poecilia formosa	50.48	4.00e-86	310.00
IUUC-Pab-098463	Pongo abelii	49.84	1.00e-85	309.00
IUUC-Pop-099109	Populus trichocarpa	81.21	2.00e-151	528.00
IUUC-Pca-100108	Procavia capensis	52.70	4.00e-70	257.00
IUUC-Ppe-101176	Prunus persica	83.48	3.00e-155	540.00
IUUC-Pva-102629	Pteropus vampyrus	53.56	1.00e-72	265.00
IUUC-Pgr-103419	Puccinia graminis	41.21	7.00e-56	209.00
IUUC-Pte-104207	Pyrenophora teres	52.12	7.00e-39	152.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	42.63	2.00e-60	224.00
IUUC-Rno-105579	Rattus norvegicus	44.31	9.00e-74	269.00
IUUC-Sha-106894	Sarcophilus harrisii	50.36	3.00e-74	270.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	45.70	2.00e-65	242.00
IUUC-Spo-108371	Schizosaccharomyces pombe	46.15	8.00e-72	263.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	41.79	8.00e-52	196.00
IUUC-Smo-109396	Selaginella moellendorffii	74.46	2.00e-134	471.00
IUUC-Sit-110630	Setaria italica	77.61	6.00e-140	489.00
IUUC-Sly-110972	Solanum lycopersicum	81.21	1.00e-149	521.00
IUUC-Stu-112185	Solanum tuberosum	82.28	6.00e-162	562.00
IUUC-Sar-113294	Sorex araneus	42.94	4.00e-71	261.00
IUUC-Sbi-113951	Sorghum bicolor	76.69	1.00e-136	478.00
IUUC-Ssc-115501	Sus scrofa	48.34	7.00e-79	286.00
IUUC-Tgu-117152	Taeniopygia guttata	50.52	1.00e-74	272.00
IUUC-Tru-118388	Takifugu rubripes	50.48	2.00e-86	311.00
IUUC-Tsy-119109	Tarsius syrichta	49.84	9.00e-86	309.00
IUUC-Tni-120048	Tetraodon nigroviridis	50.48	1.00e-86	312.00
IUUC-Tca-121750	Theobroma cacao	82.78	2.00e-161	560.00
IUUC-Tre-122130	Trichoderma reesei	41.30	6.00e-55	206.00
IUUC-Tvi-122284	Trichoderma virens	42.56	2.00e-55	208.00
IUUC-Tae-124082	Triticum aestivum	74.77	2.00e-141	494.00
IUUC-Tur-126366	Triticum urartu	67.19	3.00e-108	384.00
IUUC-Tme-127187	Tuber melanosporum	43.22	5.00e-70	257.00
IUUC-Tbe-127619	Tupaia belangeri	43.99	3.00e-58	217.00
IUUC-Ttr-128867	Tursiops truncatus	46.56	3.00e-59	221.00
IUUC-Vda-129912	Verticillium dahliae	41.05	8.00e-56	209.00
IUUC-Vpa-130552	Vicugna pacos	52.91	2.00e-60	225.00
IUUC-Vvi-130881	Vitis vinifera	84.94	6.00e-159	552.00
IUUC-Xtr-131934	Xenopus tropicalis	49.84	3.00e-86	310.00
IUUC-Xma-133312	Xiphophorus maculatus	50.48	4.00e-86	310.00
IUUC-Yli-134487	Yarrowia lipolytica	35.19	1.00e-53	202.00
IUUC-Zma-135462	Zea mays	66.46	6.00e-115	406.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence