iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009254

Ensembl Protein ID

CADANIAP00002619

UniProt Accession

Q5BH53; C8VQJ6; ATG18_EMENI

Genbank Protein ID

EAA65305.1; CBF90145.1

Protein Name

Autophagy-related protein 18

Genbank Nucleotide ID

AACD01000004; BN001308

Gene Name

ANIA_00127; atg18; AN0127

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00002619	CADANIAT00002619	CADANIAP00002619

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-08	33.7	186	223

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgt.ikvWDlrtgvll 36
           H ++  c+ + sd tl++++sd gt i+v+++ +g++l
   Q: 186  HRSPLACITLnSDgTLIATASDKGTiIRVFSVPDGHKL 223
           999********999***********999****999876 PP

Organism

Aspergillus nidulans

Functional Description
(View)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

Protein Sequence
(Fasta)

MTMNFVTFNQ DYSYLAVATS KGFRIFTTDP FAKSYETKDG NIAIIEMLFS TSLVALILSP 60
RRLQITNTKR QSTICELTFP TTVLAVKLNR KRLVIVLEDQ IYLYDIQTMK LLYTIETSPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGATGA ACTTTGTGAC ATTCAACCAG GACTATAGCT ACCTGGCTGT AGGTAAGGCA 60
TTCTCGTATG GCTTGTACTC GTTATGAAAC CCCGCTTGAC ACCCGCTAGC GACCTCCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0010008--C:endosome membrane
GO:0000329--C:fungal-type vacuole membrane
GO:0005794--C:Golgi apparatus
GO:0034045--C:pre-autophagosomal structure membrane
GO:0016236--P:macroautophagy
GO:0015031--P:protein transport

KEGG

ani:AN0127.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000966	Aegilops tauschii	32.08	4.00e-46	176.00
IUUC-Aml-001842	Ailuropoda melanoleuca	35.70	6.00e-63	233.00
IUUC-Atr-002710	Amborella trichopoda	31.76	2.00e-42	164.00
IUUC-Apl-003390	Anas platyrhynchos	34.79	1.00e-63	235.00
IUUC-Aca-004975	Anolis carolinensis	35.56	9.00e-67	245.00
IUUC-Aly-006355	Arabidopsis lyrata	29.41	3.00e-41	160.00
IUUC-Ath-007423	Arabidopsis thaliana	30.73	8.00e-41	159.00
IUUC-Ago-007948	Ashbya gossypii	35.83	6.00e-80	290.00
IUUC-Acl-008148	Aspergillus clavatus	85.13	0.00e+00	679.00
IUUC-Afl-008562	Aspergillus flavus	85.75	0.00e+00	668.00
IUUC-Afu-008936	Aspergillus fumigatus	85.32	0.00e+00	711.00
IUUC-Ang-009798	Aspergillus niger	87.95	0.00e+00	679.00
IUUC-Aor-010066	Aspergillus oryzae	85.75	0.00e+00	668.00
IUUC-Ate-010266	Aspergillus terreus	87.20	0.00e+00	696.00
IUUC-Ame-010727	Astyanax mexicanus	36.28	3.00e-68	250.00
IUUC-Bta-012655	Bos taurus	35.39	2.00e-67	247.00
IUUC-Bci-013627	Botrytis cinerea	59.45	7.00e-136	475.00
IUUC-Bdi-014739	Brachypodium distachyon	30.90	1.00e-45	175.00
IUUC-Bol-015492	Brassica oleracea	35.47	8.00e-45	172.00
IUUC-Bra-017319	Brassica rapa	33.70	1.00e-36	145.00
IUUC-Cel-018503	Caenorhabditis elegans	30.41	3.00e-48	183.00
IUUC-Cja-018829	Callithrix jacchus	44.27	5.00e-55	206.00
IUUC-Cfa-020858	Canis familiaris	34.24	3.00e-63	234.00
IUUC-Cpo-022235	Cavia porcellus	44.11	1.00e-59	221.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	34.07	4.00e-42	163.00
IUUC-Csa-023963	Chlorocebus sabaeus	43.48	4.00e-56	210.00
IUUC-Cho-024328	Choloepus hoffmanni	36.34	8.00e-61	226.00
IUUC-Cin-025343	Ciona intestinalis	33.72	4.00e-58	216.00
IUUC-Csv-025920	Ciona savignyi	35.78	4.00e-64	236.00
IUUC-Cgl-026425	Colletotrichum gloeosporioides	70.59	3.00e-56	210.00
IUUC-Cne-026947	Cryptococcus neoformans	52.13	2.00e-104	370.00
IUUC-Dre-027490	Danio rerio	36.04	4.00e-68	249.00
IUUC-Dno-030057	Dasypus novemcinctus	35.45	1.00e-63	235.00
IUUC-Dor-030472	Dipodomys ordii	44.12	2.00e-54	204.00
IUUC-Dse-031215	Dothistroma septosporum	48.73	5.00e-119	419.00
IUUC-Dme-031881	Drosophila melanogaster	34.57	2.00e-31	128.00
IUUC-Ete-032362	Echinops telfairi	32.84	6.00e-55	206.00
IUUC-Eca-034362	Equus caballus	35.45	7.00e-64	236.00
IUUC-Eeu-034479	Erinaceus europaeus	35.48	5.00e-25	105.00
IUUC-Fca-036230	Felis catus	35.54	1.00e-63	235.00
IUUC-Fal-036782	Ficedula albicollis	34.71	2.00e-63	234.00
IUUC-Fox-037797	Fusarium oxysporum	59.23	7.00e-127	445.00
IUUC-Fso-038174	Fusarium solani	57.89	6.00e-126	442.00
IUUC-Gmo-039706	Gadus morhua	34.05	1.00e-60	225.00
IUUC-Ggr-040113	Gaeumannomyces graminis	70.66	1.00e-104	371.00
IUUC-Gga-040690	Gallus gallus	35.15	5.00e-67	246.00
IUUC-Gac-041360	Gasterosteus aculeatus	36.28	1.00e-67	248.00
IUUC-Gma-043876	Glycine max	44.07	4.00e-57	213.00
IUUC-Ggo-045610	Gorilla gorilla	29.33	5.00e-33	133.00
IUUC-Hsa-046782	Homo sapiens	43.87	2.00e-56	211.00
IUUC-Hvu-047851	Hordeum vulgare	30.90	3.00e-46	177.00
IUUC-Itr-048693	Ictidomys tridecemlineatus	43.87	1.00e-56	212.00
IUUC-Kpa-049378	Komagataella pastoris	48.76	4.00e-76	276.00
IUUC-Lch-050413	Latimeria chalumnae	32.73	7.00e-61	226.00
IUUC-Lpe-051205	Leersia perrieri	32.22	1.00e-47	182.00
IUUC-Loc-052379	Lepisosteus oculatus	34.80	4.00e-40	156.00
IUUC-Lma-052948	Leptosphaeria maculans	62.09	9.00e-155	538.00
IUUC-Laf-054007	Loxodonta africana	35.80	5.00e-67	246.00
IUUC-Mcc-055304	Macaca mulatta	34.96	6.00e-39	152.00
IUUC-Meu-056020	Macropus eugenii	31.10	2.00e-32	131.00
IUUC-Mor-057125	Magnaporthe oryzae	56.89	2.00e-137	480.00
IUUC-Mpo-057416	Magnaporthe poae	29.26	1.00e-30	125.00
IUUC-Mtr-058536	Medicago truncatula	31.89	2.00e-45	174.00
IUUC-Mla-058885	Melampsora laricipopulina	22.64	2.00e-13	67.40
IUUC-Mga-059795	Meleagris gallopavo	34.79	1.00e-63	234.00
IUUC-Mvi-060219	Microbotryum violaceum	47.91	1.00e-103	367.00
IUUC-Mmr-061096	Microcebus murinus	33.71	1.00e-63	234.00
IUUC-Mdo-062881	Monodelphis domestica	35.39	9.00e-67	245.00
IUUC-Mmu-063787	Mus musculus	44.15	2.00e-60	224.00
IUUC-Mac-064838	Musa acuminata	37.74	2.00e-47	181.00
IUUC-Mpu-066019	Mustela putorius furo	42.86	1.00e-57	215.00
IUUC-Mlu-068016	Myotis lucifugus	36.19	5.00e-67	246.00
IUUC-Nfi-068424	Neosartorya fischeri	86.95	0.00e+00	721.00
IUUC-Ncr-068833	Neurospora crassa	55.53	8.00e-132	461.00
IUUC-Nle-069047	Nomascus leucogenys	34.63	7.00e-43	165.00
IUUC-Opr-070933	Ochotona princeps	47.06	4.00e-39	153.00
IUUC-Ont-072495	Oreochromis niloticus	36.52	6.00e-68	249.00
IUUC-Oan-073084	Ornithorhynchus anatinus	35.43	8.00e-61	225.00
IUUC-Ocu-074689	Oryctolagus cuniculus	44.49	7.00e-60	222.00
IUUC-Oba-075601	Oryza barthii	40.38	1.00e-40	158.00
IUUC-Obr-076476	Oryza brachyantha	31.74	2.00e-47	181.00
IUUC-Ogl-077630	Oryza glaberrima	32.22	1.00e-47	182.00
IUUC-Ogu-078089	Oryza glumaepatula	40.38	9.00e-41	159.00
IUUC-Oin-079071	Oryza indica	40.38	9.00e-41	159.00
IUUC-Olo-080657	Oryza longistaminata	32.70	2.00e-45	176.00
IUUC-Ome-081702	Oryza meridionalis	31.74	2.00e-44	171.00
IUUC-Oni-083063	Oryza nivara	40.38	9.00e-41	159.00
IUUC-Opu-083460	Oryza punctata	32.46	3.00e-46	178.00
IUUC-Oru-084845	Oryza rufipogon	40.38	9.00e-41	159.00
IUUC-Osa-086113	Oryza sativa	40.38	9.00e-41	159.00
IUUC-Ola-086628	Oryzias latipes	35.69	4.00e-44	169.00
IUUC-Olu-087808	Ostreococcus lucimarinus	32.47	2.00e-42	164.00
IUUC-Oga-088894	Otolemur garnettii	43.87	1.00e-56	211.00
IUUC-Oar-089850	Ovis aries	34.79	5.00e-64	236.00
IUUC-Ptr-090456	Pan troglodytes	43.87	1.00e-56	211.00
IUUC-Pan-092111	Papio anubis	44.11	7.00e-60	223.00
IUUC-Psi-094095	Pelodiscus sinensis	35.04	4.00e-64	236.00
IUUC-Pma-094403	Petromyzon marinus	29.86	2.00e-31	127.00
IUUC-Pno-095015	Phaeosphaeria nodorum	62.17	2.00e-146	510.00
IUUC-Ppa-095480	Physcomitrella patens	31.22	2.00e-43	168.00
IUUC-Pfo-096987	Poecilia formosa	35.63	1.00e-67	248.00
IUUC-Pab-097754	Pongo abelii	43.87	3.00e-56	210.00
IUUC-Pop-099157	Populus trichocarpa	29.48	6.00e-41	159.00
IUUC-Pca-100176	Procavia capensis	27.42	4.00e-26	110.00
IUUC-Ppe-101799	Prunus persica	31.07	9.00e-40	155.00
IUUC-Pva-103047	Pteropus vampyrus	34.48	1.00e-63	234.00
IUUC-Pgr-103258	Puccinia graminis	23.53	2.00e-12	65.90
IUUC-Ptt-103915	Puccinia triticina	24.54	7.00e-19	87.00
IUUC-Pte-104139	Pyrenophora teres	62.32	1.00e-144	504.00
IUUC-Pyt-104488	Pyrenophora triticirepentis	60.33	2.00e-143	500.00
IUUC-Rno-105990	Rattus norvegicus	44.53	7.00e-61	226.00
IUUC-Sce-106327	Saccharomyces cerevisiae	37.70	3.00e-83	300.00
IUUC-Sha-106581	Sarcophilus harrisii	35.45	6.00e-64	236.00
IUUC-Sja-107913	Schizosaccharomyces japonicus	39.71	7.00e-79	285.00
IUUC-Spo-108068	Schizosaccharomyces pombe	41.73	7.00e-77	278.00
IUUC-Ssl-108418	Sclerotinia sclerotiorum	59.06	2.00e-144	503.00
IUUC-Smo-108755	Selaginella moellendorffii	32.31	3.00e-53	201.00
IUUC-Sit-110095	Setaria italica	31.50	1.00e-44	172.00
IUUC-Sly-111030	Solanum lycopersicum	29.91	8.00e-45	172.00
IUUC-Stu-112534	Solanum tuberosum	34.04	6.00e-38	149.00
IUUC-Sar-113276	Sorex araneus	36.02	7.00e-26	108.00
IUUC-Sbi-114020	Sorghum bicolor	30.99	2.00e-45	174.00
IUUC-Sre-115219	Sporisorium reilianum	50.34	3.00e-105	373.00
IUUC-Ssc-116360	Sus scrofa	35.39	5.00e-67	246.00
IUUC-Tgu-116951	Taeniopygia guttata	34.79	7.00e-64	236.00
IUUC-Tru-117889	Takifugu rubripes	35.09	4.00e-65	240.00
IUUC-Tsy-119533	Tarsius syrichta	44.30	9.00e-18	81.60
IUUC-Tni-119729	Tetraodon nigroviridis	35.00	2.00e-35	141.00
IUUC-Tca-121732	Theobroma cacao	30.12	7.00e-38	149.00
IUUC-Tre-121895	Trichoderma reesei	59.36	2.00e-140	490.00
IUUC-Tvi-122311	Trichoderma virens	59.73	2.00e-142	496.00
IUUC-Tae-124901	Triticum aestivum	32.71	2.00e-46	178.00
IUUC-Tur-126757	Triticum urartu	31.38	6.00e-45	172.00
IUUC-Ttr-128940	Tursiops truncatus	34.82	4.00e-35	139.00
IUUC-Uma-129438	Ustilago maydis	49.65	1.00e-96	345.00
IUUC-Vda-129782	Verticillium dahliae	55.10	1.00e-95	341.00
IUUC-Vvi-131674	Vitis vinifera	30.42	7.00e-48	182.00
IUUC-Xtr-131806	Xenopus tropicalis	34.98	5.00e-43	166.00
IUUC-Xma-133370	Xiphophorus maculatus	35.63	1.00e-67	248.00
IUUC-Yli-134337	Yarrowia lipolytica	49.09	2.00e-101	360.00
IUUC-Zma-135654	Zea mays	30.77	2.00e-44	171.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence