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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063230
Ensembl Protein ID ENSMUSP00000110342.2
UniProt Accession Q8K0L9; A6X916; Q9DBD4; Q9QZ87; ZBT20_MOUSE
Genbank Protein ID AAF06015.1; BAB23755.1; CAO77851.1; CAO77852.1; AAH31114.1; AAH56446.1
Protein Name Zinc finger and BTB domain-containing protein 20; BTB/POZ domain zinc finger factor HOF; Zinc finger protein 288
Genbank Nucleotide ID AF194030; AK005028; CT010512; CT010512; BC031114; BC056446
Gene Name Zbtb20; Zfp288
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022708.16 ENSMUST00000151244.7 ENSMUSP00000124984.1
ENSMUSG00000022708.16 ENSMUST00000114694.8 ENSMUSP00000110342.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 2.60e-07 32.0 104 165
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv++ + g+  +ah++vLaa S++F++ +l + ++       ei   v+ ++++ l++F+Y+g l+ 
   Q: 104  CDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDI------EIPSvVSVQSVQKLIDFMYSGVLRV 165
           8*****************************9888875......577557788************9976 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (By similarity). Binds to DNA.
 May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (By similarity). Binds to DNA.
Protein Sequence
(Fasta)
MLERKKPKTA ENQKASEENE ITQPGGSSAK PALPCLNFEA VLSPAPALIH STHSLTNSHA 60
HTGSSDCDIS CKGMTERIHS INLHNFSNSV LETLNEQRNR GHFCDVTVRI HGSMLRAHRC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063230|E3,BTB_Other|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAAGTTTAG GAGTTGAGGA AAGAAGATTA AAGAGCGCGA GGAGGTAACG CCAAAAACTC 60
TAATTTGTTG TGGGGCGGGC GGGAGGGAGG GGTGTGTGCG TGCGGAGCGC GGCCGGGCGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063230|E3,BTB_Other|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0010629--P:negative regulation of gene expression
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:0006351--P:transcription, DNA-templated
KEGG mmu:56490
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002366 Ailuropoda melanoleuca 97.44 0.00e+00 1380.00
IUUC-Apl-003862 Anas platyrhynchos 88.89 0.00e+00 1300.00
IUUC-Aca-005090 Anolis carolinensis 85.91 0.00e+00 1261.00
IUUC-Ame-010940 Astyanax mexicanus 67.19 0.00e+00 721.00
IUUC-Bta-012346 Bos taurus 97.15 0.00e+00 1415.00
IUUC-Bci-013652 Botrytis cinerea 28.91 1.30e+00 29.30
IUUC-Cja-019161 Callithrix jacchus 97.84 0.00e+00 1414.00
IUUC-Cfa-020769 Canis familiaris 97.71 0.00e+00 1383.00
IUUC-Cpo-021745 Cavia porcellus 95.96 0.00e+00 1354.00
IUUC-Csa-024179 Chlorocebus sabaeus 98.35 0.00e+00 1273.00
IUUC-Cho-024960 Choloepus hoffmanni 95.88 0.00e+00 910.00
IUUC-Dre-028517 Danio rerio 67.30 0.00e+00 712.00
IUUC-Dno-029085 Dasypus novemcinctus 97.17 0.00e+00 1389.00
IUUC-Dor-030803 Dipodomys ordii 97.98 0.00e+00 1412.00
IUUC-Ete-032886 Echinops telfairi 97.74 2.00e-153 536.00
IUUC-Eca-034022 Equus caballus 97.46 0.00e+00 1237.00
IUUC-Eeu-035184 Erinaceus europaeus 96.41 0.00e+00 1236.00
IUUC-Fca-035822 Felis catus 95.68 0.00e+00 1363.00
IUUC-Fal-036868 Ficedula albicollis 89.85 0.00e+00 1188.00
IUUC-Gmo-038534 Gadus morhua 87.01 2.00e-75 275.00
IUUC-Gga-040560 Gallus gallus 88.39 0.00e+00 1292.00
IUUC-Gac-042540 Gasterosteus aculeatus 63.03 0.00e+00 745.00
IUUC-Ggo-045443 Gorilla gorilla 97.57 0.00e+00 1415.00
IUUC-Hsa-046472 Homo sapiens 97.71 0.00e+00 1417.00
IUUC-Itr-048471 Ictidomys tridecemlineatus 96.90 0.00e+00 1398.00
IUUC-Lch-050620 Latimeria chalumnae 77.78 0.00e+00 975.00
IUUC-Loc-051793 Lepisosteus oculatus 74.06 0.00e+00 870.00
IUUC-Laf-053382 Loxodonta africana 96.37 0.00e+00 1399.00
IUUC-Mcc-055395 Macaca mulatta 98.24 0.00e+00 1412.00
IUUC-Meu-056456 Macropus eugenii 92.98 0.00e+00 1274.00
IUUC-Mga-059977 Meleagris gallopavo 88.04 0.00e+00 1301.00
IUUC-Mmr-061361 Microcebus murinus 98.11 0.00e+00 1425.00
IUUC-Mdo-062760 Monodelphis domestica 91.39 0.00e+00 1200.00
IUUC-Mpu-066367 Mustela putorius furo 97.44 0.00e+00 1387.00
IUUC-Mlu-067638 Myotis lucifugus 96.90 0.00e+00 1381.00
IUUC-Nle-069275 Nomascus leucogenys 97.50 0.00e+00 1163.00
IUUC-Opr-070230 Ochotona princeps 93.50 0.00e+00 862.00
IUUC-Ont-071373 Oreochromis niloticus 63.04 0.00e+00 754.00
IUUC-Ocu-073942 Oryctolagus cuniculus 96.64 0.00e+00 1402.00
IUUC-Oga-088490 Otolemur garnettii 97.96 0.00e+00 1418.00
IUUC-Oar-090130 Ovis aries 77.17 0.00e+00 1041.00
IUUC-Ptr-090567 Pan troglodytes 97.75 0.00e+00 1271.00
IUUC-Pan-092221 Papio anubis 98.25 0.00e+00 1417.00
IUUC-Psi-093694 Pelodiscus sinensis 89.35 6.00e-86 310.00
IUUC-Pfo-096692 Poecilia formosa 61.59 0.00e+00 753.00
IUUC-Pab-098500 Pongo abelii 97.57 0.00e+00 1410.00
IUUC-Pca-100185 Procavia capensis 97.30 0.00e+00 730.00
IUUC-Pva-102151 Pteropus vampyrus 97.26 0.00e+00 843.00
IUUC-Rno-105171 Rattus norvegicus 98.65 0.00e+00 1280.00
IUUC-Sha-106646 Sarcophilus harrisii 90.80 0.00e+00 1322.00
IUUC-Sar-113486 Sorex araneus 96.41 0.00e+00 1207.00
IUUC-Ssc-116214 Sus scrofa 98.07 0.00e+00 1257.00
IUUC-Tgu-117045 Taeniopygia guttata 89.46 0.00e+00 1334.00
IUUC-Tru-118699 Takifugu rubripes 60.64 0.00e+00 736.00
IUUC-Tsy-119393 Tarsius syrichta 95.14 0.00e+00 1363.00
IUUC-Tni-119917 Tetraodon nigroviridis 61.28 0.00e+00 723.00
IUUC-Vpa-130539 Vicugna pacos 96.84 0.00e+00 1128.00
IUUC-Xtr-132883 Xenopus tropicalis 80.73 0.00e+00 1157.00
Created Date 25-Jun-2017

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