iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000017919.6	ENSPTRT00000033086.5	ENSPTRP00000030567.5
ENSPTRG00000017919.6	ENSPTRT00000062065.2	ENSPTRP00000054616.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.60e-08	33.5	16	61
E3 activity/RING/U-box	6.20e-07	29.4	11	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw...pglknssskefrCPlCr 46
           C+iC+  +++ p++ +CgH f++ Cl ++   pg+      + +CPlC+
   Q: 16   CPICQGTLRE-PVTIDCGHNFCRACLTRYceiPGPD--LEESPTCPLCK 61
           ********99.*******************987777..889999****7 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk......tcPvtrqplteedlvPnltlrrli 65
            +e +CpI     r+Pv++ +G+ + r+++ ++ +  g       tcP++++p+++ ++ Pn  l +++
   Q: 11   ADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPdleespTCPLCKEPFRPGSFRPNWQLANVV 79
           57899*****************************444444555579****************9987776 PP

Organism

Pan troglodytes

Functional Description
(View)

Seems to play an important role in erythropoiesis.

Protein Sequence
(Fasta)

MASAASVTSL ADEVNCPICQ GTLREPVTID CGHNFCRACL TRYCEIPGPD LEESPTCPLC 60
KEPFRPGSFR PNWQLANVVE NIERLQLVST LGLGEEDVCQ EHGEKIYFFC EDDEMQLCVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTGTGTGA CCCAGCCCTT CCCCCGTGGC CAAGCAGAGA GAGTGGCCTA GAGGAAGCCA 60
TAGCAGCAGT ACCAGCATGG CCTCTGCCGC CTCTGTGACC AGCCTGGCAG ATGAAGTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0008270--F:zinc ion binding
GO:0030218--P:erythrocyte differentiation
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

ptr:742346

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002355	Ailuropoda melanoleuca	83.58	0.00e+00	802.00
IUUC-Bta-012587	Bos taurus	85.24	0.00e+00	820.00
IUUC-Cja-018721	Callithrix jacchus	95.01	0.00e+00	917.00
IUUC-Cfa-020759	Canis familiaris	81.72	0.00e+00	771.00
IUUC-Cpo-022485	Cavia porcellus	71.93	0.00e+00	679.00
IUUC-Csa-023679	Chlorocebus sabaeus	96.26	0.00e+00	926.00
IUUC-Cho-024918	Choloepus hoffmanni	69.17	3.00e-94	337.00
IUUC-Dno-028912	Dasypus novemcinctus	74.90	0.00e+00	743.00
IUUC-Dor-030459	Dipodomys ordii	77.64	0.00e+00	769.00
IUUC-Ete-032226	Echinops telfairi	82.84	1.00e-165	575.00
IUUC-Eca-034379	Equus caballus	86.07	0.00e+00	857.00
IUUC-Eeu-035312	Erinaceus europaeus	80.04	0.00e+00	795.00
IUUC-Fca-036106	Felis catus	79.00	0.00e+00	757.00
IUUC-Ggo-045433	Gorilla gorilla	98.54	0.00e+00	977.00
IUUC-Hsa-046260	Homo sapiens	98.34	0.00e+00	947.00
IUUC-Itr-048465	Ictidomys tridecemlineatus	82.89	0.00e+00	771.00
IUUC-Laf-054405	Loxodonta africana	87.08	0.00e+00	866.00
IUUC-Mcc-055599	Macaca mulatta	96.67	0.00e+00	932.00
IUUC-Meu-056471	Macropus eugenii	63.31	7.00e-123	433.00
IUUC-Mmr-061779	Microcebus murinus	78.75	0.00e+00	746.00
IUUC-Mdo-062384	Monodelphis domestica	74.59	0.00e+00	716.00
IUUC-Mmu-063430	Mus musculus	83.75	0.00e+00	803.00
IUUC-Mpu-066787	Mustela putorius furo	80.86	0.00e+00	771.00
IUUC-Mlu-067590	Myotis lucifugus	73.14	3.00e-122	431.00
IUUC-Nle-069295	Nomascus leucogenys	97.92	0.00e+00	943.00
IUUC-Oan-072904	Ornithorhynchus anatinus	41.35	2.00e-82	299.00
IUUC-Ocu-074896	Oryctolagus cuniculus	85.44	0.00e+00	657.00
IUUC-Oga-088589	Otolemur garnettii	88.54	0.00e+00	850.00
IUUC-Oar-089521	Ovis aries	84.53	0.00e+00	798.00
IUUC-Pan-092682	Papio anubis	96.47	0.00e+00	899.00
IUUC-Pab-098559	Pongo abelii	97.28	0.00e+00	712.00
IUUC-Pca-100591	Procavia capensis	74.90	0.00e+00	720.00
IUUC-Pva-103067	Pteropus vampyrus	85.24	0.00e+00	796.00
IUUC-Rno-105824	Rattus norvegicus	82.71	0.00e+00	823.00
IUUC-Sha-107385	Sarcophilus harrisii	75.83	0.00e+00	751.00
IUUC-Sar-113541	Sorex araneus	86.93	9.00e-158	548.00
IUUC-Ssc-115893	Sus scrofa	84.65	0.00e+00	838.00
IUUC-Tsy-119290	Tarsius syrichta	89.05	3.00e-169	587.00
IUUC-Tbe-127565	Tupaia belangeri	82.10	3.00e-109	388.00
IUUC-Ttr-128456	Tursiops truncatus	83.99	0.00e+00	802.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence