iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132333

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

SH3 domain-containing ring finger 2

Genbank Nucleotide ID

AAMC01043838

Gene Name

sh3rf2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000002319.3	ENSXETT00000004953.3	ENSXETP00000004953.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.70e-08	33.3	12	53
UBD/SH3	2.10e-23	82.2	385	440

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl  ++   +vlpC+H+f++ Clq++     +++ke +CP Cr
   Q: 12   CPLCLGKLDVNAKVLPCQHTFCQPCLQRL----FKAKKELKCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + + vl++y+a+  +e+ l++G+ v+++   +  egWl+gv+  +gk GlfP+  v  
   Q: 385  NMCVVLHPYMANGPEEMDLQRGEGVRIL--GKFQEGWLRGVSLVTGKIGLFPSHCVSP 440
           6899************************..88889*****************987765 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MDELVVLDLL DCPLCLGKLD VNAKVLPCQH TFCQPCLQRL FKAKKELKCP ECRTPVQCSI 60
EELPANLLLV RILDGLRGGQ TLLRRNSSRR MGGLFAQDSL KKSKANRASQ DSTSRTISKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGAAT TGGTTGTTCT TGACCTCCTG GATTGCCCCT TATGCCTTGG AAAATTGGAT 60
GTTAATGCCA AGGTGCTGCC ATGCCAACAT ACCTTTTGCC AGCCTTGTCT GCAGAGGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028511--SH3RF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF00097--zf-C3HC4

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	49.40	8.00e-127	447.00
IUUC-Apl-003443	Anas platyrhynchos	50.55	3.00e-115	409.00
IUUC-Aca-004632	Anolis carolinensis	46.32	9.00e-120	424.00
IUUC-Bta-013400	Bos taurus	49.77	8.00e-132	464.00
IUUC-Cja-019686	Callithrix jacchus	44.49	6.00e-118	417.00
IUUC-Cfa-020893	Canis familiaris	49.55	6.00e-128	451.00
IUUC-Cpo-021638	Cavia porcellus	47.72	3.00e-133	468.00
IUUC-Csa-023846	Chlorocebus sabaeus	48.20	1.00e-133	470.00
IUUC-Dno-028940	Dasypus novemcinctus	49.03	2.00e-134	472.00
IUUC-Ete-032513	Echinops telfairi	49.70	4.00e-140	491.00
IUUC-Eca-034241	Equus caballus	49.25	1.00e-138	486.00
IUUC-Eeu-034636	Erinaceus europaeus	52.37	5.00e-108	385.00
IUUC-Fca-035862	Felis catus	49.62	7.00e-133	467.00
IUUC-Gga-040748	Gallus gallus	40.00	4.00e-101	362.00
IUUC-Ggo-045267	Gorilla gorilla	47.58	3.00e-128	452.00
IUUC-Hsa-045761	Homo sapiens	47.43	1.00e-126	447.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	48.64	4.00e-132	465.00
IUUC-Laf-054061	Loxodonta africana	41.77	6.00e-82	298.00
IUUC-Mcc-054746	Macaca mulatta	47.99	2.00e-125	442.00
IUUC-Meu-056390	Macropus eugenii	62.99	8.00e-37	148.00
IUUC-Mmr-061390	Microcebus murinus	44.94	1.00e-103	370.00
IUUC-Mdo-062951	Monodelphis domestica	50.37	6.00e-151	527.00
IUUC-Mmu-063840	Mus musculus	46.50	3.00e-127	449.00
IUUC-Mpu-065840	Mustela putorius furo	50.30	4.00e-137	481.00
IUUC-Mlu-067378	Myotis lucifugus	49.03	1.00e-122	433.00
IUUC-Ncr-068956	Neurospora crassa	31.94	4.00e-07	50.10
IUUC-Nle-069535	Nomascus leucogenys	47.30	4.00e-119	422.00
IUUC-Opr-070739	Ochotona princeps	47.81	3.00e-134	472.00
IUUC-Oan-073468	Ornithorhynchus anatinus	49.10	1.00e-132	466.00
IUUC-Ocu-074343	Oryctolagus cuniculus	49.55	2.00e-128	453.00
IUUC-Oga-088276	Otolemur garnettii	44.65	3.00e-116	412.00
IUUC-Oar-090315	Ovis aries	49.63	4.00e-129	455.00
IUUC-Ptr-091119	Pan troglodytes	48.56	1.00e-127	450.00
IUUC-Pan-092158	Papio anubis	51.77	3.00e-117	415.00
IUUC-Psi-092959	Pelodiscus sinensis	45.56	3.00e-130	459.00
IUUC-Pab-097675	Pongo abelii	47.75	1.00e-123	436.00
IUUC-Pca-101021	Procavia capensis	45.93	3.00e-116	412.00
IUUC-Pva-102619	Pteropus vampyrus	49.32	4.00e-132	465.00
IUUC-Rno-105918	Rattus norvegicus	47.24	6.00e-129	454.00
IUUC-Sha-107391	Sarcophilus harrisii	49.03	2.00e-153	535.00
IUUC-Sar-113148	Sorex araneus	53.78	9.00e-104	370.00
IUUC-Tbe-128007	Tupaia belangeri	51.81	4.00e-118	418.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence