iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040764

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Histone-binding protein RBBP7; Retinoblastoma-binding protein 7; Retinoblastoma-binding protein p46

Genbank Nucleotide ID

AF279275

Gene Name

RBBP7; RBAP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000016546.4	ENSGALT00000026698.4	ENSGALP00000026647.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.40e-37	124.3	312	346

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           Ht++v+cl+f   s+ +l++Gs D+t+ +WDlr  
   Q: 312  HTAEVNCLSFnpySEFILATGSADKTVALWDLRNL 346
           **********96554568*************9875 PP

Organism

Gallus gallus

Functional Description
(View)

Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.

Protein Sequence
(Fasta)

MRRGASWNLA SWRAAGGAVP PLGAVTCCAR LLPSLPVVCA SEMASKEVLE DTVEERVISE 60
EYKIWKKNTP FLYDLVMTHA LEWPSLTVQW LPDVSRPEGK DYALHWLVLG THTSDEQNHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTGGCGGT GGCGCATGCG CCGCGGCGCG AGTTGGAACT TGGCGAGCTG GCGCGCGGCG 60
GGAGGAGCTG TACCGCCTCT GGGCGCCGTT ACCTGCTGTG CTCGTTTGTT GCCGTCTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0143--Chaperone
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0235--DNA replication
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR022052--Histone-bd_RBBP4_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12265--CAF1C_H4-bd
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0035098--C:ESC/E(Z) complex
GO:0005634--C:nucleus
GO:0016581--C:NuRD complex
GO:0003723--F:RNA binding
GO:0070370--P:cellular heat acclimation
GO:0016569--P:covalent chromatin modification
GO:0006260--P:DNA replication
GO:0030308--P:negative regulation of cell growth
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

gga:395390

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001256	Ailuropoda melanoleuca	93.60	0.00e+00	822.00
IUUC-Apl-003357	Anas platyrhynchos	95.56	0.00e+00	838.00
IUUC-Bta-013455	Bos taurus	93.88	0.00e+00	829.00
IUUC-Cja-019957	Callithrix jacchus	93.36	0.00e+00	820.00
IUUC-Cfa-020917	Canis familiaris	93.60	0.00e+00	823.00
IUUC-Cpo-022173	Cavia porcellus	93.65	0.00e+00	829.00
IUUC-Csa-023738	Chlorocebus sabaeus	93.65	0.00e+00	829.00
IUUC-Dno-029206	Dasypus novemcinctus	93.88	0.00e+00	831.00
IUUC-Dor-030733	Dipodomys ordii	80.57	0.00e+00	691.00
IUUC-Eca-034138	Equus caballus	93.60	0.00e+00	821.00
IUUC-Fca-035977	Felis catus	90.07	0.00e+00	823.00
IUUC-Fal-037538	Ficedula albicollis	92.64	0.00e+00	813.00
IUUC-Hsa-045677	Homo sapiens	93.65	0.00e+00	829.00
IUUC-Itr-048060	Ictidomys tridecemlineatus	93.79	0.00e+00	819.00
IUUC-Lch-050545	Latimeria chalumnae	92.52	0.00e+00	825.00
IUUC-Lma-053275	Leptosphaeria maculans	45.92	1.00e-69	256.00
IUUC-Laf-053973	Loxodonta africana	93.90	0.00e+00	827.00
IUUC-Mcc-055687	Macaca mulatta	93.65	0.00e+00	829.00
IUUC-Mga-059209	Meleagris gallopavo	94.81	0.00e+00	829.00
IUUC-Mmr-061008	Microcebus murinus	93.36	0.00e+00	821.00
IUUC-Mdo-062817	Monodelphis domestica	96.71	0.00e+00	851.00
IUUC-Mmu-063773	Mus musculus	93.88	0.00e+00	831.00
IUUC-Mpu-066722	Mustela putorius furo	93.60	0.00e+00	822.00
IUUC-Mlu-067813	Myotis lucifugus	93.60	0.00e+00	822.00
IUUC-Nle-070023	Nomascus leucogenys	90.07	0.00e+00	822.00
IUUC-Oan-073579	Ornithorhynchus anatinus	96.24	0.00e+00	847.00
IUUC-Ocu-074778	Oryctolagus cuniculus	93.41	0.00e+00	828.00
IUUC-Oga-088987	Otolemur garnettii	86.52	0.00e+00	738.00
IUUC-Oar-090250	Ovis aries	93.84	0.00e+00	818.00
IUUC-Ptr-091598	Pan troglodytes	93.81	0.00e+00	821.00
IUUC-Pan-092412	Papio anubis	93.65	0.00e+00	829.00
IUUC-Psi-093162	Pelodiscus sinensis	97.18	0.00e+00	783.00
IUUC-Pab-097865	Pongo abelii	93.65	0.00e+00	829.00
IUUC-Pva-102369	Pteropus vampyrus	93.60	0.00e+00	823.00
IUUC-Pyt-104516	Pyrenophora triticirepentis	49.13	7.00e-112	397.00
IUUC-Rno-105892	Rattus norvegicus	93.65	0.00e+00	829.00
IUUC-Sha-107575	Sarcophilus harrisii	96.24	0.00e+00	845.00
IUUC-Sar-113236	Sorex araneus	85.78	0.00e+00	721.00
IUUC-Ssc-116352	Sus scrofa	93.60	0.00e+00	823.00
IUUC-Tsy-118854	Tarsius syrichta	93.36	0.00e+00	821.00
IUUC-Tur-126850	Triticum urartu	64.01	3.00e-117	414.00
IUUC-Tbe-128010	Tupaia belangeri	78.00	0.00e+00	714.00
IUUC-Ttr-128558	Tursiops truncatus	83.10	0.00e+00	709.00
IUUC-Vpa-130664	Vicugna pacos	94.29	0.00e+00	823.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence