iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-063056

Ensembl Protein ID

ENSMODP00000003470.3

UniProt Accession

F7E2M8; F7E2M8_MONDO

Protein Name

Uncharacterized protein

Gene Name

DCAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000002855.3	ENSMODT00000003547.3	ENSMODP00000003470.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-17	63.1	92	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgti 25
           gH + +++ +f    +d+ +vs+s+Dg+i
   Q: 92   GHRANIFSAKFlpctNDKQIVSCSGDGVI 120
           8************9777**********98 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSRGGCCPHL LWDVRKRSLG LEDPSRLRSR YLGRREFIQR LKLEATLNVH DGCVNTICWN 60
DTGEYILSGS DDTNLVISNP YSRKVLTTIR SGHRANIFSA KFLPCTNDKQ IVSCSGDGVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTCCATCC TGTATCCACA CCTACTCATA CCCAGCCTCC TCCTCCTCCT CTTGGAAGCG 60
GGCTAAGGGA GGAGACATCA GCGGTGCTCT GGAAGAGAGA ATGAGACGAG CTCCGGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000048--IQ_motif_EF-hand-BS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50096--IQ
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0005634--C:nucleus
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001399	Ailuropoda melanoleuca	90.00	0.00e+00	813.00
IUUC-Apl-003181	Anas platyrhynchos	78.78	0.00e+00	1178.00
IUUC-Aca-004953	Anolis carolinensis	66.67	0.00e+00	784.00
IUUC-Acl-008211	Aspergillus clavatus	27.04	1.00e-26	115.00
IUUC-Afu-008828	Aspergillus fumigatus	27.73	9.00e-28	119.00
IUUC-Ate-010555	Aspergillus terreus	26.40	2.00e-25	111.00
IUUC-Ame-011314	Astyanax mexicanus	85.71	0.00e+00	664.00
IUUC-Bta-013552	Bos taurus	84.92	0.00e+00	1345.00
IUUC-Cja-019015	Callithrix jacchus	93.48	0.00e+00	825.00
IUUC-Cfa-021249	Canis familiaris	93.04	0.00e+00	809.00
IUUC-Cpo-021903	Cavia porcellus	91.52	0.00e+00	822.00
IUUC-Csa-023744	Chlorocebus sabaeus	93.04	0.00e+00	825.00
IUUC-Cho-024527	Choloepus hoffmanni	76.80	3.00e-167	582.00
IUUC-Dre-028040	Danio rerio	85.99	0.00e+00	666.00
IUUC-Dno-029777	Dasypus novemcinctus	93.48	0.00e+00	824.00
IUUC-Dor-030879	Dipodomys ordii	82.39	0.00e+00	753.00
IUUC-Ete-032607	Echinops telfairi	73.14	1.00e-133	471.00
IUUC-Eca-033396	Equus caballus	82.94	0.00e+00	1220.00
IUUC-Eeu-034944	Erinaceus europaeus	62.61	2.00e-122	433.00
IUUC-Fca-036020	Felis catus	81.82	0.00e+00	1288.00
IUUC-Fal-037527	Ficedula albicollis	76.46	0.00e+00	786.00
IUUC-Gmo-039347	Gadus morhua	83.19	0.00e+00	633.00
IUUC-Gga-040564	Gallus gallus	76.64	0.00e+00	1179.00
IUUC-Gac-042029	Gasterosteus aculeatus	84.46	0.00e+00	645.00
IUUC-Ggo-045634	Gorilla gorilla	81.90	9.00e-171	593.00
IUUC-Hsa-045743	Homo sapiens	83.33	0.00e+00	1288.00
IUUC-Itr-048064	Ictidomys tridecemlineatus	81.99	0.00e+00	1225.00
IUUC-Lch-050457	Latimeria chalumnae	83.66	0.00e+00	702.00
IUUC-Loc-052880	Lepisosteus oculatus	87.04	0.00e+00	667.00
IUUC-Lma-053032	Leptosphaeria maculans	29.61	2.00e-27	117.00
IUUC-Laf-053836	Loxodonta africana	79.37	0.00e+00	933.00
IUUC-Mcc-055749	Macaca mulatta	93.04	0.00e+00	823.00
IUUC-Mga-059293	Meleagris gallopavo	75.64	0.00e+00	1090.00
IUUC-Mmr-060923	Microcebus murinus	93.26	0.00e+00	822.00
IUUC-Mmu-063121	Mus musculus	78.34	0.00e+00	1271.00
IUUC-Mpu-066035	Mustela putorius furo	89.15	0.00e+00	739.00
IUUC-Mlu-067903	Myotis lucifugus	80.55	0.00e+00	1251.00
IUUC-Nfi-068606	Neosartorya fischeri	27.48	3.00e-27	117.00
IUUC-Nle-069415	Nomascus leucogenys	92.99	0.00e+00	774.00
IUUC-Opr-070809	Ochotona princeps	68.98	6.00e-105	375.00
IUUC-Ont-071470	Oreochromis niloticus	84.03	0.00e+00	646.00
IUUC-Oan-072748	Ornithorhynchus anatinus	96.28	4.00e-132	464.00
IUUC-Ocu-073865	Oryctolagus cuniculus	80.99	0.00e+00	1221.00
IUUC-Ola-086755	Oryzias latipes	82.91	0.00e+00	642.00
IUUC-Oga-088309	Otolemur garnettii	89.53	0.00e+00	678.00
IUUC-Oar-090264	Ovis aries	92.83	0.00e+00	830.00
IUUC-Ptr-090603	Pan troglodytes	93.48	0.00e+00	828.00
IUUC-Pan-092480	Papio anubis	81.70	0.00e+00	1292.00
IUUC-Psi-092973	Pelodiscus sinensis	77.82	0.00e+00	909.00
IUUC-Pfo-096506	Poecilia formosa	83.19	0.00e+00	640.00
IUUC-Pab-097581	Pongo abelii	79.93	0.00e+00	1213.00
IUUC-Pca-100155	Procavia capensis	87.15	0.00e+00	734.00
IUUC-Pva-103022	Pteropus vampyrus	94.40	0.00e+00	686.00
IUUC-Pte-104187	Pyrenophora teres	28.97	3.00e-27	117.00
IUUC-Pyt-104546	Pyrenophora triticirepentis	29.21	2.00e-26	114.00
IUUC-Rno-105851	Rattus norvegicus	90.00	0.00e+00	819.00
IUUC-Sha-106790	Sarcophilus harrisii	82.17	0.00e+00	1318.00
IUUC-Sja-107779	Schizosaccharomyces japonicus	32.59	4.00e-34	139.00
IUUC-Spo-108129	Schizosaccharomyces pombe	32.54	2.00e-33	137.00
IUUC-Ssc-115674	Sus scrofa	97.42	2.00e-90	323.00
IUUC-Tgu-116760	Taeniopygia guttata	78.93	0.00e+00	1132.00
IUUC-Tru-118422	Takifugu rubripes	84.18	0.00e+00	639.00
IUUC-Tni-120340	Tetraodon nigroviridis	83.90	0.00e+00	637.00
IUUC-Tbe-127997	Tupaia belangeri	63.93	0.00e+00	899.00
IUUC-Ttr-129311	Tursiops truncatus	75.58	0.00e+00	1194.00
IUUC-Vpa-130145	Vicugna pacos	91.80	0.00e+00	746.00
IUUC-Xtr-132496	Xenopus tropicalis	79.80	0.00e+00	664.00
IUUC-Xma-133610	Xiphophorus maculatus	84.03	0.00e+00	643.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence