iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022025

Ensembl Protein ID

ENSCPOP00000002169.2

UniProt Accession

H0UYF9; H0UYF9_CAVPO

Genbank Protein ID

ENSCPOP00000002169

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02007386

Gene Name

WDR90

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000002385.3	ENSCPOT00000002418.2	ENSCPOP00000002169.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-29	101.2	1459	1491
UBD/Beta-Prp	2.90e-76	256.5	1327	1632

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH ++v+ + f +d  + ++++ Dg+++vW+l 
   Q: 1459 GHRSKVNEVVFsPDeSYCATCGEDGSVRVWSLA 1491
           8***********999****************86 PP

UBD/Beta-Prp

   S: 55   vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.......... 131
            t++++   + +l  gs+ + ++vwd  +g c+ ++++ + ++ +l  s   ++lvsGs+ r +r+w +    +l+           
   Q: 1327 LTSLCYGAAR-LLYCGSSTGQVCVWDTGAGRCFLVWEADDGEIGLLVCSG--SRLVSGSNTRRLRLWAVGAVPELQYkgssarstsv 1410
           4455555554.555555555555555555555555555555555554444..55555555555555555555555445555555555 PP
   S: 132  .............................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllr 173
                                                        + sgh++ vn vv++pd++++++++ D+ vr+W+l++++l+ 
   Q: 1411 fmereltldgaivsasfdsgmdmgvvgttagtlwyiswtegtstrLISGHRSKVNEVVFSPDESYCATCGEDGSVRVWSLASMELVV 1497
           55555555555555555555555555555555555555555555599**************************************** PP
   S: 174  tltgghtdsvyslsfdsng......kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsg 254
           +++   ++s  +l++++ +      +++v+g  dgt+++++++++ +  +++ h++  + ++fs +++ ++sg +Dg + +   r g
   Q: 1498 QFQV-LNQSCLCLAWSPPScghpeqQQVVAGYSDGTLRVFSISRTAMELKMHPHRSALTAIAFSTDGQTILSGDKDGLVAVSRPRVG 1583
           **98.*********87777777777*********************************************************99*** PP
   S: 255  dllktlqlhn...ssvisvav.....lsfgdnvl.vlgsedskvniwkl 294
            + ++l  h+    svi +++     l++++  l +++sed++v +w+ 
   Q: 1584 MTFRVLRDHQgapISVIQSTYkeyvdLGVEGEDLwLAVSEDQRVSVWAS 1632
           ********99655444444446665555555544377788*******85 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

DKTLKGSVYL IRGSVSANNY LQLPRTSTQS LGLTGRYLYV LFRPLPAKRF VIHLDVTTQD 60
SQVIRVSFSN FFKEFKSSAT WLQFPFVFET RTPRRVLAGM APPGACWTFL QLDLHDILLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACAAAACCC TGAAGGGCTC CGTATATCTC ATCCGGGGAT CTGTCTCTGC CAATAACTAC 60
CTCCAGCTTC CCAGAACCAG CACCCAGTCC CTGGGGCTAA CTGGGCGGTA CCTATATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR007714--CFA20/WDR90/C3orf67
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR030466--WDR90

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF05018--DUF667
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001801	Ailuropoda melanoleuca	66.28	0.00e+00	2275.00
IUUC-Apl-003387	Anas platyrhynchos	54.93	0.00e+00	1758.00
IUUC-Aca-005235	Anolis carolinensis	51.57	0.00e+00	1548.00
IUUC-Ame-011595	Astyanax mexicanus	52.15	0.00e+00	702.00
IUUC-Bta-012328	Bos taurus	64.93	0.00e+00	2155.00
IUUC-Cja-019058	Callithrix jacchus	63.58	0.00e+00	1170.00
IUUC-Cfa-020934	Canis familiaris	64.12	0.00e+00	2070.00
IUUC-Cre-022928	Chlamydomonas reinhardtii	28.40	5.00e-59	224.00
IUUC-Csa-023022	Chlorocebus sabaeus	68.59	0.00e+00	2262.00
IUUC-Cin-025133	Ciona intestinalis	35.12	0.00e+00	1114.00
IUUC-Csv-025816	Ciona savignyi	35.28	0.00e+00	1033.00
IUUC-Dre-028823	Danio rerio	45.22	0.00e+00	1516.00
IUUC-Dno-029211	Dasypus novemcinctus	63.55	0.00e+00	1462.00
IUUC-Dor-030211	Dipodomys ordii	71.31	0.00e+00	1379.00
IUUC-Ete-032363	Echinops telfairi	56.17	0.00e+00	888.00
IUUC-Eca-034296	Equus caballus	67.56	0.00e+00	2253.00
IUUC-Eeu-035226	Erinaceus europaeus	53.32	0.00e+00	800.00
IUUC-Fca-035384	Felis catus	67.21	0.00e+00	2266.00
IUUC-Fal-037660	Ficedula albicollis	52.37	0.00e+00	904.00
IUUC-Gga-040666	Gallus gallus	58.08	0.00e+00	1368.00
IUUC-Gac-041358	Gasterosteus aculeatus	45.46	0.00e+00	1489.00
IUUC-Ggo-045121	Gorilla gorilla	67.85	0.00e+00	2276.00
IUUC-Hsa-046289	Homo sapiens	67.85	0.00e+00	2230.00
IUUC-Itr-048485	Ictidomys tridecemlineatus	71.56	0.00e+00	2378.00
IUUC-Lch-050009	Latimeria chalumnae	48.85	0.00e+00	1590.00
IUUC-Loc-052629	Lepisosteus oculatus	49.63	1.00e-168	587.00
IUUC-Mcc-055834	Macaca mulatta	58.42	0.00e+00	1796.00
IUUC-Meu-056162	Macropus eugenii	58.17	0.00e+00	766.00
IUUC-Mga-060167	Meleagris gallopavo	53.04	0.00e+00	1635.00
IUUC-Mmr-060761	Microcebus murinus	77.45	9.00e-141	492.00
IUUC-Mdo-061886	Monodelphis domestica	57.12	0.00e+00	2084.00
IUUC-Mmu-063652	Mus musculus	69.86	0.00e+00	2470.00
IUUC-Mlu-068141	Myotis lucifugus	65.73	0.00e+00	2195.00
IUUC-Nle-069133	Nomascus leucogenys	63.34	0.00e+00	1395.00
IUUC-Ont-072496	Oreochromis niloticus	46.77	0.00e+00	1576.00
IUUC-Oan-072833	Ornithorhynchus anatinus	51.59	0.00e+00	1652.00
IUUC-Ola-086564	Oryzias latipes	44.79	0.00e+00	1517.00
IUUC-Oga-088919	Otolemur garnettii	66.87	0.00e+00	2238.00
IUUC-Oar-089946	Ovis aries	63.55	0.00e+00	1138.00
IUUC-Ptr-090755	Pan troglodytes	67.73	0.00e+00	1933.00
IUUC-Pan-092054	Papio anubis	68.49	0.00e+00	2274.00
IUUC-Psi-093467	Pelodiscus sinensis	56.13	0.00e+00	1971.00
IUUC-Pma-094553	Petromyzon marinus	43.82	0.00e+00	747.00
IUUC-Pfo-096849	Poecilia formosa	43.98	0.00e+00	1367.00
IUUC-Pab-098320	Pongo abelii	67.32	0.00e+00	2028.00
IUUC-Pca-100172	Procavia capensis	56.02	0.00e+00	1036.00
IUUC-Pva-102772	Pteropus vampyrus	65.51	0.00e+00	1211.00
IUUC-Rno-105046	Rattus norvegicus	70.84	0.00e+00	2506.00
IUUC-Sha-107094	Sarcophilus harrisii	57.03	0.00e+00	2069.00
IUUC-Ssc-116257	Sus scrofa	63.67	0.00e+00	2050.00
IUUC-Tgu-117323	Taeniopygia guttata	52.21	0.00e+00	1491.00
IUUC-Tru-118717	Takifugu rubripes	44.92	0.00e+00	1446.00
IUUC-Tni-120108	Tetraodon nigroviridis	44.90	0.00e+00	823.00
IUUC-Ttr-128378	Tursiops truncatus	74.81	0.00e+00	967.00
IUUC-Xtr-131760	Xenopus tropicalis	48.80	0.00e+00	1590.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence