iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050009

Ensembl Protein ID

ENSLACP00000002441.1

UniProt Accession

H2ZYH0; H2ZYH0_LATCH

Genbank Protein ID

ENSLACP00000002441

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01243525

Gene Name

WDR90

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000002179.1	ENSLACT00000002461.1	ENSLACP00000002441.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-40	135.3	1527	1558
UBD/Beta-Prp	4.00e-94	315.4	538	842

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v+ + f +d +++++++ Dg+++vW l
   Q: 1527 GHKNKVNEVVFsPDkCHFATCAEDGSVRVWTL 1558
           8***********99****************76 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkl.....................lrslsgheae............................ 54
           +++f  +++  ++++ ++ i++w+v++g+l                              +                            
   Q: 538  KIAF--FDDTRMVSCGRDNIRLWRVRSGSLrscpvnlgeyhtleftdvafeE--------Ghlpdrepedrllfacsksghilevdykn 616
           4667..555556778899************8888887776666666644442........04444666699999999999999999999 PP
   S: 55   ................................vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvs 111
                                           +++++ s+   + +tgs+D+ +++w+l+ +  +   + he  v +++++p+g k+++
   Q: 617  vvlknvrrllpsqlkhsqrrekqtfksgpgiaINSISVSSA--FCATGSDDGYLRLWPLDFSAVFLEAE-HEGAVSLVNICPDGLKVLA 702
           9999999999999999999***********88888888888..9****************999999999.**************99999 PP
   S: 112  GshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsl 200
           ++    +   ++ ++     + + h++++ + ++++  + l++ s D+t+r+Wdl++++ l+++t   ++    l+f+++ + ++ g  
   Q: 703  ATTTGNLGYLEIASRGYTT-LMRSHTDSILGFSSDGIRRHLATVSQDGTIRIWDLNSMQQLYDFTA-LDETPCTLAFHPTLQVFACGFS 789
           999******9999999998.99******************************************99.555556689************* PP
   S: 201  dgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs 253
            g v+++++ ++  + + + h+  v+ ++fs+++++++s++s gs+ ++++  
   Q: 790  SGVVRVFNVAKSALLAEHKQHRGGVTGLAFSQDGDYMYSAGSLGSLALYNSAE 842
           **********************************************9999765 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

LFSVWQHPYV NVFKHFKVEE WKKSTKEGDV TTVMPFSLLC WHQPLHFPPS LFLLIPFSLM 60
RSPLCWHWPI LHFPGMSLLT HTPLSRNDSQ VIRVSFSNLF KEFKSTATWL QFPFICGAAK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTTTTCAG TGTGGCAGCA TCCCTATGTC AATGTCTTCA AACACTTCAA GGTTGAAGAA 60
TGGAAGAAAT CAACAAAGGA GGGAGACGTG ACGACTGTCA TGGTGAGATG TTGTATTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR007714--CFA20/WDR90/C3orf67
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR030466--WDR90

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF05018--DUF667
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001801	Ailuropoda melanoleuca	47.70	0.00e+00	912.00
IUUC-Apl-003387	Anas platyrhynchos	59.10	0.00e+00	1930.00
IUUC-Aca-005235	Anolis carolinensis	59.32	0.00e+00	1901.00
IUUC-Ame-011595	Astyanax mexicanus	56.75	0.00e+00	2045.00
IUUC-Bta-012328	Bos taurus	48.44	0.00e+00	1611.00
IUUC-Cja-019058	Callithrix jacchus	50.63	0.00e+00	821.00
IUUC-Cfa-020934	Canis familiaris	47.54	0.00e+00	1565.00
IUUC-Cpo-022025	Cavia porcellus	49.02	0.00e+00	1621.00
IUUC-Cre-022928	Chlamydomonas reinhardtii	30.49	2.00e-80	295.00
IUUC-Csa-023022	Chlorocebus sabaeus	48.47	0.00e+00	1641.00
IUUC-Cin-025133	Ciona intestinalis	38.95	0.00e+00	1332.00
IUUC-Csv-025816	Ciona savignyi	37.27	0.00e+00	1136.00
IUUC-Dre-028823	Danio rerio	53.77	0.00e+00	1958.00
IUUC-Dno-029211	Dasypus novemcinctus	57.37	0.00e+00	751.00
IUUC-Dor-030211	Dipodomys ordii	48.33	0.00e+00	898.00
IUUC-Ete-032363	Echinops telfairi	48.20	2.00e-106	380.00
IUUC-Eca-034296	Equus caballus	48.53	0.00e+00	1596.00
IUUC-Eeu-035226	Erinaceus europaeus	44.75	8.00e-126	444.00
IUUC-Fca-035384	Felis catus	49.19	0.00e+00	1691.00
IUUC-Fal-037660	Ficedula albicollis	56.37	0.00e+00	1928.00
IUUC-Gga-040666	Gallus gallus	59.92	0.00e+00	1451.00
IUUC-Gac-041358	Gasterosteus aculeatus	55.62	0.00e+00	1978.00
IUUC-Ggo-045121	Gorilla gorilla	47.60	0.00e+00	932.00
IUUC-Hsa-046289	Homo sapiens	48.52	0.00e+00	1621.00
IUUC-Itr-048485	Ictidomys tridecemlineatus	47.83	0.00e+00	1561.00
IUUC-Loc-052629	Lepisosteus oculatus	61.20	0.00e+00	1175.00
IUUC-Mcc-055834	Macaca mulatta	44.66	0.00e+00	840.00
IUUC-Meu-056162	Macropus eugenii	53.46	0.00e+00	711.00
IUUC-Mga-060167	Meleagris gallopavo	57.57	0.00e+00	1848.00
IUUC-Mmr-060761	Microcebus murinus	56.17	7.00e-101	360.00
IUUC-Mdo-061886	Monodelphis domestica	57.81	0.00e+00	2085.00
IUUC-Mmu-063652	Mus musculus	48.80	0.00e+00	1712.00
IUUC-Mlu-068141	Myotis lucifugus	50.35	0.00e+00	1719.00
IUUC-Nle-069133	Nomascus leucogenys	44.27	0.00e+00	999.00
IUUC-Ont-072496	Oreochromis niloticus	56.61	0.00e+00	2123.00
IUUC-Oan-072833	Ornithorhynchus anatinus	50.79	0.00e+00	907.00
IUUC-Ola-086564	Oryzias latipes	52.14	0.00e+00	1865.00
IUUC-Oga-088919	Otolemur garnettii	49.46	0.00e+00	1440.00
IUUC-Oar-089946	Ovis aries	55.29	0.00e+00	745.00
IUUC-Ptr-090755	Pan troglodytes	54.55	0.00e+00	749.00
IUUC-Pan-092054	Papio anubis	48.33	0.00e+00	1642.00
IUUC-Psi-093467	Pelodiscus sinensis	63.63	0.00e+00	2264.00
IUUC-Pma-094573	Petromyzon marinus	45.51	0.00e+00	1591.00
IUUC-Pfo-096849	Poecilia formosa	52.82	0.00e+00	1826.00
IUUC-Pab-098320	Pongo abelii	47.60	0.00e+00	916.00
IUUC-Pca-100172	Procavia capensis	46.01	0.00e+00	858.00
IUUC-Pva-102772	Pteropus vampyrus	50.29	0.00e+00	917.00
IUUC-Rno-105046	Rattus norvegicus	49.23	0.00e+00	1730.00
IUUC-Sha-107094	Sarcophilus harrisii	57.80	0.00e+00	2128.00
IUUC-Ssc-116257	Sus scrofa	47.07	0.00e+00	843.00
IUUC-Tgu-117323	Taeniopygia guttata	61.71	0.00e+00	897.00
IUUC-Tru-118717	Takifugu rubripes	51.87	0.00e+00	1805.00
IUUC-Tni-120108	Tetraodon nigroviridis	51.76	0.00e+00	1771.00
IUUC-Ttr-128378	Tursiops truncatus	57.25	0.00e+00	760.00
IUUC-Xtr-131760	Xenopus tropicalis	57.27	0.00e+00	2055.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence