iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037184

Ensembl Protein ID

ENSFALP00000007414.1

UniProt Accession

U3JXB0; U3JXB0_FICAL

Genbank Protein ID

ENSFALP00000007414

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000183

Gene Name

WSB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000007105.1	ENSFALT00000007446.1	ENSFALP00000007414.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.40e-14	52.2	239	286
E3 adaptor/Cullin RING/DCX/DWD	2.30e-37	125.0	33	67
UBD/Beta-Prp	3.10e-46	157.6	7	243

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyed 51
           ++++w++++   SL+hLCR+a r +l+++++    +LP+P++Lk++L y++
   Q: 239  HVQFWTAPRVLSSLKHLCRKALRTFLTTYQV---LALPIPRKLKEFLTYRT 286
           689****************************...***************86 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrt 32
           gH+d v++l+f  ++ ++lvs+s+D+t++vWDl++
   Q: 33   GHQDVVRDLSFapNGsPILVSASRDKTLRVWDLSR 67
           8***********7558****************976 PP

UBD/Beta-Prp

   S: 24   llatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfspsgdklv 110
           +latg  dg ikvw+v+tg ll sl gh++ v++++f p+g+ ilv++s+D+t++vwdls +g +v++l+gh + v+++s+sp+ + l 
   Q: 7    VLATGLNDGQIKVWEVQTGHLLFSLLGHQDVVRDLSFAPNGSpILVSASRDKTLRVWDLSrDGRQVQVLSGHVQWVYCCSISPDCSMLC 95
           59***************************************99****************999*********************99**** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tgghtdsvysls 187
           s+   + + +w +++++ ++  l+gh+++v +  ++pd+ llv++s+D +v +Wd  tg+ lrtl            ++ ht+s +s+ 
   Q: 96   SAAGEKSALLWSMRSYTLIR-RLEGHQSSVVSCDFSPDSALLVTASYDACVIMWDPYTGEQLRTLrhvplysmldssSEIHTSSLRSVC 183
           ********************.*******************************************************9889********* PP
   S: 188  fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           f+++g +l+++++d+ +++w l+  +      +  +n ++   +p++ ++++g+ Dg +++W
   Q: 184  FSPEGLYLATVADDRLLRIWALELRS--PVAFAPMTNGLCCMYFPHGGFIATGTRDGHVQFW 243
           **********************9665..34556666666666667***************** PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MGLPCLVLAT GLNDGQIKVW EVQTGHLLFS LLGHQDVVRD LSFAPNGSPI LVSASRDKTL 60
RVWDLSRDGR QVQVLSGHVQ WVYCCSISPD CSMLCSAAGE KSALLWSMRS YTLIRRLEGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGGGGACA CAGATCCTGC CTGTGCCATG GGGCTCCCCT GCCTGGTCCT GGCCACTGGG 60
CTCAACGACG GGCAGATCAA GGTGTGGGAG GTGCAGACAG GTGAGCAGGA GCTCCCATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002221	Ailuropoda melanoleuca	84.10	6.00e-142	496.00
IUUC-Apl-004107	Anas platyrhynchos	84.15	5.00e-129	453.00
IUUC-Aca-004354	Anolis carolinensis	78.87	2.00e-130	458.00
IUUC-Bta-012627	Bos taurus	84.45	4.00e-143	500.00
IUUC-Cja-018897	Callithrix jacchus	83.04	3.00e-139	488.00
IUUC-Cfa-020122	Canis familiaris	84.45	3.00e-142	497.00
IUUC-Cpo-022540	Cavia porcellus	84.81	3.00e-143	501.00
IUUC-Csa-023719	Chlorocebus sabaeus	84.10	5.00e-142	497.00
IUUC-Cho-024367	Choloepus hoffmanni	84.10	9.00e-143	499.00
IUUC-Dno-029021	Dasypus novemcinctus	84.10	8.00e-142	496.00
IUUC-Dor-030321	Dipodomys ordii	84.45	6.00e-143	500.00
IUUC-Ete-032955	Echinops telfairi	85.11	3.00e-142	497.00
IUUC-Eca-033485	Equus caballus	84.45	3.00e-142	497.00
IUUC-Fca-035389	Felis catus	83.51	4.00e-142	497.00
IUUC-Gga-041014	Gallus gallus	94.76	4.00e-149	520.00
IUUC-Ggo-045585	Gorilla gorilla	84.45	1.00e-142	498.00
IUUC-Hsa-046344	Homo sapiens	84.45	1.00e-142	499.00
IUUC-Itr-049085	Ictidomys tridecemlineatus	84.21	4.00e-143	500.00
IUUC-Lch-050131	Latimeria chalumnae	73.33	3.00e-127	448.00
IUUC-Loc-052807	Lepisosteus oculatus	57.86	3.00e-93	335.00
IUUC-Laf-053528	Loxodonta africana	84.45	3.00e-142	497.00
IUUC-Mcc-055665	Macaca mulatta	84.45	1.00e-142	499.00
IUUC-Meu-056054	Macropus eugenii	80.99	2.00e-132	464.00
IUUC-Mga-059326	Meleagris gallopavo	95.42	5.00e-159	553.00
IUUC-Mmr-060815	Microcebus murinus	83.16	5.00e-143	500.00
IUUC-Mdo-062000	Monodelphis domestica	86.57	6.00e-146	509.00
IUUC-Mmu-063927	Mus musculus	84.81	4.00e-143	500.00
IUUC-Mpu-065726	Mustela putorius furo	83.51	5.00e-142	497.00
IUUC-Nle-069680	Nomascus leucogenys	83.86	1.00e-142	498.00
IUUC-Opr-070356	Ochotona princeps	84.81	4.00e-143	500.00
IUUC-Oan-073647	Ornithorhynchus anatinus	82.12	6.00e-135	473.00
IUUC-Ocu-073973	Oryctolagus cuniculus	84.81	3.00e-143	501.00
IUUC-Oga-088797	Otolemur garnettii	83.80	5.00e-141	493.00
IUUC-Oar-089187	Ovis aries	84.45	6.00e-143	499.00
IUUC-Ptr-091317	Pan troglodytes	84.45	2.00e-142	498.00
IUUC-Pan-092694	Papio anubis	76.90	5.00e-118	417.00
IUUC-Psi-093392	Pelodiscus sinensis	86.88	5.00e-144	503.00
IUUC-Pab-098145	Pongo abelii	84.45	2.00e-142	498.00
IUUC-Pca-100454	Procavia capensis	73.50	1.00e-117	416.00
IUUC-Pva-102986	Pteropus vampyrus	73.50	3.00e-118	417.00
IUUC-Rno-104931	Rattus norvegicus	84.45	3.00e-142	497.00
IUUC-Sha-106476	Sarcophilus harrisii	85.87	1.00e-144	505.00
IUUC-Ssc-115643	Sus scrofa	84.45	2.00e-142	498.00
IUUC-Tgu-117522	Taeniopygia guttata	73.01	7.00e-107	380.00
IUUC-Tsy-119301	Tarsius syrichta	84.10	2.00e-142	498.00
IUUC-Ttr-128683	Tursiops truncatus	84.45	1.00e-142	499.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence