iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034144

UUCD1 version

UUC-EqC-00382

Ensembl Protein ID

ENSECAP00000018265.1

UniProt Accession

F6WDM0; F6WDM0_HORSE

Protein Name

Uncharacterized protein

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000020479.1	ENSECAT00000022126.1	ENSECAP00000018265.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-42	140.0	50	87
UBD/Beta-Prp	1.30e-66	225.0	44	253

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd..tllvsGsdDgtikvWDlrtg 33
           gHt++v+++ f   ++  +l +++sdDgt+k+WD+ t 
   Q: 50   GHTERVSGFTFshhPGqyNLCATSSDDGTVKIWDVETK 87
           8************9666799**************9875 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqc 128
           ++ +l gh++ v+  +fs++     + +t+s+D+t+k+wd++t + v     h++++ +l++sp  +d +vsG++  ++ ++ l+ +  
   Q: 44   VIGELVGHTERVSGFTFSHHPGqynLCATSSDDGTVKIWDVETKTVVTEHALHQHTISALHWSPrVKDLIVSGDEKGVVFCYWLNRNDS 132
           67899**************965677***************************************666**************96666666 PP
   S: 129  leetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...........fdsng............ 192
            +  ls++ +++ c++ +p + +l++ G +D++v + d+ k g+++++l+g h+d ++s++           +                
   Q: 133  QQ--LSVEPRTIFCLTCSPHDeDLVAIGYKDGIVVIIDIsKKGEVIHRLRG-HDDEIHSIAwcplpgedclsI---Nqeenseepeipn 215
           65..9************99999*****************999********9.*********777666666541...0456778899999 PP
   S: 193  ............kelvsgsldgtvklwdlqtgecvrtl 218
                        +l++gs+d+t+++w++++g+ v++l
   Q: 216  gkviaqtpvtkgCYLATGSKDQTIRIWSCSRGRGVMIL 253
           999999999999******************99877765 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

XNWYCARCSD AVHGGLFGFR GTSVFLVRVG PGAGAIPGTP PSRVIGELVG HTERVSGFTF 60
SHHPGQYNLC ATSSDDGTVK IWDVETKTVV TEHALHQHTI SALHWSPRVK DLIVSGDEKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NCTAACTGGT ACTGCGCACG ATGCAGCGAT GCCGTGCACG GGGGGCTCTT CGGCTTTCGC 60
GGCGCGGAAC CTCCGTTTTC CTTGTCCGCG TGGGCCCAGG CGCGGGCGCG ATCCCTGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	89.07	0.00e+00	2601.00
IUUC-Apl-003586	Anas platyrhynchos	62.03	0.00e+00	1638.00
IUUC-Aca-004956	Anolis carolinensis	62.14	0.00e+00	1841.00
IUUC-Ame-010753	Astyanax mexicanus	49.93	0.00e+00	1459.00
IUUC-Bta-012315	Bos taurus	88.35	0.00e+00	2609.00
IUUC-Cja-019334	Callithrix jacchus	86.86	0.00e+00	2610.00
IUUC-Cfa-021254	Canis familiaris	89.32	0.00e+00	2675.00
IUUC-Cpo-021984	Cavia porcellus	81.06	0.00e+00	2296.00
IUUC-Csa-023650	Chlorocebus sabaeus	87.62	0.00e+00	2589.00
IUUC-Cho-024860	Choloepus hoffmanni	82.27	0.00e+00	2353.00
IUUC-Cin-025778	Ciona intestinalis	41.85	3.00e-156	546.00
IUUC-Csv-026313	Ciona savignyi	41.63	3.00e-163	568.00
IUUC-Dre-028096	Danio rerio	51.07	0.00e+00	1442.00
IUUC-Dno-029799	Dasypus novemcinctus	88.66	0.00e+00	2201.00
IUUC-Dor-030885	Dipodomys ordii	73.96	0.00e+00	1047.00
IUUC-Ete-032918	Echinops telfairi	79.91	0.00e+00	2352.00
IUUC-Eeu-034843	Erinaceus europaeus	78.99	0.00e+00	1810.00
IUUC-Fca-035948	Felis catus	88.55	0.00e+00	2595.00
IUUC-Fal-037303	Ficedula albicollis	61.29	0.00e+00	1790.00
IUUC-Gmo-039591	Gadus morhua	52.70	0.00e+00	820.00
IUUC-Gga-040570	Gallus gallus	61.59	0.00e+00	1640.00
IUUC-Gac-042646	Gasterosteus aculeatus	47.99	0.00e+00	1334.00
IUUC-Ggo-045605	Gorilla gorilla	80.62	0.00e+00	1816.00
IUUC-Hsa-046122	Homo sapiens	88.30	0.00e+00	2593.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	89.31	0.00e+00	2247.00
IUUC-Lch-050489	Latimeria chalumnae	50.86	0.00e+00	872.00
IUUC-Loc-052259	Lepisosteus oculatus	50.93	0.00e+00	1427.00
IUUC-Laf-053338	Loxodonta africana	86.87	0.00e+00	2542.00
IUUC-Mcc-055442	Macaca mulatta	87.68	0.00e+00	2588.00
IUUC-Meu-056245	Macropus eugenii	81.05	0.00e+00	823.00
IUUC-Mga-060202	Meleagris gallopavo	62.43	0.00e+00	1698.00
IUUC-Mmr-061730	Microcebus murinus	87.11	0.00e+00	2552.00
IUUC-Mdo-062880	Monodelphis domestica	73.12	0.00e+00	2167.00
IUUC-Mmu-063930	Mus musculus	80.60	0.00e+00	2268.00
IUUC-Mpu-066605	Mustela putorius furo	88.87	0.00e+00	2617.00
IUUC-Mlu-067765	Myotis lucifugus	89.29	0.00e+00	2658.00
IUUC-Nle-069183	Nomascus leucogenys	87.64	0.00e+00	2556.00
IUUC-Opr-070659	Ochotona princeps	74.49	0.00e+00	1144.00
IUUC-Ont-072356	Oreochromis niloticus	61.53	0.00e+00	993.00
IUUC-Oan-073056	Ornithorhynchus anatinus	71.34	0.00e+00	1997.00
IUUC-Ocu-073881	Oryctolagus cuniculus	86.76	0.00e+00	2595.00
IUUC-Ola-087120	Oryzias latipes	55.50	1.00e-60	225.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.43	1.00e-31	132.00
IUUC-Oga-088343	Otolemur garnettii	86.98	0.00e+00	2576.00
IUUC-Oar-089257	Ovis aries	88.73	0.00e+00	2647.00
IUUC-Ptr-090497	Pan troglodytes	88.10	0.00e+00	2559.00
IUUC-Pan-092638	Papio anubis	87.50	0.00e+00	2578.00
IUUC-Psi-093096	Pelodiscus sinensis	65.11	0.00e+00	1635.00
IUUC-Pma-094571	Petromyzon marinus	43.83	2.00e-84	305.00
IUUC-Pfo-096348	Poecilia formosa	61.07	0.00e+00	954.00
IUUC-Pab-098153	Pongo abelii	87.23	0.00e+00	2602.00
IUUC-Pca-100957	Procavia capensis	79.77	0.00e+00	2350.00
IUUC-Pva-102439	Pteropus vampyrus	89.99	0.00e+00	2660.00
IUUC-Rno-105891	Rattus norvegicus	81.12	0.00e+00	2258.00
IUUC-Sha-107181	Sarcophilus harrisii	73.67	0.00e+00	2088.00
IUUC-Ssc-115413	Sus scrofa	88.28	0.00e+00	2649.00
IUUC-Tgu-117082	Taeniopygia guttata	62.22	0.00e+00	1764.00
IUUC-Tru-118491	Takifugu rubripes	59.60	0.00e+00	941.00
IUUC-Tsy-119629	Tarsius syrichta	94.46	8.00e-168	585.00
IUUC-Tni-120240	Tetraodon nigroviridis	59.47	0.00e+00	936.00
IUUC-Tbe-127673	Tupaia belangeri	75.77	0.00e+00	2066.00
IUUC-Ttr-128562	Tursiops truncatus	86.52	0.00e+00	2561.00
IUUC-Vpa-130596	Vicugna pacos	86.13	0.00e+00	1865.00
IUUC-Xtr-132469	Xenopus tropicalis	56.36	0.00e+00	1616.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence