iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000005092.1	ENSOANT00000008087.1	ENSOANP00000008085.1
ENSOANG00000005092.1	ENSOANT00000008088.1	ENSOANP00000008086.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-38	129.6	580	615
UBD/Beta-Prp	3.20e-64	217.2	2	209

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           gHt+++t+la+   +d++lvs+++Dgt +vWD+ + 
   Q: 580  GHTAKITSLAWsphHDGRLVSACYDGTAQVWDVLKE 615
           8***********8766****************8665 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkf..spdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcle 130
           l +l gh++ v+  +f  +p +++ +++s+D+t+k+wd++t + v+    h++++ +l++sp  +d +vsG++  +i ++ ++++  ++
   Q: 2    LGELVGHTERVSGFTFchHPGQQLCASSSDDGTVKIWDVETKTVVSEHALHQNTISALHWSPrVKDLIVSGDEKGIIICY-WNNRNDSQ 89
           56899999999998883355667***************************************666**************7.66666666 PP
   S: 131  etlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls............fdsng............. 192
             + ++ ++v c++ +p   +l++ G +D++v + d+ + g+++++l+g h+d ++s++            ++++              
   Q: 90   -HFFPEPRTVFCLTCSPHHeDLVAIGYKDGMVVIIDIsRKGDIVHRLRG-HDDEIHSIAwcpvlgeeglsrWQDENpeeqeisngekiq 176
           .6888888999999999999*****************999********9.*********888877777666444448888899999999 PP
   S: 193  .......kelvsgsldgtvklwdlqtgecvrtl 218
                   +l++gs+d+t+++w++++g+ v+t+
   Q: 177  qsavtkdCYLATGSKDQTIRIWSCSRGRGVMTM 209
           999999999****************99988876 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

VLGELVGHTE RVSGFTFCHH PGQQLCASSS DDGTVKIWDV ETKTVVSEHA LHQNTISALH 60
WSPRVKDLIV SGDEKGIIIC YWNNRNDSQH FFPEPRTVFC LTCSPHHEDL VAIGYKDGMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCTAGGGG AATTGGTAGG ACACACGGAA AGGGTTTCCG GCTTCACATT TTGTCATCAT 60
CCGGGACAGC AGCTCTGTGC CAGCAGCTCT GATGATGGAA CGGTGAAAAT CTGGGATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	71.02	0.00e+00	2011.00
IUUC-Apl-003586	Anas platyrhynchos	65.86	0.00e+00	1765.00
IUUC-Aca-004956	Anolis carolinensis	64.84	0.00e+00	1905.00
IUUC-Ame-010753	Astyanax mexicanus	52.75	0.00e+00	1476.00
IUUC-Bta-012315	Bos taurus	71.51	0.00e+00	2016.00
IUUC-Cja-019334	Callithrix jacchus	70.72	0.00e+00	2032.00
IUUC-Cfa-021254	Canis familiaris	71.55	0.00e+00	2048.00
IUUC-Cpo-021984	Cavia porcellus	67.88	0.00e+00	1881.00
IUUC-Csa-023650	Chlorocebus sabaeus	70.55	0.00e+00	2004.00
IUUC-Cho-024860	Choloepus hoffmanni	66.78	0.00e+00	1859.00
IUUC-Cin-025778	Ciona intestinalis	42.22	2.00e-152	532.00
IUUC-Csv-026313	Ciona savignyi	41.87	4.00e-156	544.00
IUUC-Dre-028096	Danio rerio	67.01	0.00e+00	1001.00
IUUC-Dno-029799	Dasypus novemcinctus	76.56	0.00e+00	1828.00
IUUC-Dor-030885	Dipodomys ordii	61.40	1.00e-140	494.00
IUUC-Dme-031744	Drosophila melanogaster	26.01	8.00e-14	72.80
IUUC-Ete-032918	Echinops telfairi	67.16	0.00e+00	1891.00
IUUC-Eca-034144	Equus caballus	71.29	0.00e+00	2030.00
IUUC-Eeu-034843	Erinaceus europaeus	66.94	0.00e+00	1493.00
IUUC-Fca-035948	Felis catus	70.60	0.00e+00	2011.00
IUUC-Fal-037303	Ficedula albicollis	64.86	0.00e+00	1885.00
IUUC-Gmo-039591	Gadus morhua	56.51	0.00e+00	830.00
IUUC-Gga-040570	Gallus gallus	65.37	0.00e+00	1751.00
IUUC-Gac-042646	Gasterosteus aculeatus	54.17	0.00e+00	1340.00
IUUC-Ggo-045605	Gorilla gorilla	67.40	0.00e+00	1475.00
IUUC-Hsa-046122	Homo sapiens	71.19	0.00e+00	2015.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	75.74	0.00e+00	1831.00
IUUC-Lch-050489	Latimeria chalumnae	49.13	0.00e+00	864.00
IUUC-Loc-052259	Lepisosteus oculatus	52.88	0.00e+00	1452.00
IUUC-Laf-053338	Loxodonta africana	71.48	0.00e+00	2005.00
IUUC-Mcc-055442	Macaca mulatta	71.16	0.00e+00	2008.00
IUUC-Meu-056245	Macropus eugenii	85.19	0.00e+00	800.00
IUUC-Mga-060202	Meleagris gallopavo	64.85	0.00e+00	1812.00
IUUC-Mmr-061730	Microcebus murinus	70.71	0.00e+00	2006.00
IUUC-Mdo-062880	Monodelphis domestica	76.72	0.00e+00	2212.00
IUUC-Mmu-063930	Mus musculus	68.73	0.00e+00	1907.00
IUUC-Mpu-066605	Mustela putorius furo	71.09	0.00e+00	2027.00
IUUC-Mlu-067765	Myotis lucifugus	70.72	0.00e+00	2055.00
IUUC-Nle-069183	Nomascus leucogenys	70.45	0.00e+00	1965.00
IUUC-Opr-070659	Ochotona princeps	65.04	0.00e+00	730.00
IUUC-Ont-072356	Oreochromis niloticus	64.89	0.00e+00	1001.00
IUUC-Ocu-073881	Oryctolagus cuniculus	70.88	0.00e+00	2080.00
IUUC-Ola-087120	Oryzias latipes	61.15	6.00e-59	219.00
IUUC-Olu-087648	Ostreococcus lucimarinus	26.05	2.00e-29	124.00
IUUC-Oga-088343	Otolemur garnettii	70.45	0.00e+00	2024.00
IUUC-Oar-089257	Ovis aries	71.81	0.00e+00	2051.00
IUUC-Ptr-090497	Pan troglodytes	71.06	0.00e+00	2016.00
IUUC-Pan-092638	Papio anubis	70.92	0.00e+00	1995.00
IUUC-Psi-093096	Pelodiscus sinensis	68.17	0.00e+00	1761.00
IUUC-Pma-094571	Petromyzon marinus	40.04	2.00e-76	279.00
IUUC-Pfo-096348	Poecilia formosa	64.92	0.00e+00	979.00
IUUC-Pab-098153	Pongo abelii	70.38	0.00e+00	2017.00
IUUC-Pca-100957	Procavia capensis	66.30	0.00e+00	1868.00
IUUC-Pva-102439	Pteropus vampyrus	71.03	0.00e+00	2053.00
IUUC-Rno-105891	Rattus norvegicus	68.22	0.00e+00	1891.00
IUUC-Sha-107181	Sarcophilus harrisii	76.58	0.00e+00	2168.00
IUUC-Ssc-115413	Sus scrofa	71.46	0.00e+00	2035.00
IUUC-Tgu-117082	Taeniopygia guttata	65.49	0.00e+00	1840.00
IUUC-Tru-118491	Takifugu rubripes	61.55	0.00e+00	931.00
IUUC-Tsy-119629	Tarsius syrichta	80.49	5.00e-143	501.00
IUUC-Tni-120240	Tetraodon nigroviridis	62.48	0.00e+00	934.00
IUUC-Tbe-127673	Tupaia belangeri	63.38	0.00e+00	1658.00
IUUC-Ttr-128562	Tursiops truncatus	68.25	0.00e+00	1937.00
IUUC-Vpa-130596	Vicugna pacos	73.14	0.00e+00	1515.00
IUUC-Xtr-132469	Xenopus tropicalis	56.97	0.00e+00	1647.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence