iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066453

Ensembl Protein ID

ENSMPUP00000007525.1

UniProt Accession

M3Y868; M3Y868_MUSPF

Genbank Protein ID

ENSMPUP00000007525

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01024781

Gene Name

POC1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007581.1	ENSMPUT00000007646.1	ENSMPUP00000007525.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.40e-55	180.7	143	178
UBD/Beta-Prp	5.50e-83	278.6	59	312

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           Ht +v+c +f +d +l+vs+s D+tik+WD++   +
   Q: 143  HTHWVRCAKFsPDgRLIVSCSEDKTIKIWDTTNKQC 178
           9**********999****************987665 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           hk+v+t+v+fsp+++lla++srd+t+++w  ++  + ++++ h+a+v++v+fs dg++l+t+seD+ ikvw++     +++l +h++ v
   Q: 59   HKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKSSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWNMFRQRFLYSLYRHTHWV 147
           899************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
           ++ +fsp+g  +vs s+d+ti++wd+ ++qc++  +s   g+ n v ++p+g +++s++ D tv++Wd++ +kll++ +  h + v+++
   Q: 148  RCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVN-NFSDSVGFANFVDFNPNGTCIASAGSDHTVKIWDIRVNKLLQHYQV-HSGGVNCV 234
           *********************************.*********************************************8.******** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW..dlrsgdllktlql 262
           sf+++g +l+++s dgt+k+ dl +g+ ++tl+ght +v  v fs+ +e++ sg++D ++ +W  + +  ++  ++++
   Q: 235  SFHPSGHYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFSSGGADAQVLLWrtNFDDLNCKDMIKR 312
           ***************************************************************998888888777765 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MASALEDPVL ERYFKGHKAA ITSVDFSPSG KQLATASWDT FLMLWNCKPQ ARAFRFVGHK 60
DVVTSVQFSP HGNLLASASR DRTVRLWIPD KRGKSSEFKA HTAPVRSVDF SADGQFLATA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCTCCG CCCTGGTAAG GAGGGGCTGG GGGGCGCCTC CCCGGAGCTG GTGTCGCGGG 60
CTGTGGCGCC AGGTCCGGGC AGCTTTCGCA CCTGGCGGGA GATGGAGGCG GCGTCCGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0008283--P:cell proliferation
GO:0060271--P:cilium assembly
GO:0001895--P:retina homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002219	Ailuropoda melanoleuca	94.85	0.00e+00	863.00
IUUC-Apl-004219	Anas platyrhynchos	62.64	2.00e-159	555.00
IUUC-Aca-005197	Anolis carolinensis	59.21	3.00e-167	581.00
IUUC-Ame-011000	Astyanax mexicanus	56.67	3.00e-157	548.00
IUUC-Bta-012706	Bos taurus	90.17	0.00e+00	880.00
IUUC-Cja-019185	Callithrix jacchus	83.30	0.00e+00	803.00
IUUC-Cfa-021274	Canis familiaris	94.30	0.00e+00	905.00
IUUC-Cpo-022351	Cavia porcellus	83.30	0.00e+00	824.00
IUUC-Csa-023032	Chlorocebus sabaeus	83.47	0.00e+00	803.00
IUUC-Cho-024508	Choloepus hoffmanni	79.32	0.00e+00	662.00
IUUC-Dre-028703	Danio rerio	57.05	2.00e-156	545.00
IUUC-Dno-028915	Dasypus novemcinctus	89.66	0.00e+00	820.00
IUUC-Dor-030306	Dipodomys ordii	74.16	0.00e+00	652.00
IUUC-Dme-032182	Drosophila melanogaster	46.84	1.00e-82	299.00
IUUC-Ete-032353	Echinops telfairi	74.51	0.00e+00	690.00
IUUC-Eca-034136	Equus caballus	90.13	0.00e+00	816.00
IUUC-Eeu-034611	Erinaceus europaeus	80.10	4.00e-180	624.00
IUUC-Fca-036205	Felis catus	91.76	0.00e+00	796.00
IUUC-Fal-036947	Ficedula albicollis	52.43	1.00e-134	473.00
IUUC-Gga-040847	Gallus gallus	61.02	7.00e-162	563.00
IUUC-Ggo-045194	Gorilla gorilla	88.10	0.00e+00	869.00
IUUC-Hsa-047026	Homo sapiens	88.10	0.00e+00	869.00
IUUC-Itr-048943	Ictidomys tridecemlineatus	85.46	0.00e+00	789.00
IUUC-Lch-050067	Latimeria chalumnae	59.83	7.00e-173	600.00
IUUC-Loc-052409	Lepisosteus oculatus	58.99	2.00e-164	571.00
IUUC-Laf-053428	Loxodonta africana	88.58	0.00e+00	853.00
IUUC-Mcc-054772	Macaca mulatta	88.52	0.00e+00	867.00
IUUC-Meu-056496	Macropus eugenii	74.53	2.00e-165	575.00
IUUC-Mga-059276	Meleagris gallopavo	58.86	4.00e-161	561.00
IUUC-Mmr-061525	Microcebus murinus	88.52	0.00e+00	872.00
IUUC-Mdo-062351	Monodelphis domestica	69.01	0.00e+00	719.00
IUUC-Mmu-063834	Mus musculus	81.63	0.00e+00	798.00
IUUC-Mlu-067909	Myotis lucifugus	87.89	0.00e+00	794.00
IUUC-Nle-069206	Nomascus leucogenys	87.89	0.00e+00	868.00
IUUC-Opr-070566	Ochotona princeps	75.32	0.00e+00	716.00
IUUC-Oan-073726	Ornithorhynchus anatinus	67.90	7.00e-173	599.00
IUUC-Ocu-074639	Oryctolagus cuniculus	88.94	0.00e+00	874.00
IUUC-Ola-086913	Oryzias latipes	52.84	2.00e-146	512.00
IUUC-Oga-088061	Otolemur garnettii	90.17	0.00e+00	669.00
IUUC-Oar-090228	Ovis aries	85.15	0.00e+00	867.00
IUUC-Ptr-091420	Pan troglodytes	88.10	0.00e+00	870.00
IUUC-Pan-092228	Papio anubis	88.31	0.00e+00	866.00
IUUC-Psi-093309	Pelodiscus sinensis	64.04	7.00e-169	586.00
IUUC-Pab-098109	Pongo abelii	88.31	0.00e+00	871.00
IUUC-Pca-101012	Procavia capensis	67.64	2.00e-179	622.00
IUUC-Pva-102712	Pteropus vampyrus	90.81	0.00e+00	878.00
IUUC-Rno-105260	Rattus norvegicus	81.42	0.00e+00	797.00
IUUC-Sar-113446	Sorex araneus	77.20	0.00e+00	758.00
IUUC-Ssc-115794	Sus scrofa	94.04	0.00e+00	724.00
IUUC-Tgu-116770	Taeniopygia guttata	53.68	2.00e-138	485.00
IUUC-Tru-117968	Takifugu rubripes	54.83	2.00e-145	508.00
IUUC-Tsy-119316	Tarsius syrichta	73.03	0.00e+00	649.00
IUUC-Tni-119953	Tetraodon nigroviridis	49.39	3.00e-128	451.00
IUUC-Tbe-128071	Tupaia belangeri	84.14	0.00e+00	744.00
IUUC-Ttr-129267	Tursiops truncatus	90.40	0.00e+00	878.00
IUUC-Vpa-130823	Vicugna pacos	82.92	3.00e-178	617.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence