iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000014711.1	ENSSHAT00000017452.1	ENSSHAP00000017307.1
ENSSHAG00000014711.1	ENSSHAT00000017453.1	ENSSHAP00000017308.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.20e-65	220.7	105	481
ULD/UDP/UBQ/UBQ_Other	1.30e-08	34.8	6	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+++l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 105  CGLTNLGNTCYMNATVQCIRSVPELKDALKR-YAGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekgd 191
           7******************************.****************************.99999******************99*** PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l+  +  +++e+      e  +++  + ++k+ksli++ F++++++++kc e +++  ++ + ++l
   Q: 192  qgQYLQQDANECWVQMMRVLQQKLEALEGDSVMET------ENASSSAAQAPTKKKSLIDQFFGVEFETTMKCTEAEEEEATKGKENQL 274
           999*********************66444444444......3444567789999**************************999988888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +     ++++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 275  QLSCFINQEV--KYLFTGLKLRLQEEITK-----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDV 356
           8888877754..58999999999999998.....58899999999******************************************** PP
   S: 262  spfcts..................peekqke.................................kkkYeLiavvvHsG.slssGHYvay 298
            + ct                   +     +                                 +  Y+L av+ H+G s+ssGHYv++
   Q: 357  YELCTPelqekmvsfrskfkdledK-----KvnqqpktfsksggaqkevkyepfsfpddigsnnCGYYDLQAVLTHQGrSSSSGHYVSW 440
           ******6666666666666555550.....0555556666666666666677777777777777************************* PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 441  VKRKQDEWIKFDDDKVSIVTPEDILRLSGggdwHIAYVLLY 481
           **************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           v vk+ + +  ++++n +++  ++K +++ ++g++p++q+ ++kG  L+dd +++++++k g+t++++ +
   Q: 6    VNVKWGKEKFDGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDD-DWGNLKIKSGMTLLMMGS 74
           7899999999999***********************************999.9**************965 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MPLFSVNVKW GKEKFDGVEL NTDEPPMVFK AQLFALTGVQ PARQKVMVKG GTLKDDDWGN 60
LKIKSGMTLL MMGSADALPE EPVARTVFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGCTCT TCTCAGGTGA GCTCCGCCCG GGGCCTCTTC CTTTAGCTTC CTTCCCCAGG 60
CAGCTCCCCG GGGCACTAGG CCTCCCTCGG GCGGAGGCAC CATCCGAGCC CGGCCTCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

shr:100916872

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	30.60	1.00e-63	237.00
IUUC-Aml-002053	Ailuropoda melanoleuca	93.50	0.00e+00	897.00
IUUC-Atr-002725	Amborella trichopoda	41.80	6.00e-101	360.00
IUUC-Apl-004031	Anas platyrhynchos	93.31	0.00e+00	917.00
IUUC-Aca-004361	Anolis carolinensis	92.12	0.00e+00	918.00
IUUC-Aly-006078	Arabidopsis lyrata	42.71	3.00e-112	398.00
IUUC-Ath-007623	Arabidopsis thaliana	42.69	2.00e-112	399.00
IUUC-Ago-007796	Ashbya gossypii	32.36	4.00e-56	212.00
IUUC-Acl-008258	Aspergillus clavatus	37.95	5.00e-65	241.00
IUUC-Afl-008732	Aspergillus flavus	34.81	1.00e-76	280.00
IUUC-Afu-008755	Aspergillus fumigatus	35.63	2.00e-81	296.00
IUUC-Ani-009148	Aspergillus nidulans	39.08	3.00e-70	259.00
IUUC-Ang-009878	Aspergillus niger	34.07	6.00e-71	261.00
IUUC-Aor-010239	Aspergillus oryzae	34.81	1.00e-76	280.00
IUUC-Ate-010243	Aspergillus terreus	34.05	2.00e-70	259.00
IUUC-Ame-011327	Astyanax mexicanus	52.10	4.00e-129	454.00
IUUC-Bgr-012231	Blumeria graminis	33.62	4.00e-70	258.00
IUUC-Bta-012553	Bos taurus	92.32	0.00e+00	913.00
IUUC-Bci-013606	Botrytis cinerea	39.07	6.00e-70	258.00
IUUC-Bdi-014567	Brachypodium distachyon	44.04	5.00e-113	401.00
IUUC-Bol-015565	Brassica oleracea	42.32	2.00e-114	405.00
IUUC-Bra-017501	Brassica rapa	42.12	7.00e-112	397.00
IUUC-Cel-018140	Caenorhabditis elegans	41.27	5.00e-101	361.00
IUUC-Cja-019516	Callithrix jacchus	92.14	0.00e+00	909.00
IUUC-Cfa-020808	Canis familiaris	93.54	0.00e+00	924.00
IUUC-Cpo-021688	Cavia porcellus	92.73	0.00e+00	910.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	37.35	2.00e-82	299.00
IUUC-Csa-023429	Chlorocebus sabaeus	92.90	0.00e+00	895.00
IUUC-Cho-024347	Choloepus hoffmanni	93.10	0.00e+00	917.00
IUUC-Cin-025198	Ciona intestinalis	53.66	6.00e-150	523.00
IUUC-Csv-026007	Ciona savignyi	52.50	4.00e-151	527.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	39.52	1.00e-63	237.00
IUUC-Cne-026963	Cryptococcus neoformans	35.17	2.00e-74	272.00
IUUC-Cme-027240	Cyanidioschyzon merolae	30.89	1.00e-59	223.00
IUUC-Dre-027647	Danio rerio	83.91	0.00e+00	832.00
IUUC-Dno-029967	Dasypus novemcinctus	92.73	0.00e+00	897.00
IUUC-Dor-030886	Dipodomys ordii	87.07	0.00e+00	733.00
IUUC-Dse-031466	Dothistroma septosporum	36.80	7.00e-56	211.00
IUUC-Dme-032079	Drosophila melanogaster	55.44	1.00e-156	546.00
IUUC-Ete-032351	Echinops telfairi	80.81	0.00e+00	788.00
IUUC-Eca-033461	Equus caballus	91.92	0.00e+00	937.00
IUUC-Eeu-035220	Erinaceus europaeus	70.84	0.00e+00	660.00
IUUC-Fca-036210	Felis catus	93.33	0.00e+00	923.00
IUUC-Fal-037528	Ficedula albicollis	92.91	0.00e+00	898.00
IUUC-Fox-037805	Fusarium oxysporum	40.10	1.00e-69	257.00
IUUC-Fso-038177	Fusarium solani	38.02	9.00e-66	244.00
IUUC-Gmo-038953	Gadus morhua	79.88	0.00e+00	763.00
IUUC-Ggr-039972	Gaeumannomyces graminis	34.92	2.00e-68	253.00
IUUC-Gga-040462	Gallus gallus	91.92	0.00e+00	913.00
IUUC-Gac-041312	Gasterosteus aculeatus	82.38	0.00e+00	812.00
IUUC-Gma-043255	Glycine max	42.49	9.00e-109	386.00
IUUC-Ggo-045458	Gorilla gorilla	77.17	0.00e+00	744.00
IUUC-Hsa-045706	Homo sapiens	92.93	0.00e+00	898.00
IUUC-Hvu-047821	Hordeum vulgare	47.22	2.00e-57	214.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	91.52	0.00e+00	906.00
IUUC-Lch-050464	Latimeria chalumnae	83.91	0.00e+00	832.00
IUUC-Lpe-051419	Leersia perrieri	42.09	3.00e-106	378.00
IUUC-Loc-052732	Lepisosteus oculatus	82.39	0.00e+00	839.00
IUUC-Lma-053177	Leptosphaeria maculans	40.64	6.00e-69	254.00
IUUC-Laf-053822	Loxodonta africana	93.31	0.00e+00	916.00
IUUC-Mcc-055893	Macaca mulatta	93.10	0.00e+00	896.00
IUUC-Meu-056307	Macropus eugenii	85.71	0.00e+00	820.00
IUUC-Mor-057171	Magnaporthe oryzae	38.34	4.00e-66	245.00
IUUC-Mpo-057415	Magnaporthe poae	40.77	7.00e-69	254.00
IUUC-Mtr-057901	Medicago truncatula	43.50	3.00e-111	395.00
IUUC-Mla-058897	Melampsora laricipopulina	40.32	5.00e-74	271.00
IUUC-Mga-060016	Meleagris gallopavo	92.29	0.00e+00	914.00
IUUC-Mvi-060562	Microbotryum violaceum	40.22	1.00e-64	240.00
IUUC-Mmr-060624	Microcebus murinus	92.53	0.00e+00	942.00
IUUC-Mdo-061809	Monodelphis domestica	96.37	0.00e+00	928.00
IUUC-Mmu-063869	Mus musculus	91.31	0.00e+00	901.00
IUUC-Mac-064876	Musa acuminata	40.20	7.00e-96	344.00
IUUC-Mpu-066480	Mustela putorius furo	93.54	0.00e+00	924.00
IUUC-Mlu-067866	Myotis lucifugus	91.72	0.00e+00	919.00
IUUC-Nfi-068393	Neosartorya fischeri	35.05	1.00e-78	286.00
IUUC-Ncr-068815	Neurospora crassa	35.96	2.00e-82	299.00
IUUC-Nle-070121	Nomascus leucogenys	92.13	2.00e-133	468.00
IUUC-Opr-070712	Ochotona princeps	74.19	9.00e-169	586.00
IUUC-Ont-071544	Oreochromis niloticus	82.11	0.00e+00	776.00
IUUC-Oan-073635	Ornithorhynchus anatinus	93.71	0.00e+00	768.00
IUUC-Ocu-074926	Oryctolagus cuniculus	91.31	0.00e+00	891.00
IUUC-Oba-075633	Oryza barthii	41.80	2.00e-105	375.00
IUUC-Obr-076423	Oryza brachyantha	42.54	7.00e-109	387.00
IUUC-Ogl-077913	Oryza glaberrima	41.68	2.00e-108	385.00
IUUC-Ogu-078435	Oryza glumaepatula	41.80	2.00e-105	375.00
IUUC-Oin-080072	Oryza indica	41.86	2.00e-105	376.00
IUUC-Olo-080535	Oryza longistaminata	39.12	2.00e-89	322.00
IUUC-Ome-081309	Oryza meridionalis	41.80	2.00e-105	375.00
IUUC-Oni-083113	Oryza nivara	41.80	2.00e-105	375.00
IUUC-Opu-083168	Oryza punctata	40.66	8.00e-100	357.00
IUUC-Oru-084253	Oryza rufipogon	41.80	2.00e-105	375.00
IUUC-Osa-085554	Oryza sativa	41.68	1.00e-108	386.00
IUUC-Ola-086998	Oryzias latipes	81.38	0.00e+00	803.00
IUUC-Olu-087818	Ostreococcus lucimarinus	36.82	3.00e-71	262.00
IUUC-Oga-088571	Otolemur garnettii	92.53	0.00e+00	915.00
IUUC-Oar-089526	Ovis aries	92.49	0.00e+00	909.00
IUUC-Ptr-091433	Pan troglodytes	93.10	0.00e+00	896.00
IUUC-Pan-091966	Papio anubis	92.90	0.00e+00	895.00
IUUC-Psi-093458	Pelodiscus sinensis	90.32	0.00e+00	848.00
IUUC-Pma-094343	Petromyzon marinus	68.75	5.00e-116	410.00
IUUC-Pno-095109	Phaeosphaeria nodorum	38.92	3.00e-65	242.00
IUUC-Ppa-095756	Physcomitrella patens	44.20	1.00e-111	396.00
IUUC-Pfo-096514	Poecilia formosa	83.13	0.00e+00	797.00
IUUC-Pab-098477	Pongo abelii	81.70	0.00e+00	712.00
IUUC-Pop-099221	Populus trichocarpa	41.07	1.00e-103	369.00
IUUC-Pca-100791	Procavia capensis	75.81	3.00e-170	590.00
IUUC-Ppe-101812	Prunus persica	42.05	2.00e-108	385.00
IUUC-Pva-102462	Pteropus vampyrus	87.67	0.00e+00	739.00
IUUC-Pgr-103623	Puccinia graminis	41.71	9.00e-73	267.00
IUUC-Ptt-103767	Puccinia triticina	40.18	4.00e-65	242.00
IUUC-Pte-104109	Pyrenophora teres	39.79	3.00e-68	252.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	40.42	2.00e-68	253.00
IUUC-Rno-105351	Rattus norvegicus	91.11	0.00e+00	869.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.43	4.00e-62	232.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	34.97	2.00e-78	286.00
IUUC-Spo-108174	Schizosaccharomyces pombe	37.94	1.00e-77	283.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	34.85	5.00e-83	301.00
IUUC-Smo-108805	Selaginella moellendorffii	44.15	3.00e-112	398.00
IUUC-Sit-110361	Setaria italica	43.51	1.00e-112	399.00
IUUC-Sly-110965	Solanum lycopersicum	40.94	3.00e-107	382.00
IUUC-Sar-113355	Sorex araneus	80.70	0.00e+00	647.00
IUUC-Sbi-114778	Sorghum bicolor	43.95	1.00e-112	399.00
IUUC-Sre-115011	Sporisorium reilianum	37.92	5.00e-60	225.00
IUUC-Ssc-116273	Sus scrofa	92.06	0.00e+00	897.00
IUUC-Tgu-117063	Taeniopygia guttata	92.29	0.00e+00	895.00
IUUC-Tru-118381	Takifugu rubripes	81.38	0.00e+00	796.00
IUUC-Tsy-119076	Tarsius syrichta	77.47	2.00e-112	399.00
IUUC-Tni-119941	Tetraodon nigroviridis	81.26	0.00e+00	782.00
IUUC-Tca-121246	Theobroma cacao	41.83	8.00e-109	387.00
IUUC-Tre-121969	Trichoderma reesei	38.11	5.00e-65	241.00
IUUC-Tvi-122543	Trichoderma virens	33.75	6.00e-74	271.00
IUUC-Tae-125484	Triticum aestivum	42.94	2.00e-109	389.00
IUUC-Tur-126128	Triticum urartu	32.69	2.00e-67	249.00
IUUC-Tbe-128030	Tupaia belangeri	85.48	0.00e+00	813.00
IUUC-Ttr-128701	Tursiops truncatus	91.29	0.00e+00	747.00
IUUC-Uma-129657	Ustilago maydis	37.54	1.00e-63	237.00
IUUC-Vda-129723	Verticillium dahliae	36.09	1.00e-56	213.00
IUUC-Vpa-130284	Vicugna pacos	65.44	4.00e-172	597.00
IUUC-Vvi-131037	Vitis vinifera	43.11	5.00e-109	387.00
IUUC-Xtr-132235	Xenopus tropicalis	86.75	0.00e+00	876.00
IUUC-Xma-133840	Xiphophorus maculatus	83.13	0.00e+00	823.00
IUUC-Yli-134453	Yarrowia lipolytica	37.10	1.00e-81	296.00
IUUC-Zma-135669	Zea mays	36.69	3.00e-93	335.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence