iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059863

UUCD1 version

UUC-MeG-00767

Ensembl Protein ID

ENSMGAP00000008614.1

UniProt Accession

G1N8H6; G1N8H6_MELGA

Protein Name

Uncharacterized protein

Gene Name

UBE2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000008406.2	ENSMGAT00000009414.1	ENSMGAP00000008614.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.00e-52	175.8	2	130

Active Site

Position(s)	Description	Evidence
76	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 7    kelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspa 95
           ++l++dpp g+s  p+++ ++++w+++i+Gpe+tp+e+g+Fkl ief+e+YP kPP+v+fl+k+fhPnvy++G++Cl+il+  ++Wsp+
   Q: 2    SRLQEDPPVGVSGAPSEN-NIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQ--NRWSPT 87
           689**************9.9************************************************************9..****** PP
   S: 96   lsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 88   YDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 130
           ****************************************996 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

ISRLQEDPPV GVSGAPSENN IMQWNAVIFG PEGTPFEDGT FKLVIEFSEE YPNKPPTVRF 60
LSKMFHPNVY ADGSICLDIL QNRWSPTYDV SSILTSIQSL LDEPNPNSPA NSQAAQLYQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCTAGAT TGCAAGAAGA CCCTCCTGTG GGTGTCAGTG GTGCACCATC TGAGAATAAT 60
ATAATGCAGT GGAATGCAGT TATATTTGGG TAAGAGTTTT TGCTCACTAT GAAGTCCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005657--C:replication fork
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0060070--P:canonical Wnt signaling pathway
GO:0051026--P:chiasma assembly
GO:0033522--P:histone H2A ubiquitination
GO:0070076--P:histone lysine demethylation
GO:0006344--P:maintenance of chromatin silencing
GO:0045141--P:meiotic telomere clustering
GO:0043066--P:negative regulation of apoptotic process
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0033128--P:negative regulation of histone phosphorylation
GO:0010845--P:positive regulation of reciprocal meiotic recombination
GO:0006301--P:postreplication repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0050821--P:protein stabilization
GO:0042493--P:response to drug
GO:0009411--P:response to UV
GO:0007288--P:sperm axoneme assembly
GO:0070193--P:synaptonemal complex organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001001	Aegilops tauschii	72.26	1.00e-60	224.00
IUUC-Aml-002120	Ailuropoda melanoleuca	98.57	3.00e-79	286.00
IUUC-Atr-002862	Amborella trichopoda	73.91	2.00e-62	230.00
IUUC-Apl-004063	Anas platyrhynchos	92.62	2.00e-76	276.00
IUUC-Aca-005001	Anolis carolinensis	97.86	5.00e-79	285.00
IUUC-Aly-005584	Arabidopsis lyrata	73.72	1.00e-61	227.00
IUUC-Ath-007149	Arabidopsis thaliana	73.72	1.00e-61	227.00
IUUC-Ago-007745	Ashbya gossypii	65.69	4.00e-54	203.00
IUUC-Acl-008139	Aspergillus clavatus	65.47	4.00e-56	209.00
IUUC-Afl-008551	Aspergillus flavus	65.47	6.00e-56	209.00
IUUC-Afu-008980	Aspergillus fumigatus	65.47	6.00e-56	209.00
IUUC-Ani-009470	Aspergillus nidulans	46.97	8.00e-26	109.00
IUUC-Ang-009554	Aspergillus niger	65.47	6.00e-56	209.00
IUUC-Aor-010242	Aspergillus oryzae	65.47	6.00e-56	209.00
IUUC-Ate-010390	Aspergillus terreus	65.47	6.00e-56	209.00
IUUC-Ame-011900	Astyanax mexicanus	94.96	1.00e-76	278.00
IUUC-Bgr-012039	Blumeria graminis	66.91	7.00e-56	208.00
IUUC-Bta-012840	Bos taurus	98.57	3.00e-79	286.00
IUUC-Bci-013919	Botrytis cinerea	65.71	8.00e-57	211.00
IUUC-Bdi-014475	Brachypodium distachyon	72.99	2.00e-61	227.00
IUUC-Bol-015726	Brassica oleracea	74.81	5.00e-61	228.00
IUUC-Bra-016643	Brassica rapa	74.81	1.00e-61	228.00
IUUC-Cel-018244	Caenorhabditis elegans	83.21	3.00e-68	250.00
IUUC-Cja-019737	Callithrix jacchus	98.57	3.00e-79	286.00
IUUC-Cfa-020244	Canis familiaris	98.57	3.00e-79	286.00
IUUC-Cpo-022192	Cavia porcellus	98.57	3.00e-79	286.00
IUUC-Cre-022822	Chlamydomonas reinhardtii	74.78	1.00e-49	188.00
IUUC-Csa-023430	Chlorocebus sabaeus	98.57	3.00e-79	286.00
IUUC-Cho-025061	Choloepus hoffmanni	94.50	5.00e-57	211.00
IUUC-Cin-025537	Ciona intestinalis	77.86	8.00e-53	198.00
IUUC-Csv-025846	Ciona savignyi	78.99	5.00e-58	215.00
IUUC-Cgl-026381	Colletotrichum gloeosporioides	65.47	1.00e-56	211.00
IUUC-Cne-026864	Cryptococcus neoformans	68.89	4.00e-57	213.00
IUUC-Cme-027284	Cyanidioschyzon merolae	63.04	7.00e-46	176.00
IUUC-Dre-027775	Danio rerio	95.65	7.00e-76	275.00
IUUC-Dno-029661	Dasypus novemcinctus	98.57	3.00e-79	286.00
IUUC-Dor-030452	Dipodomys ordii	100.00	3.00e-78	283.00
IUUC-Dse-031487	Dothistroma septosporum	65.47	3.00e-56	209.00
IUUC-Dme-031863	Drosophila melanogaster	83.45	7.00e-68	248.00
IUUC-Ete-032595	Echinops telfairi	95.00	2.00e-76	276.00
IUUC-Eca-033377	Equus caballus	98.57	3.00e-79	286.00
IUUC-Eeu-035191	Erinaceus europaeus	74.82	1.00e-52	198.00
IUUC-Fca-036336	Felis catus	98.57	3.00e-79	286.00
IUUC-Fal-037474	Ficedula albicollis	94.96	6.00e-65	238.00
IUUC-Fox-037808	Fusarium oxysporum	65.47	2.00e-56	210.00
IUUC-Fso-038232	Fusarium solani	65.47	3.00e-56	210.00
IUUC-Gmo-038517	Gadus morhua	94.24	9.00e-76	275.00
IUUC-Ggr-039875	Gaeumannomyces graminis	65.69	9.00e-56	208.00
IUUC-Gga-040494	Gallus gallus	98.57	3.00e-79	286.00
IUUC-Gac-042471	Gasterosteus aculeatus	93.57	1.00e-76	277.00
IUUC-Gma-043865	Glycine max	73.72	4.00e-62	229.00
IUUC-Ggo-044580	Gorilla gorilla	100.00	9.00e-80	288.00
IUUC-Hsa-046239	Homo sapiens	98.57	3.00e-79	286.00
IUUC-Hvu-047054	Hordeum vulgare	72.26	1.00e-60	224.00
IUUC-Itr-048960	Ictidomys tridecemlineatus	98.57	3.00e-79	286.00
IUUC-Kpa-049225	Komagataella pastoris	66.18	9.00e-54	202.00
IUUC-Lch-050283	Latimeria chalumnae	95.68	8.00e-77	278.00
IUUC-Lpe-051301	Leersia perrieri	73.72	1.00e-61	228.00
IUUC-Loc-051962	Lepisosteus oculatus	96.43	2.00e-77	280.00
IUUC-Lma-053214	Leptosphaeria maculans	44.53	1.00e-30	125.00
IUUC-Laf-053380	Loxodonta africana	98.57	3.00e-79	286.00
IUUC-Mcc-054819	Macaca mulatta	98.57	2.00e-79	287.00
IUUC-Meu-056103	Macropus eugenii	100.00	3.00e-78	283.00
IUUC-Mor-057087	Magnaporthe oryzae	67.16	1.00e-54	204.00
IUUC-Mpo-057498	Magnaporthe poae	65.69	1.00e-55	209.00
IUUC-Mtr-058305	Medicago truncatula	73.72	5.00e-62	229.00
IUUC-Mla-058876	Melampsora laricipopulina	72.26	1.00e-51	194.00
IUUC-Mvi-060330	Microbotryum violaceum	71.32	2.00e-50	190.00
IUUC-Mmr-060630	Microcebus murinus	98.57	3.00e-79	286.00
IUUC-Mdo-062676	Monodelphis domestica	98.57	3.00e-79	286.00
IUUC-Mmu-063491	Mus musculus	98.57	3.00e-79	286.00
IUUC-Mac-065641	Musa acuminata	73.72	2.00e-61	227.00
IUUC-Mpu-065803	Mustela putorius furo	98.57	3.00e-79	286.00
IUUC-Mlu-067147	Myotis lucifugus	98.57	3.00e-79	286.00
IUUC-Nfi-068580	Neosartorya fischeri	65.47	6.00e-56	209.00
IUUC-Ncr-068913	Neurospora crassa	65.47	1.00e-56	211.00
IUUC-Nle-070105	Nomascus leucogenys	98.57	3.00e-79	286.00
IUUC-Opr-070935	Ochotona princeps	98.57	3.00e-79	286.00
IUUC-Ont-071335	Oreochromis niloticus	93.57	2.00e-76	276.00
IUUC-Oan-072706	Ornithorhynchus anatinus	99.29	2.00e-79	286.00
IUUC-Ocu-074130	Oryctolagus cuniculus	98.57	3.00e-79	286.00
IUUC-Oba-075847	Oryza barthii	72.99	6.00e-61	226.00
IUUC-Obr-076713	Oryza brachyantha	73.72	1.00e-61	228.00
IUUC-Ogl-077116	Oryza glaberrima	73.72	1.00e-61	228.00
IUUC-Ogu-078696	Oryza glumaepatula	73.72	1.00e-61	228.00
IUUC-Oin-079099	Oryza indica	73.72	1.00e-61	228.00
IUUC-Olo-081018	Oryza longistaminata	61.44	3.00e-52	197.00
IUUC-Ome-081285	Oryza meridionalis	73.72	1.00e-61	228.00
IUUC-Oni-082088	Oryza nivara	73.72	1.00e-61	228.00
IUUC-Opu-083310	Oryza punctata	73.72	1.00e-61	228.00
IUUC-Oru-084449	Oryza rufipogon	73.72	1.00e-61	228.00
IUUC-Osa-085923	Oryza sativa	73.72	1.00e-61	228.00
IUUC-Ola-087160	Oryzias latipes	93.57	2.00e-76	276.00
IUUC-Olu-087830	Ostreococcus lucimarinus	77.04	5.00e-53	199.00
IUUC-Oga-088836	Otolemur garnettii	98.57	3.00e-79	286.00
IUUC-Oar-090141	Ovis aries	98.57	3.00e-79	286.00
IUUC-Ptr-091453	Pan troglodytes	98.57	3.00e-79	286.00
IUUC-Pan-092511	Papio anubis	98.57	3.00e-79	286.00
IUUC-Psi-093968	Pelodiscus sinensis	97.86	5.00e-79	285.00
IUUC-Pma-094239	Petromyzon marinus	93.53	2.00e-75	273.00
IUUC-Pno-094935	Phaeosphaeria nodorum	66.42	1.00e-56	211.00
IUUC-Ppa-095689	Physcomitrella patens	75.56	1.00e-52	198.00
IUUC-Pfo-096656	Poecilia formosa	93.53	1.00e-75	274.00
IUUC-Pab-098121	Pongo abelii	98.57	3.00e-79	286.00
IUUC-Pop-099517	Populus trichocarpa	73.72	6.00e-62	228.00
IUUC-Pca-100906	Procavia capensis	88.32	6.00e-68	248.00
IUUC-Ppe-101594	Prunus persica	73.72	1.00e-61	228.00
IUUC-Pva-102380	Pteropus vampyrus	92.81	7.00e-73	265.00
IUUC-Pgr-103611	Puccinia graminis	71.53	7.00e-52	195.00
IUUC-Ptt-103971	Puccinia triticina	72.88	2.00e-44	170.00
IUUC-Pte-104378	Pyrenophora teres	67.15	7.00e-57	211.00
IUUC-Pyt-104757	Pyrenophora triticirepentis	67.15	7.00e-57	211.00
IUUC-Rno-105772	Rattus norvegicus	98.57	1.00e-79	288.00
IUUC-Sce-106283	Saccharomyces cerevisiae	65.69	4.00e-54	203.00
IUUC-Sha-107650	Sarcophilus harrisii	97.14	2.00e-77	280.00
IUUC-Sja-107790	Schizosaccharomyces japonicus	68.61	1.00e-50	191.00
IUUC-Spo-108073	Schizosaccharomyces pombe	68.61	7.00e-51	192.00
IUUC-Ssl-108432	Sclerotinia sclerotiorum	65.71	8.00e-57	211.00
IUUC-Smo-109036	Selaginella moellendorffii	74.45	4.00e-62	229.00
IUUC-Sit-110731	Setaria italica	73.72	1.00e-61	228.00
IUUC-Sly-111506	Solanum lycopersicum	74.45	4.00e-62	229.00
IUUC-Stu-112080	Solanum tuberosum	74.45	4.00e-62	229.00
IUUC-Sar-113429	Sorex araneus	98.57	3.00e-79	286.00
IUUC-Sbi-114289	Sorghum bicolor	73.72	1.00e-61	228.00
IUUC-Sre-115106	Sporisorium reilianum	73.38	5.00e-53	199.00
IUUC-Ssc-115257	Sus scrofa	96.43	3.00e-77	279.00
IUUC-Tgu-116604	Taeniopygia guttata	92.00	6.00e-77	278.00
IUUC-Tru-118576	Takifugu rubripes	92.86	6.00e-75	272.00
IUUC-Tsy-119000	Tarsius syrichta	98.57	3.00e-79	286.00
IUUC-Tni-119745	Tetraodon nigroviridis	92.86	3.00e-75	273.00
IUUC-Tca-121827	Theobroma cacao	73.72	6.00e-62	228.00
IUUC-Tre-122002	Trichoderma reesei	65.47	3.00e-56	209.00
IUUC-Tvi-122331	Trichoderma virens	65.47	3.00e-56	209.00
IUUC-Tae-124461	Triticum aestivum	72.26	4.00e-61	227.00
IUUC-Tur-126866	Triticum urartu	72.99	2.00e-61	226.00
IUUC-Tme-127148	Tuber melanosporum	68.89	1.00e-56	211.00
IUUC-Tbe-127921	Tupaia belangeri	96.43	8.00e-75	271.00
IUUC-Ttr-129121	Tursiops truncatus	98.57	3.00e-79	286.00
IUUC-Uma-129561	Ustilago maydis	74.45	3.00e-53	200.00
IUUC-Vda-129711	Verticillium dahliae	65.47	1.00e-56	211.00
IUUC-Vpa-130570	Vicugna pacos	93.43	3.00e-71	259.00
IUUC-Vvi-131108	Vitis vinifera	75.18	2.00e-62	230.00
IUUC-Xtr-131824	Xenopus tropicalis	97.14	5.00e-78	282.00
IUUC-Xma-133667	Xiphophorus maculatus	93.57	2.00e-76	276.00
IUUC-Yli-134660	Yarrowia lipolytica	62.59	3.00e-55	206.00
IUUC-Zma-135584	Zea mays	72.26	1.00e-60	225.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence