iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033996

Ensembl Protein ID

ENSECAP00000018587.1

UniProt Accession

F6VNA3; F6VNA3_HORSE

Protein Name

Uncharacterized protein

Gene Name

TBK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000020820.1	ENSECAT00000022485.1	ENSECAP00000018587.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	3.00e-06	27.2	311	386

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL..eddktLady.glkdgstihllekks 74
           ++v sl+ +  +++ +++++t a++ e ++k+++i +  q Liy+G+ L  e+++  +++ + ++++ i+++ +++
   Q: 311  IHVFSLQQMtAHKIYIHSYNTAAVFHELVYKQTKIISSNQELIYEGRRLvlEPGRLAQHLpKTTEDNPIFVVSQEP 386
           7899999999**************************************999*****9999***********98876 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MQSTSNHLWL LSDILGQGAT ANVFRGRHKK TGDLFAIKVF NNISFLRPVD VQMREFEVLK 60
KLNHKNIVKL FAIEEETTTR HKVLVMEFCP CGSLYTVLEE PSNAYGLPES EFLIVLRDVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGTGTAACA AGAGGACCGC CTGCCCAAGC CGAGATGCAG AGCACTTCTA ATCACCTCTG 60
GCTCTTGTCG GATATTTTAG GCCAAGGAGC TACTGCAAAT GTCTTTCGAG GAAGACATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0002218--P:activation of innate immune response
GO:0050830--P:defense response to Gram-positive bacterium
GO:0044565--P:dendritic cell proliferation
GO:0045087--P:innate immune response
GO:0010629--P:negative regulation of gene expression
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032727--P:positive regulation of interferon-alpha production
GO:0045359--P:positive regulation of interferon-beta biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:1904417--P:positive regulation of xenophagy

KEGG

ecb:100051650

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001638	Ailuropoda melanoleuca	96.02	0.00e+00	1478.00
IUUC-Apl-004028	Anas platyrhynchos	87.38	0.00e+00	1358.00
IUUC-Aca-004998	Anolis carolinensis	82.85	0.00e+00	1289.00
IUUC-Ame-011617	Astyanax mexicanus	70.34	0.00e+00	1061.00
IUUC-Bta-012799	Bos taurus	95.61	0.00e+00	1475.00
IUUC-Cja-019357	Callithrix jacchus	95.07	0.00e+00	1464.00
IUUC-Cfa-020309	Canis familiaris	96.02	0.00e+00	1476.00
IUUC-Cpo-022062	Cavia porcellus	94.38	0.00e+00	1452.00
IUUC-Csa-023517	Chlorocebus sabaeus	95.06	0.00e+00	1469.00
IUUC-Cho-025037	Choloepus hoffmanni	91.31	0.00e+00	956.00
IUUC-Cin-025580	Ciona intestinalis	40.43	4.00e-149	521.00
IUUC-Csv-025818	Ciona savignyi	40.89	2.00e-143	503.00
IUUC-Dre-027527	Danio rerio	70.33	0.00e+00	1070.00
IUUC-Dno-029475	Dasypus novemcinctus	83.99	0.00e+00	1120.00
IUUC-Dme-031698	Drosophila melanogaster	39.26	9.00e-133	467.00
IUUC-Ete-033090	Echinops telfairi	81.76	0.00e+00	1219.00
IUUC-Eeu-035082	Erinaceus europaeus	86.82	0.00e+00	853.00
IUUC-Fca-035921	Felis catus	92.21	0.00e+00	1412.00
IUUC-Fal-037406	Ficedula albicollis	87.24	0.00e+00	1359.00
IUUC-Gmo-038721	Gadus morhua	70.99	0.00e+00	1050.00
IUUC-Gga-041234	Gallus gallus	86.56	0.00e+00	1351.00
IUUC-Gac-042315	Gasterosteus aculeatus	71.72	0.00e+00	1072.00
IUUC-Ggo-044885	Gorilla gorilla	88.61	0.00e+00	1349.00
IUUC-Hsa-046847	Homo sapiens	94.92	0.00e+00	1467.00
IUUC-Itr-047906	Ictidomys tridecemlineatus	94.69	0.00e+00	1457.00
IUUC-Lch-049731	Latimeria chalumnae	54.76	0.00e+00	781.00
IUUC-Loc-051879	Lepisosteus oculatus	72.80	0.00e+00	1106.00
IUUC-Laf-054232	Loxodonta africana	93.70	0.00e+00	1447.00
IUUC-Mcc-055447	Macaca mulatta	95.20	0.00e+00	1471.00
IUUC-Meu-056138	Macropus eugenii	97.28	0.00e+00	684.00
IUUC-Mga-059460	Meleagris gallopavo	85.09	0.00e+00	1320.00
IUUC-Mmr-061445	Microcebus murinus	95.20	0.00e+00	1465.00
IUUC-Mmu-064107	Mus musculus	92.46	0.00e+00	1413.00
IUUC-Mpu-066834	Mustela putorius furo	96.16	0.00e+00	1480.00
IUUC-Mlu-068006	Myotis lucifugus	92.19	0.00e+00	1397.00
IUUC-Nle-069280	Nomascus leucogenys	94.92	0.00e+00	1469.00
IUUC-Opr-070728	Ochotona princeps	86.52	0.00e+00	1174.00
IUUC-Ont-071621	Oreochromis niloticus	72.60	0.00e+00	1083.00
IUUC-Oan-073162	Ornithorhynchus anatinus	91.00	0.00e+00	1360.00
IUUC-Ocu-074787	Oryctolagus cuniculus	95.48	0.00e+00	1468.00
IUUC-Ola-086737	Oryzias latipes	33.48	2.00e-28	120.00
IUUC-Oga-088764	Otolemur garnettii	94.10	0.00e+00	1452.00
IUUC-Oar-090333	Ovis aries	95.34	0.00e+00	1469.00
IUUC-Ptr-090568	Pan troglodytes	94.51	0.00e+00	1462.00
IUUC-Pan-091979	Papio anubis	94.94	0.00e+00	1462.00
IUUC-Psi-093336	Pelodiscus sinensis	86.56	0.00e+00	1334.00
IUUC-Pma-094200	Petromyzon marinus	43.98	2.00e-176	612.00
IUUC-Pfo-096354	Poecilia formosa	71.96	0.00e+00	1080.00
IUUC-Pab-098499	Pongo abelii	95.06	0.00e+00	1468.00
IUUC-Pva-102454	Pteropus vampyrus	94.24	0.00e+00	1434.00
IUUC-Rno-105595	Rattus norvegicus	92.04	0.00e+00	1402.00
IUUC-Sha-106864	Sarcophilus harrisii	92.49	0.00e+00	1432.00
IUUC-Sar-113728	Sorex araneus	87.29	0.00e+00	1257.00
IUUC-Tgu-117200	Taeniopygia guttata	86.34	0.00e+00	1342.00
IUUC-Tsy-119017	Tarsius syrichta	93.75	0.00e+00	1075.00
IUUC-Tni-120724	Tetraodon nigroviridis	70.94	0.00e+00	1070.00
IUUC-Tbe-127887	Tupaia belangeri	85.84	0.00e+00	1027.00
IUUC-Ttr-129111	Tursiops truncatus	88.20	0.00e+00	1337.00
IUUC-Vpa-130724	Vicugna pacos	96.30	0.00e+00	1480.00
IUUC-Xtr-132091	Xenopus tropicalis	74.28	0.00e+00	1160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence