iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106864

Ensembl Protein ID

ENSSHAP00000007277.1

UniProt Accession

G3VVS2; G3VVS2_SARHA

Genbank Protein ID

ENSSHAP00000007277

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01205942

Gene Name

TBK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000006325.1	ENSSHAT00000007339.1	ENSSHAP00000007277.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	91.53	0.00e+00	1425.00	IUUC-Mmu-064107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MQSTSNHLWL LSDILGQGAT ANVFRGRHKK TGDLFAVKVF NSISFLRPVD VQMREFEVLK 60
KLNHKNIVKL FAIEEETTTR HKVLVMEFCP CGSLYTVLEE PSNAYGLPES EFLIVLRDVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGAGTA CTTCTAATCA TCTGTGGCTC CTATCTGATA TCCTAGGGCA AGGAGCCACT 60
GCAAATGTTT TTCGTGGAAG ACATAAGGTT AGTGTGGGGA AAATTGTAGA ATTTGAGAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0002218--P:activation of innate immune response
GO:0050830--P:defense response to Gram-positive bacterium
GO:0044565--P:dendritic cell proliferation
GO:0010629--P:negative regulation of gene expression
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032727--P:positive regulation of interferon-alpha production
GO:0045359--P:positive regulation of interferon-beta biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:1904417--P:positive regulation of xenophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001638	Ailuropoda melanoleuca	93.58	0.00e+00	1450.00
IUUC-Apl-004028	Anas platyrhynchos	87.16	0.00e+00	1353.00
IUUC-Aca-004998	Anolis carolinensis	83.20	0.00e+00	1291.00
IUUC-Ame-011617	Astyanax mexicanus	71.15	0.00e+00	1060.00
IUUC-Bta-012799	Bos taurus	93.44	0.00e+00	1447.00
IUUC-Cja-019357	Callithrix jacchus	93.58	0.00e+00	1450.00
IUUC-Cfa-020309	Canis familiaris	93.44	0.00e+00	1447.00
IUUC-Cpo-022062	Cavia porcellus	92.62	0.00e+00	1433.00
IUUC-Csa-023517	Chlorocebus sabaeus	93.44	0.00e+00	1448.00
IUUC-Cho-025037	Choloepus hoffmanni	91.11	0.00e+00	957.00
IUUC-Cin-025580	Ciona intestinalis	39.91	1.00e-148	520.00
IUUC-Csv-025818	Ciona savignyi	39.66	2.00e-142	499.00
IUUC-Dre-027527	Danio rerio	70.41	0.00e+00	1067.00
IUUC-Dno-029475	Dasypus novemcinctus	81.46	0.00e+00	1106.00
IUUC-Dme-031698	Drosophila melanogaster	40.53	9.00e-129	454.00
IUUC-Ete-033090	Echinops telfairi	79.92	0.00e+00	1196.00
IUUC-Eca-033996	Equus caballus	92.49	0.00e+00	1432.00
IUUC-Eeu-035082	Erinaceus europaeus	84.20	0.00e+00	836.00
IUUC-Fca-035921	Felis catus	89.93	0.00e+00	1385.00
IUUC-Fal-037406	Ficedula albicollis	87.30	0.00e+00	1359.00
IUUC-Gmo-038721	Gadus morhua	70.85	0.00e+00	1044.00
IUUC-Gga-041234	Gallus gallus	86.89	0.00e+00	1353.00
IUUC-Gac-042315	Gasterosteus aculeatus	71.15	0.00e+00	1060.00
IUUC-Ggo-044885	Gorilla gorilla	87.16	0.00e+00	1335.00
IUUC-Hsa-046847	Homo sapiens	93.17	0.00e+00	1446.00
IUUC-Itr-047906	Ictidomys tridecemlineatus	92.38	0.00e+00	1431.00
IUUC-Lch-049731	Latimeria chalumnae	53.84	0.00e+00	763.00
IUUC-Loc-051879	Lepisosteus oculatus	72.78	0.00e+00	1104.00
IUUC-Laf-054232	Loxodonta africana	92.21	0.00e+00	1432.00
IUUC-Mcc-055447	Macaca mulatta	93.58	0.00e+00	1449.00
IUUC-Meu-056138	Macropus eugenii	98.50	0.00e+00	692.00
IUUC-Mga-059460	Meleagris gallopavo	85.79	0.00e+00	1330.00
IUUC-Mmr-061445	Microcebus murinus	93.17	0.00e+00	1443.00
IUUC-Mmu-064107	Mus musculus	91.53	0.00e+00	1398.00
IUUC-Mpu-066834	Mustela putorius furo	93.72	0.00e+00	1451.00
IUUC-Mlu-068006	Myotis lucifugus	90.16	0.00e+00	1377.00
IUUC-Nle-069280	Nomascus leucogenys	93.03	0.00e+00	1445.00
IUUC-Opr-070728	Ochotona princeps	84.60	0.00e+00	1155.00
IUUC-Ont-071621	Oreochromis niloticus	72.17	0.00e+00	1079.00
IUUC-Oan-073162	Ornithorhynchus anatinus	91.75	0.00e+00	1366.00
IUUC-Ocu-074787	Oryctolagus cuniculus	93.85	0.00e+00	1455.00
IUUC-Ola-086737	Oryzias latipes	32.16	5.00e-26	112.00
IUUC-Oga-088764	Otolemur garnettii	91.94	0.00e+00	1428.00
IUUC-Oar-090333	Ovis aries	93.44	0.00e+00	1447.00
IUUC-Ptr-090568	Pan troglodytes	92.90	0.00e+00	1443.00
IUUC-Pan-091979	Papio anubis	93.59	0.00e+00	1448.00
IUUC-Psi-093336	Pelodiscus sinensis	87.30	0.00e+00	1343.00
IUUC-Pma-094200	Petromyzon marinus	43.39	9.00e-174	603.00
IUUC-Pfo-096354	Poecilia formosa	71.80	0.00e+00	1074.00
IUUC-Pab-098499	Pongo abelii	93.31	0.00e+00	1446.00
IUUC-Pva-102454	Pteropus vampyrus	91.67	0.00e+00	1399.00
IUUC-Rno-105595	Rattus norvegicus	91.12	0.00e+00	1389.00
IUUC-Sar-113728	Sorex araneus	84.64	0.00e+00	1228.00
IUUC-Tgu-117200	Taeniopygia guttata	85.99	0.00e+00	1337.00
IUUC-Tsy-119017	Tarsius syrichta	92.50	0.00e+00	1064.00
IUUC-Tni-120724	Tetraodon nigroviridis	70.64	0.00e+00	1063.00
IUUC-Tbe-127887	Tupaia belangeri	84.04	0.00e+00	1016.00
IUUC-Ttr-129111	Tursiops truncatus	85.93	0.00e+00	1307.00
IUUC-Vpa-130724	Vicugna pacos	93.85	0.00e+00	1452.00
IUUC-Xtr-132091	Xenopus tropicalis	74.80	0.00e+00	1161.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence