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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Hsa-046329
Ensembl Protein ID ENSP00000383981.3
UniProt Accession P62979; P02248; P02249; P02250; P14798; P62988; Q29120; Q6LBL4; Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8; Q9UPK7; RS27A_HUMAN
Genbank Protein ID CAA44911.1; AAB21188.1; AAH01392.1; AAH66293.1; BAB79490.1; AAA36788.1; BAA25826.1
Protein Name Ubiquitin-40S ribosomal protein S27a; Ubiquitin carboxyl extension protein 80; Ubiquitin; 40S ribosomal protein S27a; Small ribosomal subunit protein eS31
Genbank Nucleotide ID X63237; S79522; AC012358; BC066293; AB062071; M10939; AB007163
Gene Name RPS27A; UBA80; UBCEP1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000143947.12 ENST00000402285.7 ENSP00000383981.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACmiRWalk
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Protein 3D Structure
PDBMMDB
Disease-associated Information
OMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDUniProtBioGRID
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
ULD/UDP/UBQ/UBQ_PIM UBQ_PIM 10772958; 12826399
Classification
Family E-value Score Start End
ULD/UBL/NEDD8 9.90e-41 139.5 1 76
ULD/UDP/UBQ/UBQ_PIM 4.30e-29 101.9 1 73
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UBL/NEDD8

   S: 1    mlikvktLtgkeieieieesdtierikerveekeGiPPsqqrliyaGkqleddktaadynlekgsvLhLvLaLrGG 76
    m+i+vktLtgk+i++e+e+sdtie++k+++++keGiPP+qqrli+aGkqled++t++dyn++k+s+LhLvL+LrGG
   Q: 1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76
    89*************************************************************************9 PP
   


   ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkk 73
    m+++vktl+gk+++lev+++dt+e++K+ki+++ g+pp+qq+LI+aGk+L+D +tLs+++i+++s++hlv++
   Q: 1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRL 73
    99********************************************************************986 PP
   

Organism Homo sapiens
Functional Description
(View)

Functional Description



     Ribosomal protein S27a is part of the 40S ribosomal subunit.
Ribosomal protein S27a is part of the 40S ribosomal subunit.
Protein Sequence
(Fasta)
MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN 60
IQKESTLHLV LRLRGGAKKR KKKSYTTPKK NKHKRKKVKL AVLKYYKVDE NGKISRLRRE 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Hsa-046329|ULD,NEDD8;ULD,UBQ_PIM|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAGACCCAGA CTCTTCCCTA GGCTGGGAGA GACTCGGCGG TTGAAAGCAG GGAGGCGCTA 60
CAGGAGAGAA AGGGCTGAAC CCCCGCTTCC GCAGATTTCA CCTATTTTTC AGTTTGCCTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Hsa-046329|ULD,NEDD8;ULD,UBQ_PIM|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0687--Ribonucleoprotein
KW-0689--Ribosomal protein
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002906--Ribosomal_S27a
IPR011332--Ribosomal_zn-bd
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2

Pfam

PF01599--Ribosomal_S27
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM01402--Ribosomal_S27
SM00213--UBQ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0022627--C:cytosolic small ribosomal subunit
GO:0030666--C:endocytic vesicle membrane
GO:0044322--C:endoplasmic reticulum quality control compartment
GO:0010008--C:endosome membrane
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0016020--C:membrane
GO:0005741--C:mitochondrial outer membrane
GO:0043209--C:myelin sheath
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0015935--C:small ribosomal subunit
GO:0046872--F:metal ion binding
GO:0003723--F:RNA binding
GO:0003735--F:structural constituent of ribosome
GO:0000187--P:activation of MAPK activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0044267--P:cellular protein metabolic process
GO:0042769--P:DNA damage response, detection of DNA damage
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:1904380--P:endoplasmic reticulum mannose trimming
GO:0016197--P:endosomal transport
GO:0035635--P:entry of bacterium into host cell
GO:0038128--P:ERBB2 signaling pathway
GO:0070987--P:error-free translesion synthesis
GO:0042276--P:error-prone translesion synthesis
GO:0038095--P:Fc-epsilon receptor signaling pathway
GO:0008543--P:fibroblast growth factor receptor signaling pathway
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0070911--P:global genome nucleotide-excision repair
GO:0005978--P:glycogen biosynthetic process
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0045087--P:innate immune response
GO:0036297--P:interstrand cross-link repair
GO:0075733--P:intracellular transport of virus
GO:0034220--P:ion transmembrane transport
GO:0007254--P:JNK cascade
GO:0016236--P:macroautophagy
GO:0000165--P:MAPK cascade
GO:0061024--P:membrane organization
GO:0002755--P:MyD88-dependent toll-like receptor signaling pathway
GO:0002756--P:MyD88-independent toll-like receptor signaling pathway
GO:0043066--P:negative regulation of apoptotic process
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0010972--P:negative regulation of G2/M transition of mitotic cell cycle
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0051436--P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0038061--P:NIK/NF-kappaB signaling
GO:0007219--P:Notch signaling pathway
GO:0000184--P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0070423--P:nucleotide-binding oligomerization domain containing signaling pathway
GO:0000715--P:nucleotide-excision repair, DNA damage recognition
GO:0000717--P:nucleotide-excision repair, DNA duplex unwinding
GO:0006297--P:nucleotide-excision repair, DNA gap filling
GO:0033683--P:nucleotide-excision repair, DNA incision
GO:0006296--P:nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006294--P:nucleotide-excision repair, preincision complex assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0045742--P:positive regulation of epidermal growth factor receptor signaling pathway
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0051437--P:positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0006457--P:protein folding
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043488--P:regulation of mRNA stability
GO:0060544--P:regulation of necroptotic process
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0061418--P:regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0010803--P:regulation of tumor necrosis factor-mediated signaling pathway
GO:0032479--P:regulation of type I interferon production
GO:0006364--P:rRNA processing
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0006614--P:SRP-dependent cotranslational protein targeting to membrane
GO:0002223--P:stimulatory C-type lectin receptor signaling pathway
GO:0051403--P:stress-activated MAPK cascade
GO:0050852--P:T cell receptor signaling pathway
GO:0006283--P:transcription-coupled nucleotide-excision repair
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:0006412--P:translation
GO:0006413--P:translational initiation
GO:0019985--P:translesion synthesis
GO:0055085--P:transmembrane transport
GO:0035666--P:TRIF-dependent toll-like receptor signaling pathway
GO:0033209--P:tumor necrosis factor-mediated signaling pathway
GO:0019058--P:viral life cycle
GO:0019083--P:viral transcription
GO:0019068--P:virion assembly
GO:0016055--P:Wnt signaling pathway
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

KEGG hsa:6233
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001873 Ailuropoda melanoleuca 100.00 2.00e-68 250.00
IUUC-Atr-003143 Amborella trichopoda 84.21 1.00e-61 228.00
IUUC-Apl-003364 Anas platyrhynchos 89.74 5.00e-60 223.00
IUUC-Aca-005055 Anolis carolinensis 98.72 3.00e-74 270.00
IUUC-Aly-005675 Arabidopsis lyrata 85.53 4.00e-62 230.00
IUUC-Ath-006984 Arabidopsis thaliana 85.53 4.00e-62 230.00
IUUC-Ago-007733 Ashbya gossypii 81.76 2.00e-53 201.00
IUUC-Acl-008099 Aspergillus clavatus 86.18 2.00e-55 208.00
IUUC-Afl-008474 Aspergillus flavus 86.18 3.00e-55 207.00
IUUC-Afu-009021 Aspergillus fumigatus 86.84 6.00e-61 226.00
IUUC-Ani-009265 Aspergillus nidulans 86.18 5.00e-55 206.00
IUUC-Ang-009629 Aspergillus niger 85.53 2.00e-55 207.00
IUUC-Aor-009936 Aspergillus oryzae 86.18 3.00e-55 207.00
IUUC-Ate-010436 Aspergillus terreus 86.18 2.00e-55 207.00
IUUC-Ame-011421 Astyanax mexicanus 98.72 2.00e-67 248.00
IUUC-Bgr-011984 Blumeria graminis 86.75 2.00e-60 224.00
IUUC-Bta-012585 Bos taurus 100.00 2.00e-68 250.00
IUUC-Bci-013920 Botrytis cinerea 86.75 3.00e-55 207.00
IUUC-Bdi-014571 Brachypodium distachyon 84.97 6.00e-56 209.00
IUUC-Bol-016477 Brassica oleracea 83.97 2.00e-62 231.00
IUUC-Cja-019661 Callithrix jacchus 99.36 4.00e-67 246.00
IUUC-Cfa-020795 Canis familiaris 100.00 2.00e-68 250.00
IUUC-Cpo-021905 Cavia porcellus 98.73 5.00e-67 246.00
IUUC-Csa-023120 Chlorocebus sabaeus 100.00 2.00e-68 250.00
IUUC-Cin-025785 Ciona intestinalis 89.74 8.00e-60 222.00
IUUC-Csv-026028 Ciona savignyi 81.17 2.00e-52 197.00
IUUC-Cgl-026423 Colletotrichum gloeosporioides 79.22 1.00e-49 188.00
IUUC-Cme-027207 Cyanidioschyzon merolae 98.68 8.00e-40 155.00
IUUC-Dre-028206 Danio rerio 98.72 2.00e-67 248.00
IUUC-Dno-029073 Dasypus novemcinctus 100.00 2.00e-68 251.00
IUUC-Dor-030658 Dipodomys ordii 100.00 6.00e-41 158.00
IUUC-Dse-031483 Dothistroma septosporum 83.87 2.00e-59 221.00
IUUC-Dme-032068 Drosophila melanogaster 91.03 2.00e-59 221.00
IUUC-Ete-032297 Echinops telfairi 70.51 5.00e-58 216.00
IUUC-Eca-034346 Equus caballus 100.00 1.00e-68 251.00
IUUC-Eeu-035081 Erinaceus europaeus 89.72 5.00e-37 145.00
IUUC-Fca-035555 Felis catus 100.00 2.00e-68 250.00
IUUC-Fal-037049 Ficedula albicollis 99.36 7.00e-68 249.00
IUUC-Fox-037994 Fusarium oxysporum 87.58 6.00e-61 226.00
IUUC-Fso-038121 Fusarium solani 88.16 3.00e-62 230.00
IUUC-Gmo-039231 Gadus morhua 98.72 2.00e-67 247.00
IUUC-Ggr-039996 Gaeumannomyces graminis 84.42 2.00e-55 207.00
IUUC-Gga-040938 Gallus gallus 99.36 7.00e-68 249.00
IUUC-Gac-041956 Gasterosteus aculeatus 98.72 1.00e-67 248.00
IUUC-Gma-043007 Glycine max 84.42 6.00e-63 233.00
IUUC-Ggo-044980 Gorilla gorilla 100.00 2.00e-68 250.00
IUUC-Itr-047994 Ictidomys tridecemlineatus 100.00 2.00e-68 250.00
IUUC-Kpa-049159 Komagataella pastoris 82.24 3.00e-56 210.00
IUUC-Lch-050032 Latimeria chalumnae 98.08 7.00e-67 245.00
IUUC-Loc-052020 Lepisosteus oculatus 98.72 2.00e-67 247.00
IUUC-Lma-053163 Leptosphaeria maculans 85.06 2.00e-60 224.00
IUUC-Laf-054502 Loxodonta africana 97.22 9.00e-58 215.00
IUUC-Mcc-055895 Macaca mulatta 100.00 2.00e-68 250.00
IUUC-Meu-056529 Macropus eugenii 100.00 2.00e-68 250.00
IUUC-Mor-056959 Magnaporthe oryzae 84.42 2.00e-55 207.00
IUUC-Mpo-057436 Magnaporthe poae 84.42 2.00e-55 207.00
IUUC-Mtr-058743 Medicago truncatula 84.42 2.00e-63 234.00
IUUC-Mla-058871 Melampsora laricipopulina 86.09 7.00e-61 226.00
IUUC-Mga-059211 Meleagris gallopavo 95.21 1.00e-58 218.00
IUUC-Mvi-060484 Microbotryum violaceum 82.58 7.00e-59 219.00
IUUC-Mmr-060710 Microcebus murinus 99.36 9.00e-75 271.00
IUUC-Mdo-062150 Monodelphis domestica 98.73 2.00e-67 247.00
IUUC-Mmu-064336 Mus musculus 99.36 9.00e-68 248.00
IUUC-Mac-064616 Musa acuminata 83.87 9.00e-62 228.00
IUUC-Mpu-066613 Mustela putorius furo 100.00 2.00e-68 250.00
IUUC-Mlu-067676 Myotis lucifugus 100.00 2.00e-68 250.00
IUUC-Nfi-068350 Neosartorya fischeri 86.84 6.00e-61 226.00
IUUC-Ncr-068635 Neurospora crassa 86.18 2.00e-55 207.00
IUUC-Nle-069607 Nomascus leucogenys 96.79 1.00e-65 241.00
IUUC-Opr-070523 Ochotona princeps 98.71 2.00e-65 240.00
IUUC-Ont-071636 Oreochromis niloticus 98.72 2.00e-67 248.00
IUUC-Oan-073638 Ornithorhynchus anatinus 100.00 3.00e-68 251.00
IUUC-Ocu-074497 Oryctolagus cuniculus 100.00 2.00e-68 250.00
IUUC-Oba-075488 Oryza barthii 84.97 5.00e-56 209.00
IUUC-Obr-076443 Oryza brachyantha 84.97 5.00e-56 209.00
IUUC-Ogl-077000 Oryza glaberrima 84.97 5.00e-56 209.00
IUUC-Oin-080161 Oryza indica 84.97 5.00e-56 209.00
IUUC-Olo-080936 Oryza longistaminata 70.37 1.00e-19 87.80
IUUC-Ome-081322 Oryza meridionalis 84.97 5.00e-56 209.00
IUUC-Oru-085032 Oryza rufipogon 84.97 5.00e-56 209.00
IUUC-Osa-085398 Oryza sativa 84.97 5.00e-56 209.00
IUUC-Ola-086383 Oryzias latipes 98.08 1.00e-66 244.00
IUUC-Olu-087619 Ostreococcus lucimarinus 81.33 2.00e-46 177.00
IUUC-Oga-089160 Otolemur garnettii 94.87 8.00e-69 252.00
IUUC-Oar-090107 Ovis aries 100.00 2.00e-68 251.00
IUUC-Ptr-090693 Pan troglodytes 100.00 2.00e-68 250.00
IUUC-Pan-092065 Papio anubis 100.00 2.00e-68 250.00
IUUC-Psi-093901 Pelodiscus sinensis 99.29 1.00e-58 218.00
IUUC-Pma-094647 Petromyzon marinus 93.44 8.00e-43 165.00
IUUC-Ppa-095330 Physcomitrella patens 84.87 6.00e-62 229.00
IUUC-Pfo-097442 Poecilia formosa 98.72 2.00e-67 248.00
IUUC-Pab-098246 Pongo abelii 94.87 1.00e-65 241.00
IUUC-Pop-099335 Populus trichocarpa 84.97 1.00e-62 231.00
IUUC-Ppe-101784 Prunus persica 84.97 1.00e-62 231.00
IUUC-Pva-102665 Pteropus vampyrus 98.01 1.00e-62 231.00
IUUC-Pgr-103596 Puccinia graminis 84.77 4.00e-56 210.00
IUUC-Ptt-103852 Puccinia triticina 67.30 7.00e-47 181.00
IUUC-Pte-104221 Pyrenophora teres 85.71 1.00e-60 225.00
IUUC-Pyt-104464 Pyrenophora triticirepentis 84.42 2.00e-59 221.00
IUUC-Rno-105805 Rattus norvegicus 99.36 9.00e-68 248.00
IUUC-Sce-106232 Saccharomyces cerevisiae 82.78 8.00e-54 202.00
IUUC-Sha-106772 Sarcophilus harrisii 100.00 2.00e-68 251.00
IUUC-Sja-107885 Schizosaccharomyces japonicus 86.39 8.00e-57 212.00
IUUC-Spo-108212 Schizosaccharomyces pombe 83.67 1.00e-48 185.00
IUUC-Ssl-108492 Sclerotinia sclerotiorum 86.75 3.00e-55 207.00
IUUC-Sit-110054 Setaria italica 84.97 7.00e-62 229.00
IUUC-Sly-111074 Solanum lycopersicum 84.97 6.00e-62 229.00
IUUC-Stu-112439 Solanum tuberosum 85.62 3.00e-63 233.00
IUUC-Sbi-113920 Sorghum bicolor 85.62 2.00e-62 231.00
IUUC-Sre-114920 Sporisorium reilianum 84.67 1.00e-56 211.00
IUUC-Ssc-115514 Sus scrofa 100.00 2.00e-68 250.00
IUUC-Tgu-116890 Taeniopygia guttata 98.73 1.00e-66 244.00
IUUC-Tru-118475 Takifugu rubripes 98.72 2.00e-67 247.00
IUUC-Tsy-119447 Tarsius syrichta 99.36 7.00e-68 249.00
IUUC-Tni-119751 Tetraodon nigroviridis 97.14 6.00e-57 212.00
IUUC-Tca-121126 Theobroma cacao 84.97 1.00e-62 231.00
IUUC-Tre-122027 Trichoderma reesei 86.84 8.00e-61 225.00
IUUC-Tvi-122659 Trichoderma virens 86.84 8.00e-61 225.00
IUUC-Tae-124683 Triticum aestivum 84.97 6.00e-56 209.00
IUUC-Tme-126994 Tuber melanosporum 86.09 2.00e-54 204.00
IUUC-Tbe-127851 Tupaia belangeri 100.00 6.00e-41 158.00
IUUC-Ttr-128453 Tursiops truncatus 100.00 2.00e-68 250.00
IUUC-Uma-129571 Ustilago maydis 84.00 3.00e-56 210.00
IUUC-Vda-129762 Verticillium dahliae 86.18 1.00e-55 208.00
IUUC-Vpa-130119 Vicugna pacos 81.41 5.00e-47 179.00
IUUC-Vvi-131376 Vitis vinifera 84.97 4.00e-63 233.00
IUUC-Xtr-131977 Xenopus tropicalis 91.67 7.00e-60 222.00
IUUC-Xma-133747 Xiphophorus maculatus 98.36 2.00e-47 181.00
IUUC-Yli-134406 Yarrowia lipolytica 85.03 2.00e-47 181.00
Created Date 25-Jun-2017

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