iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073598

Ensembl Protein ID

ENSOANP00000019888.1

UniProt Accession

F7D8W7; F7D8W7_ORNAN

Protein Name

Uncharacterized protein

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000012576.2	ENSOANT00000019891.2	ENSOANP00000019888.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-27	93.6	1728	1760
UBD/Beta-Prp	1.50e-54	185.5	1353	1635

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           Ht++vtc++f +d  +l+sGs+D ++ +W++++
   Q: 1728 HTGPVTCCSFsPDgQYLASGSRDWSLLCWRVDS 1760
           ***********999***************9876 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc.vhtlkgheds 96
           s+ t++ +sp+++  a+gs+dg +++ d+++++  rsl +  ++++++ f +d+ ++  ++ D+++ +wdl+ + c ++  ++h++ 
   Q: 1353 SPATALGISPNGRCAAVGSADGVLRLLDLRSWQEERSLVSGCDGISSCVFLSDS-TIYIAAFDGILELWDLQGSGCrIQRTQAHQFH 1438
           67899999******************************8888899999999998.6777889**********6666156667***** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           ++ + +s +++ l++ s d  +++wd+  g     ++    g  +cv++hp+++l++ G+ ++   + +l   ++   l g+  +sv
   Q: 1439 ITGCGLSLDRKLLATVSLDGALKLWDTMGGRPG--LQHTAPGPLSCVTFHPKEQLVAIGGWNGSTTVLRLDDLTVSSVL-GASGPSV 1522
           *****************************9999..5999999**************************99777777777.569**** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisv 270
           + ++f ++g  lv g ldg v+lw  ++g  + t+ +h+  ++   f+  +  l+++++Dg +++W    g++ ++l  ++ s    
   Q: 1523 RAVTFAPSGLGLVVGRLDGAVELWAWREGVQLATFPAHRGGTTAALFLHAGRCLLTTGEDGKVQVWSGSLGQPRGSLGSPHLSPALA 1609
           *********************************************************************************888888 PP
   S: 271  avlsfgdnvlvlgsedskvniwklkk 296
            +ls+++  ++ g   + +++++++ 
   Q: 1610 VALSPDGARVAVGHRADGIRVYAVSG 1635
           889***999999999889***99865 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

QGLAGDPQGK LVPLPACLRA AMADKFVQFD QYQLRKYLPR THRAKSCRRA PPRLPAQKSK 60
PPSTQAWKKL TFLVQKFGEE QSKFEAAADS PGVRKNAPRE QFTLKKLVQR LHLRDPAEHV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGCTGCTG TCTGCCCAAG ATCTGGCAAC CGTTCCCCTC TCCCTGCAGG GTTTGGCAGG 60
CGACCCTCAG GGCAAGCTGG TCCCGCTGCC CGCCTGTCTC CGAGCTGCGA TGGCCGACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR023302--Pept_S9A_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0071011--C:precatalytic spliceosome
GO:0005697--C:telomerase holoenzyme complex
GO:0005682--C:U5 snRNP
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0008380--P:RNA splicing
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	52.54	0.00e+00	2025.00
IUUC-Aca-005102	Anolis carolinensis	39.76	0.00e+00	1385.00
IUUC-Ame-011822	Astyanax mexicanus	34.81	1.00e-156	548.00
IUUC-Bta-012323	Bos taurus	52.20	0.00e+00	2036.00
IUUC-Cja-019005	Callithrix jacchus	52.35	0.00e+00	2130.00
IUUC-Cfa-020803	Canis familiaris	51.97	0.00e+00	1889.00
IUUC-Cpo-022312	Cavia porcellus	52.22	0.00e+00	2039.00
IUUC-Csa-023287	Chlorocebus sabaeus	52.96	0.00e+00	2094.00
IUUC-Dre-028825	Danio rerio	32.80	0.00e+00	918.00
IUUC-Dno-029455	Dasypus novemcinctus	51.32	0.00e+00	1976.00
IUUC-Dor-030328	Dipodomys ordii	48.16	0.00e+00	1489.00
IUUC-Ete-032385	Echinops telfairi	53.86	0.00e+00	1066.00
IUUC-Eca-033726	Equus caballus	52.96	0.00e+00	2086.00
IUUC-Eeu-034665	Erinaceus europaeus	50.28	3.00e-130	460.00
IUUC-Fca-035365	Felis catus	51.58	0.00e+00	2028.00
IUUC-Gmo-039584	Gadus morhua	30.73	1.00e-93	338.00
IUUC-Gac-042307	Gasterosteus aculeatus	34.63	0.00e+00	842.00
IUUC-Ggo-045432	Gorilla gorilla	50.77	0.00e+00	2004.00
IUUC-Hsa-046182	Homo sapiens	52.69	0.00e+00	2106.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	51.45	0.00e+00	2080.00
IUUC-Lch-050186	Latimeria chalumnae	32.65	3.00e-57	215.00
IUUC-Laf-054524	Loxodonta africana	52.09	0.00e+00	2147.00
IUUC-Mcc-055628	Macaca mulatta	53.26	0.00e+00	2120.00
IUUC-Meu-056338	Macropus eugenii	52.93	0.00e+00	986.00
IUUC-Mmr-060854	Microcebus murinus	53.50	0.00e+00	2139.00
IUUC-Mdo-062247	Monodelphis domestica	51.74	0.00e+00	2056.00
IUUC-Mmu-064406	Mus musculus	50.43	0.00e+00	1987.00
IUUC-Mpu-065806	Mustela putorius furo	52.08	0.00e+00	2079.00
IUUC-Mlu-068116	Myotis lucifugus	52.73	0.00e+00	1987.00
IUUC-Nle-069628	Nomascus leucogenys	53.80	0.00e+00	1900.00
IUUC-Opr-070242	Ochotona princeps	50.97	0.00e+00	1597.00
IUUC-Ocu-073933	Oryctolagus cuniculus	52.95	0.00e+00	2093.00
IUUC-Ola-086886	Oryzias latipes	32.77	0.00e+00	838.00
IUUC-Oga-088609	Otolemur garnettii	51.26	0.00e+00	2023.00
IUUC-Oar-089957	Ovis aries	51.92	0.00e+00	1978.00
IUUC-Ptr-090577	Pan troglodytes	51.41	0.00e+00	2045.00
IUUC-Pan-092397	Papio anubis	52.96	0.00e+00	2099.00
IUUC-Pma-094373	Petromyzon marinus	35.48	2.00e-28	120.00
IUUC-Pfo-096497	Poecilia formosa	34.31	0.00e+00	882.00
IUUC-Pab-098028	Pongo abelii	52.33	0.00e+00	2102.00
IUUC-Pca-101002	Procavia capensis	57.40	0.00e+00	1204.00
IUUC-Pva-102144	Pteropus vampyrus	50.95	0.00e+00	813.00
IUUC-Rno-105828	Rattus norvegicus	50.75	0.00e+00	2024.00
IUUC-Sha-106469	Sarcophilus harrisii	51.78	0.00e+00	2065.00
IUUC-Sar-113035	Sorex araneus	54.81	0.00e+00	937.00
IUUC-Ssc-116122	Sus scrofa	52.70	0.00e+00	1697.00
IUUC-Tru-118412	Takifugu rubripes	31.88	0.00e+00	1017.00
IUUC-Tsy-119257	Tarsius syrichta	46.71	0.00e+00	872.00
IUUC-Tni-120032	Tetraodon nigroviridis	34.81	2.00e-44	172.00
IUUC-Tbe-127312	Tupaia belangeri	41.26	1.00e-100	362.00
IUUC-Ttr-128335	Tursiops truncatus	51.67	0.00e+00	1986.00
IUUC-Xtr-132524	Xenopus tropicalis	38.85	0.00e+00	1040.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence