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Tag Content
UUCD2 ID IUUC-Ssc-115688
UUCD1 version UUC-SuS-00847
Ensembl Protein ID ENSSSCP00000012190.2
UniProt Accession F1SIW6; F1SIW6_PIG
Genbank Protein ID JAA53730.1
Protein Name Ubiquitin carboxyl-terminal hydrolase
Genbank Nucleotide ID CU550676
Gene Name BAP1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000011438.3 ENSSSCT00000012518.3 ENSSSCP00000012190.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/UCH 3.10e-170 566.4 3 729
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/UCH
   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           k+wleLesdPglftllvedfgvk++ qvee+y+L++++    q+pv+g+++lFk++e+r+s+rk++++++d++v+d+di++++ffa+q+
   Q: 3    KGWLELESDPGLFTLLVEDFGVKGV-QVEEIYDLQSKC----QGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQL 86
           89***********************.************....*********************************************** PP
   S: 95   igNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsy 183
           i+NsCat+Allsvllnc+++  dlG+tlsr+k++tk++spe+k++a+gn+++l+++hns+ar+e+r++pe+q+++++++t+eafhfvsy
   Q: 87   IPNSCATHALLSVLLNCSSV--DLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSY 173
           ********************..******************************************************************* PP
   S: 184  vningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid......... 259
           v+i+grl+eldglk++P+d+g+++e+ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr+++++rl+vlk++         
   Q: 174  VPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRIKYEARLHVLKVNrqtileslq 260
           *************************************..************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 261  qlirvtqpeliqthksqesqlpeeskpvssksplsveanrasvasegthtdgveevagscpqalthsppskpklmvkppgsslngvppn 349
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 350  ptpivqrlpafldnhnyakspmqeeedlaagvgrsrvpirppqqysddeddyeddeeddmqntnsairykrkgpgkpgplsgsgdgqls 438
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 439  vlqpntinvlaeklkesqkdlsiplsiktssgagspavavpthsqpsptpsnestdtaseigsafnsplrspirsanptrpsspvtshi 527
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 528  skvlfgeddsllrvdcirynravrdlgpvistgllhlaedgvlsplaltesgkgsspsvrlsqsshgsgspeekdmveamdgrekpglv 616
           ***************************************************************************************** PP
   S: 260  .............keLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveetisevrefgvn 335
                        keLl+Llk++e+e++++ea+l++e+ekrkkfkidd+rRt+nydefic+fi++la+eg+l++lve++is++r++gv+
   Q: 617  rpgeplsgekyspKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVS 705
           ***************************************************************************************** PP
   S: 336  egrlakqrkqgrekkirplkrkrk 359
           +grl+kqrk++r+k++rp+k+kr+
   Q: 706  IGRLHKQRKPDRRKRSRPYKAKRQ 729
           **********************97 PP
   
Organism Sus scrofa
Protein Sequence
(Fasta)
MNKGWLELES DPGLFTLLVE DFGVKGVQVE EIYDLQSKCQ GPVYGFIFLF KWIEERRSRR 60
KVSTLVDDTS VIDDDIVNNM FFAHQLIPNS CATHALLSVL LNCSSVDLGP TLSRMKDFTK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-115688|DUB,UCH|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCTGAGGGGC CGCCCCGCGG GAAGATGAAT AAGGGCTGGC TGGAGCTGGA GAGCGACCCT 60
GGTGAGGAGG GGACTGGGCA GGCCGGGAGC TGGGGAGGCC GGGTGGGTCC GGGATGCGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-115688|DUB,UCH|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
Interpro

IPR001578--Peptidase_C12_UCH
Pfam

PF01088--Peptidase_C12
PRINTS

PR00707--UBCTHYDRLASE
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0035517--C:PR-DUB complex
GO:0003682--F:chromatin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0061519--P:macrophage homeostasis
GO:0035522--P:monoubiquitinated histone H2A deubiquitination
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0051726--P:regulation of cell cycle
GO:0001558--P:regulation of cell growth
GO:1900015--P:regulation of cytokine production involved in inflammatory response
GO:0010035--P:response to inorganic substance
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG ssc:100154798
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001263 Ailuropoda melanoleuca 93.61 0.00e+00 1215.00
IUUC-Apl-003405 Anas platyrhynchos 68.86 0.00e+00 631.00
IUUC-Aca-004836 Anolis carolinensis 79.81 0.00e+00 1150.00
IUUC-Ame-011946 Astyanax mexicanus 63.31 0.00e+00 887.00
IUUC-Bta-013131 Bos taurus 91.98 0.00e+00 1082.00
IUUC-Cja-019599 Callithrix jacchus 95.06 0.00e+00 1322.00
IUUC-Cfa-021003 Canis familiaris 96.02 0.00e+00 1219.00
IUUC-Cpo-022143 Cavia porcellus 94.51 0.00e+00 1291.00
IUUC-Csa-023477 Chlorocebus sabaeus 94.79 0.00e+00 1293.00
IUUC-Cho-024734 Choloepus hoffmanni 81.64 0.00e+00 759.00
IUUC-Csv-025842 Ciona savignyi 58.60 3.00e-93 334.00
IUUC-Dre-027793 Danio rerio 65.89 0.00e+00 915.00
IUUC-Dno-029253 Dasypus novemcinctus 93.91 0.00e+00 1284.00
IUUC-Dor-030891 Dipodomys ordii 87.79 0.00e+00 1204.00
IUUC-Dme-031796 Drosophila melanogaster 60.45 6.00e-92 330.00
IUUC-Ete-032646 Echinops telfairi 86.52 2.00e-173 602.00
IUUC-Eca-033805 Equus caballus 95.34 0.00e+00 1269.00
IUUC-Eeu-035216 Erinaceus europaeus 93.20 6.00e-151 527.00
IUUC-Fca-035611 Felis catus 95.40 0.00e+00 1169.00
IUUC-Fal-037186 Ficedula albicollis 79.42 0.00e+00 994.00
IUUC-Gmo-038824 Gadus morhua 69.23 3.00e-180 624.00
IUUC-Gga-040875 Gallus gallus 81.23 0.00e+00 1117.00
IUUC-Gac-042226 Gasterosteus aculeatus 68.25 0.00e+00 938.00
IUUC-Ggo-045122 Gorilla gorilla 94.38 0.00e+00 1321.00
IUUC-Hsa-045882 Homo sapiens 94.65 0.00e+00 1323.00
IUUC-Itr-048185 Ictidomys tridecemlineatus 95.75 0.00e+00 1307.00
IUUC-Lch-049960 Latimeria chalumnae 72.36 0.00e+00 1001.00
IUUC-Loc-052408 Lepisosteus oculatus 74.89 0.00e+00 652.00
IUUC-Laf-054187 Loxodonta africana 95.75 0.00e+00 1254.00
IUUC-Mcc-055273 Macaca mulatta 93.83 0.00e+00 1290.00
IUUC-Meu-056267 Macropus eugenii 82.44 0.00e+00 1169.00
IUUC-Mga-059958 Meleagris gallopavo 87.58 4.00e-154 536.00
IUUC-Mmr-061280 Microcebus murinus 94.79 0.00e+00 1269.00
IUUC-Mdo-062625 Monodelphis domestica 88.89 0.00e+00 1272.00
IUUC-Mmu-063853 Mus musculus 92.32 0.00e+00 1274.00
IUUC-Mlu-067771 Myotis lucifugus 95.20 0.00e+00 1251.00
IUUC-Opr-070741 Ochotona princeps 92.32 0.00e+00 1275.00
IUUC-Ont-072172 Oreochromis niloticus 66.84 0.00e+00 949.00
IUUC-Oan-073167 Ornithorhynchus anatinus 79.56 0.00e+00 1136.00
IUUC-Ocu-074176 Oryctolagus cuniculus 94.91 0.00e+00 1241.00
IUUC-Ola-087203 Oryzias latipes 85.61 3.00e-135 474.00
IUUC-Oga-089153 Otolemur garnettii 94.32 0.00e+00 1280.00
IUUC-Oar-090008 Ovis aries 92.73 0.00e+00 1244.00
IUUC-Ptr-091234 Pan troglodytes 94.65 0.00e+00 1326.00
IUUC-Pan-092005 Papio anubis 94.79 0.00e+00 1320.00
IUUC-Psi-093995 Pelodiscus sinensis 83.42 0.00e+00 658.00
IUUC-Pma-094110 Petromyzon marinus 47.56 8.00e-120 424.00
IUUC-Pfo-097418 Poecilia formosa 65.84 0.00e+00 929.00
IUUC-Pab-098267 Pongo abelii 94.79 0.00e+00 1303.00
IUUC-Pca-101084 Procavia capensis 92.99 0.00e+00 1206.00
IUUC-Pva-102292 Pteropus vampyrus 96.31 0.00e+00 919.00
IUUC-Rno-105251 Rattus norvegicus 90.57 0.00e+00 1242.00
IUUC-Sha-107100 Sarcophilus harrisii 87.78 0.00e+00 1269.00
IUUC-Sar-113559 Sorex araneus 87.21 0.00e+00 1085.00
IUUC-Tgu-117424 Taeniopygia guttata 80.36 0.00e+00 1117.00
IUUC-Tru-118585 Takifugu rubripes 68.16 0.00e+00 931.00
IUUC-Tsy-119299 Tarsius syrichta 84.11 0.00e+00 984.00
IUUC-Tni-120808 Tetraodon nigroviridis 67.60 0.00e+00 929.00
IUUC-Tbe-127705 Tupaia belangeri 94.35 0.00e+00 627.00
IUUC-Ttr-128225 Tursiops truncatus 95.06 0.00e+00 1251.00
IUUC-Vpa-130193 Vicugna pacos 94.95 2.00e-131 462.00
IUUC-Xtr-132449 Xenopus tropicalis 70.06 0.00e+00 939.00
IUUC-Xma-133232 Xiphophorus maculatus 65.35 0.00e+00 922.00
Created Date 25-Jun-2017

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