iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059218

UUCD1 version

UUC-MeG-00062

Ensembl Protein ID

ENSMGAP00000000725.1

UniProt Accession

G1MRC8; G1MRC8_MELGA

Protein Name

Uncharacterized protein

Gene Name

WDR59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000001290.1	ENSMGAT00000001371.1	ENSMGAP00000000725.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-19	68.9	173	207

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           H +++++l++ +d   +l+++s D++++ WD+r+ 
   Q: 173  HLSKIHGLDWhPDneYTLATSSQDNSVRFWDYRQP 207
           99*********665577**************9876 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

QATAMSVDCL GQHAVLSGRR FLYIVNLDAP NEGHRKISRQ SKWDIGAVQW NPHDSYAYYF 60
AASSNQRVDL YKWKEGNGEV CTSLQGHTRV ISDLDWSVFE PDLLVTSSVD TYIYIWDIKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCAACTG CTATGTCAGT GGACTGCCTG GGACAGCACG CAGTACTCTC AGGGTGAGTG 60
TGACAATCCC CATTACAAGT GCATGACAGT CACTTCCACA AACCAAATCA GCAACCTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00591--RWD
SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002149	Ailuropoda melanoleuca	88.92	0.00e+00	1737.00
IUUC-Apl-004021	Anas platyrhynchos	97.81	0.00e+00	1847.00
IUUC-Aca-004977	Anolis carolinensis	85.76	0.00e+00	1689.00
IUUC-Ago-007961	Ashbya gossypii	25.45	1.00e-60	228.00
IUUC-Acl-008161	Aspergillus clavatus	24.62	2.00e-64	241.00
IUUC-Afl-008686	Aspergillus flavus	25.61	4.00e-63	236.00
IUUC-Afu-008932	Aspergillus fumigatus	28.78	5.00e-57	216.00
IUUC-Ani-009493	Aspergillus nidulans	29.24	2.00e-61	231.00
IUUC-Ang-009876	Aspergillus niger	34.57	9.00e-53	202.00
IUUC-Aor-009926	Aspergillus oryzae	25.61	4.00e-63	236.00
IUUC-Ate-010274	Aspergillus terreus	33.96	5.00e-51	196.00
IUUC-Ame-011297	Astyanax mexicanus	70.74	0.00e+00	1393.00
IUUC-Bgr-012173	Blumeria graminis	31.66	6.00e-45	176.00
IUUC-Bta-013261	Bos taurus	88.19	0.00e+00	1727.00
IUUC-Bci-013971	Botrytis cinerea	32.83	2.00e-46	181.00
IUUC-Cja-019167	Callithrix jacchus	87.46	0.00e+00	1710.00
IUUC-Cfa-020287	Canis familiaris	88.40	0.00e+00	1721.00
IUUC-Cpo-022510	Cavia porcellus	86.46	0.00e+00	1662.00
IUUC-Csa-023474	Chlorocebus sabaeus	86.99	0.00e+00	1742.00
IUUC-Cho-024634	Choloepus hoffmanni	89.01	0.00e+00	701.00
IUUC-Cin-025642	Ciona intestinalis	33.07	3.00e-137	482.00
IUUC-Csv-025848	Ciona savignyi	46.12	6.00e-56	209.00
IUUC-Cgl-026531	Colletotrichum gloeosporioides	32.48	3.00e-45	177.00
IUUC-Cne-027088	Cryptococcus neoformans	31.80	9.00e-45	175.00
IUUC-Dre-028753	Danio rerio	71.21	0.00e+00	1357.00
IUUC-Dno-029733	Dasypus novemcinctus	88.10	0.00e+00	1714.00
IUUC-Dor-030781	Dipodomys ordii	88.65	0.00e+00	887.00
IUUC-Dme-031803	Drosophila melanogaster	33.74	1.00e-148	520.00
IUUC-Ete-032622	Echinops telfairi	81.26	0.00e+00	1525.00
IUUC-Eca-033344	Equus caballus	89.24	0.00e+00	1732.00
IUUC-Eeu-034523	Erinaceus europaeus	79.92	0.00e+00	1510.00
IUUC-Fca-035650	Felis catus	88.92	0.00e+00	1735.00
IUUC-Fal-037404	Ficedula albicollis	97.59	0.00e+00	1897.00
IUUC-Fox-037955	Fusarium oxysporum	34.17	1.00e-44	175.00
IUUC-Fso-038289	Fusarium solani	33.44	2.00e-47	184.00
IUUC-Gmo-038547	Gadus morhua	67.21	0.00e+00	1347.00
IUUC-Ggr-039858	Gaeumannomyces graminis	36.46	2.00e-44	174.00
IUUC-Gga-041030	Gallus gallus	99.58	0.00e+00	1898.00
IUUC-Gac-042581	Gasterosteus aculeatus	70.05	0.00e+00	1396.00
IUUC-Ggo-044641	Gorilla gorilla	88.71	0.00e+00	1737.00
IUUC-Hsa-046134	Homo sapiens	88.92	0.00e+00	1738.00
IUUC-Itr-048551	Ictidomys tridecemlineatus	89.40	0.00e+00	697.00
IUUC-Kpa-049091	Komagataella pastoris	33.02	6.00e-45	176.00
IUUC-Lch-050288	Latimeria chalumnae	76.40	0.00e+00	1466.00
IUUC-Loc-052802	Lepisosteus oculatus	74.39	0.00e+00	1462.00
IUUC-Lma-053296	Leptosphaeria maculans	32.80	3.00e-47	184.00
IUUC-Laf-053997	Loxodonta africana	87.50	0.00e+00	1759.00
IUUC-Mcc-055855	Macaca mulatta	88.71	0.00e+00	1721.00
IUUC-Meu-056898	Macropus eugenii	88.35	0.00e+00	679.00
IUUC-Mor-056913	Magnaporthe oryzae	35.69	3.00e-44	174.00
IUUC-Mpo-057612	Magnaporthe poae	37.55	1.00e-45	177.00
IUUC-Mla-059097	Melampsora laricipopulina	30.06	5.00e-46	179.00
IUUC-Mvi-060251	Microbotryum violaceum	31.46	5.00e-46	179.00
IUUC-Mmr-061093	Microcebus murinus	85.67	0.00e+00	1670.00
IUUC-Mdo-062757	Monodelphis domestica	87.07	0.00e+00	1712.00
IUUC-Mmu-063839	Mus musculus	86.37	0.00e+00	1738.00
IUUC-Mpu-065977	Mustela putorius furo	88.61	0.00e+00	1726.00
IUUC-Mlu-067460	Myotis lucifugus	86.80	0.00e+00	1717.00
IUUC-Nfi-068250	Neosartorya fischeri	29.27	8.00e-60	225.00
IUUC-Ncr-068710	Neurospora crassa	33.65	8.00e-46	179.00
IUUC-Nle-070011	Nomascus leucogenys	88.61	0.00e+00	1730.00
IUUC-Opr-070731	Ochotona princeps	82.24	0.00e+00	1569.00
IUUC-Ont-072165	Oreochromis niloticus	70.14	0.00e+00	1379.00
IUUC-Oan-072887	Ornithorhynchus anatinus	88.45	0.00e+00	1782.00
IUUC-Ocu-073926	Oryctolagus cuniculus	85.89	0.00e+00	1570.00
IUUC-Ola-087111	Oryzias latipes	66.60	0.00e+00	1308.00
IUUC-Oga-088850	Otolemur garnettii	88.61	0.00e+00	1730.00
IUUC-Oar-090291	Ovis aries	87.98	0.00e+00	1724.00
IUUC-Ptr-091044	Pan troglodytes	88.61	0.00e+00	1727.00
IUUC-Pan-092374	Papio anubis	86.78	0.00e+00	1737.00
IUUC-Psi-093170	Pelodiscus sinensis	56.60	0.00e+00	976.00
IUUC-Pma-094544	Petromyzon marinus	69.64	2.00e-174	604.00
IUUC-Pno-095068	Phaeosphaeria nodorum	31.08	3.00e-43	171.00
IUUC-Pfo-096480	Poecilia formosa	68.49	0.00e+00	1330.00
IUUC-Pab-098134	Pongo abelii	87.36	0.00e+00	1697.00
IUUC-Pca-100763	Procavia capensis	68.59	0.00e+00	889.00
IUUC-Pva-102544	Pteropus vampyrus	87.57	0.00e+00	1723.00
IUUC-Pgr-103257	Puccinia graminis	32.70	1.00e-48	188.00
IUUC-Ptt-103942	Puccinia triticina	31.51	2.00e-44	174.00
IUUC-Pte-104065	Pyrenophora teres	32.08	1.00e-44	176.00
IUUC-Rno-105468	Rattus norvegicus	84.04	0.00e+00	1561.00
IUUC-Sce-106356	Saccharomyces cerevisiae	29.01	2.00e-58	221.00
IUUC-Sha-106662	Sarcophilus harrisii	89.35	0.00e+00	1744.00
IUUC-Sja-107973	Schizosaccharomyces japonicus	28.06	3.00e-72	266.00
IUUC-Spo-108265	Schizosaccharomyces pombe	34.05	3.00e-49	190.00
IUUC-Ssl-108662	Sclerotinia sclerotiorum	33.43	8.00e-46	179.00
IUUC-Sar-113525	Sorex araneus	86.08	0.00e+00	989.00
IUUC-Sre-115163	Sporisorium reilianum	36.65	3.00e-40	160.00
IUUC-Ssc-115381	Sus scrofa	87.43	0.00e+00	943.00
IUUC-Tgu-116525	Taeniopygia guttata	93.10	0.00e+00	1784.00
IUUC-Tru-118432	Takifugu rubripes	68.50	0.00e+00	1369.00
IUUC-Tsy-119306	Tarsius syrichta	74.06	0.00e+00	1095.00
IUUC-Tni-120757	Tetraodon nigroviridis	68.74	0.00e+00	1332.00
IUUC-Tre-122187	Trichoderma reesei	35.99	4.00e-49	190.00
IUUC-Tvi-122367	Trichoderma virens	36.42	3.00e-49	190.00
IUUC-Tme-126986	Tuber melanosporum	34.70	4.00e-54	206.00
IUUC-Tbe-127800	Tupaia belangeri	75.77	0.00e+00	1261.00
IUUC-Ttr-129154	Tursiops truncatus	80.13	0.00e+00	1546.00
IUUC-Uma-129366	Ustilago maydis	35.57	2.00e-39	157.00
IUUC-Vda-129827	Verticillium dahliae	34.18	2.00e-48	188.00
IUUC-Vpa-130493	Vicugna pacos	88.39	0.00e+00	1714.00
IUUC-Xtr-131941	Xenopus tropicalis	81.09	0.00e+00	1568.00
IUUC-Xma-133903	Xiphophorus maculatus	69.67	0.00e+00	1365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence