iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005140

Ensembl Protein ID

ENSACAP00000017614.3

UniProt Accession

G1KUG7; G1KUG7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

WDR49

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000017891.3	ENSACAT00000017960.3	ENSACAP00000017614.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-15	55.9	610	642
UBD/Beta-Prp	5.70e-45	153.7	299	593

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrt 32
           +H++++ c af +  +l++Gs  g i vW+ +t
   Q: 610  QHQEDILCAAFlPPQTLATGSSGGEIVVWNNST 642
           599********955889************9665 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgh....eaevtavkfspdgkilvtgseDrtikvw.dlstgkcvhtlk 91
           h+k+ ++ v++s + +++++ s+++t ++  + ++kl ++l       +++v+a +f+p+ ++++t++    +++w ++ t+k++  l+
   Q: 299  HDKEWVRQVAYSSSLDVFISISTSSTNTLVLAWREKLSHRLTMTtfhiTQGVNAFDFHPRLNLIATAGINCRVCLWnPYVTSKPTGFLE 387
           455556666666666666665555554433333335555553331112466*************************6777********* PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtlt 176
           gh+d v +++f  +++ l s  +d+++r+wd++ + c++     + +  ++ +++ ++++  +l++  sl++++ l  +++++  r+ +
   Q: 388  GHSDCVIAVQFILERKLLFSFAKDKVLRIWDIQYQLCIQRiagSFPKSIDFHSVLYFDESHgRLFI--SLNNQLTLLEMEQESGNRRVK 474
           ***************************************999977788889999999999988888..5999999************** PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng.ht.dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           + h ++v+++ ++s  k+++s ++ +tv++w + tg+ +++++  h  + ++ ++++  ++rl +g++Dg +++Wd  +g + ++l+  
   Q: 475  S-HRKPVTCILYNSVFKQVISSDTASTVIFWLIDTGQKIKEFTScHGnAEINTMALDGTETRLFTGGMDGIVKVWD-FNGHCHHKLNVG 561
           9.***************************************9874433889************************9.79********** PP
   S: 264  nssvisvav.lsfgdnvlvlgsedskvniwklk 295
           +++ + ++  l ++  +lvlg+ d ++ ++ l+
   Q: 562  RDRTVEISQiLVLSWTILVLGG-DRSITVFWLN 593
           *888877764666666666665.5666666555 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MDKTAEQPPN RTKETGMARN LEQLENRLTI HDFRKMQGLF KSPGSKKIKG MMAKEEFMDK 60
MSTNIRQGTK EEYGELFSKI DLNRDGAIDW EKLTSFLLLE LYERDERTKL SVIPQWKDLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCCAGCAA CTCCAAACAG CCCTAGAAAT GCTCTTAGTG TCAACTTTGT ACTCAGAAGC 60
AGGGAGTTTC TGAAGTTAAT TGTGTGTGTT CAGCAAAGAT AATGGAATTT TAATCAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011992--EF-hand-dom_pair
IPR002048--EF_hand_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50222--EF_HAND_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005509--F:calcium ion binding

KEGG

acs:100555654

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002386	Ailuropoda melanoleuca	61.59	0.00e+00	991.00
IUUC-Ame-011677	Astyanax mexicanus	55.91	4.00e-118	417.00
IUUC-Bta-013449	Bos taurus	53.50	0.00e+00	706.00
IUUC-Cja-019381	Callithrix jacchus	53.77	0.00e+00	696.00
IUUC-Cfa-020449	Canis familiaris	54.83	0.00e+00	1097.00
IUUC-Csa-023219	Chlorocebus sabaeus	46.98	7.00e-119	420.00
IUUC-Cho-024437	Choloepus hoffmanni	71.10	6.00e-90	325.00
IUUC-Cin-025263	Ciona intestinalis	42.93	0.00e+00	817.00
IUUC-Csv-026326	Ciona savignyi	27.61	7.00e-46	178.00
IUUC-Dre-027573	Danio rerio	27.21	2.00e-72	267.00
IUUC-Dno-029512	Dasypus novemcinctus	53.62	0.00e+00	1042.00
IUUC-Dor-030182	Dipodomys ordii	61.12	5.00e-167	580.00
IUUC-Dme-031984	Drosophila melanogaster	22.16	3.00e-42	167.00
IUUC-Ete-033152	Echinops telfairi	51.28	0.00e+00	657.00
IUUC-Eca-033848	Equus caballus	54.62	3.00e-109	387.00
IUUC-Eeu-034535	Erinaceus europaeus	44.25	1.00e-140	493.00
IUUC-Fca-036363	Felis catus	60.88	0.00e+00	972.00
IUUC-Gmo-039551	Gadus morhua	31.85	2.00e-33	136.00
IUUC-Gac-042429	Gasterosteus aculeatus	40.34	2.00e-85	309.00
IUUC-Ggo-045225	Gorilla gorilla	54.68	0.00e+00	767.00
IUUC-Hsa-046739	Homo sapiens	54.53	0.00e+00	717.00
IUUC-Itr-047862	Ictidomys tridecemlineatus	61.63	0.00e+00	629.00
IUUC-Lch-049722	Latimeria chalumnae	54.42	0.00e+00	1102.00
IUUC-Loc-052665	Lepisosteus oculatus	52.21	0.00e+00	1058.00
IUUC-Laf-054050	Loxodonta africana	50.69	2.00e-159	555.00
IUUC-Mcc-054635	Macaca mulatta	28.05	4.00e-63	236.00
IUUC-Meu-056792	Macropus eugenii	52.02	8.00e-142	497.00
IUUC-Mmr-060714	Microcebus murinus	62.12	1.00e-180	625.00
IUUC-Mdo-062938	Monodelphis domestica	60.15	0.00e+00	632.00
IUUC-Mmu-063645	Mus musculus	52.01	0.00e+00	703.00
IUUC-Mpu-066015	Mustela putorius furo	54.75	0.00e+00	1074.00
IUUC-Mlu-068140	Myotis lucifugus	53.60	0.00e+00	653.00
IUUC-Nle-069533	Nomascus leucogenys	53.67	0.00e+00	671.00
IUUC-Opr-070439	Ochotona princeps	47.50	2.00e-148	519.00
IUUC-Ont-072106	Oreochromis niloticus	26.71	3.00e-72	266.00
IUUC-Oan-073400	Ornithorhynchus anatinus	48.67	7.00e-79	286.00
IUUC-Ocu-074202	Oryctolagus cuniculus	60.99	0.00e+00	682.00
IUUC-Ola-086882	Oryzias latipes	41.22	3.00e-92	332.00
IUUC-Oga-087999	Otolemur garnettii	54.60	0.00e+00	874.00
IUUC-Oar-090438	Ovis aries	54.49	0.00e+00	1061.00
IUUC-Ptr-090859	Pan troglodytes	54.82	0.00e+00	697.00
IUUC-Pan-092049	Papio anubis	57.63	7.00e-144	503.00
IUUC-Psi-093625	Pelodiscus sinensis	62.57	0.00e+00	866.00
IUUC-Pma-094599	Petromyzon marinus	28.91	3.00e-55	209.00
IUUC-Pfo-096408	Poecilia formosa	28.09	4.00e-50	192.00
IUUC-Pab-098444	Pongo abelii	63.74	4.00e-167	580.00
IUUC-Pca-100464	Procavia capensis	43.47	1.00e-101	363.00
IUUC-Pva-102863	Pteropus vampyrus	51.67	0.00e+00	694.00
IUUC-Rno-105493	Rattus norvegicus	50.56	0.00e+00	664.00
IUUC-Sha-107206	Sarcophilus harrisii	49.15	1.00e-179	622.00
IUUC-Smo-109247	Selaginella moellendorffii	24.97	6.00e-36	146.00
IUUC-Sar-113119	Sorex araneus	40.10	5.00e-118	417.00
IUUC-Ssc-116181	Sus scrofa	61.78	0.00e+00	993.00
IUUC-Tru-118700	Takifugu rubripes	40.93	2.00e-83	302.00
IUUC-Tsy-119608	Tarsius syrichta	46.81	2.00e-171	595.00
IUUC-Tni-120461	Tetraodon nigroviridis	41.35	1.00e-85	309.00
IUUC-Tbe-127509	Tupaia belangeri	54.72	1.00e-166	579.00
IUUC-Ttr-128571	Tursiops truncatus	59.31	2.00e-153	535.00
IUUC-Vpa-130340	Vicugna pacos	50.96	0.00e+00	640.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence