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Tag Content
UUCD2 ID IUUC-Nle-070072
UUCD1 version UUC-NoL-00981
Ensembl Protein ID ENSNLEP00000003842.1
UniProt Accession G1QSC4; G1QSC4_NOMLE
Genbank Protein ID ENSNLEP00000003842
Protein Name Uncharacterized protein
Genbank Nucleotide ID ADFV01063432
Gene Name UBA1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSNLEG00000003096.2 ENSNLET00000004035.1 ENSNLEP00000003842.1
Status Unreviewed
Classification
Family E-Value Score Start End
E1 1.50e-209 696.3 451 931
Active Site
Position(s) Description Evidence
632 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU10132}
Domain Profile

   E1
   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD+Q++++G++ qekl+++k++lvGag++GcEllKn++++G+     g+i v+Dmdt+e+snlnrqFLfr++dv k K+++aa+a++++
   Q: 451  YDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLgcgegGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVHQM 539
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkt 170
           np+++v++h++++ +++e+i+   Ff+++d+V++aldn++ar++++r+c+++r+pl+esgtlG++G+v+v+i+ lte+ys+s+dpp+k+
   Q: 540  NPHIRVTSHQNRVGPDTERIYdddFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKS 628
           ***************************************************************************************** PP
   S: 171  iPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafak 247
           iP+ctlk++pna+eht++wa            + +n++l ++++++e++ +l+ ++++e++++v+++l+ ++++++++++++a++++++
   Q: 629  IPICTLKNFPNAIEHTLQWArdefeglfkqpaENVNQYL-TDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHT 716
           ***************************************.999999******************************************* PP
   S: 248  ttinsikqllksfecdivtkskspfwv..........................................sfcsnaealqvp........ 286
           +++n+i+qll++f++d++t+s++pfw+                                           + ++ +++qvp        
   Q: 717  QYSNNIRQLLHNFPPDQLTSSGAPFWSgpkrcphpltfdvnnplhldyvmaaanlfaqtygltgsqdraAVATLLQSVQVPeftpksgv 805
           *****************************************************************999966666666666655555555 PP
   S: 287  ekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipa 368
           + +++d+e ++a+a+     l+ l+++l + +k +g k++ ++fekddds  ++d++ aa+nlrae+++i+p +d+++ k iag+iipa
   Q: 806  KIHVSDQELQSANASvddsrLEELKATLPSPDKLPGFKMYPIDFEKDDDSnfHMDFIVAASNLRAENYDIPP-ADRHKSKLIAGKIIPA 893
           66666666666666688889****************************************************.**************** PP
   S: 369  iattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           iatt+a+v Gl+++E++Kvv+g  + + +kn fl++a+
   Q: 894  IATTTAAVVGLVCLELYKVVQGhrQLDSYKNGFLNLAL 931
           **********************999*********9875 PP
   
Organism Nomascus leucogenys
Protein Sequence
(Fasta)
MSSSPLSKKR RVSGPDPKPG SNCSPAQSVL SEVPSVPTNG MAKNGSEADI DEGLYSRQLS 60
GAKAGLRGVG WDIERIGLGG AGPDLDTFPP FPIPEAPPFL VPQPFHLFPY CTPLQFYLRE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Nle-070072|E1,E1_ThiF|Nomascus leucogenys
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCCAGCT CGCCGCTGTC CAAGAAACGT CGCGTGTCCG GGCCTGATCC AAAGCCGGGT 60
TCTAACTGCT CCCCTGCCCA GTCCGTGTTG TCCGAAGTGC CCTCGGTGCC AACCAACGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Nle-070072|E1,E1_ThiF|Nomascus leucogenys
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like
PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2
Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys
PRINTS

PR01849--UBIQUITINACT
SMART

SM00985--UBA_e1_C
Gene Ontology

GO:0005829--C:cytosol
GO:0030057--C:desmosome
GO:0010008--C:endosome membrane
GO:0070062--C:extracellular exosome
GO:0000792--C:heterochromatin
GO:0005765--C:lysosomal membrane
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0030867--C:rough endoplasmic reticulum membrane
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0004839--F:ubiquitin activating enzyme activity
GO:0006974--P:cellular response to DNA damage stimulus
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000367 Aegilops tauschii 43.74 0.00e+00 790.00
IUUC-Aml-001311 Ailuropoda melanoleuca 91.27 0.00e+00 1969.00
IUUC-Atr-002684 Amborella trichopoda 43.18 0.00e+00 823.00
IUUC-Aca-004620 Anolis carolinensis 76.68 0.00e+00 1675.00
IUUC-Aly-005515 Arabidopsis lyrata 42.91 0.00e+00 836.00
IUUC-Ath-006891 Arabidopsis thaliana 43.50 0.00e+00 847.00
IUUC-Ago-007873 Ashbya gossypii 52.21 0.00e+00 1003.00
IUUC-Acl-008181 Aspergillus clavatus 51.27 0.00e+00 1003.00
IUUC-Afl-008455 Aspergillus flavus 53.10 0.00e+00 978.00
IUUC-Afu-009065 Aspergillus fumigatus 50.93 0.00e+00 1009.00
IUUC-Ani-009371 Aspergillus nidulans 50.97 0.00e+00 989.00
IUUC-Ang-009737 Aspergillus niger 51.41 0.00e+00 1007.00
IUUC-Aor-010007 Aspergillus oryzae 53.10 0.00e+00 978.00
IUUC-Ate-010466 Aspergillus terreus 51.58 0.00e+00 1027.00
IUUC-Ame-010933 Astyanax mexicanus 75.14 0.00e+00 1576.00
IUUC-Bgr-012281 Blumeria graminis 50.98 0.00e+00 1012.00
IUUC-Bta-012767 Bos taurus 91.52 0.00e+00 1978.00
IUUC-Bci-013721 Botrytis cinerea 51.76 0.00e+00 959.00
IUUC-Bdi-014843 Brachypodium distachyon 43.15 0.00e+00 798.00
IUUC-Bol-015665 Brassica oleracea 41.82 0.00e+00 825.00
IUUC-Bra-017522 Brassica rapa 44.50 0.00e+00 826.00
IUUC-Cel-018260 Caenorhabditis elegans 47.09 0.00e+00 874.00
IUUC-Cja-019152 Callithrix jacchus 93.29 0.00e+00 2008.00
IUUC-Cfa-020622 Canis familiaris 90.21 0.00e+00 1897.00
IUUC-Cpo-022526 Cavia porcellus 91.89 0.00e+00 1956.00
IUUC-Cre-022702 Chlamydomonas reinhardtii 43.35 0.00e+00 772.00
IUUC-Csa-023780 Chlorocebus sabaeus 93.38 0.00e+00 2009.00
IUUC-Cho-024896 Choloepus hoffmanni 87.45 3.00e-118 419.00
IUUC-Cin-025790 Ciona intestinalis 60.23 0.00e+00 1273.00
IUUC-Csv-026084 Ciona savignyi 58.16 0.00e+00 1254.00
IUUC-Cgl-026512 Colletotrichum gloeosporioides 51.27 0.00e+00 1019.00
IUUC-Cne-026960 Cryptococcus neoformans 53.25 0.00e+00 1043.00
IUUC-Cme-027290 Cyanidioschyzon merolae 43.69 0.00e+00 793.00
IUUC-Dre-028149 Danio rerio 74.86 0.00e+00 1604.00
IUUC-Dno-028884 Dasypus novemcinctus 91.71 0.00e+00 1989.00
IUUC-Dor-030229 Dipodomys ordii 87.33 0.00e+00 1868.00
IUUC-Dse-031524 Dothistroma septosporum 49.95 0.00e+00 1010.00
IUUC-Dme-032045 Drosophila melanogaster 57.96 0.00e+00 1198.00
IUUC-Ete-032544 Echinops telfairi 96.12 0.00e+00 807.00
IUUC-Eca-033330 Equus caballus 92.54 0.00e+00 2001.00
IUUC-Fca-036255 Felis catus 92.54 0.00e+00 1972.00
IUUC-Fal-037445 Ficedula albicollis 49.51 0.00e+00 854.00
IUUC-Fox-038007 Fusarium oxysporum 54.19 2.00e-168 585.00
IUUC-Fso-038339 Fusarium solani 51.80 0.00e+00 990.00
IUUC-Gmo-039338 Gadus morhua 71.72 0.00e+00 1506.00
IUUC-Ggr-039823 Gaeumannomyces graminis 51.51 0.00e+00 1038.00
IUUC-Gga-040365 Gallus gallus 47.46 0.00e+00 819.00
IUUC-Gac-041773 Gasterosteus aculeatus 71.75 0.00e+00 1508.00
IUUC-Gma-043198 Glycine max 41.72 0.00e+00 803.00
IUUC-Ggo-045336 Gorilla gorilla 94.22 0.00e+00 2002.00
IUUC-Hsa-045982 Homo sapiens 94.04 0.00e+00 1996.00
IUUC-Hvu-047418 Hordeum vulgare 43.42 0.00e+00 808.00
IUUC-Itr-048460 Ictidomys tridecemlineatus 92.54 0.00e+00 1998.00
IUUC-Kpa-049112 Komagataella pastoris 49.61 0.00e+00 956.00
IUUC-Lch-050371 Latimeria chalumnae 75.98 0.00e+00 1664.00
IUUC-Lpe-051299 Leersia perrieri 42.36 0.00e+00 827.00
IUUC-Loc-052936 Lepisosteus oculatus 76.91 0.00e+00 1654.00
IUUC-Lma-053315 Leptosphaeria maculans 49.53 0.00e+00 1015.00
IUUC-Laf-053948 Loxodonta africana 89.38 0.00e+00 1926.00
IUUC-Mcc-055843 Macaca mulatta 93.66 0.00e+00 2019.00
IUUC-Meu-056258 Macropus eugenii 83.04 0.00e+00 1801.00
IUUC-Mor-057269 Magnaporthe oryzae 51.46 0.00e+00 1016.00
IUUC-Mpo-057435 Magnaporthe poae 51.66 0.00e+00 1004.00
IUUC-Mtr-058572 Medicago truncatula 41.51 0.00e+00 786.00
IUUC-Mla-059176 Melampsora laricipopulina 53.72 0.00e+00 1029.00
IUUC-Mga-060052 Meleagris gallopavo 50.24 0.00e+00 748.00
IUUC-Mvi-060437 Microbotryum violaceum 51.67 0.00e+00 1002.00
IUUC-Mmr-061405 Microcebus murinus 90.49 0.00e+00 1938.00
IUUC-Mdo-062032 Monodelphis domestica 84.22 0.00e+00 1828.00
IUUC-Mmu-063280 Mus musculus 90.59 0.00e+00 1942.00
IUUC-Mac-065505 Musa acuminata 43.58 0.00e+00 815.00
IUUC-Mpu-066409 Mustela putorius furo 92.36 0.00e+00 1996.00
IUUC-Mlu-067217 Myotis lucifugus 90.77 0.00e+00 1958.00
IUUC-Nfi-068407 Neosartorya fischeri 51.12 0.00e+00 998.00
IUUC-Ncr-068698 Neurospora crassa 52.52 0.00e+00 1030.00
IUUC-Ont-071671 Oreochromis niloticus 74.65 0.00e+00 1584.00
IUUC-Oan-073306 Ornithorhynchus anatinus 49.56 0.00e+00 723.00
IUUC-Ocu-074544 Oryctolagus cuniculus 91.99 0.00e+00 1990.00
IUUC-Oba-075120 Oryza barthii 43.17 0.00e+00 811.00
IUUC-Obr-076557 Oryza brachyantha 43.68 0.00e+00 804.00
IUUC-Ogl-077887 Oryza glaberrima 43.17 0.00e+00 813.00
IUUC-Ogu-078305 Oryza glumaepatula 41.75 0.00e+00 817.00
IUUC-Oin-079370 Oryza indica 42.83 0.00e+00 811.00
IUUC-Olo-081089 Oryza longistaminata 41.84 0.00e+00 818.00
IUUC-Ome-081942 Oryza meridionalis 43.17 0.00e+00 810.00
IUUC-Oni-082365 Oryza nivara 43.07 0.00e+00 812.00
IUUC-Opu-083977 Oryza punctata 43.33 0.00e+00 812.00
IUUC-Oru-084469 Oryza rufipogon 41.84 0.00e+00 821.00
IUUC-Osa-085949 Oryza sativa 43.47 0.00e+00 822.00
IUUC-Ola-087002 Oryzias latipes 73.80 0.00e+00 1572.00
IUUC-Olu-087687 Ostreococcus lucimarinus 41.91 0.00e+00 746.00
IUUC-Oga-088594 Otolemur garnettii 92.36 0.00e+00 1962.00
IUUC-Oar-090068 Ovis aries 91.25 0.00e+00 1972.00
IUUC-Pan-092114 Papio anubis 93.66 0.00e+00 2020.00
IUUC-Pno-095154 Phaeosphaeria nodorum 49.95 0.00e+00 1023.00
IUUC-Ppa-095416 Physcomitrella patens 43.32 0.00e+00 826.00
IUUC-Pfo-097184 Poecilia formosa 73.61 0.00e+00 1566.00
IUUC-Pab-097861 Pongo abelii 93.94 0.00e+00 1985.00
IUUC-Pop-098934 Populus trichocarpa 42.47 0.00e+00 845.00
IUUC-Pca-100347 Procavia capensis 91.87 0.00e+00 1649.00
IUUC-Ppe-102012 Prunus persica 42.12 0.00e+00 830.00
IUUC-Pva-102584 Pteropus vampyrus 92.36 0.00e+00 2011.00
IUUC-Pgr-103336 Puccinia graminis 52.35 0.00e+00 991.00
IUUC-Ptt-103939 Puccinia triticina 51.92 0.00e+00 996.00
IUUC-Pte-104200 Pyrenophora teres 50.53 0.00e+00 1014.00
IUUC-Pyt-104441 Pyrenophora triticirepentis 49.67 0.00e+00 1002.00
IUUC-Rno-105462 Rattus norvegicus 91.52 0.00e+00 1935.00
IUUC-Sce-106245 Saccharomyces cerevisiae 50.05 0.00e+00 1017.00
IUUC-Sha-107142 Sarcophilus harrisii 82.95 0.00e+00 1816.00
IUUC-Sja-107841 Schizosaccharomyces japonicus 53.52 0.00e+00 1074.00
IUUC-Spo-108034 Schizosaccharomyces pombe 51.53 0.00e+00 1009.00
IUUC-Ssl-108497 Sclerotinia sclerotiorum 51.75 0.00e+00 978.00
IUUC-Smo-109211 Selaginella moellendorffii 43.60 0.00e+00 819.00
IUUC-Sit-110281 Setaria italica 43.34 0.00e+00 826.00
IUUC-Sly-110914 Solanum lycopersicum 42.18 0.00e+00 827.00
IUUC-Stu-112109 Solanum tuberosum 42.27 0.00e+00 835.00
IUUC-Sar-113737 Sorex araneus 91.15 0.00e+00 1964.00
IUUC-Sbi-114520 Sorghum bicolor 42.97 0.00e+00 824.00
IUUC-Sre-115148 Sporisorium reilianum 52.78 0.00e+00 1025.00
IUUC-Ssc-115777 Sus scrofa 92.46 0.00e+00 1993.00
IUUC-Tru-118742 Takifugu rubripes 73.61 0.00e+00 1519.00
IUUC-Tni-120401 Tetraodon nigroviridis 74.43 0.00e+00 1522.00
IUUC-Tca-121672 Theobroma cacao 42.31 0.00e+00 831.00
IUUC-Tre-122009 Trichoderma reesei 50.97 0.00e+00 970.00
IUUC-Tvi-122259 Trichoderma virens 51.27 0.00e+00 966.00
IUUC-Tae-125113 Triticum aestivum 43.78 0.00e+00 791.00
IUUC-Tur-126189 Triticum urartu 43.34 0.00e+00 788.00
IUUC-Tme-127055 Tuber melanosporum 51.27 0.00e+00 946.00
IUUC-Tbe-127487 Tupaia belangeri 86.57 0.00e+00 924.00
IUUC-Ttr-128331 Tursiops truncatus 91.52 0.00e+00 1964.00
IUUC-Uma-129387 Ustilago maydis 52.99 0.00e+00 1027.00
IUUC-Vda-129977 Verticillium dahliae 51.12 0.00e+00 935.00
IUUC-Vvi-130857 Vitis vinifera 42.70 0.00e+00 832.00
IUUC-Xtr-132026 Xenopus tropicalis 60.56 0.00e+00 1171.00
IUUC-Xma-133805 Xiphophorus maculatus 73.42 0.00e+00 1543.00
IUUC-Yli-134547 Yarrowia lipolytica 51.38 0.00e+00 1025.00
IUUC-Zma-135052 Zea mays 43.22 0.00e+00 828.00
Created Date 25-Jun-2017

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