iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053751

UUCD1 version

UUC-LoA-00364

Ensembl Protein ID

ENSLAFP00000009023.2

UniProt Accession

G3T693; G3T693_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TBL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000010783.2	ENSLAFT00000031547.1	ENSLAFP00000018039.1
ENSLAFG00000010783.2	ENSLAFT00000010784.2	ENSLAFP00000009023.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-20	70.3	89	122
UBD/Beta-Prp	3.30e-48	164.7	77	309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H++ ++c++f s+ ++l++++dD t+++W+++++
   Q: 89   HSGNISCMDFsSNgKYLATCADDRTVRIWSTKDF 122
           9**********777***************98775 PP

UBD/Beta-Prp

   S: 39   vttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcvhtlkghedsvlslsfspsg.dklvsGshdrtirvwd 122
           +t   l + l++h++ +++++fs++gk+l+t+++Drt+++w+ +         +  + + d +++++fsp+   ++v   + +t+rv++
   Q: 77   FTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKdflqREHRSMRANVELDHATLVRFSPDCrAFIVWLASGDTLRVFK 165
           5666678899*******************************7773433333333344678999*******65599**99999******* PP
   S: 123  letgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgt 203
           +++++            + ++h++ +  + + ++g+ ++++s D+tv +W+l  g++l t    ++    + ++++ +++++s++   +
   Q: 166  MNKREDGGYtfaatpedFPKKHKAPIVNIGIADTGKFIMTASSDTTVLIWNL-KGRVLSTINT-NQMNNAHAAISPCSRFVASCGFTPD 252
           *998766556788999999*********************************.7888888877.7777888889999************ PP
   S: 204  vklwdlqtgec........vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
           vk+w++  g+           +l+gh++ v   +fs+++ r++s+s+Dg+ ++Wd++
   Q: 253  VKVWEVCFGKKgdfqevvrAFELKGHSAAVHFFAFSNDSRRMASVSKDGTWKLWDTD 309
           ******955555557777788999******************************965 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MELPQMPELV GLSLLLGLLA LVATAAVARG WLRTEDEARG RRAGQKGNGF PPVKSLGSKK 60
QKLHQRIRRE KPQQHSFTHR LLAAALKSHS GNISCMDFSS NGKYLATCAD DRTVRIWSTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCTAC CGCAGATGCC GGAGCTCGTG GGCCTGTCGC TCTTGTTGGG GCTGCTGGCC 60
CTGGTGGCGA CGGCGGCGGT GGCGCGGGGG TGGCTGCGCA CGGAGGACGA GGCGCGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0003723--F:RNA binding
GO:0042149--P:cellular response to glucose starvation
GO:0071456--P:cellular response to hypoxia
GO:0030968--P:endoplasmic reticulum unfolded protein response

KEGG

lav:100667614

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000109	Aegilops tauschii	32.68	1.00e-22	99.40
IUUC-Aml-002212	Ailuropoda melanoleuca	89.91	0.00e+00	745.00
IUUC-Atr-002903	Amborella trichopoda	29.29	3.00e-36	145.00
IUUC-Apl-003635	Anas platyrhynchos	75.93	2.00e-164	571.00
IUUC-Aca-004472	Anolis carolinensis	75.20	2.00e-164	571.00
IUUC-Aly-005761	Arabidopsis lyrata	30.97	4.00e-40	158.00
IUUC-Ath-007476	Arabidopsis thaliana	31.27	2.00e-40	160.00
IUUC-Ame-011221	Astyanax mexicanus	66.86	3.00e-148	518.00
IUUC-Bta-013186	Bos taurus	91.48	0.00e+00	753.00
IUUC-Bdi-014298	Brachypodium distachyon	30.26	3.00e-39	155.00
IUUC-Bol-015192	Brassica oleracea	29.48	7.00e-39	154.00
IUUC-Bra-017078	Brassica rapa	30.03	7.00e-40	157.00
IUUC-Cel-018602	Caenorhabditis elegans	31.44	2.00e-56	213.00
IUUC-Cja-018909	Callithrix jacchus	88.14	0.00e+00	717.00
IUUC-Cfa-020970	Canis familiaris	91.26	0.00e+00	764.00
IUUC-Cpo-022215	Cavia porcellus	85.65	0.00e+00	685.00
IUUC-Csa-023530	Chlorocebus sabaeus	87.47	0.00e+00	735.00
IUUC-Cho-024598	Choloepus hoffmanni	93.55	9.00e-140	489.00
IUUC-Cin-025486	Ciona intestinalis	50.27	2.00e-104	372.00
IUUC-Csv-025930	Ciona savignyi	48.58	9.00e-94	337.00
IUUC-Dre-027507	Danio rerio	67.14	4.00e-149	520.00
IUUC-Dno-029726	Dasypus novemcinctus	89.47	0.00e+00	748.00
IUUC-Dor-030501	Dipodomys ordii	77.80	1.00e-177	615.00
IUUC-Ete-032794	Echinops telfairi	90.51	3.00e-139	487.00
IUUC-Eca-033982	Equus caballus	90.58	0.00e+00	710.00
IUUC-Eeu-035090	Erinaceus europaeus	90.33	2.00e-138	485.00
IUUC-Fca-035944	Felis catus	91.63	0.00e+00	775.00
IUUC-Fal-036992	Ficedula albicollis	65.62	6.00e-150	523.00
IUUC-Gmo-038710	Gadus morhua	64.90	2.00e-145	509.00
IUUC-Gga-040885	Gallus gallus	71.71	4.00e-112	397.00
IUUC-Gac-041922	Gasterosteus aculeatus	65.05	2.00e-149	521.00
IUUC-Gma-044233	Glycine max	30.77	7.00e-39	154.00
IUUC-Ggo-045172	Gorilla gorilla	89.11	0.00e+00	712.00
IUUC-Hsa-045711	Homo sapiens	87.92	0.00e+00	735.00
IUUC-Itr-048196	Ictidomys tridecemlineatus	89.46	0.00e+00	735.00
IUUC-Lch-049739	Latimeria chalumnae	73.20	3.00e-162	564.00
IUUC-Lpe-050795	Leersia perrieri	25.94	8.00e-23	101.00
IUUC-Loc-052113	Lepisosteus oculatus	74.14	2.00e-155	541.00
IUUC-Mcc-055022	Macaca mulatta	88.18	0.00e+00	731.00
IUUC-Meu-056003	Macropus eugenii	73.44	7.00e-164	569.00
IUUC-Mtr-058500	Medicago truncatula	29.70	5.00e-37	148.00
IUUC-Mga-059278	Meleagris gallopavo	70.65	4.00e-123	434.00
IUUC-Mmr-061148	Microcebus murinus	90.36	0.00e+00	748.00
IUUC-Mdo-063002	Monodelphis domestica	70.22	5.00e-161	560.00
IUUC-Mmu-063607	Mus musculus	87.00	0.00e+00	707.00
IUUC-Mac-065359	Musa acuminata	27.83	1.00e-36	147.00
IUUC-Mpu-066323	Mustela putorius furo	91.82	6.00e-178	616.00
IUUC-Mlu-067946	Myotis lucifugus	91.93	0.00e+00	779.00
IUUC-Nle-069019	Nomascus leucogenys	87.92	0.00e+00	731.00
IUUC-Opr-071047	Ochotona princeps	87.89	0.00e+00	726.00
IUUC-Ont-071694	Oreochromis niloticus	68.07	1.00e-151	528.00
IUUC-Oan-073474	Ornithorhynchus anatinus	55.85	6.00e-101	360.00
IUUC-Ocu-074493	Oryctolagus cuniculus	88.34	0.00e+00	713.00
IUUC-Oba-075468	Oryza barthii	27.54	1.00e-33	137.00
IUUC-Obr-076681	Oryza brachyantha	27.68	4.00e-35	142.00
IUUC-Ogl-077870	Oryza glaberrima	27.54	1.00e-33	137.00
IUUC-Ogu-078536	Oryza glumaepatula	27.54	1.00e-33	137.00
IUUC-Oin-080175	Oryza indica	27.54	1.00e-33	137.00
IUUC-Olo-080796	Oryza longistaminata	28.13	2.00e-32	133.00
IUUC-Oni-082076	Oryza nivara	27.54	1.00e-33	137.00
IUUC-Opu-083267	Oryza punctata	27.83	5.00e-34	138.00
IUUC-Oru-084553	Oryza rufipogon	27.56	4.00e-33	135.00
IUUC-Osa-085389	Oryza sativa	27.54	1.00e-33	137.00
IUUC-Ola-086414	Oryzias latipes	66.39	1.00e-148	519.00
IUUC-Oga-088656	Otolemur garnettii	88.79	0.00e+00	744.00
IUUC-Oar-089719	Ovis aries	91.07	0.00e+00	711.00
IUUC-Ptr-091087	Pan troglodytes	87.70	0.00e+00	732.00
IUUC-Pan-091709	Papio anubis	88.37	0.00e+00	744.00
IUUC-Psi-093265	Pelodiscus sinensis	70.90	4.00e-168	583.00
IUUC-Pma-094482	Petromyzon marinus	60.92	8.00e-60	222.00
IUUC-Ppa-095365	Physcomitrella patens	29.01	2.00e-38	152.00
IUUC-Pfo-097494	Poecilia formosa	66.67	2.00e-149	522.00
IUUC-Pab-098362	Pongo abelii	88.14	0.00e+00	736.00
IUUC-Pop-099163	Populus trichocarpa	30.12	3.00e-33	136.00
IUUC-Pca-101019	Procavia capensis	90.24	7.00e-158	550.00
IUUC-Ppe-102101	Prunus persica	29.25	2.00e-37	150.00
IUUC-Pva-102849	Pteropus vampyrus	92.38	0.00e+00	739.00
IUUC-Rno-105511	Rattus norvegicus	86.32	0.00e+00	702.00
IUUC-Sha-107265	Sarcophilus harrisii	69.06	8.00e-171	593.00
IUUC-Smo-108980	Selaginella moellendorffii	32.14	3.00e-35	142.00
IUUC-Sit-110806	Setaria italica	27.95	3.00e-35	142.00
IUUC-Sly-110994	Solanum lycopersicum	30.25	4.00e-37	149.00
IUUC-Stu-112493	Solanum tuberosum	34.74	2.00e-32	132.00
IUUC-Sar-113628	Sorex araneus	86.58	0.00e+00	696.00
IUUC-Sbi-114397	Sorghum bicolor	28.75	6.00e-36	144.00
IUUC-Ssc-116418	Sus scrofa	91.03	0.00e+00	770.00
IUUC-Tgu-117054	Taeniopygia guttata	69.83	3.00e-156	544.00
IUUC-Tru-118504	Takifugu rubripes	68.62	7.00e-159	553.00
IUUC-Tni-120254	Tetraodon nigroviridis	68.52	6.00e-158	550.00
IUUC-Tca-121085	Theobroma cacao	30.67	8.00e-38	150.00
IUUC-Tae-124320	Triticum aestivum	29.38	5.00e-38	152.00
IUUC-Tur-126756	Triticum urartu	27.20	2.00e-32	132.00
IUUC-Tbe-127903	Tupaia belangeri	83.86	0.00e+00	702.00
IUUC-Ttr-129118	Tursiops truncatus	89.71	0.00e+00	759.00
IUUC-Vvi-131125	Vitis vinifera	30.98	4.00e-38	152.00
IUUC-Xtr-132287	Xenopus tropicalis	74.50	4.00e-161	560.00
IUUC-Xma-134246	Xiphophorus maculatus	66.67	7.00e-149	520.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence