iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107376

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01180292

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000005142.1	ENSSHAT00000005950.1	ENSSHAP00000005896.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-64	219.0	24	432

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 44   epkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaee 132
            +   +  +lq+lf++l+ s+++a s+++l++++++ ++e  +++q+D+qE+ ++l+++le++l                         
   Q: 24   AKVRIIPLQLQRLFAQLLLSDQQAASTTDLTDSFGWNNSE--EMRQHDVQELNRILFSALESSL------------------------- 85
           34447889******************************98..**********************......................... PP
   S: 133  kkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekk 220
              +++++li++l++g++ ++i+c+ec+nvs+r+e+fldl+++v++ +      l+++L +++++ee ++ en y+c +c+k++ a+k+
   Q: 86   -VGTSGHDLINRLYHGTIVNHIMCKECENVSERQEDFLDLTVAVKNLT-----GLEEALwSMYVEEEFFDAENLYHCGTCDKLVCATKS 168
           .789******************************************99.....9*****999*************************** PP
   S: 221  lklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn........ 301
            +l+klP++L++ L Rf+f+ ++  r k + +++fpl++dl+pfc+++e +++ ++ Y+L++v++H+G++ +GHY++y+k+        
   Q: 169  ARLRKLPPFLTISLLRFNFDFAKRERYKETGSYTFPLQIDLKPFCEQSELDDS-EYLYDLFSVIIHKGGCYGGHYHVYIKDvdqlgnwq 256
           ***********************************************998875.9********************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 257  veedepeavaeatslkdlpsiqeadnplmvlkhilsqeenklipvdqlgqkllasidiswnkkyrkqhgsllkflqahsdvflvssnps 345
           ***************************************************************************************** PP
   S: 302  .................................................ekgk.WllfdDskVtevkeeevleetg..staYvlfYkr 337
                                                            e    W+ ++Ds+V++++e++++++ +  ++aY+lfY++
   Q: 346  kvclrrdagpaqsppaeldqtgpvapsqggdpevcgaesageqqvevsvEG-PhWFDINDSQVEPIQEADIEKQFQgkESAYMLFYRK 432
           **************************9999999999998877666665334.26*******************9889*********98 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

FAEALFALDP EELGLLEDKD DPNAKVRIIP LQLQRLFAQL LLSDQQAAST TDLTDSFGWN 60
NSEEMRQHDV QELNRILFSA LESSLVGTSG HDLINRLYHG TIVNHIMCKE CENVSERQED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTGCAGAAG CTTTGTTTGC CCTGGATCCA GAAGAGCTTG GATTGTTAGA GGACAAGGAT 60
GACCCCAATG CGAAGGTACC AGGGTCTCTT CTAGGTTCCC CAGTGGCTCC CAGGGAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	63.81	0.00e+00	1370.00
IUUC-Apl-004105	Anas platyrhynchos	61.96	0.00e+00	1446.00
IUUC-Aca-004715	Anolis carolinensis	58.49	0.00e+00	1328.00
IUUC-Ame-011073	Astyanax mexicanus	46.20	0.00e+00	967.00
IUUC-Bta-012487	Bos taurus	65.19	0.00e+00	1459.00
IUUC-Cja-018937	Callithrix jacchus	64.10	0.00e+00	1473.00
IUUC-Cfa-020645	Canis familiaris	59.35	0.00e+00	903.00
IUUC-Cpo-022160	Cavia porcellus	63.01	0.00e+00	1437.00
IUUC-Csa-023078	Chlorocebus sabaeus	65.00	0.00e+00	1511.00
IUUC-Cho-025013	Choloepus hoffmanni	51.95	1.00e-175	610.00
IUUC-Csv-026193	Ciona savignyi	57.99	7.00e-41	160.00
IUUC-Dre-027416	Danio rerio	49.63	0.00e+00	1086.00
IUUC-Dno-029639	Dasypus novemcinctus	61.60	0.00e+00	1259.00
IUUC-Dor-030624	Dipodomys ordii	77.30	3.00e-130	459.00
IUUC-Ete-032626	Echinops telfairi	54.35	0.00e+00	632.00
IUUC-Eca-034208	Equus caballus	64.75	0.00e+00	1479.00
IUUC-Eeu-035340	Erinaceus europaeus	48.55	7.00e-35	142.00
IUUC-Fca-035886	Felis catus	59.74	1.00e-176	612.00
IUUC-Fal-036925	Ficedula albicollis	60.80	0.00e+00	1331.00
IUUC-Gmo-038597	Gadus morhua	40.97	0.00e+00	777.00
IUUC-Gga-041171	Gallus gallus	61.54	0.00e+00	1422.00
IUUC-Gac-041362	Gasterosteus aculeatus	53.88	0.00e+00	635.00
IUUC-Ggo-045069	Gorilla gorilla	63.13	0.00e+00	1416.00
IUUC-Hsa-046715	Homo sapiens	64.27	0.00e+00	1465.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	61.88	0.00e+00	1368.00
IUUC-Lch-050182	Latimeria chalumnae	49.79	0.00e+00	1068.00
IUUC-Loc-052705	Lepisosteus oculatus	53.08	0.00e+00	1189.00
IUUC-Laf-054132	Loxodonta africana	64.35	0.00e+00	1495.00
IUUC-Mcc-055734	Macaca mulatta	64.72	0.00e+00	1497.00
IUUC-Meu-056135	Macropus eugenii	72.33	1.00e-143	504.00
IUUC-Mga-060092	Meleagris gallopavo	60.79	0.00e+00	1394.00
IUUC-Mmr-061546	Microcebus murinus	64.41	0.00e+00	1461.00
IUUC-Mdo-061935	Monodelphis domestica	78.65	0.00e+00	1870.00
IUUC-Mmu-063630	Mus musculus	62.09	0.00e+00	1428.00
IUUC-Mpu-066579	Mustela putorius furo	63.21	0.00e+00	1502.00
IUUC-Mlu-068034	Myotis lucifugus	63.90	0.00e+00	1455.00
IUUC-Nle-069082	Nomascus leucogenys	61.42	0.00e+00	1257.00
IUUC-Opr-070953	Ochotona princeps	54.13	0.00e+00	724.00
IUUC-Ont-072435	Oreochromis niloticus	46.49	0.00e+00	1043.00
IUUC-Oan-073339	Ornithorhynchus anatinus	64.27	0.00e+00	1454.00
IUUC-Ocu-073760	Oryctolagus cuniculus	63.01	0.00e+00	1459.00
IUUC-Ola-087015	Oryzias latipes	45.49	0.00e+00	872.00
IUUC-Oga-088960	Otolemur garnettii	64.27	0.00e+00	1474.00
IUUC-Oar-089853	Ovis aries	65.41	0.00e+00	1479.00
IUUC-Ptr-091093	Pan troglodytes	64.35	0.00e+00	1471.00
IUUC-Pan-091962	Papio anubis	64.08	0.00e+00	1488.00
IUUC-Psi-093691	Pelodiscus sinensis	62.88	0.00e+00	1471.00
IUUC-Pma-094428	Petromyzon marinus	66.98	3.00e-71	261.00
IUUC-Pfo-096983	Poecilia formosa	46.62	0.00e+00	960.00
IUUC-Pab-097860	Pongo abelii	63.87	0.00e+00	1442.00
IUUC-Pca-100514	Procavia capensis	55.89	1.00e-150	527.00
IUUC-Pva-102771	Pteropus vampyrus	63.03	0.00e+00	1428.00
IUUC-Rno-105405	Rattus norvegicus	61.76	0.00e+00	1418.00
IUUC-Ssc-115819	Sus scrofa	58.70	0.00e+00	1023.00
IUUC-Tgu-117262	Taeniopygia guttata	59.90	0.00e+00	1387.00
IUUC-Tru-117601	Takifugu rubripes	47.40	0.00e+00	1034.00
IUUC-Tsy-118996	Tarsius syrichta	56.34	0.00e+00	1194.00
IUUC-Tni-120682	Tetraodon nigroviridis	42.61	0.00e+00	810.00
IUUC-Tbe-127616	Tupaia belangeri	49.78	0.00e+00	929.00
IUUC-Ttr-129075	Tursiops truncatus	62.29	0.00e+00	1437.00
IUUC-Vpa-130108	Vicugna pacos	65.04	0.00e+00	1376.00
IUUC-Xtr-132623	Xenopus tropicalis	50.90	0.00e+00	1101.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence