iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107040

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01182309

Gene Name

TRIM65

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000001619.1	ENSSHAT00000001838.1	ENSSHAP00000001817.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.00e-07	29.2	8	57
E3 activity/RING/RING	3.60e-07	30.8	12	51

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqpltee 53
           e +lC+I lel r+ v+lp+G+ + r++I  + + ++  cP +r+p++++
   Q: 8    EKLLCAICLELYREAVTLPCGHNFCRACIINYWNLQEVDCPQCRTPFAQR 57
           6799******************************************9654 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           CaiCle +++  ++lpCgH f++ C+ + w        +e  CP Cr
   Q: 12   CAICLELYRE-AVTLPCGHNFCRACIiNYW------NLQEVDCPQCR 51
           ********88.999***********98999......888899****8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MATLPLEEKL LCAICLELYR EAVTLPCGHN FCRACIINYW NLQEVDCPQC RTPFAQRPEL 60
HKNGALCDVV ETLRAEGAAP EPGPGPTSAA RCPRHGWTLE LYCRTEKQCI CCACTVDQCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTACCC TGCCTCTAGA GGAGAAGCTG CTCTGTGCAA TCTGCCTGGA GCTGTACCGG 60
GAGGCGGTCA CTCTGCCCTG CGGCCATAAC TTCTGCCGGG CGTGCATAAT AAACTACTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010508--P:positive regulation of autophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002422	Ailuropoda melanoleuca	51.52	1.00e-98	353.00
IUUC-Apl-003984	Anas platyrhynchos	40.71	3.00e-14	70.50
IUUC-Ame-011110	Astyanax mexicanus	31.69	4.00e-52	198.00
IUUC-Bta-012830	Bos taurus	50.77	2.00e-113	402.00
IUUC-Cja-019398	Callithrix jacchus	61.76	5.00e-70	257.00
IUUC-Cfa-021033	Canis familiaris	51.05	1.00e-96	346.00
IUUC-Cpo-021359	Cavia porcellus	50.19	1.00e-115	410.00
IUUC-Csa-023706	Chlorocebus sabaeus	49.33	2.00e-118	419.00
IUUC-Dre-027965	Danio rerio	30.64	2.00e-56	213.00
IUUC-Dor-030830	Dipodomys ordii	49.41	9.00e-101	360.00
IUUC-Eca-033217	Equus caballus	51.16	5.00e-80	291.00
IUUC-Fca-036403	Felis catus	49.91	2.00e-119	422.00
IUUC-Fal-037118	Ficedula albicollis	42.55	2.00e-99	356.00
IUUC-Gmo-039107	Gadus morhua	31.02	4.00e-60	225.00
IUUC-Gac-042501	Gasterosteus aculeatus	29.45	2.00e-58	219.00
IUUC-Ggo-044481	Gorilla gorilla	49.04	3.00e-114	405.00
IUUC-Hsa-046113	Homo sapiens	50.67	3.00e-121	428.00
IUUC-Itr-049000	Ictidomys tridecemlineatus	46.05	2.00e-96	346.00
IUUC-Loc-052279	Lepisosteus oculatus	31.54	4.00e-63	235.00
IUUC-Laf-054143	Loxodonta africana	50.77	9.00e-115	406.00
IUUC-Mcc-055216	Macaca mulatta	49.13	1.00e-118	420.00
IUUC-Meu-056384	Macropus eugenii	83.65	2.00e-103	369.00
IUUC-Mmr-061758	Microcebus murinus	53.25	2.00e-120	426.00
IUUC-Mdo-062422	Monodelphis domestica	63.54	4.00e-122	431.00
IUUC-Mmu-063753	Mus musculus	46.78	2.00e-109	389.00
IUUC-Mpu-065880	Mustela putorius furo	50.29	3.00e-109	388.00
IUUC-Mlu-067629	Myotis lucifugus	48.23	2.00e-50	192.00
IUUC-Nle-069604	Nomascus leucogenys	51.39	6.00e-80	290.00
IUUC-Opr-070884	Ochotona princeps	50.00	4.00e-125	441.00
IUUC-Ont-072089	Oreochromis niloticus	31.03	2.00e-53	203.00
IUUC-Oan-073697	Ornithorhynchus anatinus	56.25	3.00e-49	187.00
IUUC-Ocu-073936	Oryctolagus cuniculus	43.77	1.00e-99	356.00
IUUC-Ola-086533	Oryzias latipes	25.92	3.00e-45	176.00
IUUC-Oga-087916	Otolemur garnettii	47.84	2.00e-87	315.00
IUUC-Oar-090188	Ovis aries	50.38	7.00e-100	357.00
IUUC-Ptr-091364	Pan troglodytes	52.56	9.00e-84	303.00
IUUC-Pan-092240	Papio anubis	50.39	3.00e-125	441.00
IUUC-Psi-093439	Pelodiscus sinensis	41.53	7.00e-49	186.00
IUUC-Pfo-097460	Poecilia formosa	30.53	1.00e-58	220.00
IUUC-Pab-098661	Pongo abelii	44.72	2.00e-97	348.00
IUUC-Pva-102208	Pteropus vampyrus	50.97	3.00e-120	425.00
IUUC-Rno-105456	Rattus norvegicus	46.56	3.00e-105	375.00
IUUC-Sar-113700	Sorex araneus	60.67	8.00e-61	227.00
IUUC-Ssc-115895	Sus scrofa	50.67	5.00e-122	431.00
IUUC-Tru-118244	Takifugu rubripes	29.64	3.00e-49	189.00
IUUC-Tni-120643	Tetraodon nigroviridis	30.53	8.00e-52	197.00
IUUC-Tbe-127865	Tupaia belangeri	51.69	1.00e-50	192.00
IUUC-Ttr-128578	Tursiops truncatus	51.34	1.00e-114	406.00
IUUC-Xtr-131897	Xenopus tropicalis	36.72	9.00e-86	310.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence