iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020573

Ensembl Protein ID

ENSCAFP00000000516.3

UniProt Accession

F1P6L5; F1P6L5_CANLF

Genbank Protein ID

ENSCAFP00000000516

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03007679

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000000360.3	ENSCAFT00000000567.3	ENSCAFP00000000516.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	84.66	7.00e-135	478.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	84.66	7.00e-135	478.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	81.82	8.00e-135	477.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	81.82	6.00e-133	471.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAMSYVKDDI FRIYIKEKKE CRRDHRPPCA QEAPRGLVHP NVICDGCNGP VVGTRYKCSV 60
CPDYDLCAAC EGKGLHREHS KLVFPGTFGP FSEGFSHSRW LRKLKHGHFG WPGWEMGPPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGGGGCGGC TATCCGGTGG ACGTCGGTGC AGGCGAAGTG GCGGGGGCGG GGCGCTTGGC 60
GCCGCCCCTC CCCCACCCCG CCGTGACGTC GCAGGTCCCG GCGACCTCGC GCTCCAGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR033741--SQSTM_UBA
IPR000433--Znf_ZZ

PROSITE

PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF16577--UBA_5
PF00569--ZZ

SMART

SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0042802--F:identical protein binding
GO:0043130--F:ubiquitin binding
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016239--P:positive regulation of macroautophagy
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	90.24	1.00e-152	532.00
IUUC-Apl-003897	Anas platyrhynchos	53.01	3.00e-90	325.00
IUUC-Aca-004699	Anolis carolinensis	43.03	8.00e-59	221.00
IUUC-Ame-010982	Astyanax mexicanus	36.71	4.00e-24	106.00
IUUC-Bta-012634	Bos taurus	83.19	6.00e-154	536.00
IUUC-Cel-018660	Caenorhabditis elegans	45.45	5.00e-11	60.50
IUUC-Cja-019684	Callithrix jacchus	82.01	3.00e-145	508.00
IUUC-Cpo-021425	Cavia porcellus	74.27	5.00e-123	434.00
IUUC-Csa-023968	Chlorocebus sabaeus	82.60	2.00e-141	495.00
IUUC-Cho-024596	Choloepus hoffmanni	79.49	1.00e-47	183.00
IUUC-Cne-027045	Cryptococcus neoformans	50.98	6.00e-10	60.10
IUUC-Dre-028621	Danio rerio	38.52	2.00e-56	213.00
IUUC-Dno-029060	Dasypus novemcinctus	81.92	4.00e-153	534.00
IUUC-Dor-030547	Dipodomys ordii	90.37	1.00e-101	363.00
IUUC-Ete-033201	Echinops telfairi	72.30	3.00e-128	451.00
IUUC-Eca-033456	Equus caballus	84.64	3.00e-160	557.00
IUUC-Eeu-035157	Erinaceus europaeus	79.24	1.00e-139	489.00
IUUC-Fca-035403	Felis catus	88.17	1.00e-154	539.00
IUUC-Fal-036798	Ficedula albicollis	52.21	1.00e-89	323.00
IUUC-Gmo-039619	Gadus morhua	43.09	1.00e-34	139.00
IUUC-Gga-040137	Gallus gallus	52.76	4.00e-89	322.00
IUUC-Gac-042410	Gasterosteus aculeatus	41.21	9.00e-59	220.00
IUUC-Ggo-044690	Gorilla gorilla	80.53	3.00e-141	494.00
IUUC-Hsa-046390	Homo sapiens	80.53	3.00e-141	494.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	85.84	7.00e-161	560.00
IUUC-Lch-049658	Latimeria chalumnae	42.65	8.00e-73	267.00
IUUC-Loc-052589	Lepisosteus oculatus	43.13	3.00e-71	262.00
IUUC-Laf-053746	Loxodonta africana	71.85	1.00e-120	426.00
IUUC-Mcc-055635	Macaca mulatta	82.89	3.00e-142	498.00
IUUC-Meu-056528	Macropus eugenii	43.27	6.00e-64	237.00
IUUC-Mga-059458	Meleagris gallopavo	53.31	1.00e-89	323.00
IUUC-Mvi-060347	Microbotryum violaceum	51.16	1.00e-07	52.80
IUUC-Mmr-061539	Microcebus murinus	80.67	1.00e-97	349.00
IUUC-Mdo-063083	Monodelphis domestica	58.53	4.00e-98	351.00
IUUC-Mmu-063589	Mus musculus	80.65	3.00e-149	521.00
IUUC-Mpu-065727	Mustela putorius furo	86.47	3.00e-160	557.00
IUUC-Mlu-067026	Myotis lucifugus	80.99	6.00e-149	520.00
IUUC-Nle-069356	Nomascus leucogenys	51.19	2.00e-60	226.00
IUUC-Opr-071091	Ochotona princeps	66.84	4.00e-75	275.00
IUUC-Ont-071864	Oreochromis niloticus	42.06	7.00e-65	241.00
IUUC-Oan-073308	Ornithorhynchus anatinus	58.99	2.00e-95	342.00
IUUC-Ocu-074110	Oryctolagus cuniculus	78.65	3.00e-146	511.00
IUUC-Ola-086944	Oryzias latipes	38.24	9.00e-22	96.30
IUUC-Oga-088869	Otolemur garnettii	77.19	3.00e-145	508.00
IUUC-Oar-089857	Ovis aries	83.04	1.00e-152	533.00
IUUC-Ptr-091640	Pan troglodytes	80.53	2.00e-141	494.00
IUUC-Pan-092831	Papio anubis	83.63	2.00e-141	495.00
IUUC-Psi-093925	Pelodiscus sinensis	54.86	5.00e-87	314.00
IUUC-Pma-094576	Petromyzon marinus	37.58	2.00e-17	83.60
IUUC-Pfo-097297	Poecilia formosa	41.28	5.00e-57	215.00
IUUC-Pab-098725	Pongo abelii	74.49	2.00e-123	436.00
IUUC-Pca-101106	Procavia capensis	82.40	1.00e-136	479.00
IUUC-Pva-102710	Pteropus vampyrus	85.62	6.00e-143	500.00
IUUC-Rno-105539	Rattus norvegicus	81.82	2.00e-152	531.00
IUUC-Sha-107469	Sarcophilus harrisii	52.39	2.00e-95	342.00
IUUC-Ssc-115526	Sus scrofa	84.96	2.00e-148	518.00
IUUC-Tgu-117194	Taeniopygia guttata	55.29	9.00e-90	323.00
IUUC-Tru-117896	Takifugu rubripes	44.48	2.00e-62	233.00
IUUC-Tni-119943	Tetraodon nigroviridis	43.06	2.00e-53	202.00
IUUC-Ttr-128676	Tursiops truncatus	84.37	2.00e-158	551.00
IUUC-Vda-129812	Verticillium dahliae	36.36	1.00e-07	51.60
IUUC-Vpa-130319	Vicugna pacos	94.12	5.00e-48	184.00
IUUC-Xtr-132907	Xenopus tropicalis	50.14	4.00e-88	318.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence