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Tag Content
iUUCD ID IUUC-Afu-008791
Ensembl Protein ID CADAFUAP00008303
UniProt Accession Q4WNK7; SEC13_ASPFU
Genbank Protein ID EAL90177.1
Protein Name Protein transport protein sec13
Genbank Nucleotide ID AAHF01000005
Gene Name AFUA_4G06090; sec13
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
CADAFUAG00008303 CADAFUAT00008303 CADAFUAP00008303
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.90e-33 111.5 52 84
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWD 29
    gH++ v+c+a+ + t+l+s+s+Dg++ +W+
   Q: 52 GHEGAVWCVAWahPKfgTILASSSYDGKVLIWR 84
    8***********9555599*************8 PP
   

Organism Aspergillus fumigatus
Functional Description
(View)

Functional Description



     Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Protein Sequence
(Fasta)
MTRGTNLVGP FLQHDAGLDY YGRRLATCSS DKTIKIFEIE GETHRLIETL KGHEGAVWCV 60
AWAHPKFGTI LASSSYDGKV LIWREQHQNA TSPVAGSTWT KVFDFSLHTA SVNMVSWAPH 120
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Protein Fasta Sequence



>IUUC-Afu-008791|E3,WD_repeat|Aspergillus fumigatus
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Nucleotide Sequence
(Fasta)
ATGACCCGCG GGACTAACTT GGTCGGCCCT TTCTTGCAGC ACGACGCCGG ACTGGACTAC 60
TATGGTCGCA GATTAGCAAC ATGTTCGTCG GACAAGACAA TAAAGATTTT CGAAATCGAG 120
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Nucleotide Fasta Sequence



>IUUC-Afu-008791|E3,WD_repeat|Aspergillus fumigatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030127--C:COPII vesicle coat
GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0031080--C:nuclear pore outer ring
GO:0035859--C:Seh1-associated complex
GO:0005198--F:structural molecule activity
GO:0090114--P:COPII-coated vesicle budding
GO:0051028--P:mRNA transport
GO:0031081--P:nuclear pore distribution
GO:0043547--P:positive regulation of GTPase activity
GO:1904263--P:positive regulation of TORC1 signaling
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0015031--P:protein transport
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG afm:AFUA_4G06090
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000671 Aegilops tauschii 50.33 6.00e-77 278.00
IUUC-Aml-001832 Ailuropoda melanoleuca 50.83 3.00e-80 290.00
IUUC-Atr-002914 Amborella trichopoda 50.34 6.00e-77 278.00
IUUC-Apl-003992 Anas platyrhynchos 51.84 1.00e-81 294.00
IUUC-Aca-005283 Anolis carolinensis 51.16 3.00e-81 293.00
IUUC-Aly-005654 Arabidopsis lyrata 48.34 5.00e-71 259.00
IUUC-Ath-006816 Arabidopsis thaliana 48.51 2.00e-70 256.00
IUUC-Ago-007827 Ashbya gossypii 57.10 4.00e-95 339.00
IUUC-Acl-008205 Aspergillus clavatus 96.61 1.00e-170 590.00
IUUC-Afl-008748 Aspergillus flavus 95.25 4.00e-169 585.00
IUUC-Ani-009152 Aspergillus nidulans 90.85 1.00e-163 566.00
IUUC-Ang-009765 Aspergillus niger 96.95 1.00e-171 593.00
IUUC-Aor-009927 Aspergillus oryzae 95.90 6.00e-169 584.00
IUUC-Ate-010248 Aspergillus terreus 95.25 4.00e-170 588.00
IUUC-Ame-011478 Astyanax mexicanus 51.16 4.00e-82 296.00
IUUC-Bgr-012276 Blumeria graminis 70.41 6.00e-123 431.00
IUUC-Bta-012700 Bos taurus 50.17 2.00e-79 286.00
IUUC-Bci-013722 Botrytis cinerea 70.57 7.00e-124 434.00
IUUC-Bdi-014818 Brachypodium distachyon 50.33 1.00e-76 277.00
IUUC-Bol-015779 Brassica oleracea 48.36 3.00e-70 256.00
IUUC-Bra-017934 Brassica rapa 48.68 2.00e-70 257.00
IUUC-Cel-018479 Caenorhabditis elegans 38.98 2.00e-57 213.00
IUUC-Cja-019956 Callithrix jacchus 51.41 6.00e-74 269.00
IUUC-Cfa-020752 Canis familiaris 50.83 4.00e-80 289.00
IUUC-Cpo-021871 Cavia porcellus 51.50 4.00e-81 293.00
IUUC-Cre-022797 Chlamydomonas reinhardtii 48.32 2.00e-74 270.00
IUUC-Csa-023393 Chlorocebus sabaeus 51.50 1.00e-80 291.00
IUUC-Cho-024786 Choloepus hoffmanni 58.00 2.00e-26 111.00
IUUC-Cin-025332 Ciona intestinalis 53.14 4.00e-84 302.00
IUUC-Csv-025926 Ciona savignyi 53.16 1.00e-83 301.00
IUUC-Cgl-026413 Colletotrichum gloeosporioides 71.14 1.00e-116 410.00
IUUC-Cne-027054 Cryptococcus neoformans 50.48 5.00e-76 275.00
IUUC-Cme-027165 Cyanidioschyzon merolae 36.66 6.00e-49 187.00
IUUC-Dre-027782 Danio rerio 51.83 4.00e-82 296.00
IUUC-Dno-029628 Dasypus novemcinctus 50.50 7.00e-80 288.00
IUUC-Dor-030650 Dipodomys ordii 49.14 8.00e-58 215.00
IUUC-Dse-031206 Dothistroma septosporum 66.23 1.00e-113 400.00
IUUC-Dme-031854 Drosophila melanogaster 50.00 7.00e-72 262.00
IUUC-Ete-032618 Echinops telfairi 42.86 1.00e-36 145.00
IUUC-Eca-033268 Equus caballus 50.83 5.00e-80 288.00
IUUC-Fca-035918 Felis catus 50.83 8.00e-80 288.00
IUUC-Fal-037551 Ficedula albicollis 51.16 2.00e-76 277.00
IUUC-Fox-037763 Fusarium oxysporum 71.57 3.00e-125 439.00
IUUC-Fso-038341 Fusarium solani 71.67 3.00e-126 442.00
IUUC-Gmo-038638 Gadus morhua 50.17 1.00e-80 291.00
IUUC-Ggr-039865 Gaeumannomyces graminis 70.57 1.00e-122 430.00
IUUC-Gga-040193 Gallus gallus 51.50 1.00e-81 294.00
IUUC-Gac-041337 Gasterosteus aculeatus 33.22 2.00e-32 131.00
IUUC-Gma-044311 Glycine max 50.00 5.00e-75 273.00
IUUC-Ggo-045252 Gorilla gorilla 51.50 1.00e-80 291.00
IUUC-Hsa-046565 Homo sapiens 51.50 1.00e-80 291.00
IUUC-Hvu-047835 Hordeum vulgare 51.00 5.00e-77 279.00
IUUC-Itr-048587 Ictidomys tridecemlineatus 51.16 2.00e-80 290.00
IUUC-Kpa-049148 Komagataella pastoris 58.86 6.00e-96 342.00
IUUC-Lch-050421 Latimeria chalumnae 52.49 1.00e-83 301.00
IUUC-Lpe-051187 Leersia perrieri 48.49 3.00e-76 279.00
IUUC-Loc-052167 Lepisosteus oculatus 50.83 4.00e-83 299.00
IUUC-Lma-053250 Leptosphaeria maculans 69.26 9.00e-118 414.00
IUUC-Laf-054304 Loxodonta africana 50.83 1.00e-80 291.00
IUUC-Mcc-055519 Macaca mulatta 51.50 1.00e-80 291.00
IUUC-Meu-056439 Macropus eugenii 50.83 3.00e-81 293.00
IUUC-Mor-057241 Magnaporthe oryzae 71.48 4.00e-125 438.00
IUUC-Mpo-057373 Magnaporthe poae 62.50 9.00e-101 357.00
IUUC-Mtr-058412 Medicago truncatula 48.99 1.00e-73 267.00
IUUC-Mla-058966 Melampsora laricipopulina 50.15 1.00e-87 314.00
IUUC-Mga-060066 Meleagris gallopavo 51.84 1.00e-81 294.00
IUUC-Mvi-060290 Microbotryum violaceum 53.27 1.00e-86 314.00
IUUC-Mmr-060717 Microcebus murinus 51.16 1.00e-80 291.00
IUUC-Mdo-062496 Monodelphis domestica 50.50 5.00e-81 292.00
IUUC-Mmu-063490 Mus musculus 51.16 2.00e-80 290.00
IUUC-Mac-064519 Musa acuminata 48.99 3.00e-73 266.00
IUUC-Mpu-066601 Mustela putorius furo 50.83 4.00e-80 289.00
IUUC-Mlu-067501 Myotis lucifugus 50.83 3.00e-80 290.00
IUUC-Nfi-068360 Neosartorya fischeri 98.08 1.00e-149 520.00
IUUC-Ncr-068928 Neurospora crassa 70.29 4.00e-129 452.00
IUUC-Nle-069028 Nomascus leucogenys 51.16 1.00e-80 291.00
IUUC-Opr-070446 Ochotona princeps 50.84 1.00e-79 287.00
IUUC-Ont-071587 Oreochromis niloticus 52.16 2.00e-83 300.00
IUUC-Oan-073211 Ornithorhynchus anatinus 49.83 6.00e-80 288.00
IUUC-Ocu-074306 Oryctolagus cuniculus 51.16 5.00e-81 292.00
IUUC-Oba-075069 Oryza barthii 50.00 1.00e-75 274.00
IUUC-Obr-076667 Oryza brachyantha 50.67 1.00e-76 277.00
IUUC-Ogl-077208 Oryza glaberrima 50.00 1.00e-75 274.00
IUUC-Ogu-078513 Oryza glumaepatula 50.00 1.00e-75 274.00
IUUC-Oin-079094 Oryza indica 50.00 1.00e-75 274.00
IUUC-Olo-080473 Oryza longistaminata 50.00 1.00e-75 274.00
IUUC-Ome-081643 Oryza meridionalis 50.00 1.00e-75 274.00
IUUC-Oni-082589 Oryza nivara 50.00 1.00e-75 274.00
IUUC-Opu-083677 Oryza punctata 50.00 1.00e-75 274.00
IUUC-Oru-084537 Oryza rufipogon 50.00 1.00e-75 274.00
IUUC-Osa-085449 Oryza sativa 50.00 1.00e-75 274.00
IUUC-Ola-087226 Oryzias latipes 51.50 1.00e-82 297.00
IUUC-Olu-087893 Ostreococcus lucimarinus 49.33 2.00e-67 247.00
IUUC-Oga-088837 Otolemur garnettii 50.83 4.00e-80 289.00
IUUC-Oar-089594 Ovis aries 50.50 2.00e-79 287.00
IUUC-Ptr-091132 Pan troglodytes 51.50 8.00e-81 291.00
IUUC-Pan-092013 Papio anubis 32.65 1.00e-25 108.00
IUUC-Psi-093568 Pelodiscus sinensis 51.16 1.00e-81 294.00
IUUC-Pma-094172 Petromyzon marinus 46.79 8.00e-33 130.00
IUUC-Pno-094955 Phaeosphaeria nodorum 68.58 1.00e-117 413.00
IUUC-Ppa-095835 Physcomitrella patens 50.51 2.00e-74 270.00
IUUC-Pfo-096063 Poecilia formosa 52.16 6.00e-83 298.00
IUUC-Pab-098674 Pongo abelii 51.16 9.00e-80 288.00
IUUC-Pop-099402 Populus trichocarpa 47.97 5.00e-72 262.00
IUUC-Pca-100824 Procavia capensis 38.33 8.00e-55 205.00
IUUC-Ppe-101707 Prunus persica 46.96 6.00e-71 259.00
IUUC-Pva-103161 Pteropus vampyrus 46.84 2.00e-72 263.00
IUUC-Pgr-103573 Puccinia graminis 50.95 8.00e-88 315.00
IUUC-Ptt-103700 Puccinia triticina 49.52 8.00e-85 305.00
IUUC-Pte-104267 Pyrenophora teres 67.00 8.00e-114 401.00
IUUC-Pyt-104535 Pyrenophora triticirepentis 65.99 6.00e-109 385.00
IUUC-Rno-104833 Rattus norvegicus 51.16 2.00e-80 290.00
IUUC-Sce-106437 Saccharomyces cerevisiae 60.20 1.00e-93 333.00
IUUC-Sha-106611 Sarcophilus harrisii 50.83 3.00e-81 293.00
IUUC-Sja-107654 Schizosaccharomyces japonicus 54.70 2.00e-88 317.00
IUUC-Spo-108362 Schizosaccharomyces pombe 54.05 4.00e-85 306.00
IUUC-Smo-108797 Selaginella moellendorffii 48.67 1.00e-73 268.00
IUUC-Sit-110132 Setaria italica 50.50 2.00e-76 277.00
IUUC-Sly-111254 Solanum lycopersicum 47.30 3.00e-70 256.00
IUUC-Stu-112195 Solanum tuberosum 48.32 3.00e-71 259.00
IUUC-Sar-113279 Sorex araneus 31.23 3.00e-24 104.00
IUUC-Sbi-114229 Sorghum bicolor 51.84 8.00e-78 281.00
IUUC-Sre-114898 Sporisorium reilianum 48.25 3.00e-82 296.00
IUUC-Ssc-115995 Sus scrofa 52.71 2.00e-36 143.00
IUUC-Tgu-116793 Taeniopygia guttata 50.83 3.00e-76 276.00
IUUC-Tru-117797 Takifugu rubripes 51.16 2.00e-82 296.00
IUUC-Tsy-118913 Tarsius syrichta 31.09 4.00e-22 97.10
IUUC-Tni-120366 Tetraodon nigroviridis 52.49 4.00e-84 302.00
IUUC-Tca-121068 Theobroma cacao 48.97 1.00e-72 265.00
IUUC-Tre-121899 Trichoderma reesei 70.57 6.00e-124 434.00
IUUC-Tvi-122380 Trichoderma virens 70.90 1.00e-124 436.00
IUUC-Tae-123998 Triticum aestivum 51.00 5.00e-78 282.00
IUUC-Tur-126202 Triticum urartu 50.67 4.00e-77 279.00
IUUC-Tme-127181 Tuber melanosporum 59.01 3.00e-105 373.00
IUUC-Ttr-128448 Tursiops truncatus 50.00 1.00e-64 238.00
IUUC-Uma-129661 Ustilago maydis 48.37 4.00e-83 299.00
IUUC-Vda-129666 Verticillium dahliae 71.14 5.00e-120 422.00
IUUC-Vpa-130318 Vicugna pacos 50.83 7.00e-80 288.00
IUUC-Vvi-130868 Vitis vinifera 49.66 4.00e-75 272.00
IUUC-Xtr-131859 Xenopus tropicalis 51.83 1.00e-82 298.00
IUUC-Xma-133898 Xiphophorus maculatus 52.49 2.00e-83 300.00
IUUC-Yli-134559 Yarrowia lipolytica 60.74 2.00e-97 347.00
Created Date 25-Jun-2017

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