iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002068

Ensembl Protein ID

ENSAMEP00000015358.1

UniProt Accession

G1M7N8; G1M7N8_AILME

Genbank Protein ID

ENSAMEP00000015358

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01156654

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000014579.1	ENSAMET00000015997.1	ENSAMEP00000015358.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.30e-10	41.1	538	575
ULD/UDP/UBQ/UBQ_PIM	1.80e-23	82.3	34	107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 538  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 575
           79***********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 34   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQN 107
           69**********.***********************************************************986 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAENGESSGG PPRPSRGPAS AQGPASAPAE PKIIKVTVKT PKEKEEFAVP ENSSVQQFKE 60
AISKRFKSQT DQLVLIFAGK ILKDQDTLIQ HGIHDGLTVH LVIKSQNRPQ GQSTQPSNAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ACGGCGAGAG TAGCGGCGGC CCCCCGCGCC CCTCCCGCGG CCCTGCTTCG 60
GCCCAAGGCC CTGCCTCTGC CCCGGCCGAG CCCAAAATCA TCAAAGTCAC TGTGAAGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afu-009029	Aspergillus fumigatus	33.75	4.00e-07	49.30
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	2.00e-11	63.20
IUUC-Dno-029647	Dasypus novemcinctus	93.93	1.00e-179	623.00
IUUC-Eeu-034727	Erinaceus europaeus	92.68	3.00e-168	585.00
IUUC-Ggo-044519	Gorilla gorilla	95.90	0.00e+00	702.00
IUUC-Itr-048556	Ictidomys tridecemlineatus	91.49	3.00e-167	582.00
IUUC-Mcc-054658	Macaca mulatta	92.08	0.00e+00	692.00
IUUC-Mor-057194	Magnaporthe oryzae	49.02	2.00e-07	50.40
IUUC-Nfi-068487	Neosartorya fischeri	33.75	2.00e-07	50.40
IUUC-Ocu-074520	Oryctolagus cuniculus	87.97	0.00e+00	719.00
IUUC-Pop-099214	Populus trichocarpa	35.25	2.00e-37	150.00
IUUC-Pca-100227	Procavia capensis	96.00	4.00e-88	318.00
IUUC-Tsy-119008	Tarsius syrichta	94.91	8.00e-167	580.00
IUUC-Vda-129991	Verticillium dahliae	46.15	4.00e-07	49.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence