iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066474

Ensembl Protein ID

ENSMPUP00000018511.1

UniProt Accession

M3Z4J9; M3Z4J9_MUSPF

Genbank Protein ID

ENSMPUP00000018511

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01107197

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000018630.1	ENSMPUT00000018782.1	ENSMPUP00000018511.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.70e-10	40.7	581	618
ULD/UDP/UBQ/UBQ_PIM	2.00e-23	82.2	33	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 581  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 618
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 33   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQN 106
           69**********.***********************************************************986 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAENGESSGP PRPSRGPAAA QGPASAPAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA 60
ISKRFKSQTD QLVLIFAGKI LKDQDTLIQH GIHDGLTVHL VIKSQNRPQG QSTQPSNAAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ACGGCGAGAG TAGCGGCCCC CCGCGCCCCT CCCGCGGCCC TGCTGCGGCC 60
CAAGGCCCTG CCTCTGCCCC GGCCGAGCCC AAAATCATCA AAGTCACTGT GAAGACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afu-009029	Aspergillus fumigatus	33.75	4.00e-07	49.70
IUUC-Bta-013571	Bos taurus	97.95	0.00e+00	632.00
IUUC-Cfa-020799	Canis familiaris	99.10	0.00e+00	640.00
IUUC-Cpo-022093	Cavia porcellus	90.74	3.00e-173	601.00
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	3.00e-11	62.80
IUUC-Csa-023627	Chlorocebus sabaeus	90.66	0.00e+00	733.00
IUUC-Cho-024552	Choloepus hoffmanni	91.91	1.00e-174	605.00
IUUC-Cne-026833	Cryptococcus neoformans	26.64	3.00e-13	69.70
IUUC-Dno-029647	Dasypus novemcinctus	94.06	0.00e+00	647.00
IUUC-Ete-033071	Echinops telfairi	88.16	0.00e+00	723.00
IUUC-Eeu-034727	Erinaceus europaeus	94.06	2.00e-175	608.00
IUUC-Fca-035803	Felis catus	99.10	0.00e+00	626.00
IUUC-Fso-038204	Fusarium solani	42.25	9.00e-09	54.70
IUUC-Hsa-046768	Homo sapiens	97.52	3.00e-177	614.00
IUUC-Itr-048556	Ictidomys tridecemlineatus	91.48	0.00e+00	631.00
IUUC-Mor-057194	Magnaporthe oryzae	49.02	1.00e-07	51.20
IUUC-Mmr-061605	Microcebus murinus	95.69	3.00e-172	598.00
IUUC-Mlu-067252	Myotis lucifugus	86.07	8.00e-171	593.00
IUUC-Nfi-068487	Neosartorya fischeri	33.75	2.00e-07	50.40
IUUC-Ncr-068732	Neurospora crassa	48.00	2.00e-07	50.40
IUUC-Nle-069038	Nomascus leucogenys	97.52	4.00e-178	617.00
IUUC-Oga-088005	Otolemur garnettii	97.07	3.00e-177	614.00
IUUC-Oar-089878	Ovis aries	97.74	0.00e+00	631.00
IUUC-Ptr-090781	Pan troglodytes	97.52	1.00e-177	616.00
IUUC-Pab-097891	Pongo abelii	97.74	1.00e-177	616.00
IUUC-Pca-100227	Procavia capensis	95.36	1.00e-94	340.00
IUUC-Tsy-119008	Tarsius syrichta	94.44	9.00e-166	577.00
IUUC-Vda-129991	Verticillium dahliae	46.15	3.00e-07	49.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence