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Tag Content
iUUCD ID IUUC-Fca-036467
Ensembl Protein ID ENSFCAP00000019449.1
UniProt Accession M3WYK9; M3WYK9_FELCA
Genbank Protein ID ENSFCAP00000019449
Protein Name Inhibitor of growth protein
Genbank Nucleotide ID AANG02062383
Gene Name ING2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000028949.1 ENSFCAT00000024827.1 ENSFCAP00000019449.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 5.50e-09 36.1 227 273
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
    ++C +C + + +e ++ C++ C ewfH+ C++l+ +p+ + w+CpkCr
   Q: 227 TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 273
    69*.*******99..*****999*99***********...888886.******8 PP
   

Organism Felis catus
Protein Sequence
(Fasta)
AAAAAAARSS SGGRMLGQQQ QQLYSSAALL TGERSRLLTC YVQDYLECVE SLPHDMQRNV 60
SVLRELDNKY QETLKEIDDV YEKYKKEDDS NQKKRLQQHL QRALINSQEL GDEKIQIVTQ 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Fca-036467|E3,PHD|Felis catus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGCGGCGG CGGCGGCGGC GAGGAGCAGC AGCGGCGGCA GGATGTTAGG GCAGCAGCAG 60
CAGCAACTAT ACTCGTCGGC CGCGCTCCTG ACCGGGGAGC GGAGCCGGCT CCTCACCTGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Fca-036467|E3,PHD|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002213 Ailuropoda melanoleuca 99.64 6.00e-124 436.00
IUUC-Apl-003705 Anas platyrhynchos 88.79 7.00e-92 329.00
IUUC-Aca-004990 Anolis carolinensis 81.08 6.00e-98 350.00
IUUC-Ame-011426 Astyanax mexicanus 70.80 4.00e-84 304.00
IUUC-Bta-012721 Bos taurus 98.53 7.00e-121 426.00
IUUC-Cja-018960 Callithrix jacchus 98.11 1.00e-106 379.00
IUUC-Cfa-020869 Canis familiaris 99.29 9.00e-125 439.00
IUUC-Cpo-021414 Cavia porcellus 97.14 1.00e-120 425.00
IUUC-Csa-023304 Chlorocebus sabaeus 98.21 5.00e-113 400.00
IUUC-Cne-027005 Cryptococcus neoformans 48.48 8.00e-16 77.80
IUUC-Dre-028562 Danio rerio 69.00 2.00e-89 322.00
IUUC-Dno-029945 Dasypus novemcinctus 98.11 5.00e-116 410.00
IUUC-Dor-030141 Dipodomys ordii 96.79 1.00e-118 419.00
IUUC-Ete-032709 Echinops telfairi 95.41 5.00e-128 450.00
IUUC-Eca-033432 Equus caballus 98.90 1.00e-120 425.00
IUUC-Eeu-035285 Erinaceus europaeus 98.54 3.00e-91 327.00
IUUC-Fal-036700 Ficedula albicollis 87.56 4.00e-91 327.00
IUUC-Gmo-038748 Gadus morhua 62.68 5.00e-85 307.00
IUUC-Gga-040175 Gallus gallus 88.34 1.00e-91 328.00
IUUC-Gac-041403 Gasterosteus aculeatus 64.23 7.00e-90 323.00
IUUC-Hsa-045837 Homo sapiens 98.21 5.00e-113 400.00
IUUC-Itr-049062 Ictidomys tridecemlineatus 98.57 5.00e-122 430.00
IUUC-Lch-049965 Latimeria chalumnae 80.53 5.00e-100 357.00
IUUC-Laf-053353 Loxodonta africana 96.44 1.00e-100 358.00
IUUC-Mcc-055155 Macaca mulatta 98.28 5.00e-73 266.00
IUUC-Meu-056470 Macropus eugenii 92.91 4.00e-111 394.00
IUUC-Mga-059570 Meleagris gallopavo 88.34 4.00e-91 327.00
IUUC-Mmr-061385 Microcebus murinus 98.57 1.00e-113 402.00
IUUC-Mdo-062144 Monodelphis domestica 92.97 2.00e-112 398.00
IUUC-Mmu-063215 Mus musculus 96.80 8.00e-120 422.00
IUUC-Mpu-065749 Mustela putorius furo 99.16 1.00e-101 362.00
IUUC-Nle-069968 Nomascus leucogenys 97.89 1.00e-81 295.00
IUUC-Ont-071524 Oreochromis niloticus 65.93 9.00e-87 313.00
IUUC-Ocu-074870 Oryctolagus cuniculus 99.26 2.00e-121 428.00
IUUC-Ola-087400 Oryzias latipes 89.02 2.00e-44 171.00
IUUC-Oga-088336 Otolemur garnettii 97.21 4.00e-114 404.00
IUUC-Oar-090136 Ovis aries 98.15 4.00e-119 420.00
IUUC-Ptr-091348 Pan troglodytes 98.42 2.00e-82 298.00
IUUC-Pan-092819 Papio anubis 98.21 5.00e-113 400.00
IUUC-Pma-094265 Petromyzon marinus 72.22 9.00e-32 129.00
IUUC-Pfo-096633 Poecilia formosa 63.79 8.00e-81 293.00
IUUC-Pab-098346 Pongo abelii 98.21 6.00e-113 399.00
IUUC-Pca-100278 Procavia capensis 95.67 4.00e-117 413.00
IUUC-Pva-103190 Pteropus vampyrus 99.24 4.00e-117 413.00
IUUC-Rno-104940 Rattus norvegicus 96.97 2.00e-114 405.00
IUUC-Sha-107533 Sarcophilus harrisii 91.18 2.00e-113 401.00
IUUC-Sar-113630 Sorex araneus 97.56 1.00e-91 328.00
IUUC-Ssc-115734 Sus scrofa 99.24 7.00e-117 413.00
IUUC-Tgu-117034 Taeniopygia guttata 88.00 1.00e-91 328.00
IUUC-Tru-118168 Takifugu rubripes 60.34 2.00e-81 295.00
IUUC-Tsy-119494 Tarsius syrichta 98.95 6.00e-83 299.00
IUUC-Tni-120100 Tetraodon nigroviridis 60.52 2.00e-77 281.00
IUUC-Ttr-128442 Tursiops truncatus 98.54 3.00e-91 327.00
IUUC-Vpa-130063 Vicugna pacos 98.57 2.00e-122 431.00
Created Date 25-Jun-2017

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