iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041403

Ensembl Protein ID

ENSGACP00000001097.1

UniProt Accession

G3N722; G3N722_GASAC

Protein Name

Inhibitor of growth protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000000852.1	ENSGACT00000001097.1	ENSGACP00000001097.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.00e-08	35.6	214	260

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 214  TYC-LCEQVSYGE--MIGCDNdqCPiEWFHFSCVGLT---YKPKGK-WYCPKCR 260
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MLGHHYPNAD KSQQLVNYVE DYLECVESLP LDIQRNVSLL REIDAKYQEV LKEVDEVFEK 60
YKSEQDAAQR KRLQIQLQRA LIISQELGDE KIHVVTQMTE LVENRSRQMD SHSICLQEPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTAGGCC ACCACTACCC AAATGCCGAC AAGTCGCAAC AACTGGTCAA CTATGTGGAG 60
GATTATCTGG AATGTGTGGA GTCCCTGCCT TTGGACATAC AAAGAAATGT TTCTCTGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	62.77	1.00e-77	283.00
IUUC-Aca-004990	Anolis carolinensis	63.30	3.00e-82	298.00
IUUC-Ame-011426	Astyanax mexicanus	68.20	8.00e-87	313.00
IUUC-Bta-012721	Bos taurus	62.04	9.00e-77	280.00
IUUC-Cja-018960	Callithrix jacchus	62.64	3.00e-70	258.00
IUUC-Cfa-020869	Canis familiaris	63.00	2.00e-77	282.00
IUUC-Cpo-021414	Cavia porcellus	62.41	4.00e-77	280.00
IUUC-Csa-023304	Chlorocebus sabaeus	62.64	3.00e-70	258.00
IUUC-Dre-028562	Danio rerio	69.40	6.00e-98	350.00
IUUC-Dno-029945	Dasypus novemcinctus	62.64	1.00e-76	279.00
IUUC-Dor-030141	Dipodomys ordii	61.54	3.00e-75	274.00
IUUC-Ete-032709	Echinops telfairi	61.68	2.00e-85	308.00
IUUC-Eca-033432	Equus caballus	62.41	5.00e-77	280.00
IUUC-Eeu-035285	Erinaceus europaeus	61.40	4.00e-61	227.00
IUUC-Fca-036467	Felis catus	62.64	5.00e-77	280.00
IUUC-Gmo-038748	Gadus morhua	78.52	1.00e-113	402.00
IUUC-Hsa-045837	Homo sapiens	62.64	3.00e-70	258.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	62.64	5.00e-77	280.00
IUUC-Meu-056470	Macropus eugenii	64.77	1.00e-83	302.00
IUUC-Mga-059570	Meleagris gallopavo	62.23	2.00e-68	251.00
IUUC-Mmr-061385	Microcebus murinus	62.64	3.00e-70	258.00
IUUC-Mdo-062144	Monodelphis domestica	64.77	8.00e-84	303.00
IUUC-Mmu-063215	Mus musculus	61.31	2.00e-76	278.00
IUUC-Mpu-065749	Mustela putorius furo	62.65	2.00e-68	251.00
IUUC-Ont-071524	Oreochromis niloticus	89.68	9.00e-133	466.00
IUUC-Ocu-074870	Oryctolagus cuniculus	62.64	4.00e-77	280.00
IUUC-Ola-087400	Oryzias latipes	82.83	3.00e-87	314.00
IUUC-Olu-087851	Ostreococcus lucimarinus	67.31	1.00e-18	86.30
IUUC-Oga-088336	Otolemur garnettii	62.64	3.00e-70	258.00
IUUC-Oar-090136	Ovis aries	61.68	2.00e-76	278.00
IUUC-Pan-092819	Papio anubis	62.64	3.00e-70	258.00
IUUC-Pfo-096633	Poecilia formosa	88.26	1.00e-122	432.00
IUUC-Pab-098346	Pongo abelii	62.64	6.00e-70	257.00
IUUC-Pca-100278	Procavia capensis	62.88	1.00e-82	299.00
IUUC-Pva-103190	Pteropus vampyrus	62.64	3.00e-77	281.00
IUUC-Rno-104940	Rattus norvegicus	61.68	3.00e-76	278.00
IUUC-Sha-107533	Sarcophilus harrisii	65.53	3.00e-84	304.00
IUUC-Sar-113630	Sorex araneus	62.33	5.00e-61	227.00
IUUC-Ssc-115734	Sus scrofa	62.64	3.00e-77	281.00
IUUC-Tru-118168	Takifugu rubripes	82.21	4.00e-114	404.00
IUUC-Tsy-119494	Tarsius syrichta	61.00	1.00e-55	209.00
IUUC-Tni-119663	Tetraodon nigroviridis	81.14	1.00e-114	405.00
IUUC-Tvi-122341	Trichoderma virens	60.71	9.00e-16	75.90
IUUC-Ttr-128442	Tursiops truncatus	60.93	6.00e-61	226.00
IUUC-Vpa-130063	Vicugna pacos	62.41	2.00e-77	282.00
IUUC-Xtr-132348	Xenopus tropicalis	86.25	2.00e-33	136.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence