iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033278

UUCD1 version

UUC-EqC-00300

Ensembl Protein ID

ENSECAP00000020263.1

UniProt Accession

F6UPG7; F6UPG7_HORSE

Protein Name

Uncharacterized protein

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000022670.1	ENSECAT00000024396.1	ENSECAP00000020263.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-23	81.8	367	398
UBD/Beta-Prp	2.00e-44	152.2	280	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++++t+s+d+   ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 280  KSHQGVVIAADWLVGGQQVVTASWDRAANLYDVQTAELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 368
           45666777799999**************************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 369  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 455
           ******99999.********************988874555555.55555555559*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 456  RRMVCCSAWSEDHpvCNLFTCGFDRQAIGWNIN 488
           ************9888899***********986 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MPTESGSCST ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELK RVIETLNERL TAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTATTGCC GGAGTGACCA GGACATCACC TTCTGGAAGT AATGCCCACA GAAAGCGGGA 60
GTTGTTCAAC TGCTCGCCAA GCAAAACAGA AACGCAAATC TCATAGCCTT TCTATACGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	96.57	0.00e+00	965.00
IUUC-Apl-003647	Anas platyrhynchos	91.94	0.00e+00	922.00
IUUC-Aca-004759	Anolis carolinensis	91.53	0.00e+00	934.00
IUUC-Ame-011103	Astyanax mexicanus	55.56	2.00e-142	498.00
IUUC-Bta-012718	Bos taurus	95.36	0.00e+00	956.00
IUUC-Cel-018499	Caenorhabditis elegans	42.05	2.00e-95	342.00
IUUC-Cja-019492	Callithrix jacchus	95.97	0.00e+00	986.00
IUUC-Cfa-020199	Canis familiaris	96.17	0.00e+00	996.00
IUUC-Cpo-022500	Cavia porcellus	89.92	0.00e+00	934.00
IUUC-Csa-023567	Chlorocebus sabaeus	96.57	0.00e+00	991.00
IUUC-Cho-025071	Choloepus hoffmanni	67.74	0.00e+00	638.00
IUUC-Cin-025460	Ciona intestinalis	44.54	3.00e-103	368.00
IUUC-Csv-026042	Ciona savignyi	45.98	3.00e-108	385.00
IUUC-Dre-028214	Danio rerio	82.06	0.00e+00	857.00
IUUC-Dno-029826	Dasypus novemcinctus	94.69	0.00e+00	817.00
IUUC-Dor-030967	Dipodomys ordii	95.81	0.00e+00	889.00
IUUC-Dme-031936	Drosophila melanogaster	49.27	2.00e-118	419.00
IUUC-Ete-032452	Echinops telfairi	91.94	0.00e+00	941.00
IUUC-Eeu-034592	Erinaceus europaeus	84.27	0.00e+00	834.00
IUUC-Fca-036431	Felis catus	97.18	0.00e+00	1001.00
IUUC-Fal-037149	Ficedula albicollis	90.93	0.00e+00	917.00
IUUC-Gmo-038476	Gadus morhua	77.82	0.00e+00	766.00
IUUC-Gga-041099	Gallus gallus	91.73	0.00e+00	923.00
IUUC-Gac-042374	Gasterosteus aculeatus	84.40	0.00e+00	820.00
IUUC-Ggo-044683	Gorilla gorilla	88.71	0.00e+00	902.00
IUUC-Hsa-046658	Homo sapiens	95.77	0.00e+00	985.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	96.48	0.00e+00	919.00
IUUC-Lch-050571	Latimeria chalumnae	83.49	0.00e+00	869.00
IUUC-Loc-052652	Lepisosteus oculatus	81.49	0.00e+00	858.00
IUUC-Laf-053712	Loxodonta africana	94.59	0.00e+00	973.00
IUUC-Mcc-055521	Macaca mulatta	96.57	0.00e+00	991.00
IUUC-Meu-056324	Macropus eugenii	88.51	0.00e+00	878.00
IUUC-Mga-060114	Meleagris gallopavo	91.94	0.00e+00	929.00
IUUC-Mmr-061176	Microcebus murinus	95.97	0.00e+00	986.00
IUUC-Mdo-061888	Monodelphis domestica	93.15	0.00e+00	915.00
IUUC-Mmu-063977	Mus musculus	95.97	0.00e+00	996.00
IUUC-Mpu-066220	Mustela putorius furo	83.96	0.00e+00	635.00
IUUC-Mlu-068155	Myotis lucifugus	97.58	0.00e+00	1007.00
IUUC-Nle-069964	Nomascus leucogenys	95.97	0.00e+00	987.00
IUUC-Opr-070925	Ochotona princeps	92.39	1.00e-147	515.00
IUUC-Ont-071317	Oreochromis niloticus	85.89	0.00e+00	843.00
IUUC-Oan-072952	Ornithorhynchus anatinus	94.35	0.00e+00	951.00
IUUC-Ocu-073913	Oryctolagus cuniculus	96.37	0.00e+00	998.00
IUUC-Ola-087024	Oryzias latipes	84.91	0.00e+00	881.00
IUUC-Oga-087945	Otolemur garnettii	95.56	0.00e+00	991.00
IUUC-Oar-089854	Ovis aries	95.36	0.00e+00	945.00
IUUC-Ptr-091486	Pan troglodytes	95.97	0.00e+00	986.00
IUUC-Pan-091738	Papio anubis	96.57	0.00e+00	991.00
IUUC-Psi-093953	Pelodiscus sinensis	91.33	0.00e+00	924.00
IUUC-Pma-094560	Petromyzon marinus	74.28	0.00e+00	759.00
IUUC-Pfo-097222	Poecilia formosa	84.07	0.00e+00	828.00
IUUC-Pab-098778	Pongo abelii	90.73	0.00e+00	921.00
IUUC-Pca-100852	Procavia capensis	91.33	0.00e+00	922.00
IUUC-Pva-103130	Pteropus vampyrus	96.69	2.00e-135	476.00
IUUC-Rno-105848	Rattus norvegicus	87.50	0.00e+00	885.00
IUUC-Sha-106750	Sarcophilus harrisii	93.35	0.00e+00	947.00
IUUC-Sar-113749	Sorex araneus	87.90	0.00e+00	884.00
IUUC-Ssc-115691	Sus scrofa	93.95	0.00e+00	935.00
IUUC-Tgu-117365	Taeniopygia guttata	90.32	0.00e+00	876.00
IUUC-Tru-117595	Takifugu rubripes	83.47	0.00e+00	828.00
IUUC-Tsy-118973	Tarsius syrichta	75.27	3.00e-152	531.00
IUUC-Tni-120545	Tetraodon nigroviridis	83.33	0.00e+00	865.00
IUUC-Tbe-127976	Tupaia belangeri	71.98	0.00e+00	696.00
IUUC-Ttr-128472	Tursiops truncatus	93.15	0.00e+00	948.00
IUUC-Xtr-132621	Xenopus tropicalis	89.72	0.00e+00	895.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence