iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028019

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-conjugating enzyme E2 variant 1

Genbank Nucleotide ID

CU928126

Gene Name

ube2v1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000041875.6	ENSDART00000067117.6	ENSDARP00000067116.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UEV	3.60e-60	202.9	22	161
E2/UBC	1.00e-19	71.6	48	154

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E2/UEV

   S: 6    elkvvvprnfrlleeleegekglgdgtvsygldDgddilllsltgtIigpertayegrIyqlklfvgkkYPekPPtvrfsskinmaevn 94
           ++ v+vprnfrlleeleeg+kg+gdgtvs+gl+D++d++l+++ g+Iigp+rt ye+r+y+l +++g++YPe PP+vrf++kin+++v 
   Q: 22   GSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWRGMIIGPPRTIYENRMYSLRVECGPRYPETPPFVRFVTKINLNGVH 110
           678************************************************************************************** PP
   S: 95   dsnGvvdpralpvLanWkreysievvlvqlkkellskenrklqqPpeGnlf 145
           +snGvvd ra++ La+W+++ysi+vvl++l++ ++ ken+kl+qPpeG+++
   Q: 111  NSNGVVDMRAVSSLAKWQNSYSIRVVLQELRRLMMCKENMKLPQPPEGQIY 161
           ************************************************986 PP

E2/UBC

   S: 16   gisakpvdesd..ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsvesv 101
           ++s +++d++d  lt+w+ +i+Gp++t+Ye+++++l++e+ ++YP +PP v+f+tki    v+++ G v +  + +  kW+  +s++ v
   Q: 48   TVSWGLEDDEDmtLTRWRGMIIGPPRTIYENRMYSLRVECGPRYPETPPFVRFVTKINLNGVHNSnGVVDMRAVSSLAKWQNSYSIRVV 136
           456667777776689*****************************************8766665555*******999************* PP
   S: 102  llsiqsll.aepnpespl 118
           l ++ +l+ ++ n++ p+
   Q: 137  LQELRRLMmCKENMKLPQ 154
           ******997788887776 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MRRLFTVGAS PLLSNKMAAA AGSGVKVPRN FRLLEELEEG QKGVGDGTVS WGLEDDEDMT 60
LTRWRGMIIG PPRTIYENRM YSLRVECGPR YPETPPFVRF VTKINLNGVH NSNGVVDMRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATAATT CATGAGGCGA TTGTTCACTG TTGGCGCGTC CCCGCTGCTG AGCAACAAGA 60
TGGCGGCCGC CGCCGGATCA GGTAAATTTA TGAAAAACTG CCTTTGTATC AGATTGTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0035370--C:UBC13-UEV1A complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003600	Anas platyrhynchos	89.29	4.00e-67	246.00
IUUC-Afl-008598	Aspergillus flavus	48.55	2.00e-32	131.00
IUUC-Aor-010051	Aspergillus oryzae	48.55	2.00e-32	131.00
IUUC-Ame-010710	Astyanax mexicanus	99.32	9.00e-85	305.00
IUUC-Bta-013403	Bos taurus	88.44	3.00e-70	256.00
IUUC-Cja-019316	Callithrix jacchus	88.44	3.00e-70	256.00
IUUC-Cfa-021118	Canis familiaris	89.29	3.00e-67	246.00
IUUC-Cne-026817	Cryptococcus neoformans	48.51	4.00e-37	147.00
IUUC-Dno-029762	Dasypus novemcinctus	89.36	1.00e-67	248.00
IUUC-Dor-030185	Dipodomys ordii	96.08	1.00e-24	106.00
IUUC-Dse-031272	Dothistroma septosporum	47.83	3.00e-32	130.00
IUUC-Dme-031635	Drosophila melanogaster	64.83	4.00e-57	213.00
IUUC-Eca-034422	Equus caballus	89.21	2.00e-66	244.00
IUUC-Fal-037350	Ficedula albicollis	89.36	8.00e-68	248.00
IUUC-Gmo-039237	Gadus morhua	89.80	5.00e-77	279.00
IUUC-Gac-042619	Gasterosteus aculeatus	82.01	2.00e-67	248.00
IUUC-Hsa-045659	Homo sapiens	88.44	3.00e-70	256.00
IUUC-Itr-048139	Ictidomys tridecemlineatus	89.29	4.00e-67	246.00
IUUC-Kpa-049337	Komagataella pastoris	49.63	9.00e-31	125.00
IUUC-Loc-052024	Lepisosteus oculatus	95.74	4.00e-79	288.00
IUUC-Laf-054176	Loxodonta africana	88.44	3.00e-70	256.00
IUUC-Mga-059951	Meleagris gallopavo	87.94	6.00e-67	246.00
IUUC-Mmr-061374	Microcebus murinus	82.31	1.00e-57	214.00
IUUC-Mpu-065775	Mustela putorius furo	88.44	3.00e-70	256.00
IUUC-Nle-069245	Nomascus leucogenys	88.44	3.00e-70	256.00
IUUC-Ont-071359	Oreochromis niloticus	89.80	3.00e-77	280.00
IUUC-Ocu-074447	Oryctolagus cuniculus	89.29	2.00e-67	247.00
IUUC-Ola-086519	Oryzias latipes	89.36	2.00e-74	272.00
IUUC-Oga-087972	Otolemur garnettii	89.29	5.00e-67	246.00
IUUC-Ptr-090866	Pan troglodytes	88.44	3.00e-70	256.00
IUUC-Pan-092804	Papio anubis	85.71	1.00e-67	248.00
IUUC-Pfo-097209	Poecilia formosa	88.44	1.00e-69	254.00
IUUC-Rno-106065	Rattus norvegicus	83.67	6.00e-66	242.00
IUUC-Sha-107363	Sarcophilus harrisii	85.71	9.00e-68	248.00
IUUC-Sar-113197	Sorex araneus	90.11	8.00e-47	180.00
IUUC-Ssc-115939	Sus scrofa	88.44	3.00e-70	256.00
IUUC-Tsy-119103	Tarsius syrichta	83.17	2.00e-47	182.00
IUUC-Tme-127171	Tuber melanosporum	45.99	8.00e-29	119.00
IUUC-Xtr-132359	Xenopus tropicalis	86.39	2.00e-67	247.00
IUUC-Xma-134032	Xiphophorus maculatus	88.44	1.00e-69	254.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence