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Tag Content
UUCD2 ID IUUC-Ssc-115495
UUCD1 version UUC-SuS-00370
Ensembl Protein ID ENSSSCP00000000518.2
UniProt Accession F1SH62; F1SH62_PIG
Genbank Protein ID ENSSSCP00000000518
Protein Name Uncharacterized protein
Genbank Nucleotide ID CU695219
Gene Name MDM2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000000488.2 ENSSSCT00000000526.2 ENSSSCP00000000518.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 93.48 0.00e+00 780.00 IUUC-Hsa-046376
E3 activity/RING/RING 79.03 0.00e+00 645.00 IUUC-Mmu-063207
E3 activity/RING/RING 81.43 0.00e+00 671.00 IUUC-Rno-105641
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Sus scrofa
Protein Sequence
(Fasta)
MCNTNMSVST DGAVSTSQIP ASEQETLVRP KPLLLKLLKS VGAQKDTYTM KEVIFYLGQY 60
IMTKRLYDEK QQHIVYCSND LLGDLFGVPS FSVKEHRKIY TMIYRNLIVV NQQEPSDSST 120
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Protein Fasta Sequence



>IUUC-Ssc-115495|E3,RING|Sus scrofa
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Nucleotide Sequence
(Fasta)
GCCGCGGCTT CCGGCGCGCT GGGCTCGGAC AGTAGGGGGC GCGCAGCTGG CGCACTTCAG 60
CCAGCTCGGC ACCTTCTGGG GCCTGTGCGG CTCGGTGTGA CTGGAAAGAA AATGGAGCAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ssc-115495|E3,RING|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005730--C:nucleolus
GO:0043234--C:protein complex
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0003283--P:atrial septum development
GO:0003181--P:atrioventricular valve morphogenesis
GO:0001568--P:blood vessel development
GO:0001974--P:blood vessel remodeling
GO:0060411--P:cardiac septum morphogenesis
GO:0071456--P:cellular response to hypoxia
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0003203--P:endocardial cushion morphogenesis
GO:0045184--P:establishment of protein localization
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0018205--P:peptidyl-lysine modification
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0006461--P:protein complex assembly
GO:0031648--P:protein destabilization
GO:0034504--P:protein localization to nucleus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0002027--P:regulation of heart rate
GO:0046677--P:response to antibiotic
GO:0007089--P:traversing start control point of mitotic cell cycle
GO:0003281--P:ventricular septum development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002039 Ailuropoda melanoleuca 94.30 0.00e+00 846.00
IUUC-Apl-003193 Anas platyrhynchos 64.23 3.00e-157 548.00
IUUC-Aca-004305 Anolis carolinensis 57.17 2.00e-122 432.00
IUUC-Ame-010675 Astyanax mexicanus 44.66 2.00e-83 302.00
IUUC-Bta-013270 Bos taurus 94.31 0.00e+00 825.00
IUUC-Cja-019744 Callithrix jacchus 90.87 0.00e+00 800.00
IUUC-Cfa-020807 Canis familiaris 92.86 0.00e+00 783.00
IUUC-Cpo-022182 Cavia porcellus 87.96 0.00e+00 750.00
IUUC-Cre-022828 Chlamydomonas reinhardtii 35.42 7.00e-06 41.20
IUUC-Csa-023541 Chlorocebus sabaeus 93.08 0.00e+00 808.00
IUUC-Cho-024831 Choloepus hoffmanni 75.37 3.00e-89 320.00
IUUC-Cin-025448 Ciona intestinalis 27.40 2.00e-19 88.60
IUUC-Csv-026151 Ciona savignyi 31.17 2.00e-11 62.40
IUUC-Dre-028419 Danio rerio 43.87 2.00e-51 196.00
IUUC-Dno-028950 Dasypus novemcinctus 92.06 0.00e+00 811.00
IUUC-Dor-031048 Dipodomys ordii 71.95 1.00e-172 598.00
IUUC-Ete-032264 Echinops telfairi 69.17 3.00e-174 604.00
IUUC-Eca-033301 Equus caballus 82.08 0.00e+00 731.00
IUUC-Eeu-035005 Erinaceus europaeus 81.06 0.00e+00 666.00
IUUC-Fca-035454 Felis catus 94.70 0.00e+00 840.00
IUUC-Fal-036720 Ficedula albicollis 62.13 3.00e-74 271.00
IUUC-Gmo-039296 Gadus morhua 40.67 1.00e-45 176.00
IUUC-Gga-040251 Gallus gallus 65.31 1.00e-153 536.00
IUUC-Gac-042397 Gasterosteus aculeatus 30.54 1.00e-46 180.00
IUUC-Ggo-044948 Gorilla gorilla 85.54 0.00e+00 734.00
IUUC-Hsa-046376 Homo sapiens 93.48 0.00e+00 814.00
IUUC-Itr-048328 Ictidomys tridecemlineatus 91.06 0.00e+00 776.00
IUUC-Lch-050037 Latimeria chalumnae 56.48 4.00e-117 414.00
IUUC-Loc-051837 Lepisosteus oculatus 50.20 2.00e-114 405.00
IUUC-Laf-053483 Loxodonta africana 85.77 0.00e+00 744.00
IUUC-Mcc-055294 Macaca mulatta 93.28 0.00e+00 812.00
IUUC-Meu-056294 Macropus eugenii 30.63 3.00e-25 109.00
IUUC-Mga-060007 Meleagris gallopavo 64.24 3.00e-146 511.00
IUUC-Mmr-060673 Microcebus murinus 92.67 0.00e+00 829.00
IUUC-Mdo-063057 Monodelphis domestica 75.56 0.00e+00 674.00
IUUC-Mmu-063207 Mus musculus 79.64 0.00e+00 637.00
IUUC-Mpu-065836 Mustela putorius furo 92.67 0.00e+00 841.00
IUUC-Mlu-068193 Myotis lucifugus 88.03 0.00e+00 791.00
IUUC-Nle-069927 Nomascus leucogenys 93.28 0.00e+00 812.00
IUUC-Opr-070590 Ochotona princeps 83.88 0.00e+00 716.00
IUUC-Ont-071984 Oreochromis niloticus 41.94 4.00e-52 198.00
IUUC-Oan-072744 Ornithorhynchus anatinus 72.40 8.00e-168 582.00
IUUC-Ocu-074071 Oryctolagus cuniculus 91.87 0.00e+00 798.00
IUUC-Ola-087329 Oryzias latipes 39.34 2.00e-70 259.00
IUUC-Oga-088135 Otolemur garnettii 82.22 0.00e+00 737.00
IUUC-Oar-090078 Ovis aries 94.30 0.00e+00 852.00
IUUC-Ptr-091399 Pan troglodytes 93.69 0.00e+00 815.00
IUUC-Pan-092720 Papio anubis 93.28 0.00e+00 812.00
IUUC-Psi-093591 Pelodiscus sinensis 64.99 8.00e-132 463.00
IUUC-Pma-094500 Petromyzon marinus 32.26 2.00e-24 104.00
IUUC-Pfo-096316 Poecilia formosa 40.04 6.00e-73 267.00
IUUC-Pab-097696 Pongo abelii 92.87 0.00e+00 802.00
IUUC-Pca-100974 Procavia capensis 82.72 0.00e+00 768.00
IUUC-Pva-102488 Pteropus vampyrus 87.78 0.00e+00 726.00
IUUC-Rno-105641 Rattus norvegicus 81.84 0.00e+00 682.00
IUUC-Sha-107314 Sarcophilus harrisii 73.33 0.00e+00 693.00
IUUC-Sar-112938 Sorex araneus 87.76 0.00e+00 793.00
IUUC-Tgu-116623 Taeniopygia guttata 66.74 8.00e-152 529.00
IUUC-Tru-117820 Takifugu rubripes 37.65 5.00e-69 254.00
IUUC-Tsy-119162 Tarsius syrichta 66.03 7.00e-91 327.00
IUUC-Tni-120204 Tetraodon nigroviridis 31.17 2.00e-49 189.00
IUUC-Tbe-127816 Tupaia belangeri 73.40 7.00e-126 443.00
IUUC-Ttr-129194 Tursiops truncatus 83.84 0.00e+00 683.00
IUUC-Vpa-130326 Vicugna pacos 89.21 0.00e+00 762.00
IUUC-Xtr-132216 Xenopus tropicalis 56.18 1.00e-121 429.00
Created Date 25-Jun-2017

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