iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062249

UUCD1 version

UUC-MoD-00494

Ensembl Protein ID

ENSMODP00000023997.2

UniProt Accession

F6ZHR2; F6ZHR2_MONDO

Protein Name

Uncharacterized protein

Gene Name

WSB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000019221.3	ENSMODT00000024423.3	ENSMODP00000023997.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-22	79.0	169	203
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.90e-14	52.8	357	402

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Htd v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 169  HTDVVRDLTFaPDgsLILVSASRDKTLRVWDLKDD 203
           ***********8875668*************9987 PP

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
           +++w+++ +++SLqhLCR+++rr + ++++   ++LP P++L ++L y+
   Q: 357  VYFWPTPKHVPSLQHLCRMSVRRVMSTWEV---QRLPVPPKLVEFLCYQ 402
           689***************************...*************987 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MASFPPRVNE KEIVRSRTIG ELLAPAAPFD KKCGHENWTV AFAPDGSYFA WSQGHRTVKL 60
VPWSRCLKNF LLDGTKNVTN SSNSRLSRQN SDGVSKNKPC EHVIDCGDIV WSLAFGSSVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAGCT TTCCCCCGAG GGTCAACGAG AAAGAGATCG GTGAGGAAGC CGGGGCCGAG 60
GGCGGGAGTG GGTGGTGCGT TCGACCTCTC CTCAGTATAG AAACTAGGAG GGCGGGGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG

mdo:100023969

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	80.05	0.00e+00	654.00
IUUC-Apl-003903	Anas platyrhynchos	76.34	0.00e+00	632.00
IUUC-Aca-005214	Anolis carolinensis	67.60	4.00e-165	573.00
IUUC-Ame-011740	Astyanax mexicanus	64.13	2.00e-158	551.00
IUUC-Bta-013475	Bos taurus	80.76	0.00e+00	658.00
IUUC-Cja-019053	Callithrix jacchus	79.05	0.00e+00	670.00
IUUC-Cfa-020103	Canis familiaris	79.33	0.00e+00	655.00
IUUC-Cpo-022438	Cavia porcellus	77.91	0.00e+00	666.00
IUUC-Csa-024062	Chlorocebus sabaeus	79.33	0.00e+00	675.00
IUUC-Cho-024334	Choloepus hoffmanni	69.83	2.00e-156	545.00
IUUC-Dre-028089	Danio rerio	64.00	2.00e-157	548.00
IUUC-Dno-029436	Dasypus novemcinctus	73.50	1.00e-143	503.00
IUUC-Dor-031107	Dipodomys ordii	73.63	3.00e-168	584.00
IUUC-Ete-032326	Echinops telfairi	78.13	2.00e-178	618.00
IUUC-Eca-033401	Equus caballus	79.81	0.00e+00	651.00
IUUC-Eeu-034520	Erinaceus europaeus	77.91	0.00e+00	662.00
IUUC-Fca-036386	Felis catus	80.29	0.00e+00	657.00
IUUC-Fal-036616	Ficedula albicollis	74.51	2.00e-176	611.00
IUUC-Gmo-039335	Gadus morhua	62.90	3.00e-144	504.00
IUUC-Gga-040856	Gallus gallus	76.18	0.00e+00	654.00
IUUC-Gac-042140	Gasterosteus aculeatus	65.02	1.00e-155	542.00
IUUC-Ggo-044619	Gorilla gorilla	79.57	0.00e+00	677.00
IUUC-Hsa-046300	Homo sapiens	79.10	0.00e+00	672.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	79.33	0.00e+00	676.00
IUUC-Lch-049550	Latimeria chalumnae	69.36	9.00e-137	479.00
IUUC-Loc-051769	Lepisosteus oculatus	66.27	5.00e-158	550.00
IUUC-Laf-054576	Loxodonta africana	79.81	0.00e+00	659.00
IUUC-Mcc-054666	Macaca mulatta	71.76	2.00e-104	371.00
IUUC-Meu-055989	Macropus eugenii	79.04	8.00e-157	546.00
IUUC-Mga-059722	Meleagris gallopavo	74.64	0.00e+00	639.00
IUUC-Mmr-060970	Microcebus murinus	79.10	0.00e+00	650.00
IUUC-Mmu-063742	Mus musculus	77.14	0.00e+00	649.00
IUUC-Mpu-066518	Mustela putorius furo	80.52	0.00e+00	680.00
IUUC-Mlu-068063	Myotis lucifugus	78.62	0.00e+00	645.00
IUUC-Nle-069561	Nomascus leucogenys	78.86	0.00e+00	673.00
IUUC-Opr-071158	Ochotona princeps	78.33	0.00e+00	658.00
IUUC-Ont-072542	Oreochromis niloticus	63.15	3.00e-155	541.00
IUUC-Oan-073217	Ornithorhynchus anatinus	80.19	0.00e+00	670.00
IUUC-Ocu-074251	Oryctolagus cuniculus	78.97	0.00e+00	637.00
IUUC-Ola-086549	Oryzias latipes	61.97	7.00e-153	533.00
IUUC-Oga-088382	Otolemur garnettii	79.10	0.00e+00	662.00
IUUC-Oar-090263	Ovis aries	78.81	0.00e+00	664.00
IUUC-Ptr-090922	Pan troglodytes	79.33	0.00e+00	674.00
IUUC-Pan-092518	Papio anubis	79.33	0.00e+00	675.00
IUUC-Psi-093512	Pelodiscus sinensis	76.89	0.00e+00	651.00
IUUC-Pma-094324	Petromyzon marinus	50.69	7.00e-106	377.00
IUUC-Pfo-096264	Poecilia formosa	63.15	3.00e-155	541.00
IUUC-Pab-098018	Pongo abelii	77.91	0.00e+00	660.00
IUUC-Pca-101034	Procavia capensis	79.26	0.00e+00	626.00
IUUC-Pva-102862	Pteropus vampyrus	77.25	1.00e-175	609.00
IUUC-Rno-106116	Rattus norvegicus	76.96	0.00e+00	649.00
IUUC-Sha-106952	Sarcophilus harrisii	83.98	0.00e+00	661.00
IUUC-Sar-113211	Sorex araneus	64.04	2.00e-112	398.00
IUUC-Ssc-116440	Sus scrofa	80.05	0.00e+00	655.00
IUUC-Tgu-116675	Taeniopygia guttata	73.77	1.00e-175	608.00
IUUC-Tru-118295	Takifugu rubripes	62.91	6.00e-150	523.00
IUUC-Tsy-118916	Tarsius syrichta	65.70	1.00e-156	546.00
IUUC-Tni-120302	Tetraodon nigroviridis	63.15	2.00e-150	525.00
IUUC-Tbe-127416	Tupaia belangeri	63.72	2.00e-148	518.00
IUUC-Ttr-128185	Tursiops truncatus	80.29	0.00e+00	655.00
IUUC-Xtr-132465	Xenopus tropicalis	72.88	1.00e-178	619.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence