iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022272

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02057401

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000012506.3	ENSCPOT00000012625.2	ENSCPOP00000011251.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-65	221.8	390	762

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 390  GLINKGNWCYINATLQALVACPPMYHLMKF-IPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 476
           9***************************99.333333.334799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsdeaeekkkkknk... 139
            +++ l   ++++s + +q+Da+E+l f+l++l+ee+ +                  ++ + + ee+e+ se s+e++e+   +nk   
   Q: 477  YIYRLLTVSKSSLSeKGRQEDAEEYLGFVLNGLHEEMLSlkkllspgstkllvsngPRSPSADGEEQEAGSEGSEEEWEQVGPRNKtsv 565
           ******99999966599********************5566688888889997777333333333333334444444444444444444 PP
   S: 140  ........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekk 220
                   ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g   y +++ ++ +e +++
   Q: 566  trqadfvqTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG---YTTKTKQEVVEISRR 647
           44555666***********9.688999999*******************99...****************9...99999999******* PP
   S: 221  lklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.Wl 307
           ++l+klP+vL+lhLkRf ++++++++ k+ k++e+p  L++s+ + sp      +++Y+L+avv+H+G s+ +GHY+++v +   + Wl
   Q: 648  VTLEKLPPVLVLHLKRFVYEKTGGCQ-KLAKNIEYPVDLEISRELLSPGC----HRTYRLFAVVYHHGsSATGGHYTTDVFQIGLNgWL 731
           *******************9998886.***************98888663....78**************************87777** PP
   S: 308  lfdDskVtevkeeevleetg.staYvlfYkr 337
           ++dD++V++v++++vl+  + ++aY+l+Y+r
   Q: 732  RMDDQSVRVVPQHQVLRPAAeRSAYLLYYRR 762
           *****************7778********98 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

CDVEWPQYIF GDFSPDEFNQ FFVTPRSSVE LPPYSGTALC GNQAVDELPD GTGPAYQRIE 60
FGGTDEVEPS DGLPSAPGCS ISSTLNPQAP EFILGCTASK KSPQGPGQEA TPHCLEQPGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGATGTGG AGTGGCCGCA GGTGGGTGGC GGGAGGAGGG CCCAGGGCCC GGCCGGCCGC 60
GCGCGCGGAC TGCCGTTTGG GAGGGGTGCC GTGGTGTATG TTGTGTGTGA TGGGTGGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	31.22	7.00e-44	172.00
IUUC-Aml-001584	Ailuropoda melanoleuca	73.99	0.00e+00	1041.00
IUUC-Atr-002927	Amborella trichopoda	37.40	8.00e-59	221.00
IUUC-Apl-003988	Anas platyrhynchos	67.38	0.00e+00	937.00
IUUC-Aca-004461	Anolis carolinensis	86.57	2.00e-154	538.00
IUUC-Aly-006038	Arabidopsis lyrata	35.32	6.00e-53	201.00
IUUC-Ath-007328	Arabidopsis thaliana	35.66	6.00e-52	198.00
IUUC-Ago-007717	Ashbya gossypii	27.83	4.00e-41	163.00
IUUC-Acl-008188	Aspergillus clavatus	33.89	3.00e-61	230.00
IUUC-Afl-008456	Aspergillus flavus	39.07	2.00e-46	180.00
IUUC-Afu-009067	Aspergillus fumigatus	35.63	1.00e-64	241.00
IUUC-Ani-009483	Aspergillus nidulans	33.73	3.00e-63	236.00
IUUC-Ang-009639	Aspergillus niger	35.22	5.00e-59	223.00
IUUC-Aor-010040	Aspergillus oryzae	35.27	6.00e-59	222.00
IUUC-Ate-010310	Aspergillus terreus	35.24	1.00e-59	224.00
IUUC-Ame-011012	Astyanax mexicanus	70.05	4.00e-150	525.00
IUUC-Bgr-012311	Blumeria graminis	35.14	3.00e-44	173.00
IUUC-Bta-013299	Bos taurus	73.97	0.00e+00	1011.00
IUUC-Bci-013783	Botrytis cinerea	36.41	2.00e-56	214.00
IUUC-Bdi-015039	Brachypodium distachyon	32.92	1.00e-49	191.00
IUUC-Bol-015806	Brassica oleracea	36.10	1.00e-60	227.00
IUUC-Bra-017076	Brassica rapa	36.36	3.00e-61	229.00
IUUC-Cja-018715	Callithrix jacchus	75.16	0.00e+00	1065.00
IUUC-Cfa-020194	Canis familiaris	73.62	0.00e+00	1048.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	36.15	1.00e-33	138.00
IUUC-Csa-023310	Chlorocebus sabaeus	75.25	0.00e+00	1068.00
IUUC-Cho-024966	Choloepus hoffmanni	62.82	0.00e+00	680.00
IUUC-Cin-025616	Ciona intestinalis	44.94	3.00e-99	355.00
IUUC-Csv-026043	Ciona savignyi	45.24	1.00e-93	336.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	33.67	2.00e-45	177.00
IUUC-Cne-026962	Cryptococcus neoformans	35.99	8.00e-50	192.00
IUUC-Cme-027113	Cyanidioschyzon merolae	30.00	9.00e-35	141.00
IUUC-Dre-028072	Danio rerio	74.03	0.00e+00	668.00
IUUC-Dno-029489	Dasypus novemcinctus	73.81	0.00e+00	1060.00
IUUC-Dor-031068	Dipodomys ordii	67.20	2.00e-128	453.00
IUUC-Dse-031553	Dothistroma septosporum	36.64	2.00e-53	204.00
IUUC-Dme-031759	Drosophila melanogaster	42.34	3.00e-83	304.00
IUUC-Ete-032549	Echinops telfairi	66.51	0.00e+00	704.00
IUUC-Eca-033380	Equus caballus	72.77	0.00e+00	1037.00
IUUC-Eeu-034818	Erinaceus europaeus	70.64	0.00e+00	1003.00
IUUC-Fca-035535	Felis catus	72.31	0.00e+00	920.00
IUUC-Fal-036627	Ficedula albicollis	67.51	0.00e+00	913.00
IUUC-Fox-037904	Fusarium oxysporum	36.68	4.00e-53	202.00
IUUC-Fso-038170	Fusarium solani	35.02	2.00e-51	197.00
IUUC-Gmo-039499	Gadus morhua	70.76	0.00e+00	629.00
IUUC-Ggr-040042	Gaeumannomyces graminis	36.60	6.00e-60	226.00
IUUC-Gga-040571	Gallus gallus	68.26	0.00e+00	941.00
IUUC-Gac-041345	Gasterosteus aculeatus	73.33	0.00e+00	637.00
IUUC-Gma-044407	Glycine max	36.20	2.00e-57	216.00
IUUC-Ggo-044652	Gorilla gorilla	75.41	0.00e+00	1092.00
IUUC-Hsa-045864	Homo sapiens	75.66	0.00e+00	1097.00
IUUC-Hvu-047071	Hordeum vulgare	34.01	1.00e-51	197.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	80.52	0.00e+00	854.00
IUUC-Kpa-049132	Komagataella pastoris	30.16	2.00e-43	170.00
IUUC-Lch-050040	Latimeria chalumnae	62.38	0.00e+00	770.00
IUUC-Loc-052449	Lepisosteus oculatus	72.42	0.00e+00	668.00
IUUC-Lma-053248	Leptosphaeria maculans	35.75	6.00e-55	209.00
IUUC-Laf-054121	Loxodonta africana	73.62	0.00e+00	1046.00
IUUC-Mcc-055514	Macaca mulatta	75.25	0.00e+00	1066.00
IUUC-Meu-056873	Macropus eugenii	61.85	1.00e-178	620.00
IUUC-Mor-057243	Magnaporthe oryzae	35.16	6.00e-57	216.00
IUUC-Mpo-057439	Magnaporthe poae	37.14	3.00e-60	227.00
IUUC-Mtr-058457	Medicago truncatula	35.23	4.00e-55	209.00
IUUC-Mla-058929	Melampsora laricipopulina	30.20	2.00e-53	204.00
IUUC-Mga-060157	Meleagris gallopavo	66.96	0.00e+00	934.00
IUUC-Mvi-060442	Microbotryum violaceum	34.58	4.00e-53	203.00
IUUC-Mmr-061062	Microcebus murinus	74.00	0.00e+00	1078.00
IUUC-Mdo-062798	Monodelphis domestica	70.06	0.00e+00	976.00
IUUC-Mmu-064050	Mus musculus	73.23	0.00e+00	1046.00
IUUC-Mac-065619	Musa acuminata	36.34	1.00e-53	203.00
IUUC-Mpu-066554	Mustela putorius furo	73.65	0.00e+00	1027.00
IUUC-Mlu-068003	Myotis lucifugus	72.02	0.00e+00	1017.00
IUUC-Nfi-068612	Neosartorya fischeri	35.18	2.00e-63	237.00
IUUC-Ncr-068878	Neurospora crassa	34.88	2.00e-49	191.00
IUUC-Nle-069661	Nomascus leucogenys	75.78	0.00e+00	1078.00
IUUC-Opr-070944	Ochotona princeps	79.63	6.00e-153	534.00
IUUC-Ont-071266	Oreochromis niloticus	74.47	0.00e+00	657.00
IUUC-Oan-073442	Ornithorhynchus anatinus	68.31	0.00e+00	927.00
IUUC-Ocu-073788	Oryctolagus cuniculus	71.08	0.00e+00	917.00
IUUC-Oba-075085	Oryza barthii	34.07	7.00e-36	143.00
IUUC-Obr-076663	Oryza brachyantha	33.07	7.00e-43	168.00
IUUC-Ogl-076937	Oryza glaberrima	30.81	8.00e-47	181.00
IUUC-Ogu-078909	Oryza glumaepatula	30.40	1.00e-44	174.00
IUUC-Oin-079617	Oryza indica	31.91	1.00e-45	177.00
IUUC-Olo-081043	Oryza longistaminata	26.16	5.00e-23	102.00
IUUC-Ome-081646	Oryza meridionalis	24.74	9.00e-22	98.60
IUUC-Oni-082914	Oryza nivara	30.40	1.00e-44	174.00
IUUC-Oru-084878	Oryza rufipogon	30.40	1.00e-44	174.00
IUUC-Osa-085822	Oryza sativa	31.95	1.00e-48	187.00
IUUC-Ola-086931	Oryzias latipes	69.40	0.00e+00	630.00
IUUC-Oga-088443	Otolemur garnettii	74.06	0.00e+00	1087.00
IUUC-Oar-089325	Ovis aries	73.01	0.00e+00	956.00
IUUC-Ptr-091584	Pan troglodytes	74.43	0.00e+00	1032.00
IUUC-Pan-092551	Papio anubis	73.65	0.00e+00	1035.00
IUUC-Psi-093366	Pelodiscus sinensis	65.65	3.00e-156	544.00
IUUC-Pno-095136	Phaeosphaeria nodorum	35.23	3.00e-51	196.00
IUUC-Ppa-095574	Physcomitrella patens	38.50	5.00e-58	218.00
IUUC-Pfo-097462	Poecilia formosa	74.95	0.00e+00	661.00
IUUC-Pab-098547	Pongo abelii	75.66	0.00e+00	1075.00
IUUC-Pop-099529	Populus trichocarpa	36.08	5.00e-59	222.00
IUUC-Pca-101066	Procavia capensis	64.91	0.00e+00	884.00
IUUC-Ppe-102110	Prunus persica	36.69	3.00e-56	212.00
IUUC-Pva-103015	Pteropus vampyrus	69.05	0.00e+00	961.00
IUUC-Ptt-103998	Puccinia triticina	32.50	1.00e-48	187.00
IUUC-Pte-104417	Pyrenophora teres	34.19	3.00e-53	203.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	34.64	1.00e-52	201.00
IUUC-Rno-105533	Rattus norvegicus	73.77	0.00e+00	1049.00
IUUC-Sce-106160	Saccharomyces cerevisiae	26.92	2.00e-35	144.00
IUUC-Sha-106590	Sarcophilus harrisii	70.35	0.00e+00	970.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	33.96	1.00e-54	207.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.41	2.00e-61	229.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	35.82	2.00e-56	213.00
IUUC-Smo-108842	Selaginella moellendorffii	36.13	4.00e-36	144.00
IUUC-Sit-110781	Setaria italica	33.26	2.00e-55	210.00
IUUC-Sly-111797	Solanum lycopersicum	36.01	3.00e-56	213.00
IUUC-Stu-112188	Solanum tuberosum	36.92	3.00e-57	216.00
IUUC-Sbi-114862	Sorghum bicolor	32.53	4.00e-43	169.00
IUUC-Sre-115162	Sporisorium reilianum	35.71	8.00e-65	241.00
IUUC-Ssc-115505	Sus scrofa	88.39	2.00e-151	527.00
IUUC-Tgu-116535	Taeniopygia guttata	66.88	0.00e+00	917.00
IUUC-Tru-117542	Takifugu rubripes	73.82	0.00e+00	665.00
IUUC-Tni-120200	Tetraodon nigroviridis	73.61	0.00e+00	659.00
IUUC-Tca-121548	Theobroma cacao	34.92	2.00e-41	163.00
IUUC-Tre-122124	Trichoderma reesei	32.85	7.00e-59	222.00
IUUC-Tvi-122457	Trichoderma virens	35.39	1.00e-50	195.00
IUUC-Tae-125646	Triticum aestivum	34.45	6.00e-54	205.00
IUUC-Tme-127180	Tuber melanosporum	41.03	9.00e-70	258.00
IUUC-Tbe-127530	Tupaia belangeri	64.44	0.00e+00	836.00
IUUC-Ttr-128549	Tursiops truncatus	66.58	0.00e+00	909.00
IUUC-Uma-129381	Ustilago maydis	35.14	1.00e-64	241.00
IUUC-Vda-129889	Verticillium dahliae	33.06	8.00e-50	192.00
IUUC-Vpa-130100	Vicugna pacos	68.26	0.00e+00	902.00
IUUC-Vvi-131366	Vitis vinifera	37.53	2.00e-61	230.00
IUUC-Xtr-132048	Xenopus tropicalis	57.42	0.00e+00	781.00
IUUC-Xma-133593	Xiphophorus maculatus	74.52	0.00e+00	658.00
IUUC-Yli-134338	Yarrowia lipolytica	25.98	3.00e-30	127.00
IUUC-Zma-135586	Zea mays	32.49	3.00e-46	179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence