iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042499

UUCD1 version

UUC-GaA-00572

Ensembl Protein ID

ENSGACP00000015162.1

UniProt Accession

G3PC38; G3PC38_GASAC

Protein Name

Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat-containing protein 39

Gene Name

ciao1; CIAO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000011448.1	ENSGACT00000015191.1	ENSGACP00000015162.1
ENSGACG00000011448.1	ENSGACT00000015193.1	ENSGACP00000015164.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-40	136.2	300	331
UBD/Beta-Prp	6.80e-88	295.1	55	277

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDl 30
           H+ +v+c+a+   + +ll+s+sdDg i +W++
   Q: 300  HSQDVNCVAWnpKEaGLLASCSDDGGISIWRF 331
           9**********65599**************96 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdls...tgkcv 87
           +l++ h+  ++ v++sp +++la++s d+t+ +w+ ++ ++  l  l+ghe+ev++v + p+g++l+t+s+D+ + vw+++    ++cv
   Q: 55   VLQDGHQRTVRRVAWSPCGNYLASASFDATTCIWKKKNDDFesLTVLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDeddEYECV 143
           578888999999**************************999988999*******************************8887789**** PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......... 166
            +++ h+++v  + ++p+++ l+s+s d+ + +++ e + +    tl+gh+++v++++++ +g+ l+s+s+Drtv++W+          
   Q: 144  TVVNSHTQDVKNIVWHPTQELLASASYDNNVCIYKEEDDDWECRaTLQGHTSTVWSLAFDATGQRLASCSDDRTVKIWKEspnesgqas 232
           **********************************99887665545**********************************9********* PP
   S: 167  ....ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklw 207
                  k++ tl+g+h + vy +s+ +    l+++  d  v+++
   Q: 233  tqrdLLWKCVCTLSGYHGRTVYDISWCRLTGALATACGDDAVRVF 277
           9999999********************999999999999999986 PP

Organism

Gasterosteus aculeatus

Functional Description
(View)

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MKAGLSPVQT LNAHPDSRCW FVGWSPSGTL LASCGGDKAI RIWGREGDSW ICKSVLQDGH 60
QRTVRRVAWS PCGNYLASAS FDATTCIWKK KNDDFESLTV LEGHENEVKS VAWAPSGNLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGCAAACAT GGCGGCGATC CCCACCCGTT TGTTTTTTTG AACTTGTCTA CTTTGAAGCG 60
ACTCCTACGC TTCCTTTTCC ACGCTATCTT CGAGTTGACC CGTTATTCAG ACAGCTCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	47.21	5.00e-68	252.00
IUUC-Aml-001317	Ailuropoda melanoleuca	74.18	4.00e-140	490.00
IUUC-Atr-003029	Amborella trichopoda	50.00	1.00e-91	329.00
IUUC-Apl-004042	Anas platyrhynchos	59.09	5.00e-40	155.00
IUUC-Aly-005812	Arabidopsis lyrata	47.80	9.00e-85	306.00
IUUC-Ath-006671	Arabidopsis thaliana	47.81	1.00e-85	309.00
IUUC-Ago-007820	Ashbya gossypii	41.89	2.00e-60	226.00
IUUC-Acl-008042	Aspergillus clavatus	30.47	1.00e-46	180.00
IUUC-Afl-008639	Aspergillus flavus	31.98	5.00e-52	198.00
IUUC-Afu-008899	Aspergillus fumigatus	29.22	4.00e-47	182.00
IUUC-Ani-009453	Aspergillus nidulans	31.09	3.00e-48	186.00
IUUC-Ang-009758	Aspergillus niger	39.44	1.00e-43	170.00
IUUC-Aor-010212	Aspergillus oryzae	31.98	5.00e-52	198.00
IUUC-Ate-010314	Aspergillus terreus	31.01	3.00e-48	185.00
IUUC-Ame-010676	Astyanax mexicanus	79.04	1.00e-159	555.00
IUUC-Bgr-012095	Blumeria graminis	29.18	4.00e-36	145.00
IUUC-Bta-012884	Bos taurus	74.48	2.00e-140	491.00
IUUC-Bci-013622	Botrytis cinerea	30.55	5.00e-34	138.00
IUUC-Bdi-014614	Brachypodium distachyon	46.92	5.00e-86	311.00
IUUC-Bol-016439	Brassica oleracea	46.76	7.00e-82	297.00
IUUC-Bra-016830	Brassica rapa	46.29	1.00e-81	296.00
IUUC-Cel-018709	Caenorhabditis elegans	41.23	2.00e-64	239.00
IUUC-Cja-019822	Callithrix jacchus	75.07	1.00e-140	492.00
IUUC-Cfa-020823	Canis familiaris	74.18	1.00e-140	492.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	45.56	9.00e-79	286.00
IUUC-Csa-023754	Chlorocebus sabaeus	74.78	1.00e-140	492.00
IUUC-Cin-025395	Ciona intestinalis	56.42	9.00e-111	393.00
IUUC-Csv-025943	Ciona savignyi	54.05	4.00e-106	377.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	31.99	1.00e-33	137.00
IUUC-Cne-026939	Cryptococcus neoformans	30.25	2.00e-45	176.00
IUUC-Cme-027239	Cyanidioschyzon merolae	39.68	2.00e-43	169.00
IUUC-Dre-028172	Danio rerio	76.51	3.00e-156	544.00
IUUC-Dno-029472	Dasypus novemcinctus	74.91	2.00e-119	421.00
IUUC-Dor-031134	Dipodomys ordii	64.09	9.00e-113	399.00
IUUC-Dse-031535	Dothistroma septosporum	27.96	6.00e-43	168.00
IUUC-Dme-032020	Drosophila melanogaster	59.27	9.00e-116	409.00
IUUC-Eca-033700	Equus caballus	74.48	2.00e-141	494.00
IUUC-Eeu-035010	Erinaceus europaeus	72.11	3.00e-135	474.00
IUUC-Fca-036309	Felis catus	67.46	1.00e-131	462.00
IUUC-Fal-037243	Ficedula albicollis	65.58	2.00e-76	278.00
IUUC-Fox-038058	Fusarium oxysporum	30.73	8.00e-40	158.00
IUUC-Fso-038459	Fusarium solani	33.44	8.00e-38	151.00
IUUC-Gmo-039375	Gadus morhua	79.58	3.00e-147	514.00
IUUC-Ggr-040002	Gaeumannomyces graminis	33.14	5.00e-36	145.00
IUUC-Gga-040294	Gallus gallus	71.43	1.00e-107	382.00
IUUC-Gma-043543	Glycine max	46.33	8.00e-86	310.00
IUUC-Ggo-045181	Gorilla gorilla	74.78	1.00e-140	492.00
IUUC-Hsa-046528	Homo sapiens	74.78	1.00e-140	492.00
IUUC-Hvu-047341	Hordeum vulgare	53.33	1.00e-53	202.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	74.78	7.00e-141	493.00
IUUC-Kpa-049353	Komagataella pastoris	34.73	7.00e-52	197.00
IUUC-Lch-049763	Latimeria chalumnae	72.32	2.00e-141	495.00
IUUC-Lpe-051500	Leersia perrieri	43.50	9.00e-84	303.00
IUUC-Loc-052021	Lepisosteus oculatus	75.89	1.00e-141	495.00
IUUC-Lma-053331	Leptosphaeria maculans	32.50	2.00e-50	194.00
IUUC-Laf-054558	Loxodonta africana	73.89	1.00e-139	489.00
IUUC-Mcc-055374	Macaca mulatta	74.78	1.00e-140	492.00
IUUC-Meu-056042	Macropus eugenii	61.25	3.00e-85	308.00
IUUC-Mor-057187	Magnaporthe oryzae	30.57	3.00e-37	149.00
IUUC-Mtr-058072	Medicago truncatula	48.08	2.00e-88	318.00
IUUC-Mla-059108	Melampsora laricipopulina	31.76	2.00e-51	196.00
IUUC-Mga-059370	Meleagris gallopavo	54.93	5.00e-83	300.00
IUUC-Mvi-060495	Microbotryum violaceum	38.01	2.00e-57	216.00
IUUC-Mmr-060902	Microcebus murinus	74.48	8.00e-141	493.00
IUUC-Mdo-062510	Monodelphis domestica	73.29	6.00e-134	470.00
IUUC-Mmu-063575	Mus musculus	74.33	2.00e-138	484.00
IUUC-Mac-065322	Musa acuminata	50.15	2.00e-92	332.00
IUUC-Mpu-065925	Mustela putorius furo	73.89	1.00e-140	492.00
IUUC-Mlu-067755	Myotis lucifugus	74.33	4.00e-139	487.00
IUUC-Nfi-068327	Neosartorya fischeri	30.09	2.00e-45	176.00
IUUC-Ncr-068845	Neurospora crassa	31.06	6.00e-28	118.00
IUUC-Nle-069406	Nomascus leucogenys	73.59	6.00e-136	476.00
IUUC-Opr-070416	Ochotona princeps	81.60	1.00e-66	246.00
IUUC-Ont-071936	Oreochromis niloticus	88.06	1.00e-163	568.00
IUUC-Oan-073452	Ornithorhynchus anatinus	72.73	2.00e-55	207.00
IUUC-Ocu-074791	Oryctolagus cuniculus	73.59	4.00e-139	487.00
IUUC-Oba-075636	Oryza barthii	47.66	4.00e-89	321.00
IUUC-Obr-076742	Oryza brachyantha	48.24	5.00e-78	283.00
IUUC-Ogl-077766	Oryza glaberrima	47.66	4.00e-89	321.00
IUUC-Ogu-079039	Oryza glumaepatula	47.66	1.00e-89	322.00
IUUC-Oin-079315	Oryza indica	47.59	4.00e-78	284.00
IUUC-Olo-080669	Oryza longistaminata	42.42	2.00e-81	295.00
IUUC-Ome-081490	Oryza meridionalis	47.66	2.00e-89	322.00
IUUC-Oni-082572	Oryza nivara	47.66	4.00e-89	321.00
IUUC-Opu-083732	Oryza punctata	48.54	3.00e-91	328.00
IUUC-Oru-084763	Oryza rufipogon	47.66	4.00e-89	321.00
IUUC-Osa-085372	Oryza sativa	47.66	4.00e-89	321.00
IUUC-Ola-087379	Oryzias latipes	85.42	1.00e-157	548.00
IUUC-Olu-087801	Ostreococcus lucimarinus	37.15	1.00e-43	170.00
IUUC-Oga-089076	Otolemur garnettii	74.78	2.00e-141	494.00
IUUC-Oar-090022	Ovis aries	74.48	4.00e-142	497.00
IUUC-Ptr-090809	Pan troglodytes	74.78	1.00e-140	492.00
IUUC-Pan-091685	Papio anubis	74.78	8.00e-142	497.00
IUUC-Psi-093046	Pelodiscus sinensis	71.22	6.00e-137	480.00
IUUC-Pma-094181	Petromyzon marinus	62.13	8.00e-126	443.00
IUUC-Pno-094882	Phaeosphaeria nodorum	31.08	2.00e-51	196.00
IUUC-Ppa-095172	Physcomitrella patens	48.09	5.00e-86	311.00
IUUC-Pfo-096396	Poecilia formosa	84.18	1.00e-158	551.00
IUUC-Pab-098427	Pongo abelii	74.48	2.00e-138	485.00
IUUC-Pop-100016	Populus trichocarpa	50.44	2.00e-91	328.00
IUUC-Pca-101048	Procavia capensis	74.18	8.00e-140	489.00
IUUC-Ppe-102050	Prunus persica	47.28	8.00e-87	313.00
IUUC-Pva-103117	Pteropus vampyrus	73.89	5.00e-140	490.00
IUUC-Pgr-103307	Puccinia graminis	34.10	1.00e-56	213.00
IUUC-Ptt-103938	Puccinia triticina	37.02	7.00e-47	180.00
IUUC-Pte-104315	Pyrenophora teres	32.62	3.00e-52	199.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	32.78	2.00e-52	199.00
IUUC-Rno-105523	Rattus norvegicus	74.93	2.00e-139	488.00
IUUC-Sce-106297	Saccharomyces cerevisiae	38.12	1.00e-59	223.00
IUUC-Sha-106981	Sarcophilus harrisii	74.23	6.00e-114	403.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	37.69	4.00e-53	202.00
IUUC-Spo-108214	Schizosaccharomyces pombe	41.64	5.00e-60	225.00
IUUC-Smo-109034	Selaginella moellendorffii	46.37	3.00e-85	308.00
IUUC-Sit-110663	Setaria italica	47.93	5.00e-90	324.00
IUUC-Sly-110898	Solanum lycopersicum	46.76	3.00e-81	295.00
IUUC-Stu-112647	Solanum tuberosum	49.81	5.00e-70	257.00
IUUC-Sbi-114288	Sorghum bicolor	46.47	6.00e-87	313.00
IUUC-Sre-115065	Sporisorium reilianum	39.20	2.00e-66	246.00
IUUC-Ssc-115960	Sus scrofa	70.03	4.00e-142	497.00
IUUC-Tru-118382	Takifugu rubripes	82.34	2.00e-164	571.00
IUUC-Tsy-119585	Tarsius syrichta	66.47	3.00e-120	424.00
IUUC-Tni-120133	Tetraodon nigroviridis	83.64	6.00e-156	543.00
IUUC-Tca-121167	Theobroma cacao	48.10	2.00e-81	295.00
IUUC-Tre-122119	Trichoderma reesei	28.57	3.00e-38	152.00
IUUC-Tvi-122407	Trichoderma virens	29.66	4.00e-39	155.00
IUUC-Tae-125748	Triticum aestivum	46.20	2.00e-83	302.00
IUUC-Tur-126682	Triticum urartu	47.73	1.00e-68	253.00
IUUC-Tme-127095	Tuber melanosporum	35.16	4.00e-59	221.00
IUUC-Tbe-128004	Tupaia belangeri	74.18	8.00e-140	489.00
IUUC-Ttr-129284	Tursiops truncatus	73.29	5.00e-135	473.00
IUUC-Uma-129527	Ustilago maydis	39.57	1.00e-66	247.00
IUUC-Vda-129854	Verticillium dahliae	30.58	3.00e-36	145.00
IUUC-Vpa-130681	Vicugna pacos	88.79	3.00e-46	178.00
IUUC-Vvi-131004	Vitis vinifera	51.94	3.00e-87	315.00
IUUC-Xtr-131928	Xenopus tropicalis	70.75	1.00e-134	472.00
IUUC-Xma-134290	Xiphophorus maculatus	83.28	5.00e-156	543.00
IUUC-Yli-134364	Yarrowia lipolytica	40.70	1.00e-61	230.00
IUUC-Zma-135658	Zea mays	46.51	1.00e-86	312.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence