iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087379

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat-containing protein 39

Genbank Nucleotide ID

BAAF04026833

Gene Name

ciao1; CIAO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000012229.1	ENSORLT00000015306.1	ENSORLP00000015305.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-40	136.1	103	135
UBD/Beta-Prp	7.30e-78	262.1	55	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH+++v c+a+ ++ tll+++s+D+++ vW+++
   Q: 103  GHENEVKCVAWaPSgTLLATCSRDKSVWVWEVD 135
           8***********666****************86 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdls...tgkcv 87
           +l++ h+  +++v++sp +++la++s d+t+ +w+ ++ ++  l  l+ghe+ev++v + p+g +l+t+s+D+ + vw+++    ++cv
   Q: 55   VLQDGHQRTVRKVAWSPCGNYLASASFDATTCIWKKKNDDFesLTVLEGHENEVKCVAWAPSGTLLATCSRDKSVWVWEVDeedEYECV 143
           578889999999**************************999988999*******************************8777779**** PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......... 166
            +++ h+++v  + ++p+++ l+s+s d+ i +++ e + +    tl+gh+++v++++++ +g+ l+s+s+Drtv++W+          
   Q: 144  TVVNSHTQDVKHVVWHPTQELLASASYDNNICIYKEEDDDWECRaTLQGHTSTVWSLCFDVTGQRLASCSDDRTVKIWKEypitecfvw 232
           **********************************99887665545**********************************9********* PP
   S: 167  ......ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvkl 206
                  + k++ tl+g+h + vy +++ +    l+++  d  +++
   Q: 233  sallgdLSWKCVCTLSGYHGRTVYDIAWCRLTGALATACGDDAIRV 278
           ****************************999999999999999987 PP

Organism

Oryzias latipes

Functional Description
(View)

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MKEAISLVQK LSAHPDSRCW FVSWSPSGAL LASCGGDKAI RIWGQEGDSW VCKNVLQDGH 60
QRTVRKVAWS PCGNYLASAS FDATTCIWKK KNDDFESLTV LEGHENEVKC VAWAPSGTLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCACGTTTG CTGGAGCTCT GCCATGAAGG AGGCTATTTC TCTGGTGCAG AAACTCAGCG 60
CACACCCAGA TTCTCGGTGC TGGTTCGTCA GTTGGAGCCC GAGCGGTGCG CTGCTGGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	47.97	6.00e-66	245.00
IUUC-Aml-001317	Ailuropoda melanoleuca	72.94	7.00e-138	483.00
IUUC-Atr-003029	Amborella trichopoda	50.58	5.00e-89	320.00
IUUC-Apl-004042	Anas platyrhynchos	62.70	4.00e-37	146.00
IUUC-Aly-005812	Arabidopsis lyrata	48.51	1.00e-83	302.00
IUUC-Ath-006671	Arabidopsis thaliana	48.31	6.00e-85	307.00
IUUC-Ago-007820	Ashbya gossypii	41.35	2.00e-60	225.00
IUUC-Acl-008042	Aspergillus clavatus	30.28	3.00e-45	176.00
IUUC-Afl-008639	Aspergillus flavus	31.26	1.00e-49	190.00
IUUC-Afu-008899	Aspergillus fumigatus	28.64	1.00e-43	170.00
IUUC-Ani-009453	Aspergillus nidulans	29.95	1.00e-48	187.00
IUUC-Ang-009758	Aspergillus niger	39.84	2.00e-43	169.00
IUUC-Aor-010212	Aspergillus oryzae	31.26	1.00e-49	190.00
IUUC-Ate-010314	Aspergillus terreus	30.70	8.00e-48	184.00
IUUC-Ame-010676	Astyanax mexicanus	78.47	1.00e-157	548.00
IUUC-Bgr-012095	Blumeria graminis	29.45	2.00e-35	142.00
IUUC-Bta-012884	Bos taurus	72.94	2.00e-137	481.00
IUUC-Bci-013622	Botrytis cinerea	29.97	1.00e-32	133.00
IUUC-Bdi-014614	Brachypodium distachyon	47.76	3.00e-83	301.00
IUUC-Bol-016439	Brassica oleracea	47.18	2.00e-81	295.00
IUUC-Bra-016830	Brassica rapa	46.43	1.00e-80	293.00
IUUC-Cel-018709	Caenorhabditis elegans	39.76	5.00e-63	234.00
IUUC-Cja-019822	Callithrix jacchus	72.86	1.00e-137	482.00
IUUC-Cfa-020823	Canis familiaris	72.94	2.00e-138	484.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	47.29	1.00e-78	286.00
IUUC-Csa-023754	Chlorocebus sabaeus	73.53	1.00e-138	485.00
IUUC-Cin-025395	Ciona intestinalis	55.52	2.00e-107	381.00
IUUC-Csv-025943	Ciona savignyi	54.05	4.00e-104	370.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	30.98	2.00e-31	130.00
IUUC-Cne-026939	Cryptococcus neoformans	29.38	1.00e-42	167.00
IUUC-Cme-027239	Cyanidioschyzon merolae	40.93	2.00e-41	163.00
IUUC-Dre-028172	Danio rerio	77.25	1.00e-155	541.00
IUUC-Dno-029472	Dasypus novemcinctus	75.17	3.00e-116	410.00
IUUC-Dor-031134	Dipodomys ordii	62.65	1.00e-110	392.00
IUUC-Dse-031535	Dothistroma septosporum	27.01	2.00e-40	160.00
IUUC-Dme-032020	Drosophila melanogaster	57.40	1.00e-110	392.00
IUUC-Eca-033700	Equus caballus	72.57	2.00e-139	488.00
IUUC-Eeu-035010	Erinaceus europaeus	70.50	6.00e-133	466.00
IUUC-Fca-036309	Felis catus	65.29	8.00e-130	456.00
IUUC-Fal-037243	Ficedula albicollis	64.19	1.00e-74	271.00
IUUC-Fox-038058	Fusarium oxysporum	29.32	8.00e-37	148.00
IUUC-Fso-038459	Fusarium solani	32.78	3.00e-33	135.00
IUUC-Gmo-039375	Gadus morhua	78.44	2.00e-145	507.00
IUUC-Ggr-040002	Gaeumannomyces graminis	31.67	7.00e-34	138.00
IUUC-Gga-040294	Gallus gallus	71.57	2.00e-105	375.00
IUUC-Gac-042499	Gasterosteus aculeatus	85.42	2.00e-156	544.00
IUUC-Gma-043543	Glycine max	48.24	8.00e-89	320.00
IUUC-Ggo-045181	Gorilla gorilla	73.53	1.00e-138	485.00
IUUC-Hsa-046528	Homo sapiens	73.53	1.00e-138	485.00
IUUC-Hvu-047341	Hordeum vulgare	53.68	2.00e-53	201.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	73.53	3.00e-139	487.00
IUUC-Kpa-049353	Komagataella pastoris	35.49	7.00e-53	200.00
IUUC-Lch-049763	Latimeria chalumnae	72.40	2.00e-140	491.00
IUUC-Lpe-051500	Leersia perrieri	44.15	7.00e-82	297.00
IUUC-Loc-052021	Lepisosteus oculatus	76.33	1.00e-140	492.00
IUUC-Lma-053331	Leptosphaeria maculans	31.93	2.00e-49	190.00
IUUC-Laf-054558	Loxodonta africana	72.94	2.00e-137	481.00
IUUC-Mcc-055374	Macaca mulatta	73.53	1.00e-138	485.00
IUUC-Meu-056042	Macropus eugenii	62.68	1.00e-83	301.00
IUUC-Mor-057187	Magnaporthe oryzae	28.51	2.00e-33	136.00
IUUC-Mtr-058072	Medicago truncatula	49.70	5.00e-89	320.00
IUUC-Mla-059108	Melampsora laricipopulina	31.98	3.00e-51	196.00
IUUC-Mga-059370	Meleagris gallopavo	55.22	2.00e-81	295.00
IUUC-Mvi-060495	Microbotryum violaceum	37.10	9.00e-55	207.00
IUUC-Mmr-060902	Microcebus murinus	73.24	3.00e-139	487.00
IUUC-Mdo-062510	Monodelphis domestica	72.65	1.00e-134	471.00
IUUC-Mmu-063575	Mus musculus	73.24	6.00e-138	483.00
IUUC-Mac-065322	Musa acuminata	49.55	2.00e-89	322.00
IUUC-Mpu-065925	Mustela putorius furo	72.65	1.00e-138	485.00
IUUC-Mlu-067755	Myotis lucifugus	72.65	3.00e-137	481.00
IUUC-Nfi-068327	Neosartorya fischeri	29.44	7.00e-44	171.00
IUUC-Ncr-068845	Neurospora crassa	27.43	2.00e-25	109.00
IUUC-Nle-069406	Nomascus leucogenys	72.06	1.00e-133	468.00
IUUC-Opr-070416	Ochotona princeps	81.60	3.00e-67	248.00
IUUC-Ont-071936	Oreochromis niloticus	87.80	8.00e-164	569.00
IUUC-Oan-073452	Ornithorhynchus anatinus	73.17	3.00e-53	200.00
IUUC-Ocu-074791	Oryctolagus cuniculus	73.90	3.00e-138	484.00
IUUC-Oba-075636	Oryza barthii	48.10	1.00e-86	313.00
IUUC-Obr-076742	Oryza brachyantha	49.32	5.00e-77	280.00
IUUC-Ogl-077766	Oryza glaberrima	48.10	1.00e-86	313.00
IUUC-Ogu-079039	Oryza glumaepatula	48.10	8.00e-87	313.00
IUUC-Oin-079315	Oryza indica	48.15	1.00e-75	276.00
IUUC-Olo-080669	Oryza longistaminata	42.82	8.00e-79	287.00
IUUC-Ome-081490	Oryza meridionalis	47.97	7.00e-87	313.00
IUUC-Oni-082572	Oryza nivara	48.10	1.00e-86	313.00
IUUC-Opu-083732	Oryza punctata	49.27	9.00e-88	316.00
IUUC-Oru-084763	Oryza rufipogon	48.10	1.00e-86	313.00
IUUC-Osa-085372	Oryza sativa	48.10	1.00e-86	313.00
IUUC-Olu-087801	Ostreococcus lucimarinus	33.63	8.00e-41	160.00
IUUC-Oga-089076	Otolemur garnettii	73.82	6.00e-140	489.00
IUUC-Oar-090022	Ovis aries	74.33	7.00e-139	486.00
IUUC-Ptr-090809	Pan troglodytes	73.53	1.00e-138	485.00
IUUC-Pan-091685	Papio anubis	73.53	1.00e-140	493.00
IUUC-Psi-093046	Pelodiscus sinensis	71.64	4.00e-136	477.00
IUUC-Pma-094181	Petromyzon marinus	62.24	7.00e-127	446.00
IUUC-Pno-094882	Phaeosphaeria nodorum	30.22	4.00e-50	192.00
IUUC-Ppa-095172	Physcomitrella patens	47.67	7.00e-85	306.00
IUUC-Pfo-096396	Poecilia formosa	84.23	8.00e-160	555.00
IUUC-Pab-098427	Pongo abelii	73.24	1.00e-136	479.00
IUUC-Pop-100016	Populus trichocarpa	49.85	8.00e-90	323.00
IUUC-Pca-101048	Procavia capensis	73.51	4.00e-137	480.00
IUUC-Ppe-102050	Prunus persica	45.92	3.00e-84	305.00
IUUC-Pva-103117	Pteropus vampyrus	72.94	3.00e-138	484.00
IUUC-Pgr-103307	Puccinia graminis	34.62	1.00e-56	213.00
IUUC-Ptt-103938	Puccinia triticina	37.93	5.00e-45	174.00
IUUC-Pte-104315	Pyrenophora teres	30.62	5.00e-49	188.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	30.86	1.00e-49	190.00
IUUC-Rno-105523	Rattus norvegicus	74.12	4.00e-139	487.00
IUUC-Sce-106297	Saccharomyces cerevisiae	39.20	4.00e-61	228.00
IUUC-Sha-106981	Sarcophilus harrisii	75.52	4.00e-113	400.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	37.65	1.00e-52	201.00
IUUC-Spo-108214	Schizosaccharomyces pombe	39.81	2.00e-57	216.00
IUUC-Smo-109034	Selaginella moellendorffii	46.48	2.00e-84	305.00
IUUC-Sit-110663	Setaria italica	48.81	3.00e-88	318.00
IUUC-Sly-110898	Solanum lycopersicum	46.53	3.00e-79	288.00
IUUC-Stu-112647	Solanum tuberosum	50.00	1.00e-68	252.00
IUUC-Sbi-114288	Sorghum bicolor	47.04	1.00e-85	309.00
IUUC-Sre-115065	Sporisorium reilianum	38.73	1.00e-63	237.00
IUUC-Ssc-115960	Sus scrofa	68.96	1.00e-138	485.00
IUUC-Tru-118382	Takifugu rubripes	80.36	2.00e-160	558.00
IUUC-Tsy-119585	Tarsius syrichta	65.29	6.00e-118	416.00
IUUC-Tni-120133	Tetraodon nigroviridis	81.93	2.00e-153	535.00
IUUC-Tca-121167	Theobroma cacao	48.24	2.00e-80	292.00
IUUC-Tre-122119	Trichoderma reesei	28.21	4.00e-36	145.00
IUUC-Tvi-122407	Trichoderma virens	28.87	1.00e-37	150.00
IUUC-Tae-124500	Triticum aestivum	46.63	8.00e-81	293.00
IUUC-Tur-126682	Triticum urartu	48.31	1.00e-66	246.00
IUUC-Tme-127095	Tuber melanosporum	35.42	3.00e-56	212.00
IUUC-Tbe-128004	Tupaia belangeri	72.94	2.00e-138	484.00
IUUC-Ttr-129284	Tursiops truncatus	71.43	4.00e-133	467.00
IUUC-Uma-129527	Ustilago maydis	35.65	5.00e-64	238.00
IUUC-Vda-129854	Verticillium dahliae	28.34	1.00e-32	134.00
IUUC-Vpa-130681	Vicugna pacos	88.79	2.00e-45	176.00
IUUC-Vvi-131004	Vitis vinifera	51.50	6.00e-86	310.00
IUUC-Xtr-131928	Xenopus tropicalis	69.85	1.00e-132	465.00
IUUC-Xma-134290	Xiphophorus maculatus	83.04	3.00e-156	543.00
IUUC-Yli-134364	Yarrowia lipolytica	40.17	4.00e-61	228.00
IUUC-Zma-135658	Zea mays	47.34	2.00e-85	308.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence