iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089732

Ensembl Protein ID

ENSOARP00000014330.1

UniProt Accession

W5PV48; W5PV48_SHEEP

Genbank Protein ID

ENSOARP00000014330

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01115582

Gene Name

USP11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000013365.1	ENSOART00000014539.1	ENSOARP00000014330.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.90e-112	375.4	307	933

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+ ++ e+ln  np ++kge+++++++l+++ w+++++++ p+ ++++++++a++f gy+
   Q: 307  CGLTNLGNTCFMNSALQCLSNVPQLTEYFLKnRYLEELNFCNPLGMKGEIAQAYADLVKQAWSGHHRSIVPQVFKTKVGHFASQFLGYQ 395
           7*****************************999******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++ +  ++    a++++k++n+s+i+d+F+g +ks+++c++c+nvs++++pf++ls+
   Q: 396  QHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVaqeAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSV 484
           *****************************998874333322555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++++ +e                                                                              
   Q: 485  PLPVSHKRVMEvffvsmdprrkpeqhrlvvpkkgkisdlcvalakhtgispermmvadvfshrfykiyqleeslssildrddifiyevs 573
           ******99988****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 574  graaigensredvvlpiylrertpardynssyyglmlfghpllvsvprdrlswdalyhillyrlsryvtrpssddeddgdekgeeeedl 662
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 663  edkdslpkpghvtegssqdpgleqagpssrvvsgsrapvdnspgpshwpqrarrkhlftlhtvnsngtsdrstfnedthaqpyiaidwe 751
           ***************************************************************************************** PP
   S: 186  ...............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeq 243
                                          +lq+c+e ft+ e+le+en +yc++ck++q a+kkl+l+ lPe+Li+hLkRfs+++  
   Q: 752  pemkkryydeveaegyvkhdcvgyvlkkapvQLQECIELFTTVETLEKENPWYCPTCKQHQLATKKLDLWMLPETLIIHLKRFSYTK-- 838
           ***********************************************************************************8866.. PP
   S: 244  ksrekinkkvefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgst 329
            srek+++ vefp++ Ld s+f+++p++++++  +kY+Liav +H+G+l+ GHY++++ n ++g+W +fdDs+V++v+e+++++   + 
   Q: 839  FSREKLDTLVEFPIRdLDFSEFVIKPQNDSAReLYKYDLIAVSNHYGGLRDGHYTTFACNkDSGQWHYFDDSSVSPVTENQIES---KA 924
           89********************9999887754489*********************988834566*******************...** PP
   S: 330  aYvlfYkrr 338
           aYvlfY+r+
   Q: 925  AYVLFYQRQ 933
           *******96 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

TAVAPWLYGG LCFRFRDQNP EVALEGPFLV PAAVAARGGQ TAMAAVAAKR CQAWRASGAG 60
LVIREKKKKN NSNFPTLQFF FLQILHTTSN CATPLSPVWS RFLVGQHWYK QWEVYVQGGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGCAGTAG CCCCCTGGCT GTATGGGGGG CTCTGCTTCC GTTTCCGGGA CCAAAATCCG 60
GAAGTGGCAC TTGAGGGGCC CTTCCTAGTC CCAGCTGCGG TGGCCGCTAG AGGAGGGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	88.13	0.00e+00	1611.00
IUUC-Aca-004532	Anolis carolinensis	67.44	0.00e+00	1123.00
IUUC-Afl-008507	Aspergillus flavus	34.72	4.00e-54	207.00
IUUC-Afu-008878	Aspergillus fumigatus	35.53	1.00e-56	215.00
IUUC-Aor-009949	Aspergillus oryzae	34.50	3.00e-53	203.00
IUUC-Ate-010323	Aspergillus terreus	36.87	5.00e-57	216.00
IUUC-Bta-013284	Bos taurus	95.99	0.00e+00	1639.00
IUUC-Cja-019746	Callithrix jacchus	79.84	0.00e+00	1421.00
IUUC-Cfa-020134	Canis familiaris	87.88	0.00e+00	1672.00
IUUC-Cpo-022535	Cavia porcellus	75.11	0.00e+00	1390.00
IUUC-Csa-023828	Chlorocebus sabaeus	78.70	0.00e+00	1491.00
IUUC-Dre-027398	Danio rerio	63.07	0.00e+00	719.00
IUUC-Dno-028853	Dasypus novemcinctus	86.16	0.00e+00	1356.00
IUUC-Dor-030384	Dipodomys ordii	76.04	0.00e+00	1411.00
IUUC-Eca-033271	Equus caballus	89.58	0.00e+00	1595.00
IUUC-Fca-036012	Felis catus	88.47	0.00e+00	1617.00
IUUC-Gac-042574	Gasterosteus aculeatus	55.28	0.00e+00	879.00
IUUC-Hsa-046551	Homo sapiens	78.70	0.00e+00	1487.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	76.82	0.00e+00	1429.00
IUUC-Kpa-049332	Komagataella pastoris	33.39	9.00e-68	252.00
IUUC-Laf-054561	Loxodonta africana	80.43	0.00e+00	1553.00
IUUC-Mcc-054881	Macaca mulatta	78.49	0.00e+00	1489.00
IUUC-Meu-056749	Macropus eugenii	83.40	0.00e+00	937.00
IUUC-Mla-058848	Melampsora laricipopulina	41.44	7.00e-72	266.00
IUUC-Mvi-060324	Microbotryum violaceum	32.21	2.00e-77	284.00
IUUC-Mmr-061400	Microcebus murinus	83.04	0.00e+00	1489.00
IUUC-Mdo-062470	Monodelphis domestica	82.01	0.00e+00	807.00
IUUC-Mmu-063241	Mus musculus	75.65	0.00e+00	1363.00
IUUC-Mac-064956	Musa acuminata	35.81	4.00e-133	468.00
IUUC-Mpu-066507	Mustela putorius furo	87.71	0.00e+00	1641.00
IUUC-Mlu-066961	Myotis lucifugus	83.28	0.00e+00	1454.00
IUUC-Nfi-068330	Neosartorya fischeri	38.46	4.00e-55	210.00
IUUC-Nle-069284	Nomascus leucogenys	80.51	0.00e+00	1450.00
IUUC-Ont-071847	Oreochromis niloticus	59.13	0.00e+00	958.00
IUUC-Oan-073387	Ornithorhynchus anatinus	75.17	0.00e+00	861.00
IUUC-Ocu-074066	Oryctolagus cuniculus	77.02	0.00e+00	1460.00
IUUC-Oga-088424	Otolemur garnettii	82.06	0.00e+00	1467.00
IUUC-Pan-092292	Papio anubis	79.15	0.00e+00	1489.00
IUUC-Pab-098779	Pongo abelii	71.60	0.00e+00	1234.00
IUUC-Pca-100851	Procavia capensis	77.93	0.00e+00	914.00
IUUC-Pva-103244	Pteropus vampyrus	83.98	0.00e+00	1568.00
IUUC-Ptt-103847	Puccinia triticina	36.04	9.00e-64	239.00
IUUC-Rno-105100	Rattus norvegicus	77.20	0.00e+00	1364.00
IUUC-Sce-106170	Saccharomyces cerevisiae	37.90	2.00e-60	228.00
IUUC-Sha-107502	Sarcophilus harrisii	81.51	0.00e+00	925.00
IUUC-Ssc-116345	Sus scrofa	89.42	0.00e+00	1638.00
IUUC-Tru-117788	Takifugu rubripes	57.49	0.00e+00	915.00
IUUC-Tsy-119414	Tarsius syrichta	71.45	0.00e+00	1030.00
IUUC-Tni-120107	Tetraodon nigroviridis	51.98	6.00e-158	551.00
IUUC-Tvi-122422	Trichoderma virens	41.54	6.00e-58	220.00
IUUC-Tbe-128081	Tupaia belangeri	86.22	0.00e+00	974.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence