iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092928

Ensembl Protein ID

ENSPANP00000011408.1

UniProt Accession

A0A096NES8; A0A096NES8_PAPAN

Genbank Protein ID

ENSPANP00000011408

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01105858

Gene Name

USP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000003766.1	ENSPANT00000017371.1	ENSPANP00000011408.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.20e-77	258.9	297	878

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklf..eelwkskkkavsprellkalkkeaeefsgy 87
           +Gl NlgNtCYmN+vLQ+L++ip+++++ll+   +++++   k p ++l+++l++l+  +  ++ + k +   +++ka++++ae f+g+
   Q: 297  HGLPNLGNTCYMNAVLQSLLSIPSFADDLLN---QSFPWG--KIPLNALTMCLARLLflKDTYNVEIKEMLLLNIKKAISAVAEIFHGN 380
           59*****************************...9****9..67999999999998711444599999********************* PP
   S: 88   eqqDaqEflaflldqleeelkk.eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           +q+Da+Efla++ldql+++++k ++ ++ ++e++ed+  +   a++ +++  ++++ ++F+ +l ++i c++c++v  ++e  ++ls++
   Q: 381  AQNDAHEFLAHCLDQLKDNMEKlNTIWKPKSEFGEDNFPKRIFADDPDTNGFSCPVITNFELELLHSIACKACGQVILKTE-LNYLSIN 468
           ********************8888999999999********************************************9987.699**** PP
   S: 176  vpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           +p+  +  ++s+    +s + +eele    y+c kck+k+ ++  +++++lP++Li+hLkR++ ++  +s +k+ ++v + + L++s++
   Q: 469  LPQGMKARPSSI----QSTFGAEELE----YKCAKCKHKT-SVGVHSFSRLPRILIVHLKRYNLNKF-CSLKKNGREVVISKYLKVSSH 547
           **9998866655....566799***9....*******999.7999*****************99887.9999***************** PP
   S: 265  cts...................................................................................... 267
           c++                                                                                      
   Q: 548  CNEgtrpplplsedgeitdfqllkvirkmtsgsisvswpstkepkdilashigsdtesgqtvfkgasrrqqqkylgknskpnepesvys 636
           *******************************************9999999999999999999999999999999999999999999999 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 637  gdrafiekeplahlmayledtslcqfhkaggkpasspdtclaevhfqtvpenpkrkkymktskfvafdsiinrtkdlyedknvrilkrf 725
           99999988888888888888888888888888888888888888888888888888888888888888888888888877777777777 PP
   S: 268  .........................................................................peekqke......... 274
                                                                                          +         
   Q: 726  qkvseqtqqcdamriceqapqqalprsfpkpgaqghtknlikpaklnlqkpnrnslpalgsnknprnkdildkI-----Kskvketkrn 809
           77777777777777777776666666666666666666666666666666666666666555555555555550.....0555555556 PP
   S: 275  ....kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
               +++Y+Li+vv+H G +l+sGHY++++++ +++ W++++D +V  ++e++++e++++t+Y++fY++
   Q: 810  ddkgDHTYRLISVVSHLGkTLKSGHYICDAYDFEKQiWFTYNDMQVLGIQEAQMQEDRRCTGYIFFYMH 878
           6666****************************9999*******************************98 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAALFLHGFV QIGNCKTGMS KSKESFIEAV EGRKKDRLVL YFKNGKCNTF QLSDNIQNIV 60
LRSCRGNQNH LHLTLQNNNV LFIEGLSSTD AEQLKTFLDR VHQNKVQSPV RPGKGRNVFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCCC TATTCCTACA TGGTTTTGTC CAAATAGGGA ACTGCAAGAC TGGGATGTCT 60
AAGTCAAAAG AATCATTCAT TGAAGCAGTG GAAGGAAGGA AGAAAGATAG ATTGGTGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002281	Ailuropoda melanoleuca	57.64	0.00e+00	930.00
IUUC-Bta-012832	Bos taurus	46.19	0.00e+00	676.00
IUUC-Cja-019801	Callithrix jacchus	74.10	0.00e+00	1337.00
IUUC-Cfa-020088	Canis familiaris	57.24	0.00e+00	958.00
IUUC-Cpo-022049	Cavia porcellus	41.84	5.00e-175	608.00
IUUC-Csa-023990	Chlorocebus sabaeus	96.61	0.00e+00	1757.00
IUUC-Dno-028968	Dasypus novemcinctus	46.15	0.00e+00	708.00
IUUC-Dor-030370	Dipodomys ordii	43.23	0.00e+00	664.00
IUUC-Ete-033046	Echinops telfairi	42.82	4.00e-85	308.00
IUUC-Eca-034060	Equus caballus	57.25	0.00e+00	899.00
IUUC-Fca-035628	Felis catus	56.01	0.00e+00	905.00
IUUC-Ggr-039843	Gaeumannomyces graminis	52.17	7.00e-09	57.00
IUUC-Ggo-045311	Gorilla gorilla	90.71	0.00e+00	1636.00
IUUC-Hsa-046292	Homo sapiens	90.38	0.00e+00	1622.00
IUUC-Itr-047983	Ictidomys tridecemlineatus	54.14	0.00e+00	890.00
IUUC-Laf-054311	Loxodonta africana	50.67	0.00e+00	768.00
IUUC-Mcc-055452	Macaca mulatta	47.27	0.00e+00	730.00
IUUC-Mor-057281	Magnaporthe oryzae	47.83	4.00e-08	54.30
IUUC-Mmr-061542	Microcebus murinus	61.93	0.00e+00	1040.00
IUUC-Mpu-066846	Mustela putorius furo	54.70	0.00e+00	900.00
IUUC-Mlu-068224	Myotis lucifugus	56.89	0.00e+00	889.00
IUUC-Nle-069425	Nomascus leucogenys	46.47	0.00e+00	714.00
IUUC-Ocu-073860	Oryctolagus cuniculus	51.68	0.00e+00	825.00
IUUC-Oga-088020	Otolemur garnettii	47.85	0.00e+00	725.00
IUUC-Oar-089263	Ovis aries	47.07	0.00e+00	706.00
IUUC-Ptr-090973	Pan troglodytes	85.24	0.00e+00	674.00
IUUC-Pab-098555	Pongo abelii	91.91	0.00e+00	1697.00
IUUC-Pca-100925	Procavia capensis	44.77	0.00e+00	657.00
IUUC-Sar-113624	Sorex araneus	45.01	5.00e-175	608.00
IUUC-Ssc-116225	Sus scrofa	57.24	0.00e+00	947.00
IUUC-Tsy-119113	Tarsius syrichta	45.15	0.00e+00	660.00
IUUC-Tbe-127615	Tupaia belangeri	53.23	2.00e-120	426.00
IUUC-Ttr-129071	Tursiops truncatus	49.35	0.00e+00	788.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence